Annette Bayer
Head of Department; Professor, Chemical Synthesis and Analysis
Susannah von Hofsten,
Manuel K Langer,
Katja Korelin,
Synnøve Norvoll Magnussen,
Dominik Ausbacher,
Trude Anderssen
et al.:
Amphipathic barbiturates as marine product mimics with cytolytic and immunogenic effects on head and neck squamous cell carcinoma cell lines
Manuel K Langer,
Ataur Rahman,
Hymonti Dey,
Trude Anderssen,
Hans-Matti Blencke,
Tor Haug
et al.:
Investigation of tetrasubstituted heterocycles reveals hydantoins as a promising scaffold for development of novel antimicrobials with membranolytic properties
Lisa Myrseth Hemmingsen,
Barbara Giordani,
Marianne Hagensen Paulsen,
Zeljka Vanic,
Gøril Eide Flaten,
Beatrice Vitali
et al.:
Tailored anti-biofilm activity – Liposomal delivery for mimic of small antimicrobial peptide
Susannah von Hofsten,
Marianne Hagensen Paulsen,
Synnøve Magnussen,
Dominik Ausbacher,
Mathias Kranz,
Annette Bayer
et al.:
The marine natural product mimic MPM-1 is cytolytic and induces DAMP release from human cancer cell lines
Manuel K Langer,
Ataur Rahman,
Hymonti Dey,
Trude Anderssen,
Francesco Zilioli,
Tor Haug
et al.:
A concise SAR-analysis of antimicrobial cationic amphipathic barbiturates for an improved activity-toxicity profile
Lianne H. E. Wieske,
Jonathan Bogaerts,
Albin A. M. Leding,
Scott Wilcox,
Anna Andersson Rasmussen,
Kinga Leszczak
et al.:
NMR Backbone Assignment of VIM-2 and Identification of the Active Enantiomer of a Potential Inhibitor
Ashot Gevorgyan,
Kathrin Helen Hopmann,
Annette Bayer
:
Improved Buchwald-Hartwig Amination by the Use of Lipids and Lipid Impurities
Marianne Hagensen Paulsen,
Magnus Engqvist,
Dominik Ausbacher,
Trude Anderssen,
Manuel K- Langer,
Tor Haug
et al.:
Amphipathic Barbiturates as Mimics of Antimicrobial Peptides and the Marine Natural Products Eusynstyelamides with Activity against Multi-resistant Clinical Isolates
Ashot Gevorgyan,
Kathrin Helen Hopmann,
Annette Bayer
:
Lipids as Versatile Solvents for Chemical Synthesis
Ljiljana Pavlovic,
Martin Pettersen,
Ashot Gevorgyan,
Janakiram Vaitla,
Annette Bayer,
Kathrin Helen Hopmann
:
Computational and experimental insights into asymmetric Rh‐catalyzed hydrocarboxylation with CO2
Ikenna E. Ndukwe,
Yu-hong Lam,
Sunil Kumar Pandey,
Bengt Erik Haug,
Annette Bayer,
Edward C. Sherer
et al.:
Unequivocal structure confirmation of a breitfussin analog by anisotropic NMR measurements
Zeeshan Muhammad,
Susann Skagseth,
Marc Boomgaren,
Sundus Akhter,
Christopher Frøhlich,
Aya Ismael
et al.:
Structural studies of triazole inhibitors with promising inhibitor effects against antibiotic resistance metallo-β-lactamases
Yngve Guttormsen,
Magnus John Espeland Fairhurst,
Sunil Kumar Pandey,
Johan Isaksson,
Bengt Erik Haug,
Annette Bayer
:
Total synthesis of phorbazole B
Aya Ismael,
Ashot Gevorgyan,
Troels Skrydstrup,
Annette Bayer
:
Renewable solvents for palladium-catalyzed carbonylation reactions
Ashot Gevorgyan,
Kathrin Helen Hopmann,
Annette Bayer
:
Exploration of New Biomass-Derived Solvents: Application to Carboxylation Reactions
Ashot Gevorgyan,
Kathrin Helen Hopmann,
Annette Bayer
:
Formal C-H carboxylation of unactivated arenes
