MBI-8004 | UiT

Application deadline

PhD course. PhD students and students at the Medical Student Research Program at UiT - The Arctic University of Norway apply for admission by registering for class by December 15.

Application deadline for other applicants is December 1st. Application code 9303 in Søknadsweb.

Type of course

This course is available as a singular course.

The course is organized by the Department of Medical Biology and the Norwegian PhD School of Heart Research (NorHeart).

The course is arranged every second year.

Admission requirements

To take PhD courses you need at a minimum a master's degree or equivalent, or admission to a Medical Student Research Program.

For information about how to apply for admission, go to:

http://uit.no/helsefak/forskning/phd/emner

Applicants who are affiliated with the national research school Norwegian PhD School of Heart Research (NorHeart) will be prioritized for admission if the number of applicants exceeds the course capacity of 8 students.

If fewer than six participants have applied to the course, the course will be cancelled.

Recommended prerequisite Course in experimental animal science for researchers (Category C) or similar course

Course content

Students shall prepare individually by studying 15 selected peer reviewed scientific articles which together account for about 100 000 words. These articles will be regular experimental studies and some review articles covering myocardial energetics and mitochondrial respiration. All students meet in a joint three-day gathering at the Faculty of Health Sciences, UiT - The arctic university of Norway, campus Tromsø, to attend lab demonstrations with related theoretical instructions. It will be performed demonstrations for measuring myocardial metabolism and energetics with the use of; 1) whole animals (anesthetized pig), 2) isolated organs (ex vivo working mouse/rat heart) and 3) isolated organelles (mitochondrial respiration). At this gathering the students will also present and criticize one of the featured articles for the whole group in a 20 minute lecture.

Objectives of the course

After completing the course the students will have the

Knowledge to:

Outline the key factors that affect the heart's efficiency, metabolism and respiration of mitochondria.

Skills to:

Be able to critically evaluate scientific papers where it has been used experimental methods for measuring cardiac efficiency and metabolism.
Acquired a basic understanding of the experimental setup for assessing myocardial metabolism, mitochondrial respiration and invasive cardiac function.

Competence to:

Understand the biological foundation of how changes in metabolism may lead to pathophysiological changes in the cardiovascular system.

Language of instruction and examination

English

Teaching methods

Theoretical study, introductory lectures, practical work in the lab and presentation of a selected article.

Assessment

Work Requirements

Conducted lab experiment and presentation of a selected scientific paper.

Examination and assessment

Home exam with a one-week deadline. Submission of an essay based on a title given by the examination committee. 5 pages, A4, single spaced, Times New Roman 12 pt. Exam can be written in English or Scandinavian. Evaluated as pass/fail.

A re-sit exam will be arranged for this course. Application deadline for the re-sit exam is August 15th.

spring 2019 MBI-8004 Metabolic and Mechanical Function of the Heart - 3 ECTS