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Bilde av Ströhl, Florian
Bilde av Ströhl, Florian
Principal Investigator | ERC & RCN | Optics Expert Department of Physics and Technology florian.strohl@uit.no +4777645231 You can find me here

Florian Ströhl

Job description

Summary
Dr Ströhl's research is on the development of advanced optical system for use in biology, medicine, and industry. He leads projects covering ultra-violet wavelength imaging system development, production of optic elements, photolithography, optical theory, nanoscopy for use in pathology, and light-sheet microscopy development for regenerative medicine.

With a PhD in Biotechnology and over twelve years of optics research experience, Dr Florian Ströhl has a strong background in designing and managing advanced optical systems, analysing microscopy data, and creating workflows for image acquisition and analysis. Dr Ströhl's work spans application-oriented R&D, optical systems engineering, and project management.

He has a track record of authoring high-quality publications and research experience gathered at world-leading institutions in technology-driven biomedical research (EMBL Heidelberg, University of Cambridge). At UiT, Dr. Ströhl is a Principal Investigator, leading RCN projects on lightsheet microscopy development and an ERC project that will explore mechanosensitive microscopy in regenerative medicine. He is a strong advocate of open science and engages in educational outreach through video content (link to Youtube channel: click me).

New collaborators are always welcome and student projects for theses are available. More information can be found on his group's website (click me) or on LinkedIn (click me).

Areas of Competence

  • optics theory (optical system design, imaging theory, image analysis methods)
  • microscopy method development (SIM, Lightsheet microscopy, single-molecule imaging, labelfree methods, tomography, fluorescence lifetime microscopy)
  • imaging applications (dementia research, liver and kidney pathology, cardiac research, sustainable fish farming)
  • software tools (MATLAB, Optics Studio, ImageJ/Fiji)
  • project management (Norwegian and European grants, leadership of complex projects, managing diverse teams)
  • science communication (YouTube, popular science talks, science-meets-art)

Projects

  • LiBriNa - ERC StG - 2025 - Lightsheet Brillouin Nanoscopy: mechano-sensitive superresolution imaging for regenerative medicine
  • SOLIS - RCN FRIPRO - 2021 - Development of Real Volumetric Microscopy through Single Objective Light-Sheet Imaging System
  • MitoQuant - EU MSCA - 2019 - Development of Deep-UV Quantitative Microscopy for the Study of Mitochondrial Dysfunction

Education

  • Ph.D. in Biotechnology (2018), University of Cambridge, UK
  • M.Sc. (with honours and distinction) in Advanced Optical Technologies (2014), University of Erlangen-Nuremberg, Germany
  • B.Sc. (with BMBF award) in Medical Engineering (2012), University of Erlangen-Nuremberg, Germany

