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Senior Engineer

Jack-Ansgar Bruun

Department of Medical Biology
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  • Islam, Md Ashraful; Urbarova, Ilona; Bruun, Jack-Ansgar; Martinez, Inigo Zubiavrre. LARGE-SCALE SECRETOME ANALYSES UNVEIL THE SUPERIOR IMMUNOSUPPRESSIVE PHENOTYPE OF UMBILICAL CORD STROMAL CELLS AS COMPARED TO OTHER ADULT MESENCHYMAL STROMAL CELLS. European Cells and Materials 2019; Volum 37. ISSN 1473-2262.s 153 - 174.s doi: 10.22203/eCM.v037a10.

  • Lau, Corinna; McAdam, Martin Berner; Bergseth, Grete; Grevys, Algirdas; Bruun, Jack-Ansgar; Ludviksen, Judith K; Fure, Hilde; Espevik, Terje; Moen, Anders; Andersen, Jan Terje; Mollnes, Tom Eirik. NHDL, a recombinant VL/VH hybrid antibody control for IgG2/4 antibodies.. mAbs 2019; Volum 12:e1686319 (1). ISSN 1942-0862.s 1 - 13.s doi: 10.1080/19420862.2019.1686319.

  • Shrestha, Birendra Kumar; Rasmussen, Mads Skytte; Abudu, Yakubu Princely; Bruun, Jack-Ansgar; Larsen, Kenneth Bowitz; Alemu, Endalkachew Ashenafi; Sjøttem, Eva; Lamark, Trond; Johansen, Terje. NIMA-related kinase 9–mediated phosphorylation of the microtubule-associated LC3B protein at Thr-50 suppresses selective autophagy of p62/sequestosome 1. Journal of Biological Chemistry 2019; Volum 295 (5). ISSN 0021-9258.s 1240 - 1260.s doi: 10.1074/jbc.RA119.010068.

  • Penaranda, Ma Michelle Demogina; Jensen, Ingvill; Greiner-Tollersrud, Linn; Bruun, Jack-Ansgar; Jørgensen, Jorunn B. Profiling the Atlantic Salmon IgM+ B Cell Surface Proteome: Novel Information on Teleost Fish B Cell Protein Repertoire and Identification of Potential B Cell Markers. (Fulltekst: https://doi.org/10.3389/fimmu.2019.00037 Frontiers in Immunology 2019; Volum 10. ISSN 1664-3224.s doi: 10.3389/fimmu.2019.00037.

  • Kumar, Suresh; Gu, Yuexi; Abudu, Yakubu Princely; Bruun, Jack-Ansgar; Jain, Ashish; Farzam, Farzin; Mudd, Michal H.; Anonsen, Jan Haug; Rusten, Tor Erik; Kasof, Gary; Ktistakis, Nicholas; Lidke, Keith A; Johansen, Terje; Deretic, Vojo. Phosphorylation of Syntaxin 17 by TBK1 Controls Autophagy Initiation. Developmental Cell 2019; Volum 49 (1). ISSN 1534-5807.s 130 - 144.e6.s doi: 10.1016/j.devcel.2019.01.027.

  • Cavanagh, Jorunn Pauline; Askarian, Fatemeh; Pain, Maria; Bruun, Jack-Ansgar; Urbarova, Ilona; Wai, Sun Nyunt; Schmidt, Frank; Johannessen, Mona. Proteome profiling of secreted and membrane vesicle associated proteins of an invasive and a commensal Staphylococcus haemolyticus isolate.. Data in Brief 2019; Volum 22. ISSN 2352-3409.s 914 - 919.s doi: 10.1016/j.dib.2018.11.147.

  • Mejlvang, Jakob; Olsvik, Hallvard Lauritz; Svenning, Steingrim; Bruun, Jack-Ansgar; Abudu, Yakubu Princely; Larsen, Kenneth Bowitz; Brech, Andreas; Hansen, Tom Egil; Brenne, Hanne Britt; Hansen, Terkel; Stenmark, Harald Alfred; Johansen, Terje. Starvation induces rapid degradation of selective autophagy receptors by endosomal microautophagy. Journal of Cell Biology 2018; Volum 217 (10). ISSN 0021-9525.s 3640 - 3655.s doi: 10.1083/jcb.201711002.

  • Cavanagh, Jorunn Pauline; Pain, Maria; Askarian, Fatemeh; Bruun, Jack-Ansgar; Urbarova, Ilona; Wai, Sun Nyunt; Schmidt, Frank; Johannessen, Mona. Comparative exoproteome profiling of an invasive and a commensal Staphylococcus haemolyticus isolate. Journal of Proteomics 2018; Volum 18. ISSN 1874-3919.s 1874 - 3919.s doi: 10.1016/j.jprot.2018.11.013.

