Disputas - Master i folkehelsevitenskap og Cand.med. Anna Subbotina

Avhandlingen er tilgjengelig her! / The doctoral thesis is available here!

Auditoriet er åpent for publikum. Disputasen strømmes og et opptak vil være tilgjengelig i et døgn.
The auditorium is open to the public. The defense will still be streamed, and a recording of the disputation will be available for 24 hours.


Prøveforelesning over oppgitt emne starter kl. 10.15 / The trial lecture starts at 10.15
Tittel/Title: " Sex differences in hypertension».
Prøveforelesningen strømmes her / The trial lecture will be streamed here.

Disputasen starter kl. 12.15 / The defense starts at 12.15
Disputasen strømmes her / The defense will be streamed here


Populærvitenskapelig sammendrag av avhandlingen/ Summary of the thesis:

High blood pressure gives little symptoms; about half of sufferers don't know they have it.  Over time, however, it affects multiple organs and can lead to renal and heart injury, stroke, and dementia. One in ten patients struggle to reach healthy blood pressure levels despite taking all the prescribed medications.

Renal denervation is a new treatment opportunity for patients with resistant hypertension. It decreases the overactivity of our sympathetic ("fight-or-flight") nervous system by destroying small nerves around the kidney arteries.

We followed a group of patients treated with renal denervation for two years.  We show that renal denervation lowers blood pressure, especially in patients with very high levels, and slows heart damage in those most affected. It had a slight positive effect on the patient's quality of life. We also showed that specific small molecules, microRNAs, can be detected in blood tests to help predict who benefits most from renal denervation

Veiledere/ Supervisors:
Hovedveileder/Main supervisor:
Professor Terje Steigen, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet.

Biveiledere/supervisors:
Professor Marit Solbu, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet.
Professor Tove Aminda Hanssen, Institutt for helse og omsorgsfag, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet.
Førsteamanuensis Erik Knutsen, Institutt for medisinsk biologi, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet.

Bedømmelseskomité/Defensecomitee:
Professor, Eva Gerdts, UiB – 1. opponent.
Seniorforsker/ph.d. Ingrid Eftedal, NTNU – 2. opponent.
Førsteamanuensis Jørgen Schei, Institutt for klinisk medisin, UiT Norges arktiske universitet – leder av komité.

Disputasleder/ Leader of defense:
Professor Yngve Figenschau, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet.