Jakub Pospíšil
Job description
I am a researcher working on the development of a Brillouin microscopy–based imaging system. My work focuses on the design and implementation of a label-free optical microscope that combines Brillouin scattering with advanced illumination and detection concepts to enable spatially resolved measurements of mechanical properties in biological samples. The project involves optical system design, integration of novel optical elements for hyperspectral imaging, and adaptation of concepts from lightsheet microscopy and nanoscopy to study viscoelastic properties of living tissue with high spatial and temporal resolution.
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Research interests
- Brillouin microscopy and mechanosensitive optical imaging
- Optical system design for advanced microscopy
- Label-free imaging of mechanical properties in biological samples
- Hyperspectral imaging and spectroscopic microscopy
- Image processing and quantitative image analysis
- Liver sinusoidal endothelial cells (LSECs)
- Super-resolution structured illumination microscopy (SR-SIM)
Scopus Author ID: 55424670500
Google Scholar: Jakub Pospíšil
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Jakub Pospíšil was born in Jindřichův Hradec, Czech Republic, in 1990. He graduated from the High School of Electrical Engineering in Třebíč in 2010, with a specialization in Electronic Computer Systems. He subsequently obtained a Master's degree (Ing., equivalent to M.Sc.) in Electrical Engineering, specialization in Communication, Multimedia and Electronics, from the Czech Technical University in Prague (CTU), Faculty of Electrical Engineering, in 2015.
He enrolled in the doctoral study program at the Faculty of Electrical Engineering, CTU, in 2015 and defended his doctoral thesis entitled "Compact structured illumination microscopy and performance evaluation in live cell super-resolution imaging" in 2022.
In July 2022, Jakub Pospíšil joined the Vascular Biology Research Group (VBRG), Department of Medical Biology, UiT The Arctic University of Norway, where he worked as a postdoctoral research fellow. His research during this period focused on liver sinusoidal endothelial cells (LSECs). He is also interested in segmentation and quantitative analysis of biological images.
Since October 2025, he has been working on the development of Brillouin microscopy at the Ultrasound, Microwave and Optics Research Group, Department of Physics, UiT The Arctic University of Norway.