Personkort bilde
Head of Office

Ronny Helland

Head of Administration, Department of Chemistry Department of Chemistry
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My research interests include structure-function studies of proteins (enzymes): How does the atomic structure affect an enzyme's activity, specificity and efficiency. Enzymes which originates from cold adapted organisms often have unique properties. These we want to find use for in biochemical and biotechnological industries.

 

Participate in:

The Norwegian Structural Biology Centre
Bacterial sialic acids
MarSynth – Marine DNA modifying enzymes for synthetic biology
Optimization and Application Development of Marine Cold-adapted DNA Polymerases – OptiZyme

  • Mazurkewich, Scott; Helland, Ronny; Mackenzie, Alasdair; Eijsink, Vincent; Pope, Phillip Byron; Brändén, Gisela; Larsbrink, Johan. Structural insights of the enzymes from the chitin utilization locus of Flavobacterium johnsoniae. Scientific Reports 2020. ISSN 2045-2322.s doi: 10.1038/s41598-020-70749-w.

  • Hjörleifsson, Jens Guðmundur; Helland, Ronny; Magnusdottir, Manuela; Ásgeirsson, Bjarni. The high catalytic rate of the cold-active Vibrio alkaline phosphatase requires a hydrogen bonding network involving a large interface loop. FEBS Open Bio 2020; Volum 11 (1). ISSN 2211-5463.s 173 - 184.s doi: 10.1002/2211-5463.13041.

  • Ásgeirsson, Bjarni; Markússon, Sigurbjörn; Hlynsdóttir, Sigríður S.; Helland, Ronny; Hjörleifsson, Jens G.. X-ray crystal structure of Vibrio alkaline phosphatase with the non-competitive inhibitor cyclohexylamine. Biochemistry and Biophysics Reports 2020; Volum 24. ISSN 2405-5808.s doi: https://doi.org/10.1016/j.bbrep.2020.100830.

  • Gurung, Man Kumari; Altermark, Bjørn; Helland, Ronny; Smalås, Arne O.; Ræder, Inger Lin Uttakleiv. Features and structure of a cold active N-acetylneuraminate lyase. (Fulltekst: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0217713&type=printable PLOS ONE 2019; Volum 14 (6). ISSN 1932-6203.s 1 - 27.s doi: 10.1371/journal.pone.0217713.

  • Helland, Ronny; Bjørkeng, Eva katrin; Rothweiler, Ulli; Sydnes, Magne Olav; Pampanin, Daniela Maria. The crystal structure of haemoglobin from Atlantic cod. Acta Crystallographica. Section F : Structural Biology and Crystallization Communications 2019; Volum F75 (8). ISSN 1744-3091.s 537 - 542.s doi: 10.1107/S2053230X1900904X.

  • De Santi, Concetta; Gani, Osman A. B. S. M.; Helland, Ronny; Williamson, Adele Kim. Structural insight into a CE15 esterase from the marine bacterial metagenome. Scientific Reports 2017; Volum 7:17278. ISSN 2045-2322.s 1 - 10.s doi: 10.1038/s41598-017-17677-4.

  • Seppola, Marit; Bakkemo, Kathrine Ryvold; Mikkelsen, Helene V.; Myrnes, Bjørnar; Helland, Ronny; Irwin, David; Nilsen, Inge Waller. Multiple specialised goose-type lysozymes potentially compensate for an exceptional lack of chickentype lysozymes in Atlantic cod. (Fulltekst: file://homer.uit.no/ini031/My%20Documents/New%20science/SciRep/Published_srep28318_210616.pdf Scientific Reports 2016; Volum 6. ISSN 2045-2322.s doi: 10.1038/srep28318.

  • Christopeit, Tony; Carlsen, Trine Josefine Olsen; Helland, Ronny; Leiros, Hanna-Kirsti S.. Discovery of novel inhibitor scaffolds against the metallo-β-lactamase VIM-2 by surface plasmon resonance (SPR) based fragment screening. Journal of Medicinal Chemistry 2015; Volum 58 (21). ISSN 0022-2623.s 8671 - 8682.s doi: 10.1021/acs.jmedchem.5b01289.

  • Lysvand, Hilde; Helland, Ronny; Hagen, Lars; Slupphaug, Geir; Iversen, Ole-Jan. Psoriasis pathogenesis – Pso p27 constitutes a compact structure forming large aggregates. Biochemistry and Biophysics Reports 2015; Volum 2. ISSN 2405-5808.s 132 - 136.s doi: 10.1016/j.bbrep.2015.06.001.

  • Forsberg, Zarah; Mackenzie, Alasdair; Sørlie, Morten; Røhr, Åsmund Kjendseth; Helland, Ronny; Arvai, Andrew S.; Vaaje-Kolstad, Gustav; Eijsink, Vincent. Structural and functional characterization of a conserved pair of bacterial cellulose-oxidizing lytic polysaccharide monooxygenases. Proceedings of the National Academy of Sciences of the United States of America 2014; Volum 111 (23). ISSN 0027-8424.s 8446 - 8451.s doi: 10.1073/pnas.1402771111.

