1. Unit startpage
  2. Employees
  3. Nannan Yang
Bilde av Yang, Nannan
Bilde av Yang, Nannan
Associate professor Department of Community Medicine nannan.yang@uit.no +4777644838 Tromsø You can find me here

Nannan Yang

Job description

-Scientific operations of research biobank

-Research

Work areas

Research support / Quality assurance system / Molecular biology techniques / PCR-Method / Protein analysis / Regulations / Safety and preparedness
  • 1
    Nannan Yang, Turid Hellevik, Rodrigo Berzaghi, Inigo Zubiavrre Martinez :
    Radiation-induced effects on TGF-beta and PDGF receptor signaling in cancer-associated fibroblasts
    Cancer Reports 2024 DOI / ARKIV / ARKIV
  • 1
    Rodrigo Berzaghi, Kristian Gundersen, Brede Dille Pedersen, Amalie Utne, Nannan Yang, Turid Hellevik et al.:
    Immunological signatures from irradiated cancer-associated fibroblasts
    Frontiers in Immunology 06. September 2024 DOI / ARKIV
  • 1
    Nannan Yang, Kristin Lode, Rodrigo Berzaghi, Md Ashraful Islam, Inigo Zubiavrre Martinez, Turid Hellevik :
    Irradiated tumor fibroblasts avoid immune recognition and retain immunosuppressive functions over NK cells
    Frontiers in Immunology 06. December 2020 DOI / ARKIV
  • 1
    Laura Andriukaitiene, Xiaobo Song, Nannan Yang, Lippo V.J. Lassila, Pekka K. Vallittu, Eero Kerosuo :
    The effect of smear layer removal on E. faecalis leakage and bond strength of four resin-based root canal sealers
    BMC Oral Health 2018 DOI / ARKIV
  • 1
    Liv-Marie Eike, Nannan Yang, Øystein Rekdal, Baldur Sveinbjørnsson :
    The oncolytic peptide LTX-315 induces cell death and DAMP release by mitochondria distortion in human melanoma cells
    OncoTarget 13. October 2015 DOI / ARKIV
  • 1
    Øystein Rekdal, Bengt Erik Haug, manar Kalaaji, Howard N. Hunter, Inger Lindin, Ingrid Israelsson et al.:
    The relative spatial positions of tryptophan and cationic residues in helical membrane-active peptides determines their cytotoxicity
    Journal of Biological Chemistry 2012 DOI / ARKIV / ARKIV / ARKIV
  • 1
    Anita-Elin Fedøy, AE Fedoy, Nannan Yang, A Martinez, Hanna-Kirsti S. Leiros, IH Steen :
    Structural and functional properties of isocitrate dehydrogenase from the psychrophilic bacterium Desulfotalea psychrophila reveal a cold-active enzyme with an unusual high thermal stability
    Journal of Molecular Biology (JMB) 2007 DOI / ARKIV
  • 1
    R Stokke, Ingar Leiros, Mikael Karlström, M Karlstrom, Nannan Yang, R Ladenstein et al.:
    Thermal stability of isocitrate dehydrogenase from Archaeoglobus fulgidus studied by crystal structure analysis and engineering of chimers
    Extremophiles 2007 DOI / ARKIV
  • 1
    Nannan Yang, Morten B. Strøm, Seble Merid Mekonnen, John Sigurd Svendsen, Øystein Rekdal :
    The effects of shortening lactoferrin derived peptides against tumour cells, bacteria and normal human cells
    Journal of Peptide Science 2004 ARKIV
  • 1
    Nannan Yang, Morten B. Strøm, Seble Merid Mekonnen, John Sigurd Svendsen, Øystein Rekdal :
    The effect of shortening of lactoferrin derived peptides against tumor cells, bacteria and normal human cells
    Journal of Peptide Science 2003 ARKIV
  • 1
    Nannan Yang, Seble Merid Mekonnen, Terese Solstad, Mari Wikman, manar Kalaaji, Ingebrigt Sylte et al.:
    Enhanced tumor cell specificity by optimizing the relative position between aromatic and cationic residues in helical amphipathic peptides
    2003 ARKIV
  • 1
    Nannan Yang, Tore Sigvard Lejon, Øystein Rekdal :
    ANTITUMOUR ACTIVITY AND SPECIFICITY AS A FUNCTION OF SUBSTITUTIONS IN THE LIPOPHILIC SECTOR OF HELICAL LACTOFERRIN-DERIVED PEPTIDE
    Journal of Peptide Science 2003 ARKIV
  • 1
    Nannan Yang, Wenche Stensen, John Sigurd Svendsen, Øystein Rekdal :
    Enhanced antitumor activity and selectivity of lactoferrin derived peptides
    Journal of Peptide Research 2002 ARKIV
  • Inigo Zubiavrre Martinez, Rodrigo Berzaghi, Laia Gorchs, Kristin Lode, Nannan Yang, Turid Hellevik :
    Immunoregulatory signatures from irradiated Cancer-Associated Fibroblasts
    2025 ARKIV
  • Inigo Zubiavrre Martinez, Turid Hellevik, Rodrigo Berzaghi, Kristin Lode, Nannan Yang :
