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Associate Professor

Jorunn Pauline Cavanagh

Associate Professor at Paediatric Infection Group Department of Clinical Medicine
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My field of research is on infections caused by coagulase negative staphylococci (CoNS), predominantly affecting immunocompromised individuals and premature babies. Clinical CoNS are good biofilm producers and often multiresistant, our main research aim is to identify new targets for treatment.
I am also involved in research on gut microbiome changes in health and disease.

I am employed as Associate Professor at Pediatric Infection group. I am supervising master and PhD students.

  • Wolden, Runa; Pain, Maria; Karlsson, Roger; Karlsson, Anders; Fredheim, Elizabeth G. Aarag; Cavanagh, Jorunn Pauline. Identification of surface proteins in a clinical Staphylococcus haemolyticus isolate by bacterial surface shaving. BMC Microbiology 2020; Volum 20:80. ISSN 1471-2180.s 1 - 18.s doi: 10.1186/s12866-020-01778-8.

  • Ronessen Pain, Maria; Wolden, Runa; Jaén-Luchoro, Daniel; Salvà-Serra, Francisco; Iglesias, Beatriz Piñeiro; Karlsson, Roger; Klingenberg, Claus; Cavanagh, Jorunn Pauline. Staphylococcus borealis sp. Nov., isolated from human skin and blood. International Journal of Systematic and Evolutionary Microbiology 2020; Volum 70 (12). ISSN 1466-5026.s 6067 - 6068.s doi: 10.1099/ijsem.0.004499.

  • Vimberg, Vladimir; Cavanagh, Jorunn Pauline; Novotna, Michaela; Lenart, Jakub; Nguyen Thi Ngoc, Bich; Vesela, Jana; Ronessen Pain, Maria; Koberska, Marketa; Balikova Novotna, Gabriela. Ribosome-Mediated Attenuation of vga(A) Expression Is Shaped by the Antibiotic Resistance Specificity of Vga(A) Protein Variants. Antimicrobial Agents and Chemotherapy 2020; Volum 64 (11). ISSN 0066-4804.s doi: 10.1128/AAC.00666-20.

  • Goll, Rasmus; Johnsen, Peter Holger; Hjerde, Erik; Diab, Joseph; Valle, Per Christian; Hilpüsch, Frank; Cavanagh, Jorunn Pauline. Effects of fecal microbiota transplantation in subjects with irritable bowel syndrome are mirrored by changes in gut microbiome. Gut microbes 2020; Volum 12:e1794263 (1). ISSN 1949-0976.s 1 - 15.s doi: 10.1080/19490976.2020.1794263.

  • Cavanagh, Jorunn Pauline; Askarian, Fatemeh; Pain, Maria; Bruun, Jack-Ansgar; Urbarova, Ilona; Wai, Sun Nyunt; Schmidt, Frank; Johannessen, Mona. Proteome profiling of secreted and membrane vesicle associated proteins of an invasive and a commensal Staphylococcus haemolyticus isolate.. Data in Brief 2019; Volum 22. ISSN 2352-3409.s 914 - 919.s doi: 10.1016/j.dib.2018.11.147.

  • Pain, Maria; Hjerde, Erik; Klingenberg, Claus; Cavanagh, Jorunn Pauline. Comparative Genomic Analysis of Staphylococcus haemolyticus Reveals Key to Hospital Adaptation and Pathogenicity. Frontiers in Microbiology 2019; Volum 10. ISSN 1664-302X.s doi: 10.3389/fmicb.2019.02096.

  • Flygel, Trym Thune; Sovershaeva, Evgeniya; Classen-Weitz, Shantelle; Hjerde, Erik; Mwaikono, Kilaza S.; Odland, Jon Øyvind; Ferrand, Rashida A.; McHugh, Grace; Gutteberg, Tore Jarl; Nicol, Mark P.; Cavanagh, Jorunn Pauline; Flægstad, Trond. Composition of Gut Microbiota of Children and Adolescents With Perinatal Human Immunodeficiency Virus Infection Taking Antiretroviral Therapy in Zimbabwe. Journal of Infectious Diseases 2019. ISSN 0022-1899.s 1 - 10.s doi: 10.1093/infdis/jiz473.