  • Johnson, Kenneth; Ve, Thomas; Larsen, Øivind; Pedersen, Rolf B.; Lillehaug, Johan R.; Jensen, Harald B; Helland, Ronny; Karlsen, Odd Andre. CorA is a copper repressible surface-associated copper(I)-binding protein produced in Methylomicrobium album BG8. PLOS ONE 2014; Volum 9 (2:e87750). ISSN 1932-6203.s doi: 10.1371/journal.pone.0087750.

  • Cazamea-Catalan, D.; Magnanou, E.; Helland, Ronny; Besseau, L.; Boeuf, Gilles; Falcòn, Jack; Jørgensen, Even Hjalmar. Unique arylalkylamine N-acetyltransferase-2 polymorphism in salmonids and profound variations in thermal stability and catalytic efficiency conferred by two residues. Journal of Experimental Biology 2013; Volum 216 (10). ISSN 0022-0949.s 1938 - 1948.s doi: 10.1242/jeb.080960.

  • Ve, Thomas; Mathisen, Karina; Helland, Ronny; Karlsen, Odd Andre; Fjellbirkeland, Anne; Røhr, Åsmund Kjendseth; Andersson, K. Kristoffer; Pedersen, Rolf B.; Lillehaug, Johan R.; Jensen, Harald B. The Methylococcus capsulatus (Bath) Secreted Protein, MopE*, Binds Both Reduced and Oxidized Copper. PLOS ONE 2012; Volum 7 (8). ISSN 1932-6203.s doi: 10.1371/journal.pone.0043146.

  • Lagos, Leidy; Iliev, Dimitar Borisov; Helland, Ronny; Rosemblatt, Mario; Jørgensen, Jorunn B. CD40L-A costimulatory molecule involved in the maturation of antigen presenting cells in Atlantic salmon (Salmo salar). Developmental and Comparative Immunology 2012; Volum 38 (3). ISSN 0145-305X.s 416 - 430.s doi: 10.1016/j.dci.2012.07.011.

  • D. Cazamèa-Catalan, Damien; Magnanou, Elodie; Helland, Ronny; Vanegas, Gilmer; Besseau, Laurence; Boeuf, Gilles; Paulin, Charles-Hubert; Jørgensen, Even Hjalmar; Falcòn, Jack. Functional diversity of Teleost arylalkylamine N-acetyltransferase-2: is the timezyme evolution driven by habitat temperature?. Molecular Ecology 2012; Volum 21 (20). ISSN 0962-1083.s 5027 - 5041.s doi: 10.1111/j.1365-294X.2012.05725.x.

  • Kyomuhendo, Peter; Myrnes, Bjørnar; Brandsdal, Bjørn Olav; Smalås, Arne; Nilsen, Inge Waller; Helland, Ronny. Thermodynamics and structure of a salmon cold active goose-type lysozyme. Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology 2010; Volum 156 (4). ISSN 1096-4959.s 254 - 263.s doi: 10.1016/j.cbpb.2010.04.002.

  • Helland, Ronny; Larsen, Renate Lie; Åsgeirsson, Bjarni. The 1.4 angstrom crystal structure of the large and cold-active Vibrio sp. alkaline phosphatase. Biochimica et Biophysica Acta - Proteins and Proteomics 2009; Volum 1794 (2). ISSN 1570-9639.s 297 - 308.s doi: 10.1016/j.bbapap.2008.09.020.

  • Helland, Ronny; Larsen, Renate Lie; Finstad, Solrun; Kyomuhendo, Peter; Larsen, Atle Noralf. Crystal structures of g-type lysozyme from Atlantic cod shed new light on substrate binding and the catalytic mechanism. Cellular and Molecular Life Sciences (CMLS) 2009; Volum 66 (15). ISSN 1420-682X.s 2585 - 2598.s doi: 10.1007/s00018-009-0063-x.

  • Szlachcic, Anna; Zakrzewska, M; Krowarsch, D; Os, vibeke; Helland, Ronny; Smalås, Arne Oskar; Otlewski, J. Structure of a highly stable mutant of human fibroblast growth factor 1. Acta Crystallographica Section D: Biological Crystallography 2009; Volum 65. ISSN 0907-4449.s 67 - 73.s doi: 10.1107/S0907444908039486.

  • Altermark, Bjørn; Helland, Ronny; Moe, Elin; Willassen, Nils Peder; Smalås, Arne Oskar. Structural adaptation of endonuclease I from the cold-adapted and halophilic bacterium Vibrio salmonicida. Acta Crystallographica Section D: Biological Crystallography 2008; Volum 64. ISSN 0907-4449.s 368 - 376.s doi: 10.1107/S0907444908000097.

