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Bilde av Hansen, Espen Holst
Bilde av Hansen, Espen Holst
The Norwegian College of Fishery Science espen.hansen@uit.no +4777649262 Tromsø FPARK A 206

Espen Holst Hansen

Reseracher, Marbio.

Job description

Professor in marine biotechnology

Deputy head of research, Norwegian College of Fishery Sciences (NCFS)

  • Yannik Karl Heinz Schneider, Anton Liaimer, Johan Mattias Isaksson, Oda Sofie Bye Wilhelmsen, Jeanette Hammer Andersen, Kine Østnes Hansen et al.:
    Four new suomilides isolated from the cyanobacterium Nostoc sp. KVJ20 and proposal of their biosynthetic origin
    Frontiers in Microbiology 2023 ARKIV / DOI
  • Yannik Karl Heinz Schneider, Ole Christian Hagestad, Chun Li, Espen Holst Hansen, Jeanette Hammer Andersen :
    Selective isolation of Arctic marine actinobacteria and a down-scaled fermentation and extraction strategy for identifying bioactive compounds
    Frontiers in Microbiology 21. October 2022 ARKIV / DOI
  • Giovanna Romano, Mariana Almeida, Ana Varela Coelho, Adele Cutignano, Lous G Goncalves, Espen Holst Hansen et al.:
    Biomaterials and Bioactive Natural Products from Marine Invertebrates: From Basic Research to Innovative Applications
    Marine Drugs 2022 ARKIV / DOI
  • Hans Christian Eilertsen, Gunilla Eriksen, John-Steinar Bergum, Jo Strømholt, Edel O. Elvevoll, Karl-Erik Eilertsen et al.:
    Mass Cultivation of Microalgae: I. Experiences with Vertical Column Airlift Photobioreactors, Diatoms and CO2 Sequestration
    Applied Sciences 2022 ARKIV / DOI
  • Fazlin Pheiffer, Yannik Karl Heinz Schneider, Espen Holst Hansen, Jeanette Hammer Andersen, Johan Mattias Isaksson, Tobias Busche et al.:
    Bioassay-Guided Fractionation Leads to the Detection of Cholic Acid Generated by the Rare Thalassomonas sp.
    Marine Drugs 2022 ARKIV / DOI
  • Hans Christian Eilertsen, Edel O. Elvevoll, Ingeborg Hulda Giæver, Jon Brage Svenning, Lars Dalheim, Ragnhild Aven Svalheim et al.:
    Inclusion of photoautotrophic cultivated diatom biomass in salmon feed can deter lice
    PLOS ONE 29. July 2021 ARKIV / DOI
  • Yannik Karl-Heinz Schneider, Solveig Jørgensen, Jeanette Hammer Andersen, Espen Hansen :
    Qualitative and quantitative comparison of liquid–liquid phase extraction using ethyl acetate and liquid–solid phase extraction using poly-benzyl-resin for natural products
    Applied Sciences 2021 ARKIV / DOI
  • Kine Østnes Hansen, Ida Kristine Østnes Hansen, Céline Sarah Marine Richard, Marte Jenssen, Jeanette Hammer Andersen, Espen Holst Hansen :
    Antimicrobial Activity of Securamines From the Bryozoan Securiflustra securifrons
    Natural Product Communications 2021 ARKIV / DOI
  • Renate Døving Osvik, Jeanette Hammer Andersen, Hans Christian Eilertsen, Anne-Marie Genevière, Espen Holst Hansen :
    Bioactivity of a Marine Diatom (Porosira glacialis [Grunow] Jorgensen 1905) Cultivated With and Without Factory Smoke CO2
    Industrial Biotechnology 2021 ARKIV / DOI
  • Renate Døving Osvik, Richard Andre Ingebrigtsen, Fredrika Norrbin, Jeanette Hammer Andersen, Hans Christian Eilertsen, Espen Holst Hansen :
    Adding zooplankton to the OSMAC toolkit: Effect of grazing stress on the metabolic profile and bioactivity of a diatom
    Marine Drugs 2021 ARKIV / DOI
  • Venke Kristoffersen, Marte Jenssen, Heba Raid Jawad, Johan Isaksson, Espen Hansen, Teppo Rämä et al.:
    Two Novel Lyso-Ornithine Lipids Isolated from an Arctic Marine Lacinutrix sp. Bacterium
    Molecules 2021 ARKIV / DOI
  • Marte Jenssen, Venke Kristoffersen, Kumar Motiram-Corral, Johan Isaksson, Teppo Rämä, Jeanette Hammer Andersen et al.:
    Chlovalicin B, a Chlorinated Sesquiterpene Isolated from the Marine Mushroom Digitatispora marina
    Molecules 2021 ARKIV / DOI
  • Ole Christian Hagestad, Lingwei Hou, Jeanette Hammer Andersen, Espen Hansen, Bjørn Altermark, Chun Li et al.:
    Genomic characterization of three marine fungi, including Emericellopsis atlantica sp. nov. with signatures of a generalist lifestyle and marine biomass degradation
    IMA Fungus 2021 ARKIV / DOI
  • Marte Jenssen, Philip Rainsford, Eric Juskewitz, Jeanette Hammer Andersen, Espen Hansen, Johan Isaksson et al.:
