Projects

Project #1: Enabling personalized dentistry by increasing the accuracy of caries risk assessment:

Project leader: Associate professor in cariology Jukka Leinonen

Despite the obvious need for accurate caries risk assessment and prediction tools they are not available for adults. An accurately assessed caries risk would enable optimal, personalized dental care according to each individuals’ specific needs. This would in turn decrease health disparities and costs to society. Personalized medicine and the elimination of health disparities are also goals set by the Helsedirektoratet. Unfortunately, existing risk assessment tools have shown only marginal clinical utility. We are developing a multivariable model that would include novel salivary parameters and thereby increase the accuracy of caries risk assessment to a level that is cost-efficient and beneficial to the patient. Especially we study the effect of adding salivary carbonic anhydrase concentration to the multivariable caries prediction model.

Project #2: Determining ways to increase longevity and immediate quality of restorations:

Project leader: Associate professor in cariology Jukka Leinonen

Re-restorations take up about a quarter of all dentists’ working hours. Several studies have shown that the operating dentist has the biggest impact on the longevity of restorations, although obviously diagnostic criteria, patient selection, restorative materials plus patient’s diet, oral hygiene and fluoride frequency effect longevity also. We use retrospective data-collection method to find variables associated with good longevity. We also use microscopic methods to assess the immediate quality of restorations made using different techniques in laboratory environment that mimics the clinical setting. Furthermore, we look for ways to promote valid, up-to-date diagnostic criteria.

Project #3: Treatment of mild and moderate obstructive sleep apnea by continuous positive airway pressure or mandibular advancing splint – a randomized controlled trial on patient specific factors, success rate and compliance:

Ph.d.-student: Lars-Martin Berg
Supervisor: Professor Tordis Trovik (Department of Community Medicine)

Obstructive sleep apnea is a medical condition where repeated collapse of the oro-pharynx during sleep causes breathing cessations. The consequences are reduced quality of sleep, excessive daytime sleepiness, increased risk for developing cardiovascular and metabolic diseases. Obstructive sleep apnea is most often treated by either Continuous Positive Airway Pressure, or Mandibular Advancment Splints, but both treatments are depending on the patient's compliance to be effective. The main objective of the project is to assess how these two treatments differ in respect of efficacy, compliance and impact on health related quality of life among patients diagnosed with mild or moderate obstructive sleep apnea.