  • Niiranen, Laila Mirja; Altermark, Bjørn; Brandsdal, Bjørn Olav; Leiros, Hanna-Kirsti S.; Helland, Ronny; Smalås, Arne Oskar; Willassen, Nils Peder. Effects of salt on the kinetics and thermodynamic stability of endonuclease I from Vibrio salmonicida and Vibrio cholerae. The FEBS Journal 2008; Volum 275. ISSN 1742-464X.s 1593 - 1605.s doi: 10.1111/j.1742-4658.2008.06317.x.

  • Altermark, Bjørn; Helland, Ronny; Moe, Elin; Willassen, Nils Peder; Smalås, Arne Oskar. Environmental adaptation of endonuclease I from Vibrio salmonicida. Acta Crystallographica Section D: Biological Crystallography 2008; Volum 64. ISSN 0907-4449.s 368 - 376.

  • Helland, Ronny; Fjellbirkeland, Anne; Karlsen, Odd-Arne; Lillehaug, Johan Richard; Jensen, Harald; Ve, Thomas. An oxidized tryptophan facilitates copper binding in Methylococcus capsulatus-secreted protein MopE. Journal of Biological Chemistry 2008; Volum 283 (20). ISSN 0021-9258.s 13897 - 13904.s doi: 10.1074/jbc.M800340200.

  • Riise, Ellen Kristin; Lorentzen, marit sjo; Helland, Ronny; Smalås, Arne Oskar; Leiros, Hanna-Kirsti S.; Willassen, Nils Peder. The first structure of a cold-active catalase from Vibrio salmonicida at 1.96 angstrom reveals structural aspects of cold adaptation. Acta Crystallographica Section D: Biological Crystallography 2007; Volum 63. ISSN 0907-4449.s 135 - 148.s doi: 10.1107/S0907444906043812.

  • Sælensminde, Gisle; Saelensminde, G; Halskau, Øyvind; Halskau, O; Helland, Ronny; Willassen, Nils Peder; Jonassen, I. Structure-dependent relationships between growth temperature of prokaryotes and the amino acid frequency in their proteins. Extremophiles 2007; Volum 11. ISSN 1431-0651.s 585 - 596.s doi: 10.1007/s00792-007-0072-3.

  • Larsen, Atle Noralf; Moe, Elin; Helland, Ronny; Gjellesvik, Dag Rune; Willassen, Nils Peder. Characterization of a recombinantly expressed proteinase K-like enzyme from a psychrotrophic Serratia sp. The FEBS Journal 2006; Volum 273 (1). ISSN 1742-464X.s 47 - 60.

  • Helland, Ronny; Larsen, Atle Noralf; Smalås, Arne Oskar; Willassen, Nils Peder. The 1.8 angstrom crystal structure of a proteinase K-like enzyme from a psychrotroph Serratia species. The FEBS Journal 2006; Volum 273. ISSN 1742-464X.

  • Adekoya, Olayiwola; Helland, Ronny; Willassen, Nils P; Sylte, Ingebrigt. Comparative sequence and structure analysis reveal features of cold adaptation of an enzyme in the thermolysin family. Proteins: Structure, Function, and Bioinformatics 2006; Volum 62. ISSN 0887-3585.

  • Riise, Ellen Kristin; Lorentzen, Marit Sjo; Helland, Ronny; Willassen, Nils P. Crystallization and preliminary X-ray diffraction analysis of a cold-adapted catalase from Vibrio salmonicida. Acta Crystallographica. Section F : Structural Biology and Crystallization Communications 2006; Volum 62 (1). ISSN 1744-3091.

  • Altermark, Bjørn; Smalås, Arne Oskar; Willassen, Nils Peder; Helland, Ronny. The structure of Vibrio cholerae extracellular endonuclease I reveals the presence of a buried chloride ion. Acta Crystallographica Section D: Biological Crystallography 2006; Volum 62. ISSN 0907-4449.s 1387 - 1391.

  • Czapinska, Honorata; Helland, Ronny; Smalås, Arne Oskar; Otlewski, Jacek. Crystal Structures of Five Bovine Chymotrypsin Complexes with P1 BPTI Variants. Journal of Molecular Biology (JMB) 2004; Volum 344 (4). ISSN 0022-2836.s 1005 - 1020.

  • Leiros, Hanna-Kirsti S.; Leiros, Hanna Kirsti Schrøder; Brandsdal, Bjørn Olav; Andersen, Ole Andreas; Os, vibeke; Leiros, Ingar; Leiros, Ingar; Helland, Ronny; Otlewski, J.; Otlewski, Jacek; Willassen, Nils Peder; Smalås, Arne Oskar. Trypsin specificity as elucidated by LIE calculations, X-ray structures, and association constant measurements. Protein Science 2004; Volum 13. ISSN 0961-8368.s 1056 - 1070.

  • Heikinheimo, Pirkko a; Helland, Ronny; Leiros, Hanna-Kirsti S.; Leiros, Ingar; Karlsen, Solveig; Evjen, gry; Ravelli, Raimond; Schoehn, Guy; Ruigrok, Rob; McSweeney, Sean; Hough, Edward. The structure of the bovine lysosomal a-mannosidase suggests a novel mechanism for low pH activation. Journal of Molecular Biology (JMB) 2003; Volum 327 (3). ISSN 0022-2836.s 631 - 644.

