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Nannan Yang

Associate professor
Department of Community Medicine

Job description:

-Scientific operations of research biobank

-Research




Research interests

Biospecimen quality, peptide and cancer

Publications in CRIStin


  • Andriukaitiene, Laura; Song, Xiaobo; Yang, Nannan; Lassila, Lippo V.J.; Vallittu, Pekka K.; Kerosuo, Eero. The effect of smear layer removal on E.faecalis leakage and bond strength of four resin-based root canal sealers. BMC Oral Health 2018; Volum 18:213. ISSN 1472-6831.s 1 - 9.s doi: 10.1186/s12903-018-0655-7.

  • Eike, Liv-Marie; Yang, Nannan; Rekdal, Øystein; Sveinbjørnsson, Baldur. The oncolytic peptide LTX-315 induces cell death and DAMP release by mitochondria distortion in human melanoma cells. OncoTarget 2015; Volum 6 (33). ISSN 1949-2553.s 34910 - 34923.s doi: 10.18632/oncotarget.5308.

  • Rekdal, Øystein; Haug, Bengt Erik; Kalaaji, manar; Hunter, Howard N.; Lindin, Inger; Israelsson, Ingrid; Solstad, Terese; Yang, Nannan; Brandl, Martin; Mantzilas, Dimitrios; Vogel, Hans J.. The relative spatial positions of tryptophan and cationic residues in helical membrane-active peptides determines their cytotoxicity. Journal of Biological Chemistry 2012; Volum 287 (1). ISSN 0021-9258.s 233 - 244.s doi: 10.1074/jbc.M111.279281.

  • Fedøy, Anita-Elin; Fedoy, AE; Yang, Nannan; Martinez, A; Leiros, Hanna-Kirsti S.; Steen, IH. Structural and functional properties of isocitrate dehydrogenase from the psychrophilic bacterium Desulfotalea psychrophila reveal a cold-active enzyme with an unusual high thermal stability. Journal of Molecular Biology 2007; Volum 372. ISSN 0022-2836.s 130 - 149.s doi: 10.1016/j.jmb.2007.06.040.

  • Stokke, R; Leiros, Ingar; Karlström, Mikael; Karlstrom, M; Yang, Nannan; Ladenstein, R; Birkeland, NK; Steen, IH. Thermal stability of isocitrate dehydrogenase from Archaeoglobus fulgidus studied by crystal structure analysis and engineering of chimers. Extremophiles 2007; Volum 11. ISSN 1431-0651.s doi: 10.1007/s00792-006-0060-z.

  • Yang, Nannan; Strøm, Morten B.; Mekonnen, Seble Merid; Svendsen, John Sigurd; Rekdal, Øystein. The effects of shortening lactoferrin derived peptides against tumour cells, bacteria and normal human cells. Journal of Peptide Science 2004; Volum 10. ISSN 1075-2617.s 37 - 46.

  • Yang, Nannan; Mekonnen, Seble Merid; Solstad, Terese; Wikman, Mari; Kalaaji, manar; Sylte, Ingebrigt; Rekdal, Øystein. Enhanced tumor cell specificity by optimizing the relative position between aromatic and cationic residues in helical amphipathic peptides. 2003 ISBN 82-497-0155-0.

  • Yang, Nannan; Lejon, Tore Sigvard; Rekdal, Øystein. ANTITUMOUR ACTIVITY AND SPECIFICITY AS A FUNCTION OF SUBSTITUTIONS IN THE LIPOPHILIC SECTOR OF HELICAL LACTOFERRIN-DERIVED PEPTIDE. Journal of Peptide Science 2003; Volum 9. ISSN 1075-2617.s 300 - 311.

  • Yang, Nannan; Strøm, Morten B.; Mekonnen, Seble Merid; Svendsen, John Sigurd; Rekdal, Øystein. The effect of shortening of lactoferrin derived peptides against tumor cells, bacteria and normal human cells. Journal of Peptide Science 2003; Volum 10. ISSN 1075-2617.s 37 - 46.

  • Yang, Nannan; Stensen, Wenche; Svendsen, John Sigurd; Rekdal, Øystein. Enhanced antitumor activity and selectivity of lactoferrin derived peptides. Journal of Peptide Research 2002; Volum 60. ISSN 1397-002X.s 187 - 196.

  • Eike, Liv-Marie; Yang, Nannan; Rekdal, Øystein; Sveinbjørnsson, Baldur. In vitro cytotoxic activities of the membrane active nonapeptide LTX-315 (OncoporeTM) against human melanoma cells. American Association for Cancer Research Annual Meeting 2014 2014-04-05 - 2014-04-09 2014.

