Ansatte-IK-Jørn-Hansen
Photo: Ukjent
Ansatte-IK-Jørn-Hansen
Department of Chemistry jorn.h.hansen@uit.no +4777645992 40768633 Tromsø REALF C 406

Jørn H Hansen


Associate Professor, Chemical Synthesis and Analysis

Job description

Associate Professor Organic Synthesis/Medicinal Chemistry, Merited Teacher, Head of the Chemical Synthesis and Analysis Group 

Research, Education and administrative work.


  • Aya Ismael, Muhammad Zeeshan, Jørn H Hansen :
    Synthesis of aromatic lactone analogues of Lipoxin A4
    BMC Research Notes 2022 ARKIV / DOI
  • Vijayaragavan Elumalai, Tomaz Trobec, Maja Grundner, Christophe Labriere, Robert Frangez, Kristina Sepcic et al.:
    Development of potent cholinesterase inhibitors based on a marine pharmacophore
    Organic and biomolecular chemistry 2022 DOI
  • Vijayaragavan Elumalai, Jørn H Hansen :
    Synthesis of 5,7-diarylindoles via Suzuki-Miyaura coupling in water
    Organic and biomolecular chemistry 2021 ARKIV / DOI
  • Lotta Turunen, Jørn H Hansen, Máté Erdélyi :
    Halogen Bonding: An Odd Chemistry?
    The chemical record 2021 FULLTEKST / ARKIV / DOI
  • Christophe Labriere, Gunnar Cervin, Henrik Pavia, Jørn H Hansen, Johan Svenson :
    Structure–Activity Relationship Probing of the Natural Marine Antifoulant Barettin
    Marine Biotechnology 2021 DOI
  • Vijayaragavan Elumalai, Jørn H Hansen :
    A Green, Scalable, and Catalyst-Free One-Minute Synthesis of Quinoxalines
    SynOpen 2021 ARKIV / DOI
  • T. W. Zewde, Dejene Kifle, Jostein a Johansen, Taye Beyene Demissie, Jørn H Hansen, Zenebe Tadesse :
    Cyanobacterial abundance and microcystins in water, seston and fish tissues in Lake Hora-Arsedi (Ethiopia)
    African Journal of Aquatic Science 2020 DOI
  • Vijayaragavan Elumalai, Jørn H Hansen :
    A scalable and green one-minute synthesis of substituted phenols
    RSC Advances 2020 ARKIV / DOI
  • Tone Kristoffersen, Vijayaragavan Elumalai, Eliot Starck, Étienne Cousin, Lucille J. Wagner, Stephanie Ramona Hansen et al.:
    Microwave‐Assisted Synthesis of Heterocycles from Aryldiazoacetates
    European Journal of Organic Chemistry 2020 ARKIV / FULLTEKST / DATA / DOI
  • Vijayaragavan Elumalai, Jørn H Hansen :
    A Green, Scalable, One-Minute Synthesis of Benzimidazoles
    Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry 2020 ARKIV / DOI
  • Roberto Bartholomeus Wilhelmus Bekker, Richard Fjellaksel, Trine Hjornevik, Syed Nuruddin, Waqas Rafique, Jørn H Hansen et al.:
    Discovery of a lead brain-penetrating gonadotropin-releasing hormone receptor antagonist with saturable binding in brain
    ChemMedChem 2020 ARKIV / DOI
  • Christophe Labriere, Vijayaragavan Elumalai, Jannie Staffansson, Gunnar Cervin, Tiffany Le Norcy, Hugo Denardou et al.:
    Phidianidine A and Synthetic Analogues as Naturally Inspired Marine Antifoulants
    Journal of natural products 2020 ARKIV / DOI
  • Samson Tilahun, Demeke Kifle, Tigist W Zewde, Jostein a Johansen, Taye Beyene Demissie, Jørn H Hansen :
    Temporal dynamics of intra-and extra-cellular microcystins concentrations in Koka reservoir (Ethiopia): Implications for public health risk
    Toxicon 2019 ARKIV / DOI
  • Jørn H Hansen, Richard Fjellaksel :
    Catalytic Intermolecular Functionalization of Benzimidazoles
    IntechOpen 2019 DOI
  • Richard Fjellaksel, Angel Moldes-Anaya, Terje Vasskog, Ana Oteiza, Maria Montserrat Martin-Armas, Ole Kristian Hjelstuen et al.:
    Evaluation by metabolic profiling and in vitro autoradiography of two promising GnRH‐receptor ligands for brain SPECT imaging
    Journal of labelled compounds & radiopharmaceuticals 08. December 2019 ARKIV / DOI
  • Richard Fjellaksel, Ana Oteiza, Montserrat Martin-Armas, Patrick Riss, Ole Kristian Hjelstuen, Samuel Kuttner et al.:
    First in vivo evaluation of a potential SPECT brain radiotracer for the gonadotropin releasing hormone receptor
    BMC Research Notes 2018 ARKIV / DOI
  • Christophe Labriere, Jeanette hammer Andersen, Marte Albrigtsen, Jørn H Hansen, Johan Svenson :
    Heterocyclic cellular lipid peroxidation inhibitors inspired by the marine antioxidant barettin
    Bioorganic chemistry (Print) 2018 ARKIV / DOI
  • Richard Fjellaksel, Rune Sundset, Patrick Riss, Jørn H Hansen :
    Copper-mediated late-stage iodination and 123I-labelling of triazole-benzimidazole bioactives
    Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry 2018 DOI
  • Christophe Labriere, Nahid Kondori, Josefin Seth Caous, Marc Boomgaren, Kerstin Sandblom, Kristina Nilsson-Ekdahl et al.:
    Development and Evaluation of Cationic Amphiphilic Antimicrobial 2,5-Diketopiperazines
    Journal of Peptide Science 2018 DOI
  • Tigist W Zewede, Jostein a Johansen, Demeke Kifle, Taye Beyene Demissie, Jørn H Hansen, Zenebe Tadesse :
    Concentrations of microcystins in the muscle and liver tissues of fish species from Koka reservoir, Ethiopia: A potential threat to public health
    Toxicon 2018 DOI
  • Richard Fjellaksel, Damir Dugalic, Taye Beyene Demissie, Patrick Riss, Ole Kristian Hjelstuen, Rune Sundset et al.:
    An acylation-Finkelstein approach to radioiodination of bioactives: The role of amide group anchimeric assistance
    Journal of Physical Organic Chemistry 2018 FULLTEKST / ARKIV / DOI
  • Taye Beyene Demissie, Kenneth Ruud, Jørn H Hansen :
    Cryptophanes for Methane and Xenon Encapsulation: A Comparative Density Functional Theory Study of Binding Properties and NMR Chemical Shifts
    Journal of Physical Chemistry A 2017 ARKIV / DOI
  • Uranbaatar Erdenebileg, Taye Beyene Demissie, Jørn H Hansen :
    Visible-Light Photocatalytic Double C-H Functionalization of Indoles: A Synergistic Experimental and Computational Study
    Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry 2017 ARKIV / DOI
  • Richard Fjellaksel, Marc Boomgaren, Rune Sundset, Ira Hebold Haraldsen, Jørn H Hansen, Patrick Riss :
    Small molecule piperazinyl-benzimidazole antagonists of the gonadotropin-releasing hormone (GnRH) receptor
    MedChemComm 2017 ARKIV / DOI
  • Tone Kristoffersen, Jørn H Hansen :
    3,4-Dihydroquinoxalin-2-ones: recent advances in synthesis and bioactivities
    Chemistry of Heterocyclic Compounds 2017 ARKIV / DOI
  • Yansong Zhao, Jørn H Hansen, Tobias Boström :
    Extraction of magnetic nanoparticles using magnetic ionic liquids
    Micro & Nano Letters 2016 DOI
  • Taye Beyene Demissie, Jørn H Hansen :
    Mechanism and Site-Selectivity in Visible-Light Photocatalyzed C–H Functionalization: Insights from DFT Calculations
    Journal of Organic Chemistry 2016 DOI
  • Taye Beyene Demissie, Jørn H Hansen :
    Synergy between Experimental and Computational Approaches to Homogeneous Photoredox Catalysis
    Dalton Transactions 2016 ARKIV / DOI
  • Taye Beyene Demissie, Kenneth Ruud, Jørn H Hansen :
    DFT as a Powerful Predictive Tool in Photoredox Catalysis: Redox Potentials and Mechanistic Analysis
    Organometallics 2015 DOI
  • T. W. Zewde, Jostein a Johansen, Demeke Kifle, Taye Beyene Demissie, Jørn H Hansen, Zenebe Tadesse :
    Erratum: ‘Corrigendum to “” [ <153> (<2018>) <85–95>](S0041010118303593)(10.1016/j.toxicon.2018.08.013)