Aya Ismael,
Troels Skrydstrup,
Annette Bayer
:
Carbonylative Suzuki-Miyaura couplings of sterically hindered aryl halides: Synthesis of 2-aroylbenzoate derivatives
Ørjan Samuelsen,
Ove Alexander Høgmoen Åstrand,
Christopher Frøhlich,
Adam Heikal,
Susann Skagseth,
Trine Josefine Olsen Carlsen
et al.:
ZN148 Is a Modular Synthetic Metallo-beta-Lactamase Inhibitor That Reverses Carbapenem Resistance in Gram-Negative Pathogens In Vivo
Marc Obst,
Ashot Gevorgyan,
Annette Bayer,
Kathrin Helen Hopmann
:
Mechanistic Insights into Copper-Catalyzed Carboxylations
Marianne Hagensen Paulsen,
Dominik Ausbacher,
Annette Bayer,
Magnus Engqvist,
Terkel Hansen,
Tor Haug
et al.:
Antimicrobial activity of amphipathic α,α-disubstituted β-amino amide derivatives against ESBL–CARBA producing multi-resistant bacteria; effect of halogenation, lipophilicity and
cationic character
Ashot Gevorgyan,
Marc Obst,
Yngve Guttormsen,
Feliu Maseras,
Kathrin Helen Hopmann,
Annette Bayer
:
Caesium Fluoride-Mediated Hydrocarboxylation of Alkenes and Allenes: Scope and Mechanistic Insights
Kine Østnes Hansen,
Jeanette hammer Andersen,
Annette Bayer,
Sunil Kumar Pandey,
Marianne Lorentzen,
Kåre Bredeli Jørgensen
et al.:
Kinase chemodiversity from the Arctic: the breitfussins
Janakiram Vaitla,
Annette Bayer,
Kathrin Helen Hopmann
:
Vinyl Sulfoxonium Ylide: A New Vinyl Carbenoid Transfer Reagent for the Synthesis of Heterocycles
Janakiram Vaitla,
Annette Bayer
:
Sulfoxonium Ylide Derived Metal Carbenoids in Organic Synthesis
Magnus John E. Fairhurst,
Zeeshan Muhammad,
Bengt Erik Haug,
Annette Bayer
:
Aldol condensations on a 3-alkylidene-2,5-diketopiperazine - synthesis of two marine natural products
Sundus Ahkter,
Bjarte Aarmo Lund,
Aya Ismael,
Manuel Langer,
Johan Isaksson,
Tony Christopeit
et al.:
A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design
Janakiram Vaitla,
Annette Bayer,
Kathrin Helen Hopmann
:
Iron‐Catalyzed Carbenoid Transfer Reactions of Vinyl Sulfoxonium Ylides: An Experimental and Computational Study
Ljiljana Pavlovic,
Janakiram Vaitla,
Annette Bayer,
Kathrin Helen Hopmann
:
Rhodium-Catalyzed Hydrocarboxylation: Mechanistic Analysis Reveals Unusual Transition State for Carbon–Carbon Bond Formation
Marianne Hagensen Paulsen,
Eskil Andre Karlsen,
Dominik Ausbacher,
Trude Anderssen,
Annette Bayer,
Philipp Ochtrop
et al.:
An amphipathic cyclic tetrapeptide scaffold containing halogenated β2,2-amino acids with activity
against multi-resistant bacteria
Journal of Peptide Science 2018 DOI
Ataur Rahman,
Manuel K Langer,
Hans-Matti Blencke,
Tor Haug,
Johanna U Ericson,
Morten B. Strøm
et al.:
Development of novel antimicrobial peptides: two classes with improved antimicrobial and antibiofilm activity
2023 PROSJEKT
Guillaume Petit,
Kine Østnes Hansen,
Jeanette Hammer Andersen,
Espen Holst Hansen,
Annette Bayer,
Bengt Erik Haug
et al.:
A fragment to bind them all: Characterising phorbazole fragments as pan-kinase inhibitor
2023
Manuel K Langer,
Annette Bayer
:
Total synthesis of Aspergilone A in batch and flow - A comparison
2023
Manuel K Langer,
Ataur Rahman,
Hymonti Dey,
Trude Anderssen,
Hans-Matti Blencke,
Tor Haug
et al.:
Tetrasubstituted hydantoins: Novel membranolytic antimicrobials
2023
Lisa Myrseth Hemmingsen,
Barbara Giordani,
Marianne Hagensen Paulsen,
Zeljka Vanic,
Gøril Eide Flaten,
Beatrice Vitali
et al.:
Liposomes in topical delivery of mimic of small antimicrobial peptide - Improving the anti-biofilm effect
2023
Alexandra Sofia Antunes de Sousa,
Kjersti Julin,
Annette Bayer,
Morten Bøhmer Strøm,
Mona Johannessen,
Natasa Skalko-Basnet
et al.:
Drug-loaded DNA nanoparticles against bioflms
2023
Ataur Rahman,
Manuel K Langer,
Bartosz Michno,
Hans-Matti Blencke,
Tor Haug,
Johanna U Ericson
et al.:
In vivo toxicity and activity of newly developed novel analogues of short-cationic antimicrobial peptides as novel antibacterial agents
2023
Ataur Rahman,
Manuel K Langer,
Bartosz Michno,
Hans-Matti Blencke,
Tor Haug,
Johanna U Ericson
et al.:
In vivo toxicity and activity of newly developed novel analogues of short-cationic antimicrobial peptides as novel antibacterial agents
2023
Ainara Nova Flores,
Troels Skrydstrup,
Kim Daasbjerg,
Annette Bayer,
Liselotte Karulf
:
Recommendations for Future CO2 Management in the Nordic Countries
Kjersti Julin,
Annette Bayer,
Morten Bøhmer Strøm,
Mona Johannessen,
Natasa Skalko-Basnet,
Sybil Akua Okyerewa Obuobi
:
DNA Nanocarriers for improved biofilm penetration
2022
Susannah von Hofsten,
Marianne Hagensen Paulsen,
Manuel K Langer,
Synnøve Norvoll Magnussen,
Dominik Ausbacher,
Annette Bayer
et al.:
A Compound Inspired by Arctic Marine Animals Kills Cancer Cells in vitro and in vivo
2022
Ataur Rahman,
Manuel Karl Langer,
Hymonti Dey,
Jonathan Hira,
Ekaterina Mishchenko,
Annette Bayer
et al.:
Novel antimicrobial and biofilm-inhibitors from marine resources
2020
Manuel K Langer,
Annette Bayer
:
Tetrasubstituted barbiturates and hydantoins as potential antibiotics
2020
Susannah von Hofsten,
Synnøve Norvoll Magnussen,
Dominik Ausbacher,
Marianne Hagensen Paulsen,
Annette Bayer,
Morten B. Strøm
et al.:
The Marine Natural Product Mimic MHP88 Shows Anticancer Activity and has the Potential to Cause Immunogenic Cell Death
2020 ARKIV
Annette Bayer,
Eldrid Borgan
:
Små hjelpestoffer kan få gammel antibiotika til å virke igjen
13. July 2020
Annette Bayer
:
Structure-based design of carbapenemase inhibitors
2019
Annette Bayer
:
Structure Based Design of Carbapenemase Inhibitors
2019
Annette Bayer
:
Towards Antibiotic Resistance Breakers. Structure-Based Design of Carbapenemase Inhibitors.
2018
Annette Bayer
:
Research in the Bayer/CHOCO group.
2018
Annette Bayer
:
Take your career in your own hands: Make a career development plan!
2018
Annette Bayer
:
Total synthesis of Breitfussin A and B.
2018
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Teaching
- Introductory Organic Chemistry (KJE-1002); in 2019 i implemented a major change to the pedagogical approach - now focusing on systematic understanding of reaction mechanism rather than a system based on the oxidation state of functional groups - and teaching through a flipped-classroom approach.
- Practical Organic Chemistry and Spectroscopy(KJE-1003)
- Intermediate Organic Chemistry (KJE-3301)
- Organometallic Chemistry(KJE-3308/8308)
- Nuclear Magnetic Resonance (KJE-3305/8305)