Funding

  • 2025 ERC Starting Grant: 20 million NOK
  • 2023 RCN Innovation Grants: 1 million NOK
  • 2021 RCN FRIPRO Young Grant: 8 million NOK
  • 2019 Horizon 2020 MSCA Grant: 2.1 million NOK
  • EMBO fellow, Nano DTC fellow, OPTICA senior member
  • Jon-Richard Sommernes, Alfred Millett-Sikking, Florian Ströhl :
    S-polarized light-sheets improve resolution and light-efficiency in oblique plane microscopy
    Scientific Reports 2024 ARKIV / DOI
  • Samuel Davis, Jon-Richard Sommernes, sebastian hambura, Levin Riedel, Alejandro Gil, Aissam Ikmi et al.:
    A mesoscopic axially swept oblique plane microscope for imaging of freely moving organisms with near-isotropic resolution
    Biomedical Optics Express 2024 ARKIV / DOI
  • Florian Ströhl :
    Instant Volume Microscopy of Organoids with SOLIS
    Microscopy Today 2023 ARKIV / DOI
  • Marie Reischke, Oliver Vanderpoorten, Florian Ströhl :
    Rapid prototyping of 1xN multifocus gratings via additive direct laser writing
    Micro and Nano Engineering (MNE) 2023 ARKIV / DOI
  • Florian Ströhl, Deanna Wolfson, Ida Sundvor Opstad, Daniel Henry Hansen, Hong Mao, Balpreet Singh Ahluwalia :
    Label-free superior contrast with c-band ultra-violet extinction microscopy
    Light: Science & Applications (LSA) 2023 ARKIV / DOI
  • Florian Ströhl, Ezra Bruggeman, Christopher Rowlands, Deanna Wolfson, Balpreet Singh Ahluwalia :
    Quantification of the NA dependent change of shape in the image formation of a z-polarised fluorescent molecule using vectorial diffraction simulations
    Microscopy research and technique (Print) 2022 ARKIV / DOI
  • Ida Sundvor Opstad, Gustav Godtliebsen, Florian Ströhl, Truls Myrmel, Balpreet Singh Ahluwalia, Krishna Agarwal et al.:
    Three-dimensional structured illumination microscopy data of mitochondria and lysosomes in cardiomyoblasts under normal and galactose-adapted conditions
    Scientific Data 2022 ARKIV / DOI
  • Nikhil Jayakumar, Firehun Tsige Dullo, Vishesh Kumar Dubey, Azeem Ahmad, Florian Ströhl, Jennifer Cauzzo et al.:
    Multi-moded high-index contrast optical waveguide for super-contrast high-resolution label-free microscopy
    Nanophotonics 2022 ARKIV / DOI
  • Florian Ströhl, Daniel Henry Hansen, Mireia Nager Grifo, Åsa Birna Birgisdottir :
    Multifocus microscopy with optically sectioned axial superresolution
    arXiv.org 2022 ARKIV / DOI
  • Florian Ströhl, Daniel Henry Hansen, Mireia Nager Grifo, Åsa birna Birgisdottir :
    Multifocus microscopy with optical sectioning and high axial resolution
    Optica 24. October 2022 ARKIV / DOI
  • Ida Sundvor Opstad, Daniel Henry Hansen, Sebastian Andres Acuña Maldonado, Florian Ströhl, Anish Priyadarshi, Jean-Claude Tinguely et al.:
    Fluorescence fluctuation-based super-resolution microscopy using multimodal waveguided illumination
    Optics Express 2021 ARKIV / DOI
  • Sebastian Andres Acuña Maldonado, Florian Ströhl, Ida Sundvor Opstad, Balpreet Singh Ahluwalia, Krishna Agarwal :
    MusiJ: an ImageJ plugin for video nanoscopy
    Biomedical Optics Express 2020 ARKIV / DOI
  • James D. Manton, Florian Ströhl, Reto Fiolka, Clemens F. Kaminski, Eric J. Rees :
    Concepts for structured illumination microscopy with extended axial resolution through mirrored illumination
    Biomedical Optics Express 2020 ARKIV / DOI
  • Luis Enrique Villegas Hernandez, Mona Nystad, Florian Ströhl, Purusotam Basnet, Ganesh Acharya, Balpreet Singh Ahluwalia :
    Visualizing ultrastructural details of placental tissue with super-resolution structured illumination microscopy
    Placenta 2020 ARKIV / DOI
  • Florian Ströhl, Suyog Jadhav, Balpreet Singh Ahluwalia, Krishna Agarwal, Dilip K. Prasad :
    Object detection neural network improves Fourier ptychography reconstruction
    Optics Express 2020 ARKIV / DOI
  • Lucia Wunderlich, Florian Ströhl, Stefan Ströhl, Oliver Vanderpoorten, Luca Mascheroni, Clemens F. Kaminski :
    Superresolving the kidney – a practical comparison of fluorescence nanoscopy of the glomerular filtration barrier
    Analytical and Bioanalytical Chemistry 05. December 2020 ARKIV / DOI
  • Ida Sundvor Opstad, Florian Ströhl, Marcus J. Fantham, Colin Hockings, Oliver Vanderpoorten, Francesca W. van Tartwijk et al.:
    A waveguide imaging platform for live-cell TIRF imaging of neurons over large fields of view
    Journal of Biophotonics 17. February 2020 ARKIV / DOI
  • Florian Ströhl :
    Multifocus Gratings - Principle and Production
    30. May 2024
  • Florian Ströhl :
    Brillouin Microscopy Development at the Arctic University of Norway