  • Granslo, Hildegunn Norbakken; Aarag, Elizabeth; Esaiassen, Eirin; Christophersen, Lars; Jensen, Peter Østrup; Mollnes, Tom Eirik; Moser, Claus; Flægstad, Trond; Klingenberg, Claus; Cavanagh, Jorunn Pauline. The synthetic antimicrobial peptide LTX21 induces inflammatory responses in a human whole blood model and a murine peritoneum model. APMIS - Journal of Pathologiy, Microbiology and Immunology 2019; Volum 127 (6). ISSN 0903-4641.s 475 - 483.s doi: 10.1111/apm.12946.

  • Vimberg, Vladimir; Cavanagh, Jorunn Pauline; Benada, Oldrich; Kofranova, Olga; Hjerde, Erik; Zieglerova, Leona; Balikova Novotna, Gabriela. Teicoplanin resistance in Staphylococcus haemolyticus is associated with mutations in histidine kinases VraS and WalK. Diagnostic microbiology and infectious disease 2018; Volum 90 (3). ISSN 0732-8893.s 233 - 240.s doi: 10.1016/j.diagmicrobio.2017.11.007.

  • Esaiassen, Eirin; Hjerde, Erik; Cavanagh, Jorunn Pauline; Pedersen, Tanja; Andresen, Jannicke Hanne; Rettedal, Siren; Støen, Ragnhild; Nakstad, Britt; Willassen, Nils Peder; Klingenberg, Claus. Effects of Probiotic Supplementation on the Gut Microbiota and Antibiotic Resistome Development in Preterm Infants. Frontiers in pediatrics 2018; Volum 6 (November 2018). ISSN 2296-2360.s doi: 10.3389/fped.2018.00347.

  • Cavanagh, Jorunn Pauline; Pain, Maria; Askarian, Fatemeh; Bruun, Jack-Ansgar; Urbarova, Ilona; Wai, Sun Nyunt; Schmidt, Frank; Johannessen, Mona. Comparative exoproteome profiling of an invasive and a commensal Staphylococcus haemolyticus isolate. Journal of Proteomics 2018; Volum 18. ISSN 1874-3919.s 1874 - 3919.s doi: 10.1016/j.jprot.2018.11.013.

  • Askarian, Fatemeh; Lapek Jr., John D.; Dongre, Mitesh; Tsai, Chih-Ming; Kumaraswamy, Monika; Kousha, Armin; Valderrama, J. Andrés; Ludviksen, Judith K; Cavanagh, Jorunn Pauline; Uchiyama, Satoshi; Mollnes, Tom Eirik; Gonzalez, David J.; Wai, Sun Nyunt; Victor, Nizet; Johannessen, Mona. Staphylococcus aureus Membrane-derived Vesicles Promote Bacterial Virulence and Confer Protective Immunity in Murine Infection Models. Frontiers in Microbiology 2018; Volum 9. ISSN 1664-302X.s doi: 10.3389/fmicb.2018.00262.

  • Esaiassen, Eirin; Hjerde, Erik; Cavanagh, Jorunn Pauline; Simonsen, Gunnar Skov; Klingenberg, Claus. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. Journal of Clinical Microbiology 2017; Volum 55 (7). ISSN 0095-1137.s 2234 - 2248.s doi: 10.1128/JCM.00150-17.

  • Johnsen, Peter Holger; Hilpüsch, Frank; Cavanagh, Jorunn Pauline; Leikanger, Ingrid Sande; Kolstad, Caroline; Valle, Per Christian; Goll, Rasmus. Faecal microbiota transplantation versus placebo for moderate-to-severe irritable bowel syndrome: a double-blind, randomised, placebo-controlled, parallel-group, single-centre trial. The Lancet Gastroenterology and Hepatology 2017; Volum 3 (1). ISSN 2468-1253.s 17 - 24.s doi: 10.1016/S2468-1253(17)30338-2.

  • de Oliveira, Caio Fernando; Cavanagh, Jorunn Pauline; Aarag, Elizabeth; Reiter, Keli Cristine; Rieger, Alexandre; Klingenberg, Claus; D'Azevedo, Pedro Alves; Sollid, Johanna U Ericson. Coagulase-negative staphylococci in southern brazil: Looking toward its high diversity. Revista da Sociedade Brasileira de Medicina Tropical 2016; Volum 49 (3). ISSN 0037-8682.s 292 - 299.s doi: 10.1590/0037-8682-0015-2016.

