Molecular and Clinical Aspects of Cancer - block II

This is a Ph.D. - course.

The course is divided into three modules: Module I cover the topics DNA repair, Transcriptional regulation, Chromatin and Epigenetics and the impact of these processes for maintenance and proper proliferation and differentiation of the cell. How dysregulation of any these processes may contribute to cancer development is discussed. The topics of Module II are infectious agents and their involvement in different cancer types, and cancer epidemiology. The infectious agents discussed are mainly prokaryotes and viruses, and how some of their encoded proteins have the ability to disturb the normal regulation of a eukaryotic cell. The epidemiology part discusses the impact of genetic and environmental factors in cancer development. Module III discusses factors that may have a preventive effect on cancer development, molecular medicines and how such medicines specifically hit the oncoproteins and thereby inhibit growth of cancer cells.

English

3 oral presentations of articles (1 for each module); presented in plenary discussions.