    Toxicon 2019 DOI
  • Uranbaatar Erdenebileg, Jørn H Hansen :
    Selective Photocatalytic Bromination of Indoles
    2018
  • Richard Fjellaksel, Ana Oteiza, armas maria montserrat Martin, Jørn H Hansen, Angel Moldes-Anaya, Terje Vasskog et al.:
    Development and evaluation of gonadotropin releasing hormone SPECT radioligands
    2018 DATA
  • Tone Kristoffersen, Eliot Starck, Stephanie Ramona Hansen, Lucille Wagner, Jørn H Hansen :
    Microwave-assisted synthesis of heterocycles from aryldiazoacetates
    2018
  • Mukesh Yadav, Jana Jágerská, Jørn H Hansen, Olav Gaute Hellesø :
    Sensitivity and response time of an on-chip methane sensor
    2017
  • Richard Fjellaksel, Jørn H Hansen, Angel Moldes-Anaya, armas maria montserrat Martin, Ana Oteiza, Patrick Riss et al.:
    Development and evaluation of gonadotropin releasing hormone (GnRH) SPECT radioligands
    2017 FULLTEKST / DATA
  • Uranbaatar Erdenebileg, Taye Beyene Demissie, Jørn H Hansen :
    Visible-light photocatalytic C-H functionalization of heterocycles
    2017
  • Marc Boomgaren, Birta Ravdna Sarre, Tor Arne Heim Andberg, Bjørn Olav Brandsdal, Johan Isaksson, Jørn H Hansen :
    Synthesis and exploration of a novel molecular scaffold for dUTPase inhibition: Aiming for new anticancer agents
    2017
  • Jana Jágerská, Firehun Tsige Dullo, Susan M. Lindecrantz, Jacqueline Boergers, Jørn H Hansen, Laura Gomez Lechuga et al.:
    Cryptophane-Cladded Interferometric Waveguide Sensor for Aqueous Methane Detection
    2017
  • Tone Kristoffersen, Eline Samuelsen, Phenias Buhire, Lisa Ramstad, Ane Molden, Taye Beyene Demissie et al.:
    Diverse libraries for chemoprospecting and chemical education
    2016
  • Aya Ismael, Muhammad Zeeshan, Jørn H Hansen :
    Novel Synthesis of Lipoxin A4 Analogues
    2016
  • Damir Dugalic, Richard Fjellaksel, Marc Boomgaren, Ole Kristian Hjelstuen, Jørn H Hansen :
    Development and validation of gonadotropin releasing hormone receptor SPECT/PET radioligands
    2016
  • Marc Boomgaren, Osman Gani, Richard Alan Engh, Jørn H Hansen :
    Bioactive Heterocycle Libraries for Anticancer Drug Discovery - Development of Covalent Binding TK Inhibitors
    2016
  • Birta Ravdna Sarre, Patrik Lundström, Marc Boomgaren, Esmeralda Woestenenk, Jørn H Hansen, Tatiana Agback et al.:
    Characterization of human dUTPase, a new target in cancer therapy
    2016
  • Martin Ingvaldsen, Jana Jágerská, Firehun Tsige Dullo, Susan M. Lindecrantz, Magnus Engqvist, Jørn H Hansen et al.:
    Cryptophane-A doped polymers for methane sensing
    2016
  • Jana Jágerská, Firehun Tsige Dullo, Martin Ingvaldsen, Susan M. Lindecrantz, Jørn H Hansen, Stian Solbø et al.:
    On-chip methane sensing with a cryptophane-A cladded Mach-Zehnder interferometer
    2016
  • Jana Jágerská, Firehun Tsige Dullo, Martin Ingvaldsen, Susan M. Lindecrantz, Magnus Engqvist, Jørn H Hansen et al.:
    On-chip methane sensors based on cryptophane-A cladded waveguide interferometers
    2016
  • Jana Jágerská, Firehun Tsige Dullo, Martin Ingvaldsen, Susan M. Lindecrantz, Magnus Engqvist, Jørn H Hansen et al.:
    On-Chip Methane Sensing with Cryptophane-A Cladded Waveguide Interferometers
    2016
  • Jørn H Hansen :
    Marine Natural Product Mimics - An Organic Chemists Perspective
    2015
  • Marc Boomgaren, Osman A.B.S.M. Gani, Richard Alan Engh, Jørn H Hansen :
    Bioactive Heterocycle Libraries for Anticancer Drug Discovery
    2015
  • Richard Fjellaksel, Marc Boomgaren, Jørn H Hansen, Rune Sundset :
    New Diagnosis for Alzheimer´s Disease
    2015