  • Samuelsen, Jan Tore; Michelsen, Vibeke Barman; Bruun, Jack-Ansgar; Dahl, Jon Einar; Jensen, Einar; Ørtengren, Ulf Thore. The dental monomer HEMA causes proteome changes in human THP-1 monocytes. Journal of Biomedical Materials Research. Part A 2018; Volum 107A (4). ISSN 1549-3296.s 851 - 859.s doi: 10.1002/jbm.a.36601.

  • Nilsen, Bo Wold; Simon-Santamaria, Jaione; Ørtengren, Ulf Thore; Jensen, Einar; Bruun, Jack-Ansgar; Michelsen, Vibeke Barman; Sørensen, Karen Kristine. Dose- and time-dependent effects of triethylene glycol dimethacrylate on the proteome of human THP-1 monocytes. European Journal of Oral Sciences 2018; Volum 126 (5). ISSN 0909-8836.s 345 - 358.s doi: 10.1111/eos.12559.

  • Chauhan, Santosh; Kumar, Suresh; Jain, Ashish; Ponpuak, Marisa; Mudd, Michal H.; Kimura, Tomonori; Choi, Seong Won; Peters, Ryan; Mandell, Michael; Bruun, Jack-Ansgar; Johansen, Terje; Deretic, Vojo. TRIMs and galectins globally cooperate and TRIM16 and galectin-3 co-direct autophagy in endomembrane damage homeostasis. Developmental Cell 2016; Volum 39 (1). ISSN 1534-5807.s 13 - 27.s doi: 10.1016/j.devcel.2016.08.003.

  • Henriksen, Stian; Hansen, Terkel; Bruun, Jack-Ansgar; Rinaldo, Christine Hanssen. The Presumed Polyomavirus Viroporin VP4 of Simian Virus 40 or Human BK Polyomavirus Is Not Required for Viral Progeny Release. Journal of Virology 2016; Volum 90 (22). ISSN 0022-538X.s 10398 - 10413.s doi: 10.1128/JVI.01326-16.

  • Konstantinell, Aelita Gloria Virginia; Bruun, Jack-Ansgar; Olsen, randi; Aspar, Augusta Hlin; Skalko-Basnet, Natasa; Sveinbjørnsson, Baldur; Moens, Ugo. Secretomic analysis of extracellular vesicles originating from polyomavirus-negative and polyomavirus-positive Merkel cell carcinoma cell lines. Proteomics 2016; Volum 16 (19). ISSN 1615-9853.s 2587 - 2591.s doi: 10.1002/pmic.201600223.

  • Gorchs, Laia; Hellevik, Turid; Bruun, Jack-Ansgar; Camilio, Ketil Andre; Al-Saad, Samer; Stuge, Tor Brynjar; Martinez, Inigo Zubiavrre. Cancer-associated fibroblasts from lung tumors maintain their immunosuppressive abilities after high-dose irradiation. Frontiers in Oncology 2015; Volum 5:87. ISSN 2234-943X.s doi: 10.3389/fonc.2015.00087.

  • Jain, Ashish; Rusten, Tor Erik; Katheder, Nadja Sandra; Elvenes, Julianne; Bruun, Jack-Ansgar; Sjøttem, Eva; Lamark, Trond; Johansen, Terje. P62/sequestosome-1, autophagy-related gene 8, and autophagy in Drosophila are regulated by nuclear factor erythroid 2-related factor 2(NRF2), independent of transcription factor TFEB. Journal of Biological Chemistry 2015; Volum 290 (24). ISSN 0021-9258.s 14945 - 14962.s doi: 10.1074/jbc.M115.656116.

  • Hellevik, Turid; Pettersen, Ingvild; Berg, Vivian; Bruun, Jack-Ansgar; Bartnes, Kristian; Busund, Lill-Tove; Chalmers, Anthony; Bremnes, Roy M.; Martinez, Inigo Zubiavrre. Changes in the secretory profile of NSCLC-associated fibroblasts after ablative radiotherapy: Potential impact on angiogenesis and tumor growth. (Fulltekst: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573655/ Translational Oncology 2013; Volum 6 (1). ISSN 1944-7124.s 66 - 74.s doi: 10.1593/tlo.12349.