  • Cavanagh, Jorunn Pauline; Wolden, Runa; Heise, Philipp; Esaiassen, Eirin; Klingenberg, Claus; Aarag, Elizabeth. Antimicrobial susceptibility and body site distribution of community isolates of coagulase-negative staphylococci. APMIS - Journal of Pathologiy, Microbiology and Immunology 2016; Volum 124 (11). ISSN 0903-4641.s 973 - 978.s doi: 10.1111/apm.12591.

  • Cavanagh, Jorunn Pauline; Hjerde, Erik; Holden, Matthew T.G.; Kahlke, Tim; Klingenberg, Claus; Flægstad, Trond; Parkhill, J; Bentley, Stephen D; Sollid, Johanna U Ericson. Whole-genome sequencing reveals clonal expansion of multiresistant Staphylococcus heamolyticus in European hopsitals. Journal of Antimicrobial Chemotherapy 2014; Volum 69 (11). ISSN 0305-7453.s 2920 - 2927.s doi: 10.1093/jac/dku271.

  • Cavanagh, Jorunn Pauline; Granslo, Hildegunn Norbakken; Aarag, Elizabeth; Christophersen, L; Jensen, Peter Østrup; Thomsen, Kim; Van Gennip, Maria; Klingenberg, Claus; Flægstad, Trond; Moser, Claus. Efficacy of a synthetic antimicrobial peptidomimetic versus vancomycin in a Staphylococcus epidermidis device-related murine peritonitis model. Journal of Antimicrobial Chemotherapy 2013; Volum 68 (9). ISSN 0305-7453.s 2106 - 2110.s doi: 10.1093/jac/dkt161.

  • Cavanagh, Jorunn Pauline; Klingenberg, Claus; Hanssen, Anne-Merethe; Aarag, Elizabeth; Francois, Patrice; Schrenzel, Jaques; Flægstad, Trond; Sollid, Johanna U Ericson. Core genome conservation of Staphylococcus haemolyticus limits sequence based population structure analysis. Journal of Microbiological Methods 2012; Volum 89 (3). ISSN 0167-7012.s 159 - 166.s doi: 10.1016/j.mimet.2012.03.014.

  • Flemming, Kristina; Klingenberg, Claus; Cavanagh, Jorunn Pauline; Sletteng, Merethe vibeke; Stensen, Wenche; Svendsen, John Sigurd; Flaegstad, Trond. High in vitro antimicrobial activity of synthetic antimicrobial peptidomimetics against staphylococcal biofilms. Journal of Antimicrobial Chemotherapy 2009; Volum 63 (1). ISSN 0305-7453.s 136 - 145.s doi: 10.1093/jac/dkn464.

  • Wolden, Runa; Pain, Maria; Karlsson, Roger; Karlsson, Anders; Fredheim, Elizabeth G. Aarag; Cavanagh, Jorunn Pauline. Hunting new targets to prevent infections - A novel approach to bacterial surface shaving. IBA annual meeting 2019-11-04 - 2019-11-05 2019.

  • Wolden, Runa; Pain, Maria; Karlsson, Roger; Karlsson, Anders; Fredheim, Elizabeth G. Aarag; Cavanagh, Jorunn Pauline. På jakt etter nye målsete for behandling av Staphylococcus haemolyticus-infeksjonar: Opp- regulering av sentrale virulens- og adhesjonsprotein hos S. haemolyticus ved kolonisering av humane keratinocyttar. Bioingeniørkongressen 2019-05-22 - 2019-05-24 2019.

  • Bjerkhaug, Aline; Granslo, Hildegunn Norbakken; Cavanagh, Jorunn Pauline; Klingenberg, Claus. JAKTEN PÅ ANTIBIOTIKAENS LILLE HJELPER. (https://www.pingvinavisa.no/jakten-pa-antibiotikaens-lille-hjelper/) Pingvinavisa 2019.

  • Bjerkhaug, Aline; Granslo, Hildegunn Norbakken; Cavanagh, Jorunn Pauline; Mollnes, Tom Eirik; Klingenberg, Claus. The method of combined inhibition of CD14 and C5 in Escherichia coli and Streptococcus agalactiae induced inflammation in human cord blood.. National Graduate School in Infection Biology and Antimicrobials (IBA) - Annual Meeting 2019-11-03 - 2019-11-05 2019.