  • Helland, Ronny; Czapinska, Honorata; Leiros, Ingar; Olufsen, Magne; Otlewski, Jacek; Smalås, Arne Oskar. Structural Consequences of Accommodation of Four Non-cognate Amino Acid Residues in the S1 Pocket of Bovine Trypsin and Chymotrypsin. Journal of Molecular Biology (JMB) 2003; Volum 333 (4). ISSN 0022-2836.s 845 - 861.

  • Leiros, Ingar; Lanes, Olav; Sundheim, Ottar; Helland, Ronny; Smalås, Arne Oskar; Willassen, Nils Peder. Crystallization and preliminary X-ray diffraction analysis of a cold-adapted uracil-DNA glycosylase from Atlantic cod (Gadus morhua). Acta Crystallographica Section D: Biological Crystallography 2001; Volum 57. ISSN 0907-4449.s 1706 - 1708.

  • Gorfe, A.A.; Brandsdal, Bjørn Olav; Leiros, Hanna-Kirsti S.; Helland, Ronny; Smalås, Arne Oskar. Electrostatics of mesophilic and psychrophilic trypsin isoenzymes: qualitative evaluation of electrostatic differences at the substrate binding site. Proteins: Structure, Function, and Bioinformatics 2000; Volum 40. ISSN 0887-3585.s 207 - 217.

  • Grzesiak, Agnieszka; Helland, Ronny; Smalås, Arne Oskar; Krowarsch, Daniel; Dadlez, Michal; Otlewski, Jacek. Substitutions at the P(1) position in BPTI strongly affect the association energy with serine proteinases. Journal of Molecular Biology (JMB) 2000; Volum 301. ISSN 0022-2836.s 205 - 217.

  • Helland, Ronny; Berglund, Gunnar Inge; Otlewski, Jacek; Apostoluk, Wlodek; Andersen, Ole Andreas; Willassen, Nils Peder; Smalås, Arne Oskar. High-resolution structures of three new trypsin-squash-inhibitor complexes: a detailed comparison with other trypsins and their complexes. Acta Crystallographica Section D: Biological Crystallography 1999; Volum 55. ISSN 0907-4449.s 139 - 148.

  • Helland, Ronny; Otlewski, Jacek; Sundheim, Ottar; Dadlez, Michal; Smalås, Arne Oskar. The crystal structures of the complexes between bovine b-trypsin and ten P1 variants of BPTI. Journal of Molecular Biology (JMB) 1999; Volum 287. ISSN 0022-2836.s 923 - 942.

  • Helland, Ronny; Leiros, Ingar; Berglund, Gunnar Inge; Willassen, Nils Peder; Smalås, Arne Oskar. The crystal structure of anionic salmon trypsin in complex with bovine pancreatic trypsin inhibitor. European Journal of Biochemistry (EJB) 1998; Volum 256 (2). ISSN 0014-2956.s 317 - 324.

  • Gurung, Man Kumari; Berg, Tor Olav; Halsør, Marie-Josée Haglund; Altermark, Bjørn; Leiros, Ingar; Helland, Ronny; Rothweiler, Ulli; Smalås, Arne O.; Ræder, Inger Lin Uttakleiv. Efficient production of sialic acids- Using enzymes for biomass conversion. Eurocarb 2017 2017-07-02 - 2017-07-06 2017.

  • Gurung, Man Kumari; Berg, Tor Olav; Halsør, Marie-Josée Haglund; Altermark, Bjørn; Leiros, Ingar; Helland, Ronny; Rothweiler, Ulli; Smalås, Arne O.; Ræder, Inger Lin Uttakleiv. Efficient production of sialic acids- Using enzymes for biomass conversion. BIOPROSP2017 2017-03-08 - 2017-03-10 2017.

  • Berg, Tor Olav; Altermark, Bjørn; Leiros, Ingar; Helland, Ronny; Ræder, Inger Lin Uttakleiv. Production of sialic acids and derivatives by enzyme catalysis. NBS Contact meeting 2016 2016-01-21 - 2016-01-23 2016.

  • Berg, Tor Olav; Halsør, Marie-Josée Haglund; Gurung, Man Kumari; Altermark, Bjørn; Leiros, Ingar; Rothweiler, Ulli; Helland, Ronny; Smalås, Arne O.; Ræder, Inger Lin Uttakleiv. From marine rest raw materials to sialic acids: Using enzymes for biomass conversion. Frontiers in Sialic Acid Research 2016-04-23 - 2016-04-25 2016.

  • Piotrowski, Yvonne; Assefa, Netsanet Gizaw; Helland, Ronny; Johannessen, Kirsti Merete; Willassen, Nils Peder; Larsen, Atle Noralf. Enzymes from the Arctic - The cold gold. BioProsp 2015 2015-02-18 - 2015-02-20 2015.

