Florian Ströhl
Job description
Summary
Dr Ströhl's research is on the development of advanced optical system for use in biology, medicine, and industry. He leads projects cover optical system development, production of optic elements, photolithography, optical theory, nanoscopy for use in pathology, mechanosensitive microscopy development, and light-sheet microscopy development for regenerative medicine.
With a PhD in Biotechnology and over twelve years of optics research experience, Dr Florian Ströhl has a strong background in designing and managing advanced optical systems, analysing microscopy data, and creating workflows for image acquisition and analysis. Dr Ströhl's work spans application-oriented R&D, optical systems engineering, and project management.
He has a track record of authoring high-quality publications and research experience gathered at world-leading institutions in technology-driven biomedical research (EMBL Heidelberg, University of Cambridge). At UiT, Dr. Ströhl is a Principal Investigator, leading RCN projects on lightsheet microscopy development and an ERC project that will explore mechanosensitive microscopy in regenerative medicine. He is a strong advocate of open science and engages in educational outreach through video content (link to Youtube channel: click me).
New collaborators are always welcome and student projects for theses are available. More information can be found on his group's website (click me) or on LinkedIn (click me).
Areas of Competence
- optics theory (optical system design, imaging theory, image analysis methods)
- microscopy method development (SIM, Lightsheet microscopy, single-molecule imaging, labelfree methods, tomography, fluorescence lifetime microscopy)
- imaging applications (dementia research, liver and kidney pathology, cardiac research, sustainable fish farming)
- software tools (MATLAB, Optics Studio, ImageJ/Fiji)
- project management (Norwegian and European grants, leadership of complex projects, managing diverse teams)
- science communication (YouTube, popular science talks, science-meets-art)
Projects
- LiBriNa - ERC StG - 2025 - Lightsheet Brillouin Nanoscopy: mechano-sensitive superresolution imaging for regenerative medicine
- SOLIS - RCN FRIPRO - 2021 - Development of Real Volumetric Microscopy through Single Objective Light-Sheet Imaging System
- MitoQuant - EU MSCA - 2019 - Development of Deep-UV Quantitative Microscopy for the Study of Mitochondrial Dysfunction
Education
- Ph.D. in Biotechnology (2018), University of Cambridge, UK
- M.Sc. (with honours and distinction) in Advanced Optical Technologies (2014), University of Erlangen-Nuremberg, Germany
- B.Sc. (with BMBF award) in Medical Engineering (2012), University of Erlangen-Nuremberg, Germany
Funding
- 2025 ERC Starting Grant: 20 million NOK
- 2023 RCN Innovation Grants: 1 million NOK
- 2021 RCN FRIPRO Young Grant: 8 million NOK
- 2019 Horizon 2020 MSCA Grant: 2.1 million NOK
- EMBO fellow, Nano DTC fellow, OPTICA senior member
Jon-Richard Sommernes,
Alfred Millett-Sikking,
Florian Ströhl
:
S-polarized light-sheets improve resolution and light-efficiency in oblique plane microscopy
Samuel Davis,
Jon-Richard Sommernes,
sebastian hambura,
Levin Riedel,
Alejandro Gil,
Aissam Ikmi
et al.:
Mesoscopic axially swept oblique plane microscope for the imaging of freely moving organisms with near-isotropic resolution
Florian Ströhl
:
Instant Volume Microscopy of Organoids with SOLIS
Marie Reischke,
Oliver Vanderpoorten,
Florian Ströhl
:
Rapid prototyping of 1xN multifocus gratings via additive direct laser writing
Florian Ströhl,
Deanna Wolfson,
Ida Sundvor Opstad,
Daniel Henry Hansen,
Hong Mao,
Balpreet Singh Ahluwalia
:
Label-free superior contrast with c-band ultra-violet extinction microscopy
