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  3. Elin Moe
Bilde av Moe, Elin
Photo: Ukjent
Bilde av Moe, Elin
Associate Professor II, Biomolecular and Structural Chemistry Department of Chemistry elin.moe@uit.no

Elin Moe

  • Bruno A. Salgueiro, Margarida Saramago, Mark D. Tully, Federico Issoglio, Sara T. N. Silva, Ana C. F. Paiva et al.:
    SARS-CoV2 Nsp1 is a metal-dependent DNA and RNA endonuclease
    Biometals 2024 ARKIV / DOI
  • Carlota J. F. Conceição, Elin Moe, Paulo A. Ribeiro, Maria Raposo :
    Liposome Formulations for the Strategic Delivery of PARP1 Inhibitors: Development and Optimization
    Nanomaterials 2023 ARKIV / DOI
  • Carlota J.F. Conceição, Bruno A. Salgueiro, Paulo A. Ribeiro, Maria Raposo, Elin Moe :
    Advances in the expression and purification of human PARP1: A user-friendly protocol
    Protein Expression and Purification 2023 ARKIV / DOI
  • Filipe Rollo, Guilherme D. Martins, André G. Gouveia, Solenne Ithurbide, Pascale Servant, Célia V. Romão et al.:
    Insights into the role of three Endonuclease III enzymes for oxidative stress resistance in the extremely radiation resistant bacterium Deinococcus radiodurans
    Frontiers in Microbiology 2023 ARKIV / DOI
  • Andreia Fernandes, Adele Kim Williamson, Pedro M. Matias, Elin Moe :
    Structure/function studies of the NAD+-dependent DNA ligase from the poly-extremophile Deinococcus radiodurans reveal importance of the BRCT domain for DNA binding
    Extremophiles 2023 ARKIV / DOI
  • A. Fernandes, Yvonne Piotrowski, Adele Kim Williamson, K. Frade, Elin Moe :
    Studies of multifunctional DNA polymerase I from the extremely radiation resistant Deinococcus radiodurans: Recombinant expression, purification and characterization of the full-length protein and its large fragment
    Protein Expression and Purification 2021 DOI
  • Aili Sarre, Meike Stelter, Filipe Rollo, Salvatore De Bonis, Anna Seck, Cecilia Hognon et al.:
    The three Endonuclease III variants of Deinococcus radiodurans possess distinct and complementary DNA repair activities
    DNA Repair 2019 ARKIV / DOI
  • Joanna Timmins, Elin Moe :
    A Decade of Biochemical and Structural Studies of the DNA Repair Machinery of Deinococcus radiodurans: Major Findings, Functional and Mechanistic Insight and Challenges
    Computational and Structural Biotechnology Journal 2016 ARKIV / DOI
  • Laila Niiranen, Kjersti Lian, Kenneth A Johnson, Elin Moe :
    Crystal structure of the DNA polymerase III β subunit (β-clamp) from the extremophile Deinococcus radiodurans
    BMC Structural Biology 2015 ARKIV / DOI
  • Kjersti Lian, Hanna-Kirsti S. Leiros, Elin Moe :
    MutT from the fish pathogen Aliivibrio salmonicida is a cold-active nucleotide-pool sanitization enzyme with unexpectedly high thermostability
    FEBS Open Bio 2015 ARKIV / DOI
  • Hege Lynum Pedersen, Kenneth Johnson, Colin McVey, Ingar Leiros, Elin Moe :
    Structure determination of uracil-DNA N-glycosylase from Deinococcus radiodurans in complex with DNA
    Acta Crystallographica Section D: Biological Crystallography 2015 ARKIV / DOI
  • Aili Sarre, Mats Ökvist, Tobias Klar, David Hall, Arne O. Smalås, Sean McSweeney et al.:
    Structural and functional characterization of two unusual endonuclease III enzymes from Deinococcus radiodurans
    Journal of Structural Biology 2015 DOI
  • Elin Moe, Netsanet Gizaw Assefa, Ingar Leiros, Kathrin Torseth, Arne O. Smalås, Nils Peder Willassen :
    Reduced Hydrophobicity of the Minor Groove Intercalation Loop is Critical for Efficient Catalysis by Cold Adapted Uracil-DNA N-Glycosylase from Atlantic Cod
    Journal of Thermodynamics & Catalysis 2015 DOI
  • Elin Moe, Murat Sezer, Peter Hildebrandt, Smilja Todorovic :
    Surface enhanced vibrational spectroscopic evidence for an alternative DNA-independent redox activation of endonuclease III
    Chemical Communications 2015 DOI
  • Aili Sarre, Mats Ökvist, Tobias Klar, Elin Moe, Joanna Timmins :
    Expression, purification and crystallization of two endonuclease III enzymes from Deinococcus radiodurans
    Acta Crystallographica. Section F : Structural Biology and Crystallization Communications 01. December 2014 DOI
  • Netsanet Gizaw Assefa, Laila Niiranen, Kenneth Johnson, Hanna-Kirsti S. Leiros, Arne O. Smalås, Nils Peder Willassen et al.:
    Structural and biophysical analysis of interactions between cod and human uracil-DNA N-glycosylase (UNG) and UNG inhibitor (Ugi)
    Acta Crystallographica Section D: Biological Crystallography 2014 ARKIV / DOI
  • Netsanet Gizaw Assefa, Laila Niiranen, Nils P Willassen, Arne O. Smalås, Elin Moe :
    Thermal unfolding studies of cold adapted uracil-DNA N-glycosylase (UNG) from Atlantic cod (Gadus morhua). A comparative study with human UNG
    Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology 2012 DOI
  • Elin Moe, D R Hall, Ingar Leiros, Vivi Talstad Monsen, Joanna Timmins, Sean McSweeney :
    Structure-function studies of an unusual 3-methyladenine DNA glycosylase II (AlkA) from Deinococcus radiodurans
    Acta Crystallographica Section D: Biological Crystallography 2012 DOI
  • Inger Lin Uttakleiv Ræder, Elin Moe, Nils Peder Willassen, Arne Oskar Smalås, Ingar Leiros :
    Structure of uracil-DNA N-glycosylase (UNG) from Vibrio cholerae: mapping temperature adaptation through structural and mutational analysis
    Acta Crystallographica. Section F : Structural Biology and Crystallization Communications 2010 DOI
  • Bjørn Altermark, Ronny Helland, Elin Moe, Nils Peder Willassen, Arne Oskar Smalås :
    Structural adaptation of endonuclease I from the cold-adapted and halophilic bacterium Vibrio salmonicida
    Acta Crystallographica Section D: Biological Crystallography 2008 DOI
  • Inger Lin Uttakleiv Ræder, Ingar Leiros, Nils Peder Willassen, Arne Oskar Smalås, Elin Moe :
    Uracil-DNA N-glycosylase (UNG) from the marine, psychrophilic bacterium Vibrio salmonicida shows cold adapted features A comparative analysis to Vibrio cholerae uracil-DNA N-glycosylase
    Enzyme and Microbial Technology 2008 DOI
  • Bjørn Altermark, Ronny Helland, Elin Moe, Nils Peder Willassen, Arne Oskar Smalås :
    Environmental adaptation of endonuclease I from Vibrio salmonicida
    Acta Crystallographica Section D: Biological Crystallography 2008
  • Bjørn Altermark, Laila Mirja Niiranen, Nils Peder Willassen, Arne Oskar Smalås, Elin Moe :
    Comparative studies of endonuclease I from cold-adapted Vibrio salmonicida and mesophilic Vibrio cholerae
    The FEBS Journal 2007 DOI
  • Bjørn Altermark, Steinar Thorvaldsen, Elin Moe, Arne Oskar Smalås, Nils Peder Willassen :
    Sequence comparison and environmental adaptation of a bacterial endonuclease
    Computational biology and chemistry 2007 DOI
  • Ingar Leiros, Marivi P. Nabong, Kristin Grøsvik, Jeanette Ringvoll, GT Haugland, Lene Uldal et al.:
    Structural basis for enzymatic excision of N-1-methyladenine and N-3-methylcytosine from DNA
    EMBO Journal 2007
  • Hanna-Kirsti S. Leiros, AL Pey, M Innselset, Marte Innselset, Elin Moe, Ingar Leiros et al.:
    Structure of phenylalanine hydroxylase from Colwellia psychrerythraea 34H, a monomeric cold active enzyme with local flexibility around the active site and high overall stability
    Journal of Biological Chemistry 2007 DOI
  • Ingar Leiros, MP Nabong, Marivi Nabong, K Grosvik, Kristin Grøsvik, J Ringvoll et al.:
    Structural basis for enzymatic excision of N-1-methyladenine and N-3-methylcytosine from DNA
    EMBO Journal 2007 DOI
  • Marit Sjo Lorentzen, Elin Moe, HM Jouve, Nils Peder Willassen :
    Cold adapted features of Vibrio salmonicida catalase: characterisation and comparison to the mesophilic counterpart from Proteus mirabilis
    Extremophiles 2006
  • RJ Dennis, E. Micossi, J.J. McCarthy, Elin Moe, E. Gordon, S. Kozielski-Stuhrmann et al.:
    Structure of the manganese superoxide dismutase from Deinococcus radiodurans in two crystal forms
    Acta Crystallographica. Section F : Structural Biology and Crystallization Communications 2006
  • Elin Moe, Ingar Leiros, Arne Oskar Smalås, Sean McSweeney :
    The crystal structure of mismatch-specific uracil-DNA glycosylase (MUG) from Deinococcus radiodurans reveals a novel catalytic residue and broad substrate specificity
    Journal of Biological Chemistry 06. January 2006
  • Atle Noralf Larsen, Elin Moe, Ronny Helland, Dag Rune Gjellesvik, Nils Peder Willassen :
    Characterization of a recombinantly expressed proteinase K-like enzyme from a psychrotrophic Serratia sp
    The FEBS Journal 2006
  • Magne Olufsen, Arne Oskar Smalås, Elin Moe, Bjørn Olav Brandsdal :