  • Pilli, Manohar; Arko-Mensah, John; Ponpuak, Marisa; Roberts, Esteban; Master, Sharon; Mandell, Michael A.; Dupont, Nicolas; Ornatowski, Wojciech; Jiang, Shanya; Bradfute, Steven B.; Bruun, Jack-Ansgar; Hansen, Tom Egil; Johansen, Terje; Deretic, Vojo. TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation. Immunity 2012; Volum 37 (2). ISSN 1074-7613.s 223 - 234.s doi: 10.1016/j.immuni.2012.04.015.

  • Polacek, Martin; Bruun, Jack-Ansgar; Elvenes, Jan; Figenschau, Yngve; Martinez, Inigo Zubiavrre. The secretory profiles of cultured human articular chondrocytes and mesenchymal stem cells: implications for autologous cell transplantation strategies. Cell Transplantation 2011; Volum 20 (9). ISSN 0963-6897.s 1381 - 1393.s doi: 10.3727/096368910X550215.

  • Pankiv, Serliy; Alemu, Endalkachew; Brech, Andreas; Bruun, Jack-Ansgar; Lamark, Trond; Øvervatn, Aud Karin; Bjørkøy, Geir; Johansen, Terje. FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport. Journal of Cell Biology 2010; Volum 188 (2). ISSN 0021-9525.s 253 - 269.s doi: 10.1083/jcb.200907015.

  • Polacek, Martin; Bruun, Jack-Ansgar; Johansen, Oddmund; Martinez, Inigo Zubiavrre. Differences in the Secretome of Cartilage Explants and Cultured Chondrocytes Unveiled by SILAC Technology. Journal of Orthopaedic Research 2010; Volum 28 (8). ISSN 0736-0266.s 1040 - 1049.s doi: 10.1002/jor.21067.

  • Pankiv, Serliy; Lamark, Trond; Bruun, Jack-Ansgar; Øvervatn, Aud Karin; Bjørkøy, Geir; Johansen, Terje. Nucleocytoplasmic Shuttling of p62/SQSTM1 and Its Role in Recruitment of Nuclear Polyubiquitinated Proteins to Promyelocytic Leukemia Bodies. Journal of Biological Chemistry 2010; Volum 285 (8). ISSN 0021-9258.s 5941 - 5953.s doi: 10.1074/jbc.M109.039925.

  • Polacek, Martin; Bruun, Jack-Ansgar; Johansen, oddmund; Martinez, Inigo Zubiavrre. Differences in the secretome of cartilage explants and cultured chondrocytes unveiled by SILAC technology. Journal of Orthopaedic Research 2009. ISSN 0736-0266.

  • Kirkin, Vladimir; Lamark, Trond; Sou, Yu-Shin; Bjørkøy, Geir; Nunn, Jennifer Ann Lillebo; Bruun, Jack-Ansgar; Shvets, Elena; McEwan, David G.; Clausen, Terje; Wild, Philipp; Bilusic, Ivana; Theurillat, Jean-Philippe; Øvervatn, Aud Karin; Ishii, Tetsuro; Elazar, Zvulun; Komatsu, Masaaki; Dikic, Ivan; Johansen, Terje. A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates. Molecular Cell 2009; Volum 33 (4). ISSN 1097-2765.s 505 - 516.s doi: 10.1016/j.molcel.2009.01.020.

  • Pankiv, Serliy; Clausen, Terje; Lamark, Trond; Brech, A; Bruun, Jack-Ansgar; Outzen, heidi; Øvervatn, Aud Karin; Bjørkøy, Geir; Johansen, Terje. p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. (Fulltekst: http://www.jbc.org/cgi/content/full/282/33/24131 Journal of Biological Chemistry 2007; Volum 282. ISSN 0021-9258.s 24131 - 24145.s doi: 10.1074/jbc.M702824200.

  • Bruun, Jack-Ansgar; Thomassen, Ernst I.s.; Kristiansen, Kurt; Tylden, Garth Daryl; Holm, Turid; Mikkola, Ingvild; Bjørkøy, Geir; Johansen, Terje. The third helix of the homeodomain of paired class homeodomain proteins acts as a recognition helix both for DNA and protein interactions. Nucleic Acids Research (NAR) 2005; Volum 33. ISSN 0305-1048.

  • Bhandari, Sabin; Li, Ruomei; Kyrrestad, Ingelin; Bruun, Jack-Ansgar; Urbarova, Ilona; Smedsrød, Bård; Martinez, Inigo Zubiavrre; Simon-Santamaria, Jaione; Sørensen, Karen Kristine. Effect of glucocorticoids on liver sinusoidal endothelial cells in vitro. The 2019 Liver Sinusoidal Meeting: 20th International Symposium on Cells of the Hepatic Sinusoid 2019-09-04 - 2019-09-07 2019.