Nikhil Jayakumar,
Firehun Tsige Dullo,
Vishesh Kumar Dubey,
Azeem Ahmad,
Florian Ströhl,
Jennifer Cauzzo
et al.:
Multi-moded high-index contrast optical waveguide for super-contrast high-resolution label-free microscopy
Florian Ströhl,
Daniel Henry Hansen,
Mireia Nager Grifo,
Åsa Birna Birgisdottir
:
Multifocus microscopy with optically sectioned axial superresolution
Florian Ströhl,
Daniel Henry Hansen,
Mireia Nager Grifo,
Åsa birna Birgisdottir
:
Multifocus microscopy with optical sectioning and high axial resolution
Florian Ströhl,
Ezra Bruggeman,
Christopher Rowlands,
Deanna Wolfson,
Balpreet Singh Ahluwalia
:
Quantification of the NA dependent change of shape in the image formation of a z-polarised fluorescent molecule using vectorial diffraction simulations
Ida Sundvor Opstad,
Gustav Godtliebsen,
Florian Ströhl,
Truls Myrmel,
Balpreet Singh Ahluwalia,
Krishna Agarwal
et al.:
Three-dimensional structured illumination microscopy data of mitochondria and lysosomes in cardiomyoblasts under normal and galactose-adapted conditions
Ida Sundvor Opstad,
Daniel Henry Hansen,
Sebastian Andres Acuña Maldonado,
Florian Ströhl,
Anish Priyadarshi,
Jean-Claude Tinguely
et al.:
Fluorescence fluctuation-based super-resolution microscopy using multimodal waveguided illumination
Sebastian Andres Acuña Maldonado,
Florian Ströhl,
Ida Sundvor Opstad,
Balpreet Singh Ahluwalia,
Krishna Agarwal
:
MusiJ: an ImageJ plugin for video nanoscopy
James D. Manton,
Florian Ströhl,
Reto Fiolka,
Clemens F. Kaminski,
Eric J. Rees
:
Concepts for structured illumination microscopy with extended axial resolution through mirrored illumination
Luis Enrique Villegas Hernandez,
Mona Nystad,
Florian Ströhl,
Purusotam Basnet,
Ganesh Acharya,
Balpreet Singh Ahluwalia
:
Visualizing ultrastructural details of placental tissue with super-resolution structured illumination microscopy
Florian Ströhl,
Suyog Jadhav,
Balpreet Singh Ahluwalia,
Krishna Agarwal,
Dilip K. Prasad
:
Object detection neural network improves Fourier ptychography reconstruction
Lucia Wunderlich,
Florian Ströhl,
Stefan Ströhl,
Oliver Vanderpoorten,
Luca Mascheroni,
Clemens F. Kaminski
:
Superresolving the kidney – a practical comparison of fluorescence nanoscopy of the glomerular filtration barrier
Ida Sundvor Opstad,
Florian Ströhl,
Marcus J. Fantham,
Colin Hockings,
Oliver Vanderpoorten,
Francesca W. van Tartwijk
et al.:
A waveguide imaging platform for live-cell TIRF imaging of neurons over large fields of view
Florian Ströhl
:
Multifocus Gratings - Principle and Production
30. May 2024
Florian Ströhl
:
Brillouin Microscopy Development at the Arctic University of Norway
2024
Jon-Richard Sommernes,
Florian Ströhl
:
S-polarized light-sheets improve resolution and light efficiency in Oblique Plane Microscopy
2024
Florian Ströhl
:
The basics of optical alignment
Imaging and Microscopy 2024 ARKIV
Jean-Claude Tinguely,
Vishesh Kumar Dubey,
Sebastian Andres Acuna Maldonado,
Ida Sundvor Opstad,
Luis Enrique Villegas Hernandez,
Florian Ströhl
et al.:
Integrated optical circuits for multimodal super-resolution microscopy
2023
Florian Ströhl
:
Multifocus Microscopy with Optical Sectioning
2023
Florian Ströhl
:
New Methods for 3D Microscopy
2023
Ida Sundvor Opstad,
Sebastian Andres Acuna Maldonado,
Stefan Ströhl,
Florian Ströhl,
Balpreet Singh Ahluwalia,
Krishna Agarwal
:
Blind reconstruction of challenging raw data outperforms commercial 3DSIM
2023
Ida Sundvor Opstad,
Sebastian Andres Acuna Maldonado,
Stefan Ströhl,
Florian Ströhl,
Balpreet Singh Ahluwalia,
Krishna Agarwal
:
Blind reconstruction of challenging raw data outperforms commercial 3DSIM
2023
Felix Hutmacher,
Ida Sundvor Opstad,
Fabian Hutmacher,
Florian Ströhl
:
Visualizing the invisible: Microscopy and how it affects our understanding of cells and tissue
Springer 2023
Florian Ströhl
:
S-polarized light-sheets improve resolution and light-efficiency in oblique plane microscopy
2023
Florian Ströhl
:
3D+time microscopy of organoids: challenges and solutions
2023
Florian Ströhl
:
3D+time microscopy of organoids: challenges and solutions
2023 FULLTEKST
Florian Ströhl
:
3D microscopy development at the Arctic University
2022
Florian Ströhl
:
Optically sectioned multi-focus microscopy
2022
Florian Ströhl
:
Technology development for 4D microscopy
2022
Jon-Richard Sommernes,
Florian Ströhl
:
3D vectorial diffraction simulations of oblique plane microscopy systems with solid immersion tertiary objectives
2022
Florian Ströhl
:
Instant Volume Imaging
24. October 2022 FULLTEKST
Florian Ströhl
:
Instant Volume Microscopy
2022
Nikhil Jayakumar,
Firehun Tsige Dullo,
Vishesh Kumar Dubey,
Azeem Ahmad,
Florian Ströhl,
Jennifer Cauzzo
et al.:
Erratum: Multi-moded high-index contrast optical waveguide for super-contrast high-resolution label-free microscopy (Nanophotonics DOI: 10.1515/nanoph-2022-0500.pdf)
Nanophotonics 2022 DOI
Jean-Claude Tinguely,
Ida Sundvor Opstad,
Sebastian Acuña,
Luis E. Villegas-Hernandez,
Vishesh Dubey,
Florian Ströhl
et al.:
Integrated photonics for super-resolution microscopy
2022
Rolland Tomas,
Florian Ströhl
:
Han bygger neste generasjons mikroskop
20. November 2022 FULLTEKST
Florian Ströhl,
Daniel Henry Hansen,
Jon-Richard Sommernes,
Marie Reischke,
Mireia Nàger,
Åsa birna Birgisdottir
:
Instant Volume Microscopy
2022
Florian Ströhl
:
3D&UV – exploring new concepts in advanced imaging
2022
Florian Ströhl
:
The missing donut problem
25. January 2022 FULLTEKST
Ida Sundvor Opstad,
Daniel Henry Hansen,
Sebastian Andres Acuna Maldonado,
Florian Ströhl,
Anish Priyadarshi,
Jean-Claude Tinguely
et al.:
Large area super-resolution TIRFM of arctic fish species
2022
Florian Ströhl
:
Towards label-free widefield nanoscopy within the Abbe limit
2022
Florian Ströhl
:
Optical transfer functions in inverted high-resolution light-sheet microscopy
2021
Florian Ströhl,
Julie Qiaojin Lin,
Francesca W. van Tartwijk,
Hovy Ho Wai Wong,
Christine E. Holt,
Clemens F. Kaminski
:
A Protocol for Single-Molecule Translation Imaging in Xenopus Retinal Ganglion Cells
Springer 2020 ARKIV
Sebastian Andres Acuña Maldonado,
Florian Ströhl,
Balpreet Singh Ahluwalia,
Ida Sundvor Opstad,
Krishna Agarwal
:
MUSICAL – An imageJ tool for fluorescence nanoscopy of living cells
2020
Luis Enrique Villegas Hernandez,
Vishesh Kumar Dubey,
Florian Ströhl,
Mona Nystad,
Purusotam Basnet,
Ganesh Acharya
et al.:
NanoPath. High-throughput and high-resolution pathology using chip-based nanoscopy
2020
Florian Ströhl
:
My experience on how to gain funding for research
2020
Ida Sundvor Opstad,
Daniel Henry Hansen,
Ole Kristian Svartaas,
Eskil Mossige Kjølstad,
Deanna Wolfson,
Krishna Agarwal
et al.:
A CHIP-BASED IMAGING SYSTEM FOR FAST-CRAWLING SKIN CELLS OF ATLANTIC SALMON –A COOL SURFACE LAYER INVESTIGATION
2020
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Research interests
My research interests focus on the development of advanced optical systems for use in biology, medicine, and industry. I am particularly interested in optical system development, the production of optic elements, photolithography, and optical theory. Additionally, I am passionate about advancing microscopy methods, including nanoscopy for pathology, mechanosensitive microscopy, and light-sheet microscopy for regenerative medicine. I am committed to exploring innovative imaging applications in areas such as dementia research, liver and kidney pathology, cardiac research, and sustainable fish farming.