Bioinformatics: Genomes and genomics

Bioinformatics is a combination of biological science and information technology used in analyzing and deriving conclusions from large data sets. This course introduces the students to bacterial genomes and genome analysis. Genome-scale sequencing projects have led to an explosion of genetic information (gene sequences) available for analysis. The student will be shown how these sequences can lead to a much fuller understanding of many biological processes. The aim is to provide a practical description of the topics, tools and current trends in bacterial genomics including their impact on biology, human and veterinary medicine. Major topics will include:

• genome sequencing and assembly
• genome annotation (gene prediction and functional assignment)
• prediction of binding sites
• comparative genomics
• Transcriptomics (RNA-seq)

-    systems biology -    phylogenetic analysis  

Knowledge:

The candidate:

• has broad knowledge in genomics and genome analysis including
• is familiar with methods and techniques applied in bioinformatics on prokaryote organisms
• can apply bioinformatics to important areas of this field
• can update his/her knowledge related to comparative genomics

Skills: The candidate:

• can evaluate  information in bioinformatics and use it to work with practical and theoretical problems
• can analyse methods, techniques and interpretations in bioinformatics and work independently on practical problems
• can use relevant methods and techniques in bioinformatics based on well-founded choises
• can carry out a  limited research project under supervision.

General competence: The candidate:

• can apply her/his knowledge and skills in bioinformatics in order to carry out assignments and projects
• can communicate terminology in the field of bioinformatics
• can communicate about academic issues, analyses and conclusions in the field of bioinformatics

If you pass the examination in this course, you will get an reduction in credits (as stated below), if you previously have passed the following courses:

• KJE-8602 Bioinformatics - genome and genome analysis 8 stp

Language of instruction and examination

Evaluation of orally presented report. Pass/not pass.

Candidates who fail the exam can register for re-sit the following semester.