    Lulworthinone, a New Dimeric Naphthopyrone From a Marine Fungus in the Family Lulworthiaceae With Antibacterial Activity Against Clinical Methicillin-Resistant Staphylococcus aureus Isolates
    Frontiers in Microbiology 2021 ARKIV / DOI
  • Jørgen A Mølmann, Espen Holst Hansen, Tor Jacob Johansen :
    Effects of supplemental LED light quality and reduced growth temperature on swede (Brassica napus L. ssp. rapifera Metzg.) root vegetable development and contents of glucosinolates and sugars
    Journal of the Science of Food and Agriculture 2020 ARKIV / DOI
  • Yannik Karl-Heinz Schneider, Marte Jenssen, Johan Isaksson, Kine Østnes Hansen, Jeanette Hammer Andersen, Espen Hansen :
    Bioactivity of Serratiochelin A, a Siderophore Isolated from a Co-Culture of Serratia sp. and Shewanella sp.
    Microorganisms 14. July 2020 ARKIV / DOI
  • Chiara Lauritano, Kirsti Helland, Gennaro Riccio, Jeanette Hammer Andersen, Adrianna Ianora, Espen Holst Hansen :
    Lysophosphatidylcholines and Chlorophyll-Derived Molecules from the Diatom Cylindrotheca closterium with Anti-Inflammatory Activity
    Marine Drugs 17. March 2020 ARKIV / DOI
  • Philip Brennecke, Dace Rasina, Oscar Aubi Catevilla, Katja Herzog, Johannes Landskron, Bastien Cautain et al.:
    EU-OPENSCREEN: A novel collaborative approach to facilitate chemical biology
    SLAS Discovery 2019 ARKIV / DOI
  • Yannik Karl-Heinz Schneider, Kine Østnes Hansen, Johan Isaksson, Sara Maria Ullsten-Wahlund, Espen Hansen, Jeanette Hammer Andersen :
    Anti-Bacterial Effect and Cytotoxicity Assessment of Lipid 430 Isolated from Algibacter sp.
    Molecules 2019 ARKIV / DOI
  • Kine Østnes Hansen, Jeanette hammer Andersen, Annette Bayer, Sunil Kumar Pandey, Marianne Lorentzen, Kåre Bredeli Jørgensen et al.:
    Kinase chemodiversity from the Arctic: the breitfussins
    Journal of Medicinal Chemistry 2019 ARKIV / DOI
  • Ole Christian Hagestad, Jeanette hammer Andersen, Bjørn Altermark, Espen Hansen, Teppo Rämä :
    Cultivable marine fungi from the Arctic Archipelago of Svalbard and their antibacterial activity
    Mycology: An International Journal on Fungal Biology 2019 ARKIV / DOI
  • Raja Priyanka Mary Michael Siranjeevi, Espen Hansen, Johan Isaksson, Jeanette hammer Andersen, Kine Østnes Hansen :
    Dendrobeaniamine A, a new alkaloid from the Arctic marine bryozoan Dendrobeania murrayana
    Natural Product Research 2019 ARKIV / DOI
  • Kine Østnes Hanssen, Johan Isaksson, Eirin Glomsaker, Jeanette hammer Andersen, Espen Hansen :
    Ponasterone A and F, Ecdysteroids from the Arctic Bryozoan Alcyonidium gelatinosum
    Molecules 2018 ARKIV / DOI
  • Anne Linn Hykkerud, Eivind Uleberg, Espen Hansen, Marieke Vervoort, Jørgen Mølmann, Inger Martinussen :
    Seasonal and yearly variation of total polyphenols, total anthocyanins and ellagic acid in different clones of cloudberry (Rubus chamaemorus L.)
    Angewandte Botanik 2018 ARKIV / DOI
  • Venke Kristoffersen, Teppo Rämä, Johan Isaksson, Jeanette hammer Andersen, William H. Gerwick, Espen Hansen :
    Characterization of Rhamnolipids Produced by an Arctic Marine Bacterium from the Pseudomonas fluorescence Group
    Marine Drugs 2018 ARKIV / DOI
  • Richard Andre Ingebrigtsen, Espen Hansen, Jeanette hammer Andersen, Hans Christian Eilertsen :
    Field sampling marine plankton for biodiscovery
    Scientific Reports 2017 ARKIV / DOI
  • Marit Huizer, Kristine Haugland, Agnethe Hansen Bæverud, Jon Brage Svenning, Kine Østnes Hansen, Espen Holst Hansen et al.:
    LC-Orbitrap MS/MS based untargeted lipidomics of marine microalgae
    2023
  • Magnus Andersland Antonsen, Kine Østnes Hansen, Espen Holst Hansen, Terje Vasskog :
    Use of metabolomics to identify secondary metabolites from marine algae biomass
    2023
  • Guillaume Petit, Kine Østnes Hansen, Jeanette Hammer Andersen, Espen Holst Hansen, Annette Bayer, Bengt Erik Haug et al.:
    A fragment to bind them all: Characterising phorbazole fragments as pan-kinase inhibitor
    2023
  • Espen Holst Hansen, Kine Østnes Hansen, Jeanette Hammer Andersen :
    HotBio - a Horizon Europe MSCA Doctoral Network in Marine Biodiscovery
    2023
  • Espen Holst Hansen :