  • Berg, Tor Olav; Altermark, Bjørn; Leiros, Ingar; Helland, Ronny; Ræder, Inger Lin Uttakleiv. Biocatalytical production of sialic acids and derivatives. Annual BioStruct Conference 2015 2015-08-27 - 2015-08-30 2015.

  • Piotrowski, Yvonne; Assefa, Netsanet Gizaw; Helland, Ronny; Johannessen, Kirsti Merete; Landfald, Bjarne; Smalås, Arne O.; Jørgensen, Trond Ø.; Willassen, Nils Peder; Larsen, Atle Noralf. Enzymes from the Arctic - The cold gold. DNA polymerases: Biology, Diseases and Biomedical Applications 2014-08-31 - 2014-09-04 2014.

  • Forsberg, Zarah; Mackenzie, Alasdair; Sørlie, Morten; Røhr, Åsmund Kjendseth; Helland, Ronny; Vaaje-Kolstad, Gustav; Eijsink, Vincent. Characterization of cellulose-active lytic polysaccharide monooxygenases with complementary activities. Biokjemisk Kontaktmøte 2014 2014-01-23 - 2014-01-26 2014.

  • Ræder, Inger Lin Uttakleiv; Altermark, Bjørn; Gurung, Man Kumari; Helland, Ronny; Smalås, Arne O.. Sialic acids in marine bacteria. Microbial Glycobiology 2014-06-08 - 2014-06-13 2014.

  • Gurung, Man Kumari; Altermark, Bjørn; Ræder, Inger Lin Uttakleiv; Helland, Ronny; Smalås, Arne O.. Features and structure of a sialic acid aldolase from Aliivibrio salmonicida. BIOPROSP 2013 2013-02-20 - 2013-02-22 2013.

  • Ræder, Inger Lin Uttakleiv; Gurung, Man Kumari; Altermark, Bjørn; Berg, Tor Olav; Helland, Ronny; Smalås, Arne O.. Sialic acid biosynthesis in marine bacteria. BIOPROSP 2013 2013-02-20 - 2013-02-22 2013.

  • Olsen, Odd-Arne; Johansen, Wenche; Emilsen, Sidsel; Belova, Tatiana; Liang, Zhe; Smalås, Arne; Johnson, Ken; Helland, Ronny; Schrøder Leiros, Hanna-Kirsti; Jakobsen, Kjetill S.; Shalchian-Tabrizi, Kamran; Quatrano, Ralph; Cove, David; Perroud, Pierre-Francois; Dutcher, Susan; Wilson, Robert; Wilson, Robert. Structural & functional significance of the DEK1 phytocalpain during land plant evolution from green algae. NBS kontaktmøte 2010-01-14 - 2010-01-17 2010.

  • Larsen, Atle Noralf; Helland, Ronny; Svineng, Gunbjørg; Jørgensen, Trond Ø.. Identification, cloning and recombinant expression of a goose-type lysozyme from Atlantic cod (Gadus Morhua). The 7th Nordic symposium on Fish Immunology 2007-06-18 - 2007-06-22 2007.

  • Altermark, Bjørn; Helland, Ronny; Niiranen, Laila Mirja; Moe, Elin; Brandsdal, Bjørn Olav; Smalås, Arne Oskar; Willassen, Nils Peder. Optimum enzymatic activity of endonuclease I from Vibrio salmonicida and Vibrio cholerae correlateswith the bacterial growth habitat. BIOPROSP 2006 2006-10-11 - 2006-10-12 2006.

  • Adekoya, Olayiwola Adedotun; Helland, Ronny; Willassen, Nils Peder; Sylte, Ingebrigt. Structural determinants for a cold adapted enzyme in the thermolysin family. The Norwegian Biochemical Society 41st Contact meeting 2005-01-13 - 2005-01-16 2005.

  • Helland, Ronny; Larsen, Atle Noralf; Willassen, Nils Peder. Structural basis for substrate specificity in two enzymes in the Proteinase K family. 1st ESF and MAX-INF2 Course on Membrane Proteins. The rocky road from gene to structure. Oeiras, Portugal 2005-09-19 - 2005-09-25 2005.

  • Larsen, Atle Noralf; Helland, Ronny; Gjellesvik, Dag Rune; Willassen, Nils Peder. Structural basis for S1-S4 specificity in two enzymes of the proteinase K family. Bioprosp 2004 2004-10-13 - 2004-10-14 2004.

  • Mekonnen, Seble Merid; Olufsen, Magne; Helland, Ronny; Brandsdal, Bjørn Olav; Willassen, Nils Peder; Smalås, Arne Oskar. Residue determinants for substrate specificity from computational analysis and modeling of protein-inhibitor complexes of the subfamily S8A subtilisin-like family of serine proteinases. The 4th European Work Shop in Drug Design (4EWDD) 2003-05-25 - 2003-06-01 2003.