  • Yang, Nannan; Jacobsen, Hans-Henry. EUTRO – an IT solution for biobank information management system. BIOBANKS: INTRODUCTION AND NEXT STEPS 2008-11-01 - 2008-11-06 2008.

  • Fedøy, Anita-Elin; Yang, Nannan; Martinez, Aurora; Leiros, Hanna-Kirsti S.; Steen, Ida Helene. A cold-active enzyme with an unusual high thermal stability: Isocitrate dehydrogenase from the psychrophilic bacterium Desulfotalea psychrophila. The Norwegian Biochemical Society 44th Contact Meeting 2008-01-17 - 2008-01-20 2008.

  • Fedøy, Anita-Elin; Yang, Nannan; Martinez, Aurora; Leiros, Hanna-kirsti S.; Steen, Ida Helene. A cold-active enzyme with an unusual high thermal stability: Isocitrate dehydrogenase from the psycrophilic bacterium Desulfotalea psycrophila. Extremophiles 2008 2008-09-07 - 2008-09-11 2008.

  • Yang, Nannan; Jacobsen, Hans-Henry. Biobank unit at the faculty of medicine, University of Tromsø. Euroconference on Biobanking 2007-03-09 - 2007-03-11 2007.

  • Yang, Nannan; Jacobsen, Hans-henry. Biobank unit at Faculty of Medicine, University of Tromsoe. Cell Preservation Technology 2007; Volum 5. ISSN 1538-344X.

  • Yang, Nannan; Jacobsen, Hans-Henry. EUTRO – an IT platform for biobank information management system. International Society for Biological and Environmental Repositories annual meeting 2007-05-30 - 2007-06-02 2007.

  • Yang, Nannan; Njølstad, Inger; Sundsfjord, Arnfinn. Forskningsbiobankene ved DMF - hva har vi og hvor skal vi?. Regional forskningskonferanse innen medisin og helse 2006-11-01 - 2006-11-02 2006.

  • Fedøy, Anita-Elin; Yang, Nannan; Leiros, Hanna-Kirsti S.; Birkeland, Nils-Kåre; Steen, Ida Helene. Biochemical and structural basis of cold-adaptation in isocitrate dehydrogenase from Desulfotalea psychrophila. Extremophiles 2006 2006-09-17 - 2006-09-21 2006.

  • Steen, Ida Helene; Fedøy, Anita-Elin; Yang, Nannan; Leiros, Hanna-Kirsti S.; Karlström, Mikael; Ladenstein, Rudolf; Birkeland, Nils-Kåre. Biochemical characterization and structure analysis of extremophilic isocitrate dehydrogenase. From functional genomics to natural products of marine microorganisms 2006-06-21 - 2006-06-24 2006.

  • Yang, Nannan; Espelid, sigrun; Willassen, Nils Peder; Smalås, Arne Oskar. Hypothetical proteins from Vibrio salmonicida genome: strategies for target selection, cloning and expression. . The Norwegian Biochemical Society 41st Contact meeting 2005-01-13 - 2005-01-16 2005.

  • Yang, Nannan; Karlsen, Solveig; Steen, Ida Helene; Fedoy, AE; Raae, A.J.; Birkeland, NK; Smalås, Arne Oskar. 1.75 Å crystal structure of isocitrate dehydrogenase from Desulfotalea psychrophila. The 3rd Norwegian synchrotron user meeting 2005-05-10 - 2005-05-11 2005.

  • Yang, Nannan; Steen, IH; Karlsen, Solveig; Fedoy, AE; Glærum, L; Stokke, R; Madsen, MS; Andersen, OA; Raae, A.J.; Martinez, A; Birkeland, NK; Smalås, Arne Oskar. Isocitrate dehydrogenases from various organisms: a model system to study structural basis of biological adaptations to extreme temperatures. 10th International Conference on the Crystallization of Biological Macromolecules 2004-06-05 - 2004-06-08 2004.

  • Yang, Nannan. Structural features of amphipathic membrane active peptides: their potential to modulate antitumor activity and tumor cell specificity versus antibacterial activity. 2003 ISBN 82-497-0155-0.

  • Rekdal, Øystein; Svendsen, John Sigurd; Wikman, M.; Solstad, T.; Yang, Nannan. Methods of peptide preparation. 2001.

  • Yang, Nannan; Stensen, Wenche; Svendsen, John Sigurd; Rekdal, Øystein. Effects of altered angle of the cationic sector of lactoferricin analogs on anti-tumor activity and on toxicity towards erythrocytes and fibroblasts. The Norwegian Biochemical Society 36th Contact meeting 2000-01-19 - 2000-01-22 2000.

  • Yang, Nannan. Purification and characterization of PLA2 in marine teleosts. 4TH International Marine Biotechnology Conference 1997-10-01 - 1997-10-08 1997.