  • The 50 latest publications is shown on this page. See all publications in Cristin here →

    Publications outside Cristin

    1. Li, Z.; Boyarskikh, V.; Hansen, J. H.; Musaev, D.; Autschbach, J.; Davies, H. M. L. J. Am. Chem. Soc., 2012,134, 15497.
    2. Hansen, S. R.; Spangler, J.; Hansen, J. H.; Davies, H. M. L. Org. Lett., 2012, 14, 4626.
    3. Qin, C.; Boyarskikh, V.; Hansen, J. H.; Musaev, D. G.; Davies, H. M. L. J. Am. Chem. Soc.,2011, 133, 19198.
    4. Ovalles, S. R.; Hansen, J. H.; Davies, H. M. L. Org. Lett. 2011,13, 4284-4287
    5. Hansen, J. H.; Gregg, T. M.; Ovalles, S. R.; Lian, Y.; Autschbach, J.; Davies, H. M. L. J. Am. Chem. Soc. 2011, 133, 5076-5085.
    6. Hansen, J. H.; Parr, B. T.; Pelphrey, P.; Jin, Q.; Autschbach, J.; Davies, H. M. L. Angew. Chem., Int. Ed., 2011, 50, 2544-2548.
    7. Hansen, J. H.; Davies, H. M. L. Chem. Sci. 2010, 2, 457-461.
    8. Briones, J.F.; Hansen, J. H.;Hardcastle, K.; Autschbach, J.; Davies, H. M. L. J. Am. Chem. Soc., 2010, 132, 17211.
    9. Pelphrey, P.; Hansen, J.; Davies, H. M. L. Chem. Sci. 2010, 1, 254.
    10. Davies, H. M. L.; Hansen, J. Book chapter in: Catalytic Asymmetric Synthesis 3rd ed. (Ed. Ojima, I.) 2010, p. 163-226.
    11. Hansen, J.; Li, B.; Autschbach, J.; Dikarev, E. V.; Davies, H. M. L. J. Org. Chem. 2009, 74, 6564-6571.
    12. Hansen, J.; Autschbach, J.; Davies, H. M. L. J. Org. Chem. 2009, 74, 6555-6563.
    13. Sevryugina, Y.; Weaver, B.; Hansen, J.; Thompson, J.; Davies, H. M. L.; Petrukhina, M. A. Organometallics 2008, 27, 1750-1757.
    14. Hansen, J., Davies, H. M. L. Coord. Chem. Rev. 2008, 252, 545-555.


    Research interests

     1. Bioactive heterocycles

    2. Photo- and transition metal catalysis

    3. Late-Stage Functionalization

    4. Small-molecule PET-radiopharmaceuticals

    5. Molecular sensing

    Check out the Hansen lab website for more information: www.hansenlab.net

    Teaching

    Current:

    KJE1002 Organic Chemistry Basic Course

    KJE3301 Organic Chemistry 2

    KJE3312/8312 Organic Chemistry 3 (biannual)

    KJE3308/8308 Metal-organic Compounds in Organic Synthesis (biannual)

    Previously:

    KJE2003 Basic Analytical Chemistry

    KJE6003 Organic and Analytical Chemistry for Teachers

    KJE3501 Introduction to Research Methodology in Organic Chemistry

    KJE3810 Special curriculum: Photochemistry and photocatalysis


    Member of research group



    CV

     

    EDUCATION

    2010

    Ph.D. – Organic Chemistry

    Emory University, Atlanta, GA, USA (Davies Group)

    University at Buffalo, The State University of New York (Davies Group)

     

    2005

     

    M.Sc./Sivilingeniør  –  Chemistry and Biotechnology,

    Norwegian University of Science and Technology (NTNU) (Carlsen Group)

    PROFESSIONAL EXPERIENCE

    2012–present

    Associate Professor, University of Tromsø, Norway

     

    2012

    Visiting Assistant Professor, Touro College, Manhattan, New York City.

    2010-2012 Postdoctoral Research Associate, Princeton University (MacMillan Group)

    2005-2007 Teaching Assistant, University at Buffalo, The State University of New York
       
       

    REALF C 406

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