  • Heikinheimo, Pirkko a; Helland, Ronny; Leiros, Hanna-Kirsti S.; Leiros, Ingar; Karlsen, Solveig; Evjen, gry; Ravelli, Raimond; Schoehn, Guy; Ruigrok, Rob; Tollersrud, ole kristian; McSweeney, Sean; Hough, Edward. Structure of the Bovine Lysosomal a-Mannosidase, the Enzyme Involved in the Lysosomal Storage Disease a-Mannosidosis. ESRF Highlights 2002 2003.s 12 - 13.

  • Helland, Ronny. Bioinformatics in Tromsø. Bioinformatics Forum for Young Scientists 2003-03-24 - 2003.

  • Helland, Ronny; Czapinska, Honorata; Otlewski, Jacek; Willassen, Nils Peder; Smalås, Arne Oskar. Primary and secondary specificity of serine proteinases of the chymotrypsin family. Strategies in Macromolecular Structure Determination at 3rd Generation Synchrotron Sources (EMBO practical course) 2003-06-17 - 2003.

  • Heikinheimo, Pirkko a; Helland, Ronny; Frostad, Hilde Monica RS; Hansen, Gaute; Evjen, Gry; Berg, Thomas; Michalski, J C; McSweeney, Sean; Nilssen, Øivind; Tollersrud, Ole Kristian; Hough, Edward. Structural and Functional Characterisation of mutations causing lysosomal a-mannosidosis. 21st European Crystallographic Meeting 2003-08-24 - 2003-08-29 2003.

  • Helland, Ronny; Adekoya, Olayiwola; Mekonnen, Seble Merid; Gjellesvik, Dag Rune; Edvardsen, Øyvind; Høgda, Kjell Arild; Grøttum, Karl Johan; Sylte, Ingebrigt; Smalås, Arne Oskar; Willassen, Nils Peder. Determination of Molecular Descriptors from Analysis of Sequence and Genome Data. Bioinformatics 2002 2002-04-04 - 2002-04-07 2002.

  • Helland, Ronny; Adekoya, Olayiwola; Mekonnen, Seble Merid; Gjellesvik, Dag Rune; Edvardsen, Øyvind; Høgda, Kjell Arild; Grøttum, Karl Johan; Sylte, Ingebrigt; Smalås, Arne Oskar; Willassen, Nils Peder. Determination of Molecular Descriptors from Analysis of Sequence and Genome Data. Functional Genomics in Tromsø 2001-10-17 - 2001-10-18 2001.

  • Helland, Ronny. Structural basis for primary and secondary specificity of serine proteinases. Brukermøte norsk synkrotronforskning 2001-02-18 - 2001-02-19 2001.

  • Smalås, Arne Oskar; Helland, Ronny; Otlewski, J.; Sundheim, O.; Dadlez, M.. The crystal structures of the complexes between bovine -trypsin and ten P1 variants of BPTI. XVIII Congress and general Assembly 1999-08-04 - 1999-08-13 1999.

  • Brandsdal, Bjørn Olav; Helland, Ronny; Sylte, Ingebrigt; Otlewski, J.; Smalås, Arne Oskar. Protein-protein recognition. Talking Proteins: An EMBO workhsop on sequence analysis, modelling and simulation 1998-09-01 - 1998.

  • Helland, Ronny. Crystal Structures of Trypsins in Complex with Inhibitors from Squash Seeds. 3rd Costal Biotechnology Symposium/UiTø 19th Biotechnology Center Meeting 10.09.97, og Norsk Kjemisk Selskaps landsmøte 9.-10. oktober 1997. 1997-01-01 - 1997-01-01 1996.

  • Helland, Ronny; Berglund, Gunnar; Hansen, Lars Kr; Heimstad, Eldbjørg S.; Hordvik, Asbjørn; Leiros, Ingar; Leiros, Hanna-Kirsti S.; Os, vibeke; Outzen, Heidi; Willassen, Nils Peder; Smalås, Arne Oskar. Structure-Function Relation Studies of Enzymes from Cold Adapted Species. Higher European Research Course for Users of Large Experimental Systems (HERCULES) 1995-02-26 - 1995-04-07 1995.

  • Gurung, Man Kumari; Berg, Tor Olav; Halsør, Marie-Josée Haglund; Altermark, Bjørn; Leiros, Ingar; Helland, Ronny; Rothweiler, Ulli; Smalås, Arne O.; Ræder, Inger Lin Uttakleiv. Efficient production of sialic acids- Using enzymes for biomass conversion. Eurocarb 2017 2017-07-02 - 2017-07-06 2017.

  • Gurung, Man Kumari; Berg, Tor Olav; Halsør, Marie-Josée Haglund; Altermark, Bjørn; Leiros, Ingar; Helland, Ronny; Rothweiler, Ulli; Smalås, Arne O.; Ræder, Inger Lin Uttakleiv. Efficient production of sialic acids- Using enzymes for biomass conversion. BIOPROSP2017 2017-03-08 - 2017-03-10 2017.

