Family history of myocardial infarction increases your risk of Venous Thrombosis

Family history of myocardial infarction share yet unknown inherited or environmental risk factors of venous thrombosis

We investigated 21 624 subjects from the Tromsø Study and found that subjects with a first-degree relative with a history of myocardial infarction had 52 % increased risk of myocardial infarction and 26 % increased risk of venous thrombosis compared to those without a family history of myocardial infarction.

The association between family history of myocardial infarction and venous thrombosis was not explained by risk factors for atherosclerosis or a direct effect of myocardial infarction on the risk of venous thrombosis, and was primarily related to unprovoked deep vein thrombosis.

Our findings support the concept that subjects with a family history of myocardial infarction share yet unknown inherited or environmental risk factors of venous thrombosis.

 

The study is published in Circulation: Cardiovascular Genetic

Reference: Lind C, Enga KF, Mathiesen EB, Njølstad I, Brækkan SK, Hansen JB. Family history of myocardial infarction and cause-specific risk of myocardial infarction and venous thromboembolism- the Tromsø study. DOI: 10.1161/CIRCGENETICS.114.000621.



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created: 27.08.2014 09:40
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