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The Neurobiological basis of manual therapies: Quantitative Sensory Testing (QST) as a translational, neurophysiological tool.

The project is a collaborative project with Thomas Weiss, Ph.D. Professor of Biological Psychology and Christian Puta, Ph.D. Institute of Sports Medicine, Friedrich Schiller University, Jena, Germany.

The aim of the project is to explore the "component effect" and "biological mechanisms" of non-pharmacological therapies for back and neck pain. The overall aim is to develop knowledge about how alternative treatment can contribute to relieve or shorten pain in the muscular / skeletal system and thus improve the quality of life in a socioeconomically relevant large patient group.

QST is a well-established diagnostic method within conventional pain research and the clinical investigation of pain patients. NAFKAM uses this methodology on the study of alternative treatments for pain. However, not all sub-tests of the KST test itself have been used to measure therapeutic effects of non-pharmacological pain therapies. Therefore, it is important to explore the stability and reproducibility of the methodology itself.

Project leader: Frauke Musial

Recent publications (others please check NAFKAMs publication overview):

Nothnagel H, Puta C, Lehmann T, Baumbach P, Menard MB, Gabriel B, et al. How stable are quantitative sensory testing measurements over time? Report on 10-week reliability and agreement of results in healthy volunteers. Journal of pain research. 2017;10:2067-78.