Kamilla Gjerland Haugland

Haugland disputerer for ph.d.-graden i helsevitenskap og vil offentlig forsvare avhandlingen:

“Hippocampal plasticity: Development of connectivity and growth hormone modulation of place cells and behavior”

Avhandlingen er tilgjengelig her! / The doctoral thesis is available here!

 

Disputasen og prøveforelesningen blir strømmet. Opptaket av disputasen vil være tilgjengelig i et døgn.
The defense and the trial lecture will be streamed. A recording of the disputation will be available for 24 hours.


Prøveforelesning over oppgitt emne starter kl. 10.15 / The trial lecture starts at 10.15
Tittel/Title: "The role of adult neurogenesis in dentate gyrus function and memory"
Prøveforelesningen strømmes her / The trial lecture will be streamed here

Disputasen starter kl. 12.15 / The defense starts at 12.15
Disputasen strømmes her / The defense will be streamed here

De som ønsker å opponere ex auditorio kan sende e-post til leder av disputasen. 
Opponents ex auditorio should sign up to leader of defense by e-mail to:
endre.anderssen@uit.no

 
Populærvitenskapelig sammendrag av avhandlingen/ Summary of the thesis

The brain is highly plastic and can modify its connections throughout the lifetime. Connections between neurons appear and disappear, in order to strengthen important memories while irrelevant memories fade away.In this thesis, I present three reports about factors that contribute to plasticity in the hippocampus using rats.

The first project utilized an anatomical tracing approach to investigate the development of connections from the hippocampus and parahippocampus to the retrosplenial cortex. We found that connections were present at birth, indicating that these connections are experience-independent. Paper 2 and 3 investigated the plasticity in the adult hippocampus. I used viruses to overexpress growth hormone (GH) in the hippocampus and found that the GH enhanced the hippocampal memory and changed the neural activity.

Revealing the factors affecting hippocampal plasticity is important to understand the mechanisms behind memory deficiency.



Veiledere/ Supervisors:
Hovedveileder/Main supervisor:
Førsteamanuensis Vegard Brun, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet.
Biveileder/supervisors
Førsteamanuensis Kirsten Brun Kjelstrup, Institutt for klinisk medisin, , Det helsevitenskapelige fakultet, UiT Norges arktiske universitet.


Bedømmelseskomité/Defensecomitee:

Professor Francesca Sargolini, Aix‐Marseille University – 1. opponent.
Professor Clive Bramham, Universitetet i Bergen – 2. opponent.
Forsker og Tromsø Research Foundation (TFS) Fellow Shona Wood, institutt for arktisk og marin biologi, Fakultet for biovitenskap, fiskeri og økonomi, UiT Norges arktiske universitet – leder av komité.


Disputasleder/ Leader of defense:
Førsteamanuensis Endre Anderssen, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet.

When: 17.06.21 at 10.15–16.00
Where: Strømmes digitalt
Location / Campus: Digital
Target group: Employees, Students, Guests
Contact: Lill-Iren Gabrielsen Mikalsen
E-mail: lill-iren.g.mikalsen@uit.no
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