    Increased flexibility as a strategy for cold adaptation - A comparative molecular dynamics study of cold- and warm-active uracil DNA glycosylase
    Journal of Biological Chemistry 2005
  • Concetta De Santi, Ragnhild Whitaker, Elin Moe, Fredrik Almqvist, Nils Peder Willassen, Peik Haugen :
    MicroMBT: Microbial communities and moving bed technology as tools for conversion of marine biomass
    2017
  • Marcin Miroslaw Pierechod, Concetta De Santi, Ragnhild Whitaker, Elin Moe, Henrik Antti, Fredrik Almqvist et al.:
    MicroMBT: Microbial communities and moving bed technology as tools for conversion of Marine Biomass
    2017
  • Concetta De Santi, Ragnhild Dragøy Whitaker, Elin Moe, Fredrik Almqvist, Nils Peder Willassen, Peik Haugen :
    MicroMBT: Microbial communities and moving bed technology as tools for conversion of marine biomass
    2016
  • Elin Moe, Ingar Leiros, David Hall, Aili Sarre, Arne O. Smalås, Sean McSweeney et al.:
    Base Excision Repair (BER) in Deinococcus radiodurans
    2015
  • Davi de Miranda Fonseca, Cecilie Christensen Baar, Netsanet Gizaw Assefa, Elin Moe, Nina-Beate Liabakk, Hanna-Kirsti S. Leiros et al.:
    Thermo-sensitive human UNG-mutants
    2013
  • Davi de Miranda Fonseca, Elin Moe, Nina-Beate Liabakk, Cecilie Christensen Baar, Frank Skorpen, Hans Einar Krokan :
    Thermo-sensitive mutants of UNG protein studied by structural experiments – Perspectives
    2012
  • Hege Lynum Pedersen, Laila Niiranen, Kjersti Lian, Aili Sarre, Joanna Timmins, Sean McSweeney et al.:
    Protein interaction studies of BER proteins from the extreme radiation resistant bacterium Deinococcus radiodurans
    2010
  • Laila Niiranen, Hege Lynum Pedersen, Kjersti Lien, Aili Sarre, Joanna Timmins, S McSweeney et al.:
    Identification of novel interaction partners for DNA glycosylases in the extreme radiation resistant bacterium Deinococcus radiodurans
    2009
  • Netsanet Gizaw Assefa, Elin Moe, Arne Oskar Smalås, Nils Peder Willassen :
    Thermodynamic characterization of uracil-DNA N-glycosylase (UNG) from Atlantic cod (Gadus morhua)
    The FEBS Journal 2008
  • Elin Moe, Ingar Leiros, David Richard Hall, Arne Oskar Smalås, Sean McSweeney :
    Structure/function studies of Base Excision Repair (BER) enzymes from the extreme radiation resistant bacterium Deinococcus radiodurans
    2008
  • Hanna-Kirsti S. Leiros, Angel L. Pey, M Innselset, Elin Moe, Ingar Leiros, Ida Helene Steen et al.:
    Crystal Structure of phenylalanine hydroxylase from Colwellia psychrerythraea 34H reveals a monomeric cold active enzyme with local flexibility around the active site and high overall stability
    2008
  • Ingar Leiros, Marivi P. Nabong, GT Haugland, Jeanette Ringvoll, K Grøsvik, K Grøsvik et al.:
    Excision of 1-methyladenine and 3-methylcytosine from DNA by AfAlkA of Archaeoglobus fulgidus
    2006
  • Bjørn Altermark, Ronny Helland, Laila Mirja Niiranen, Elin Moe, Bjørn Olav Brandsdal, Arne Oskar Smalås et al.:
    Optimum enzymatic activity of endonuclease I from Vibrio salmonicida and Vibrio cholerae correlateswith the bacterial growth habitat
    2006
  • Inger Lin Uttakleiv Ræder, Ingar Leiros, Nils Peder Willassen, Arne Oskar Smalås, Elin Moe :
    Uracil-DNA N-glycosylase (UNG) from the marine psychrophilic bacterium Vibrio salmonicida shows cold adapted features
    2006
  • Elin Moe, Joanna Timmins, David Richard Hall, Ingar Leiros, Sean McSweeney :
    Structure-function studies of DNA repair proteins from Deinococcus radiodurans
    2006
  • Ingar Leiros, Marivi P. Nabong, Gyri Teien Haugland, Jeanette Ringvoll, Kristin Grøsvik, Elin Moe et al.:
    Excision of 1-methyladenine and 3-methylcytosine from DNA by AfAlkA of Archaeoglobus fulgidus.
    2006
  • Elin Moe, Ingar Leiros, Arne Oskar Smalås, Sean McSweeney :
    Crystallisation and structure determination of a mismatch specific DNA glycosylase (MUG) from Deinococcus radiodurans
    2005
  • Elin Moe, Ingar Leiros, Arne Oskar Smalås, Sean McSweeney :
    Crystallisation and structure determination of uracil-DNA glycosylases from Deinococcus radiodurans and Vibrio salmonicida. A Collaboration between ESRF and NorStruct
    2005

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    Teaching

    Kje-3603 Protein production technology