  • Penaranda, Ma Michelle Demogina; Jensen, Ingvill; Tollersrud, Linn G.; Bruun, Jack-Ansgar; Jørgensen, Jorunn B. IDENTIFICATION AND GENE EXPRESSION ANALYSES OF POTENTIAL B CELL SURFACE MARKERS IN ATLANTIC SALMON. 14th International Society of Developmental and Comparative Immunology (ISDCI) Congress 2018-06-17 - 2018-06-21 2018.

  • Penaranda, Ma Michelle Demogina; Jensen, Ingvill; Tollersrud, Linn G.; Bruun, Jack-Ansgar. Identification of Atlantic salmon B cell markers by proteomics (B celle markører fra Atlantisk laks identifisert ved proteomikk). Havbruk 2018 2018-04-18 - 2018-04-20 2018.

  • Li, Ruomei; Simon-Santamaria, Jaione; Bhandari, Sabin; Bruun, Jack-Ansgar; Urbarova, Ilona; Smedsrød, Bård; Martinez, Inigo Zubiavrre; Sørensen, Karen Kristine. Phenotypic changes in rat liver sinusoidal endothelial cells during early stages of in vitro culture. 19th International Symposium of cells of the Hepatic Sinusoid 2017-06-14 - 2017-06-17 2017.

  • Simon-Santamaria, Jaione; Li, Ruomei; Bhandari, Sabin; Bruun, Jack-Ansgar; Smedsrød, Bård; Martinez, Inigo Zubiavrre; Sørensen, Karen Kristine. Secretome of the liver sinusoidal endothelial cell. The 52nd Norwegian Biochemical Society (NBS) Contact Meeting 2016-01-21 - 2016-01-23 2016.

  • Michelsen, Vibeke Barman; Samuelsen, Jan Tore; Bruun, Jack-Ansgar; Dahl, Jon Einar; Jensen, Einar; Ørtengren, Ulf Thore. ENDRINGER I PROTEOMET I HUMANE MONOCYTTER ETTER EKSPONERING FOR METHACRYLATMONOMER FRA DENTALE MATERIALER. 22. Norske Symposium i Kromatografi 2016-01-10 - 2016-01-12 2016.

  • Dahl, Jon Einar; Michelsen, Vibeke Barman; Bruun, Jack-Ansgar; Jensen, Erik; Örtengren, Ulf Tore; Samuelsen, Jan Tore. Proteome Changes Indicate Oxidative Stress and Protein Damage after Methacrylate Exposure in Human Monocyte Cell Line. The Toxicologist 2016; Volum 150. ISSN 0731-9193.s 341 - .

  • Gorchs, Laia; Hellevik, Turid; Bruun, Jack-Ansgar; Camilio, Ketil Andre; Al-Saad, Samer; Stuge, Tor Brynjar; Martinez, Inigo Zubiavrre. Immunoregulatory functions of Cancer-associated Fibroblasts from lung cancers. Cell Symposia: Cancer, Inflammation and immunity 2015-06-14 - 2015-06-16 2015.

  • Gorchs, Laia; Hellevik, Turid; Bruun, Jack-Ansgar; Camilio, Ketil Andre; Al-Saad, Samer; Stuge, Tor Brynjar; Martinez, Inigo Zubiavrre. Cancer-associated fibroblasts from lung tumors maintain their immunosuppressive abilities after high-dose irradiation. Cell Symposia: Cancer, Inflammation & Immunity 2015-06-14 - 2015-06-16 2015.

  • Michelsen, Vibeke Barman; Samuelsen, Jan Tore; Bruun, Jack-Ansgar; Dahl, Jon Einar; Jensen, Einar; Ørtengren, Ulf Thore. Sub-lethal Concentrations of HEMA Alter Protein Expression in Human Monocytes.. IADR/PER Congress 2014-09-10 - 2014-09-13 2014.

  • Hellevik, Turid; Pettersen, ingvild; Winberg, Jan-Olof; Berg, Vivian; Bruun, Jack-Ansgar; Moe, Bjørn Thorvald Greve; Bartnes, Kristian; Busund, Lill-Tove; Chalmers, Anthony; Bremnes, Roy M.; Martinez, Inigo Zubiavrre. Consequential effects of ablative ionizing radiation on tumor stromal fibroblasts from lung tumors. Cell Symposia: Hallmarks of Cancer 2012-10-29 - 2012-10-31 2012.

  • Bhandari, Sabin; Li, Ruomei; Kyrrestad, Ingelin; Bruun, Jack-Ansgar; Urbarova, Ilona; Smedsrød, Bård; Martinez, Inigo Zubiavrre; Simon-Santamaria, Jaione; Sørensen, Karen Kristine. Effect of glucocorticoids on liver sinusoidal endothelial cells in vitro. The 2019 Liver Sinusoidal Meeting: 20th International Symposium on Cells of the Hepatic Sinusoid 2019-09-04 - 2019-09-07 2019.