  • Berg, Tor Olav; Altermark, Bjørn; Leiros, Ingar; Helland, Ronny; Ræder, Inger Lin Uttakleiv. Production of sialic acids and derivatives by enzyme catalysis. NBS Contact meeting 2016 2016-01-21 - 2016-01-23 2016.

  • Berg, Tor Olav; Halsør, Marie-Josée Haglund; Gurung, Man Kumari; Altermark, Bjørn; Leiros, Ingar; Rothweiler, Ulli; Helland, Ronny; Smalås, Arne O.; Ræder, Inger Lin Uttakleiv. From marine rest raw materials to sialic acids: Using enzymes for biomass conversion. Frontiers in Sialic Acid Research 2016-04-23 - 2016-04-25 2016.

  • Piotrowski, Yvonne; Assefa, Netsanet Gizaw; Helland, Ronny; Johannessen, Kirsti Merete; Willassen, Nils Peder; Larsen, Atle Noralf. Enzymes from the Arctic - The cold gold. BioProsp 2015 2015-02-18 - 2015-02-20 2015.

  • Berg, Tor Olav; Altermark, Bjørn; Leiros, Ingar; Helland, Ronny; Ræder, Inger Lin Uttakleiv. Biocatalytical production of sialic acids and derivatives. Annual BioStruct Conference 2015 2015-08-27 - 2015-08-30 2015.

  • Piotrowski, Yvonne; Assefa, Netsanet Gizaw; Helland, Ronny; Johannessen, Kirsti Merete; Landfald, Bjarne; Smalås, Arne O.; Jørgensen, Trond Ø.; Willassen, Nils Peder; Larsen, Atle Noralf. Enzymes from the Arctic - The cold gold. DNA polymerases: Biology, Diseases and Biomedical Applications 2014-08-31 - 2014-09-04 2014.

  • Forsberg, Zarah; Mackenzie, Alasdair; Sørlie, Morten; Røhr, Åsmund Kjendseth; Helland, Ronny; Vaaje-Kolstad, Gustav; Eijsink, Vincent. Characterization of cellulose-active lytic polysaccharide monooxygenases with complementary activities. Biokjemisk Kontaktmøte 2014 2014-01-23 - 2014-01-26 2014.

  • Ræder, Inger Lin Uttakleiv; Altermark, Bjørn; Gurung, Man Kumari; Helland, Ronny; Smalås, Arne O.. Sialic acids in marine bacteria. Microbial Glycobiology 2014-06-08 - 2014-06-13 2014.

  • Gurung, Man Kumari; Altermark, Bjørn; Ræder, Inger Lin Uttakleiv; Helland, Ronny; Smalås, Arne O.. Features and structure of a sialic acid aldolase from Aliivibrio salmonicida. BIOPROSP 2013 2013-02-20 - 2013-02-22 2013.

  • Ræder, Inger Lin Uttakleiv; Gurung, Man Kumari; Altermark, Bjørn; Berg, Tor Olav; Helland, Ronny; Smalås, Arne O.. Sialic acid biosynthesis in marine bacteria. BIOPROSP 2013 2013-02-20 - 2013-02-22 2013.

  • Olsen, Odd-Arne; Johansen, Wenche; Emilsen, Sidsel; Belova, Tatiana; Liang, Zhe; Smalås, Arne; Johnson, Ken; Helland, Ronny; Schrøder Leiros, Hanna-Kirsti; Jakobsen, Kjetill S.; Shalchian-Tabrizi, Kamran; Quatrano, Ralph; Cove, David; Perroud, Pierre-Francois; Dutcher, Susan; Wilson, Robert; Wilson, Robert. Structural & functional significance of the DEK1 phytocalpain during land plant evolution from green algae. NBS kontaktmøte 2010-01-14 - 2010-01-17 2010.

  • Larsen, Atle Noralf; Helland, Ronny; Svineng, Gunbjørg; Jørgensen, Trond Ø.. Identification, cloning and recombinant expression of a goose-type lysozyme from Atlantic cod (Gadus Morhua). The 7th Nordic symposium on Fish Immunology 2007-06-18 - 2007-06-22 2007.

  • Altermark, Bjørn; Helland, Ronny; Niiranen, Laila Mirja; Moe, Elin; Brandsdal, Bjørn Olav; Smalås, Arne Oskar; Willassen, Nils Peder. Optimum enzymatic activity of endonuclease I from Vibrio salmonicida and Vibrio cholerae correlateswith the bacterial growth habitat. BIOPROSP 2006 2006-10-11 - 2006-10-12 2006.

  • Adekoya, Olayiwola Adedotun; Helland, Ronny; Willassen, Nils Peder; Sylte, Ingebrigt. Structural determinants for a cold adapted enzyme in the thermolysin family. The Norwegian Biochemical Society 41st Contact meeting 2005-01-13 - 2005-01-16 2005.

  • Helland, Ronny; Larsen, Atle Noralf; Willassen, Nils Peder. Structural basis for substrate specificity in two enzymes in the Proteinase K family. 1st ESF and MAX-INF2 Course on Membrane Proteins. The rocky road from gene to structure. Oeiras, Portugal 2005-09-19 - 2005-09-25 2005.

