Molecular and Clinical Aspects of Cancer - block II
About the course
The course is divided into three modules:
Module I cover the topics DNA repair, Transcriptional regulation, Chromatin and Epigenetics and the impact of these processes for maintenance and proper proliferation and differentiation of the cell. How dysregulation of any these processes may contribute to cancer development is discussed.
The topics of Module II are infectious agents and their involvement in different cancer types, and cancer epidemiology. The infectious agents discussed are mainly prokaryotes and viruses, and how some of their encoded proteins have the ability to disturb the normal regulation of a eukaryotic cell. The epidemiology part discusses the impact of genetic and environmental factors in cancer development.
Module III discusses factors that may have a preventive effect on cancer development, molecular medicines and how such medicines specifically hit the oncoproteins and thereby inhibit growth of cancer cells.
Objectives of the course
The student should know the main mechanisms of DNA repair, Transcriptional regulation, Chromatin and Epigenetics and the impact of these processes for maintenance and proper proliferation and differentiation of the cell, and describe how dysregulation of any these processes may contribute to cancer development.
The student should know how proteins encoded by infectious agents have the ability to disturb the normal regulation of a eukaryotic cell and contribute to cancer development.
The student should know the impact of genetic and environmental factors in cancer development.
The student should be able to describe factors that may have a preventive effect on cancer development, molecular medicines and how such medicines specifically hit the oncoproteins and thereby inhibit growth of cancer cells.
Teaching methods
Language of instruction and examination
English.Recommended reading/syllabus
The lectures, seminars and the "hand outs" that are given during the course defines the curriculum.
Application deadline
Assessment
Exam and evaluation
3 oral presentations of articles (1 for each module); presented in plenary discussions.Evaluated with passed/not passed.
The three exams are evaluated separately as passed/not passed. All three parts have to be passed to pass the course. Continuation on a part/parts that is evaluated to "not passed" will be given early the following semester.
Work requirements
Lectures and seminars are obligatory.
Continuation exam
Continuation exam is given early in the following semester.
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