    Discovery of new antibacterial compounds from the Arctic Ocean
    2023
  • Espen Holst Hansen :
    Marbio - A platform for marine natural products drug discovery
    2021
  • Yannik Karl-Heinz Schneider, Njål Rauø, Espen Holst Hansen, Jeanette Hammer Andersen, Jascha MacDonald, Wolfgang R. Streit et al.:
    The SuReMetS-project - From sustainable resources to novel marine nutraceuticals for the management of metabolic syndrome
    2021
  • Espen Holst Hansen, Jeanette hammer Andersen :
    Molekylet som kan stoppe brystkreft
    07. January 2020
  • Anette Hustad, Birthe Vang, Hans Christian Eilertsen, Sten Ivar Siikavuopio, Bjørn-Steinar Sæther, Ragnhild Aven Svalheim et al.:
    Mikroalger i fôr, ny løsning for å redusere lusepåslag på laks – Faglig sluttrapport
    2020 FULLTEKST / ARKIV
  • Espen Holst Hansen, Kine Østnes Hansen, Jeanette hammer Andersen :
    Nye legemidler fra havet?
    Dagens næringsliv 04. January 2020 FULLTEKST
  • Espen Hansen :
    Natural Product Drug Discovery From Marine Organisms With Advanced UPLC and MS Technology
    2019 FULLTEKST
  • Espen Hansen :
    Novel kinase inhibitors from the Arctic marine hydrozoan Thuiaria breitfussi
    2019
  • Kine Ø. Hanssen, Jeanette hammer Andersen, Bert Klebl, Jan Eickhoff, Johan Isaksson, Espen Hansen :
    Novel kinase inhibitors from the Arctic marine hydrozoan Thuiaria breitfussi
    2019
  • Marte Jenssen, Teppo Rämä, Kine Ø. Hanssen, Venke Kristoffersen, Espen Hansen, Jeanette hammer Andersen :
    Exploring the chemical and biological potential of Arctic marine fungi
    2019
  • Espen Hansen :
    Cutting-Edge Analytical Technology Advances Arctic Marine Bioprospecting
    06. March 2019
  • Espen Hansen :
    Good prospects
    European Laboratory Technology 2019 FULLTEKST
  • Espen Hansen :
    Use of ion mobility in mass spectrometry-based metabolomics of marine natural products
    2019
  • Renate Døving Osvik, Espen Hansen, Hans Christian Eilertsen, Anne-Marie Genevière :
    Extract of a marine diatom negatively affects development in sea urchin (Paracentrotus lividus) embryos
    2019
  • Yannik Karl-Heinz Schneider, Espen Hansen :
    Quantitative comparison of solid and liquid phase extraction of natural products from bacterial fermentations
    2019
  • Priyanka Michael, Espen Hansen, Johan Isaksson, Jeanette hammer Andersen, Kine Østnes Hansen :
    Dendrobeaniamine A, a New Alkaloid from the Arctic Marine bryozoan Dendrobeania murrayana
    2019
  • Marte Jenssen, Jeanette Hammer Andersen, Teppo Rämä, Espen Holst Hansen, Kine Østnes Hansen, Chun Li :
    Biodiscovery of Antimicrobial Compounds from Arctic Marine Microorganisms
    2019
  • Espen Hansen :
    Marine bioprospecting - The search for bioactive compounds of scientific and commercial interest in the marine environment
    2019
  • Ole Christian Hagestad, Teppo Rämä, Bjørn Altermark, Espen Hansen, Jeanette hammer Andersen :
    Exploring the diversity and bioactivity of cultivable Arctic marine fungi from the Svalbard archipelago
    2018
  • Ole Christian Hagestad, Teppo Rämä, Bjørn Altermark, Espen Hansen, Jeanette hammer Andersen :
    Diversity and antibacterial properties of marine fungi from the Arctic Ocean
    2017

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    Research interests

    I am responsible for the chemical characterisation of bioactive secondary metabolites in Marbio.

    The tools I use in the laboratory includes:

    • Mass spectrometry (MS), both quadropoles and high-resolution (HR) systems
    • Ion mobility spectrometry (IMS)
    • Chromatography, including low pressure (Flash) as well as both HPLC and UHPLC

    I use these tools to isolate and characterize bioactive secondary metabolites through the following workflows:

    • Extraction and prefractionation of biological material
    • Dereplication of bioactive extracts and fractions using UHPLC-IMS-HR-MS
    • Metabolic profiling and metabolomics
    • Mass guided fractionation using HPLC
    ORCID: 0000-0003-0354-986X

    Member of research group

    Marbio – an analytical platform for natural products   Norsk innhold
    FPARK A 206

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