  • Vimberg, Vladimir; Gažá, Radek; Szűcs, Zsolt; Borbás, Aniko; Herczegh, Pál; Cavanagh, Jorunn Pauline; Zieglerová, Leona; Závora, Jan; Adámková, Václava; Balíková Novotná, Gabriela. Fluorescence assay to predict activity of the glycopeptide antibiotics. Journal of antibiotics (Tokyo. 1968) 2019; Volum 72 (2). ISSN 0021-8820.s 114 - 117.s doi: 10.1038/s41429-018-0120-5.

  • Granslo, Hildegunn Norbakken; Aarag, Elizabeth; Klingenberg, Claus Andreas; Moser, Claus; Esaiassen, Eirin; Cavanagh, Jorunn Pauline; Christophersen, Lars; Mollnes, Tom Eirik; østrup jensen, peter; Flægstad, Trond. The synthetic antimicrobial peptide LTX21 induces inflammatory responses in an in vivo mouse peritonitis model and an ex vivo human whole blood model. Konferanse 2017-09-13 - 2017-09-15 2017.

  • Cavanagh, Jorunn Pauline. Min doktorgrad. "Når snille bakterier blir slemme". Scrødingers katt sin serie: "min dokrorgrad" 2012-03-29 - 2012-03-29 2012.

  • Cavanagh, Jorunn Pauline. Forsker Grand Prix 2011. Forsker Grand Prix 2011 2011-09-28 - 2011-09-28 2011.

  • Wolden, Runa; Pain, Maria; Karlsson, Roger; Karlsson, Anders; Fredheim, Elizabeth G. Aarag; Cavanagh, Jorunn Pauline. Hunting new targets to prevent infections - A novel approach to bacterial surface shaving. IBA annual meeting 2019-11-04 - 2019-11-05 2019.

  • Wolden, Runa; Pain, Maria; Karlsson, Roger; Karlsson, Anders; Fredheim, Elizabeth G. Aarag; Cavanagh, Jorunn Pauline. På jakt etter nye målsete for behandling av Staphylococcus haemolyticus-infeksjonar: Opp- regulering av sentrale virulens- og adhesjonsprotein hos S. haemolyticus ved kolonisering av humane keratinocyttar. Bioingeniørkongressen 2019-05-22 - 2019-05-24 2019.

  • Bjerkhaug, Aline; Granslo, Hildegunn Norbakken; Cavanagh, Jorunn Pauline; Klingenberg, Claus. JAKTEN PÅ ANTIBIOTIKAENS LILLE HJELPER. (https://www.pingvinavisa.no/jakten-pa-antibiotikaens-lille-hjelper/) Pingvinavisa 2019.

  • Bjerkhaug, Aline; Granslo, Hildegunn Norbakken; Cavanagh, Jorunn Pauline; Mollnes, Tom Eirik; Klingenberg, Claus. The method of combined inhibition of CD14 and C5 in Escherichia coli and Streptococcus agalactiae induced inflammation in human cord blood.. National Graduate School in Infection Biology and Antimicrobials (IBA) - Annual Meeting 2019-11-03 - 2019-11-05 2019.

  • Vimberg, Vladimir; Gažá, Radek; Szűcs, Zsolt; Borbás, Aniko; Herczegh, Pál; Cavanagh, Jorunn Pauline; Zieglerová, Leona; Závora, Jan; Adámková, Václava; Balíková Novotná, Gabriela. Fluorescence assay to predict activity of the glycopeptide antibiotics. Journal of antibiotics (Tokyo. 1968) 2019; Volum 72 (2). ISSN 0021-8820.s 114 - 117.s doi: 10.1038/s41429-018-0120-5.

  • Granslo, Hildegunn Norbakken; Aarag, Elizabeth; Klingenberg, Claus Andreas; Moser, Claus; Esaiassen, Eirin; Cavanagh, Jorunn Pauline; Christophersen, Lars; Mollnes, Tom Eirik; østrup jensen, peter; Flægstad, Trond. The synthetic antimicrobial peptide LTX21 induces inflammatory responses in an in vivo mouse peritonitis model and an ex vivo human whole blood model. Konferanse 2017-09-13 - 2017-09-15 2017.

  • Cavanagh, Jorunn Pauline. Min doktorgrad. "Når snille bakterier blir slemme". Scrødingers katt sin serie: "min dokrorgrad" 2012-03-29 - 2012-03-29 2012.

  • Cavanagh, Jorunn Pauline. Forsker Grand Prix 2011. Forsker Grand Prix 2011 2011-09-28 - 2011-09-28 2011.


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