Florian van der Ent,
Susann Skagseth,
Bjarte Aarmo Lund,
Jaka Sočan,
Julia J. Griese,
Bjørn Olav Brandsdal
et al.:
Computational design of the temperature optimum of an enzyme reaction
Katarzyna Palica,
Fritz Deufel,
Susann Skagseth,
Gabriela Paula Di Santo Metzler,
Johannes Thoma,
Anna Andersson Rasmussen
et al.:
α-Aminophosphonate inhibitors of metallo-β-lactamases NDM-1 and VIM-2
RSC Medicinal Chemistry 2023
DOI
Katarzyna Palica,
Manuela Vorácová,
Susann Skagseth,
Anna Andersson Rasmussen,
Lisa Allander,
Madlen Hubert
et al.:
Metallo-β-Lactamase Inhibitor Phosphonamidate Monoesters
Ørjan Samuelsen,
Ove Alexander Høgmoen Åstrand,
Christopher Frøhlich,
Adam Heikal,
Susann Skagseth,
Trine Josefine Olsen Carlsen
et al.:
ZN148 Is a Modular Synthetic Metallo-beta-Lactamase Inhibitor That Reverses Carbapenem Resistance in Gram-Negative Pathogens In Vivo
Antimicrobial Agents and Chemotherapy 2020
ARKIV /
DATA /
DOI
Zeeshan Muhammad,
Susann Skagseth,
Marc Boomgaren,
Sundus Akhter,
Christopher Frøhlich,
Aya Ismael
et al.:
Structural studies of triazole inhibitors with promising inhibitor effects against antibiotic resistance metallo-β-lactamases
Bioorganic & Medicinal Chemistry 01. August 2020
ARKIV /
DOI
Susann Skagseth,
Sundus Akhter,
Marianne H. Paulsen,
Muhammad Zeeshan,
Silje Lauksund,
Ørjan Samuelsen
et al.:
Metallo-β-lactamase inhibitors by bioisosteric replacement: preparation, activity and binding
European Journal of Medicinal Chemistry 2017
ARKIV /
DOI
Susann Skagseth,
Tony Christopeit,
Sundus Akhter,
Annette Bayer,
Ørjan Samuelsen,
Hanna-Kirsti S. Leiros
:
Structural insights into TMB-1 and the role of residues 119 and 228 in substrate and inhibitor binding
Antimicrobial Agents and Chemotherapy 2017
ARKIV /
DOI
Susann Skagseth,
Trine Josefine Olsen Carlsen,
Gro Elin Kjæreng Bjerga,
James Spencer,
Ørjan Samuelsen,
Hanna-Kirsti S. Leiros
:
Role of residues W228 and Y233 in the structure and activity of metallo-β-lactamase GIM-1
Antimicrobial Agents and Chemotherapy 2016
ARKIV /
DOI
Hanna-Kirsti S. Leiros,
Susann Skagseth,
Kine Susann Waade Edvardsen,
Marit Sjo Lorentzen,
Gro Elin Kjæreng Bjerga,
Ingar Leiros
et al.:
His224 alters the R2 drug binding site and Phe218 influences the catalytic efficiency of the metallo-β-lactamase VIM-7
Antimicrobial Agents and Chemotherapy 2014
DOI
Vibeke Os,
Susann Skagseth,
Hanna-Kirsti S. Leiros
:
"Superbugs" skal ikke lengre få herje i fred, Vil gjenreise effekten av antibiotika.
Susann Skagseth,
Hanna-Kirsti S. Leiros
:
Forskere vil gjenreise effekten av antibiotika. https://forskning.no/kortnytt/forskere-vil-gjenreise-effekten-av-antibiotika
Susann Skagseth
:
The impact of residue 119 and 228 in the Tripoli metallo-β-lactamase TMB-1 involved in resistance to β-lactam antibiotics" Biostruct conference
2016
Susann Skagseth,
Ørjan Samuelsen,
Hanna-Kirsti S. Leiros
:
The impact of residues 119 and 228 in the Tripoli metallo-beta-lactamase TMB-1 involved in resistance to beta-lactam antibiotics
2016
Tony Christopeit,
Trine Josefine Olsen Carlsen,
Anastasia Albert,
Susann Skagseth,
Hanna-Kirsti S. Leiros
:
Discovery of a Novel Covalent Inhibitor of the Metallo-beta-lactamase NDM-1
2016
Susann Skagseth,
Trine Josefine Olsen Carlsen,
Sundus Akhter,
Muhammad Zeeshan,
Ove Alexander Høgmoen Åstrand,
Annette Bayer
et al.:
The fight against metallo-beta-lactamases and antibiotic resistance
2015
Tony Christopeit,
Trine Josefine Olsen Carlsen,
Susann Skagseth,
Bjarte Aarmo Lund,
Ørjan Samuelsen,
Hanna-Kirsti S. Leiros
:
Using fragment screening to identify novel starting points for potent inhibitors of metallo-beta-lactamase VIM-2
2015
Tony Christopeit,
Bjarte Aarmo Lund,
Trine Josefine Olsen Carlsen,
Susann Skagseth,
Ørjan Samuelsen,
Hanna-Kirsti S. Leiros
:
Using Fragment Screening to Identify Novel Starting Points for Potent Carbapenemase Inhibitors
2015
Susann Skagseth,
Trine Josefine Olsen Carlsen,
Sundus Akhter,
Muhammad Zeeshan,
Ove Alexander Høgmoen Åstrand,
Annette Bayer
et al.:
The fight against metallo-beta-lactamases and antibiotic resistance
2015
Susann Skagseth,
Trine Josefine Olsen Carlsen,
Tony Christopeit,
Sundus Akhter,
Muhammad Zeeshan,
Ove Alexander Høgmoen Åstrand
et al.:
The fight against metallo-beta-lactamases and antibiotic resistance
2015
Susann Skagseth,
Trine Josefine Olsen Carlsen,
Gro Elin Kjæreng Bjerga,
Annette Bayer,
Ørjan Samulesen,
Hanna-Kirsti S. Leiros
:
The importance of residue W228 and Y233 in the metallo-beta-lactamase GIM-1
2014
Marianne H. Paulsen,
Stig Olov Magnus Engqvist,
Ørjan Samuelsen,
Hanna-Kirsti S. Leiros,
Susann Skagseth,
Kinga Leszczak
et al.:
Synthesis of potential metallo-beta-lactamase inhibitors
2014
Susann Skagseth,
Trine Josefine Olsen Carlsen,
Gro Elin Kjæreng Bjerga,
Annette Bayer,
Ørjan Samuelsen,
Hanna-Kirsti S. Leiros
:
The importance of residue Trp228 and Tyr233 in the metallo-beta-lactamase GIM-1
2014
Tony Christopeit,
Trine Josefine Olsen Carlsen,
Susann Skagseth,
Bjarte Aarmo Lund,
Ørjan Samuelsen,
Hanna-Kirsti S. Leiros
:
Characterization of substrate and inhibitor binding to different beta-lactamases using Surface Plasmon Resonance based biosensors
2014
Susann Skagseth,
Kine Susann Waade Edvardsen,
Gro Elin Kjæreng Bjerga,
marit sjo Lorentzen,
Ingar Leiros,
Ørjan Samulesen
et al.:
Site-directed mutagenesis of metallo-beta-lactamase VIM-7 from the opportunistic human pathogenic bacteria Pseudomonas aeruginosa
2013