  • Penaranda, Ma Michelle Demogina; Jensen, Ingvill; Tollersrud, Linn G.; Bruun, Jack-Ansgar; Jørgensen, Jorunn B. IDENTIFICATION AND GENE EXPRESSION ANALYSES OF POTENTIAL B CELL SURFACE MARKERS IN ATLANTIC SALMON. 14th International Society of Developmental and Comparative Immunology (ISDCI) Congress 2018-06-17 - 2018-06-21 2018.

  • Penaranda, Ma Michelle Demogina; Jensen, Ingvill; Tollersrud, Linn G.; Bruun, Jack-Ansgar. Identification of Atlantic salmon B cell markers by proteomics (B celle markører fra Atlantisk laks identifisert ved proteomikk). Havbruk 2018 2018-04-18 - 2018-04-20 2018.

  • Li, Ruomei; Simon-Santamaria, Jaione; Bhandari, Sabin; Bruun, Jack-Ansgar; Urbarova, Ilona; Smedsrød, Bård; Martinez, Inigo Zubiavrre; Sørensen, Karen Kristine. Phenotypic changes in rat liver sinusoidal endothelial cells during early stages of in vitro culture. 19th International Symposium of cells of the Hepatic Sinusoid 2017-06-14 - 2017-06-17 2017.

  • Simon-Santamaria, Jaione; Li, Ruomei; Bhandari, Sabin; Bruun, Jack-Ansgar; Smedsrød, Bård; Martinez, Inigo Zubiavrre; Sørensen, Karen Kristine. Secretome of the liver sinusoidal endothelial cell. The 52nd Norwegian Biochemical Society (NBS) Contact Meeting 2016-01-21 - 2016-01-23 2016.

  • Michelsen, Vibeke Barman; Samuelsen, Jan Tore; Bruun, Jack-Ansgar; Dahl, Jon Einar; Jensen, Einar; Ørtengren, Ulf Thore. ENDRINGER I PROTEOMET I HUMANE MONOCYTTER ETTER EKSPONERING FOR METHACRYLATMONOMER FRA DENTALE MATERIALER. 22. Norske Symposium i Kromatografi 2016-01-10 - 2016-01-12 2016.

  • Dahl, Jon Einar; Michelsen, Vibeke Barman; Bruun, Jack-Ansgar; Jensen, Erik; Örtengren, Ulf Tore; Samuelsen, Jan Tore. Proteome Changes Indicate Oxidative Stress and Protein Damage after Methacrylate Exposure in Human Monocyte Cell Line. The Toxicologist 2016; Volum 150. ISSN 0731-9193.s 341 - .

  • Gorchs, Laia; Hellevik, Turid; Bruun, Jack-Ansgar; Camilio, Ketil Andre; Al-Saad, Samer; Stuge, Tor Brynjar; Martinez, Inigo Zubiavrre. Immunoregulatory functions of Cancer-associated Fibroblasts from lung cancers. Cell Symposia: Cancer, Inflammation and immunity 2015-06-14 - 2015-06-16 2015.

  • Gorchs, Laia; Hellevik, Turid; Bruun, Jack-Ansgar; Camilio, Ketil Andre; Al-Saad, Samer; Stuge, Tor Brynjar; Martinez, Inigo Zubiavrre. Cancer-associated fibroblasts from lung tumors maintain their immunosuppressive abilities after high-dose irradiation. Cell Symposia: Cancer, Inflammation & Immunity 2015-06-14 - 2015-06-16 2015.

  • Michelsen, Vibeke Barman; Samuelsen, Jan Tore; Bruun, Jack-Ansgar; Dahl, Jon Einar; Jensen, Einar; Ørtengren, Ulf Thore. Sub-lethal Concentrations of HEMA Alter Protein Expression in Human Monocytes.. IADR/PER Congress 2014-09-10 - 2014-09-13 2014.

  • Hellevik, Turid; Pettersen, ingvild; Winberg, Jan-Olof; Berg, Vivian; Bruun, Jack-Ansgar; Moe, Bjørn Thorvald Greve; Bartnes, Kristian; Busund, Lill-Tove; Chalmers, Anthony; Bremnes, Roy M.; Martinez, Inigo Zubiavrre. Consequential effects of ablative ionizing radiation on tumor stromal fibroblasts from lung tumors. Cell Symposia: Hallmarks of Cancer 2012-10-29 - 2012-10-31 2012.

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