    Cancer-Associated Fibroblasts in radiotherapy: bystanders or protagonists?
    2022 ARKIV
  • Liv-Marie Eike, Nannan Yang, Øystein Rekdal, Baldur Sveinbjørnsson :
    In vitro cytotoxic activities of the membrane active nonapeptide LTX-315 (OncoporeTM) against human melanoma cells
    2014 ARKIV
  • Nannan Yang, Hans-Henry Jacobsen :
    EUTRO – an IT solution for biobank information management system
    2008 ARKIV
  • Anita-Elin Fedøy, Nannan Yang, Aurora Martinez, Hanna-Kirsti S. Leiros, Ida Helene Steen :
    A cold-active enzyme with an unusual high thermal stability: Isocitrate dehydrogenase from the psychrophilic bacterium Desulfotalea psychrophila
    2008 ARKIV
  • Anita-Elin Fedøy, Nannan Yang, Aurora Martinez, Hanna-kirsti S. Leiros, Ida Helene Steen :
    A cold-active enzyme with an unusual high thermal stability: Isocitrate dehydrogenase from the psycrophilic bacterium Desulfotalea psycrophila
    2008 ARKIV
  • Nannan Yang, Hans-Henry Jacobsen :
    EUTRO – an IT platform for biobank information management system
    2007 ARKIV
  • Nannan Yang, Hans-Henry Jacobsen :
    Biobank unit at the faculty of medicine, University of Tromsø
    2007 ARKIV
  • Nannan Yang, Hans-henry Jacobsen :
    Biobank unit at Faculty of Medicine, University of Tromsoe
    Cell Preservation Technology 2007 ARKIV
  • Nannan Yang, Inger Njølstad, Arnfinn Sundsfjord :
    Forskningsbiobankene ved DMF - hva har vi og hvor skal vi?
    2006 ARKIV
  • Ida Helene Steen, Anita-Elin Fedøy, Nannan Yang, Hanna-Kirsti S. Leiros, Mikael Karlström, Rudolf Ladenstein et al.:
    Biochemical characterization and structure analysis of extremophilic isocitrate dehydrogenase
    2006 ARKIV
  • Anita-Elin Fedøy, Nannan Yang, Hanna-Kirsti S. Leiros, Nils-Kåre Birkeland, Ida Helene Steen :
    Biochemical and structural basis of cold-adaptation in isocitrate dehydrogenase from Desulfotalea psychrophila
    2006 ARKIV
  • Nannan Yang, Solveig Karlsen, Ida Helene Steen, AE Fedoy, A.J. Raae, NK Birkeland et al.:
    1.75 Å crystal structure of isocitrate dehydrogenase from Desulfotalea psychrophila
    2005 ARKIV
  • Nannan Yang, sigrun Espelid, Nils Peder Willassen, Arne Oskar Smalås :
    Hypothetical proteins from Vibrio salmonicida genome: strategies for target selection, cloning and expression
    2005 ARKIV
  • Nannan Yang, IH Steen, Solveig Karlsen, AE Fedoy, L Glærum, R Stokke et al.:
    Isocitrate dehydrogenases from various organisms: a model system to study structural basis of biological adaptations to extreme temperatures
    2004 ARKIV
  • Nannan Yang :
    Structural features of amphipathic membrane active peptides: their potential to modulate antitumor activity and tumor cell specificity versus antibacterial activity
    UiT Norges arktiske universitet 2003 ARKIV
  • Nannan Yang, Wenche Stensen, John Sigurd Svendsen, Øystein Rekdal :
    Effects of altered angle of the cationic sector of lactoferricin analogs on anti-tumor activity and on toxicity towards erythrocytes and fibroblasts
    2000 ARKIV
  • Nannan Yang :
    Purification and characterization of PLA2 in marine teleosts
    1997 ARKIV

    • The 50 latest publications is shown on this page. See all publications in NVA here →

    Research interests

    Biospecimen quality, peptide and cancer


    Member of research group

    Molecular Imaging, Irradiation and Inflammation Research Group-IKM (MIIIRG-IKM)   English content

    CV

    Aug 2007- :     Associate professor, Faculty of Health Sciences/Department of Community Medicine, UiT, Norway

    2006-2007:       Senior engineer, biobank unit, Faculty of medicine, UiT, Norway

    2003-2006:        Postdoc/senior engineer, NORSTRUCT, Faculty of Mathematics and Natural Sciences/Department of Chemistry, UiT, Norway

    1998-2003:        Department engineer/Research assistant, Faculty of Health Sciences/Department of Medical Biology, UiT, Norway

    2013 –2014:       Praktical pedagogical education, UiT The Arctic University of Norway (UiT)

    1999 - 2003:      Department of Medical Biology, University of Tromsø. Dr. Scient. (Ph.D) degree

    1996-1998:        Research Fellow (NFR), Norwegian College of Fishery Science, UiT. Norway

     

    MH øst L10.127


    Click for bigger map