Molecular and Clinical Aspects of Cancer - block I

Det helsevitenskapelige fakultet

Theoretical

The course is divided into three modules: Module I cover the topics molecular genetics of cancer, and discuss the basic molecular mechanisms leading to development of cancer. The main issues are mechanisms for cell-cycle regulation, proliferation, transformation and cell survival. How dysregulation of any of these processes may contribute to cancer development is discussed. The topic of Module II is signal transduction and cancer. Here the various intracellular signalling pathways that are found to be dysregulated in cancer are discussed. Among these are the pathways that regulate cell proliferation, cell survival, transformation and differentiation. Module III is covering tumour biology. Here the main mechanisms that regulate metastasis, angionegenesis, and apoptosis are described. These processes are fundamental for embryogenesis, but are also central in the establishment and maintenance of cancer cells.

English

The course has multiple teaching approaches