  • Larsen, Atle Noralf; Helland, Ronny; Gjellesvik, Dag Rune; Willassen, Nils Peder. Structural basis for S1-S4 specificity in two enzymes of the proteinase K family. Bioprosp 2004 2004-10-13 - 2004-10-14 2004.

  • Mekonnen, Seble Merid; Olufsen, Magne; Helland, Ronny; Brandsdal, Bjørn Olav; Willassen, Nils Peder; Smalås, Arne Oskar. Residue determinants for substrate specificity from computational analysis and modeling of protein-inhibitor complexes of the subfamily S8A subtilisin-like family of serine proteinases. The 4th European Work Shop in Drug Design (4EWDD) 2003-05-25 - 2003-06-01 2003.

  • Heikinheimo, Pirkko a; Helland, Ronny; Leiros, Hanna-Kirsti S.; Leiros, Ingar; Karlsen, Solveig; Evjen, gry; Ravelli, Raimond; Schoehn, Guy; Ruigrok, Rob; Tollersrud, ole kristian; McSweeney, Sean; Hough, Edward. Structure of the Bovine Lysosomal a-Mannosidase, the Enzyme Involved in the Lysosomal Storage Disease a-Mannosidosis. ESRF Highlights 2002 2003.s 12 - 13.

  • Helland, Ronny. Bioinformatics in Tromsø. Bioinformatics Forum for Young Scientists 2003-03-24 - 2003.

  • Helland, Ronny; Czapinska, Honorata; Otlewski, Jacek; Willassen, Nils Peder; Smalås, Arne Oskar. Primary and secondary specificity of serine proteinases of the chymotrypsin family. Strategies in Macromolecular Structure Determination at 3rd Generation Synchrotron Sources (EMBO practical course) 2003-06-17 - 2003.

  • Heikinheimo, Pirkko a; Helland, Ronny; Frostad, Hilde Monica RS; Hansen, Gaute; Evjen, Gry; Berg, Thomas; Michalski, J C; McSweeney, Sean; Nilssen, Øivind; Tollersrud, Ole Kristian; Hough, Edward. Structural and Functional Characterisation of mutations causing lysosomal a-mannosidosis. 21st European Crystallographic Meeting 2003-08-24 - 2003-08-29 2003.

  • Helland, Ronny; Adekoya, Olayiwola; Mekonnen, Seble Merid; Gjellesvik, Dag Rune; Edvardsen, Øyvind; Høgda, Kjell Arild; Grøttum, Karl Johan; Sylte, Ingebrigt; Smalås, Arne Oskar; Willassen, Nils Peder. Determination of Molecular Descriptors from Analysis of Sequence and Genome Data. Bioinformatics 2002 2002-04-04 - 2002-04-07 2002.

  • Helland, Ronny; Adekoya, Olayiwola; Mekonnen, Seble Merid; Gjellesvik, Dag Rune; Edvardsen, Øyvind; Høgda, Kjell Arild; Grøttum, Karl Johan; Sylte, Ingebrigt; Smalås, Arne Oskar; Willassen, Nils Peder. Determination of Molecular Descriptors from Analysis of Sequence and Genome Data. Functional Genomics in Tromsø 2001-10-17 - 2001-10-18 2001.

  • Helland, Ronny. Structural basis for primary and secondary specificity of serine proteinases. Brukermøte norsk synkrotronforskning 2001-02-18 - 2001-02-19 2001.

  • Smalås, Arne Oskar; Helland, Ronny; Otlewski, J.; Sundheim, O.; Dadlez, M.. The crystal structures of the complexes between bovine -trypsin and ten P1 variants of BPTI. XVIII Congress and general Assembly 1999-08-04 - 1999-08-13 1999.

  • Brandsdal, Bjørn Olav; Helland, Ronny; Sylte, Ingebrigt; Otlewski, J.; Smalås, Arne Oskar. Protein-protein recognition. Talking Proteins: An EMBO workhsop on sequence analysis, modelling and simulation 1998-09-01 - 1998.

  • Helland, Ronny. Crystal Structures of Trypsins in Complex with Inhibitors from Squash Seeds. 3rd Costal Biotechnology Symposium/UiTø 19th Biotechnology Center Meeting 10.09.97, og Norsk Kjemisk Selskaps landsmøte 9.-10. oktober 1997. 1997-01-01 - 1997-01-01 1996.

  • Helland, Ronny; Berglund, Gunnar; Hansen, Lars Kr; Heimstad, Eldbjørg S.; Hordvik, Asbjørn; Leiros, Ingar; Leiros, Hanna-Kirsti S.; Os, vibeke; Outzen, Heidi; Willassen, Nils Peder; Smalås, Arne Oskar. Structure-Function Relation Studies of Enzymes from Cold Adapted Species. Higher European Research Course for Users of Large Experimental Systems (HERCULES) 1995-02-26 - 1995-04-07 1995.

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