    2024
  • Jon-Richard Sommernes, Florian Ströhl :
    S-polarized light-sheets improve resolution and light efficiency in Oblique Plane Microscopy
    2024
  • Florian Ströhl :
    The basics of optical alignment
    Imaging and Microscopy 2024 ARKIV
  • Florian Ströhl :
    Multifocus Microscopy with Optical Sectioning
    2023
  • Florian Ströhl :
    New Methods for 3D Microscopy
    2023
  • Ida Sundvor Opstad, Sebastian Andres Acuna Maldonado, Stefan Ströhl, Florian Ströhl, Balpreet Singh Ahluwalia, Krishna Agarwal :
    Blind reconstruction of challenging raw data outperforms commercial 3DSIM
    2023
  • Ida Sundvor Opstad, Sebastian Andres Acuna Maldonado, Stefan Ströhl, Florian Ströhl, Balpreet Singh Ahluwalia, Krishna Agarwal :
    Blind reconstruction of challenging raw data outperforms commercial 3DSIM
    2023
  • Felix Hutmacher, Ida Sundvor Opstad, Fabian Hutmacher, Florian Ströhl :
    Visualizing the invisible: Microscopy and how it affects our understanding of cells and tissue
    Springer 2023
  • Florian Ströhl :
    S-polarized light-sheets improve resolution and light-efficiency in oblique plane microscopy
    2023
  • Florian Ströhl :
    3D+time microscopy of organoids:​ challenges and solutions​
    2023
  • Florian Ströhl :
    3D+time microscopy of organoids: challenges and solutions
    2023 FULLTEKST
  • Jean-Claude Tinguely, Vishesh Kumar Dubey, Sebastian Andres Acuna Maldonado, Ida Sundvor Opstad, Luis Enrique Villegas Hernandez, Florian Ströhl et al.:
    Integrated optical circuits for multimodal super-resolution microscopy
    2023
  • Florian Ströhl :
    The missing donut problem
    25. January 2022 FULLTEKST
  • Ida Sundvor Opstad, Daniel Henry Hansen, Sebastian Andres Acuna Maldonado, Florian Ströhl, Anish Priyadarshi, Jean-Claude Tinguely et al.:
    Large area super-resolution TIRFM of arctic fish species
    2022
  • Florian Ströhl :
    Towards label-free widefield nanoscopy within the Abbe limit
    2022
  • Florian Ströhl :
    3D microscopy development at the Arctic University
    2022
  • Florian Ströhl :
    Optically sectioned multi-focus microscopy
    2022
  • Florian Ströhl :
    Technology development for 4D microscopy
    2022
  • Jon-Richard Sommernes, Florian Ströhl :
    3D vectorial diffraction simulations of oblique plane microscopy systems with solid immersion tertiary objectives
    2022
  • Florian Ströhl :
    Instant Volume Imaging
    24. October 2022 FULLTEKST
  • Florian Ströhl :
    Instant Volume Microscopy
    2022
  • Nikhil Jayakumar, Firehun Tsige Dullo, Vishesh Kumar Dubey, Azeem Ahmad, Florian Ströhl, Jennifer Cauzzo et al.:
    Erratum: Multi-moded high-index contrast optical waveguide for super-contrast high-resolution label-free microscopy (Nanophotonics DOI: 10.1515/nanoph-2022-0500.pdf)
    Nanophotonics 2022 DOI
  • Jean-Claude Tinguely, Ida Sundvor Opstad, Sebastian Acuña, Luis E. Villegas-Hernandez, Vishesh Dubey, Florian Ströhl et al.:
    Integrated photonics for super-resolution microscopy
    2022
  • Rolland Tomas, Florian Ströhl :
    Han bygger neste generasjons mikroskop
    20. November 2022 FULLTEKST
  • Florian Ströhl, Daniel Henry Hansen, Jon-Richard Sommernes, Marie Reischke, Mireia Nàger, Åsa birna Birgisdottir :
    Instant Volume Microscopy
    2022
  • Florian Ströhl :
    3D&UV – exploring new concepts in advanced imaging
    2022
  • Florian Ströhl :
    Optical transfer functions in inverted high-resolution light-sheet microscopy
    2021
  • Florian Ströhl, Julie Qiaojin Lin, Francesca W. van Tartwijk, Hovy Ho Wai Wong, Christine E. Holt, Clemens F. Kaminski :
    A Protocol for Single-Molecule Translation Imaging in Xenopus Retinal Ganglion Cells
    Springer 2020 ARKIV
  • Sebastian Andres Acuña Maldonado, Florian Ströhl, Balpreet Singh Ahluwalia, Ida Sundvor Opstad, Krishna Agarwal :
    MUSICAL – An imageJ tool for fluorescence nanoscopy of living cells
    2020
  • Luis Enrique Villegas Hernandez, Vishesh Kumar Dubey, Florian Ströhl, Mona Nystad, Purusotam Basnet, Ganesh Acharya et al.:
    NanoPath. High-throughput and high-resolution pathology using chip-based nanoscopy
    2020
  • Florian Ströhl :
    My experience on how to gain funding for research
    2020
  • Ida Sundvor Opstad, Daniel Henry Hansen, Ole Kristian Svartaas, Eskil Mossige Kjølstad, Deanna Wolfson, Krishna Agarwal et al.:
    A CHIP-BASED IMAGING SYSTEM FOR FAST-CRAWLING SKIN CELLS OF ATLANTIC SALMON –A COOL SURFACE LAYER INVESTIGATION
    2020

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