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Bilde av Hansen, Jørn H
Bilde av Hansen, Jørn H
Professor Department of Chemistry jorn.h.hansen@uit.no +4777645992 40768633 You can find me here

Jørn H Hansen

Job description

Professor of Organic Synthesis/Medicinal Chemistry

UiT Merited Teacher

Head of the Chemical Synthesis and Analysis Group

  • Sindhu Kancherla, Jørn Hedløy Hansen :
    Synthesis of Cryptophanes: Recent Advances
    European Journal of Organic Chemistry 2024 ARKIV / DOI
  • Vijayaragavan Elumalai, Tomaz Trobec, Maja Grundner, Christophe Labriere, Robert Frangez, Kristina Sepcic et al.:
    Development of potent cholinesterase inhibitors based on a marine pharmacophore
    Organic and biomolecular chemistry 2022 ARKIV / DOI
  • Aya Ismael, Muhammad Zeeshan, Jørn H Hansen :
    Synthesis of aromatic lactone analogues of Lipoxin A4
    BMC Research Notes 2022 ARKIV / DOI
  • Vijayaragavan Elumalai, Jørn H Hansen :
    Synthesis of 5,7-diarylindoles via Suzuki-Miyaura coupling in water
    Organic and biomolecular chemistry 2021 ARKIV / DOI
  • Lotta Turunen, Jørn H Hansen, Máté Erdélyi :
    Halogen Bonding: An Odd Chemistry?
    The chemical record 2021 FULLTEKST / ARKIV / DOI
  • Christophe Labriere, Gunnar Cervin, Henrik Pavia, Jørn H Hansen, Johan Svenson :
    Structure–Activity Relationship Probing of the Natural Marine Antifoulant Barettin
    Marine Biotechnology 2021 DOI
  • Vijayaragavan Elumalai, Jørn H Hansen :
    A Green, Scalable, and Catalyst-Free One-Minute Synthesis of Quinoxalines
    SynOpen 2021 ARKIV / DOI
  • Christophe Labriere, Vijayaragavan Elumalai, Jannie Staffansson, Gunnar Cervin, Tiffany Le Norcy, Hugo Denardou et al.:
    Phidianidine A and Synthetic Analogues as Naturally Inspired Marine Antifoulants
    Journal of natural products 2020 ARKIV / DOI
  • Vijayaragavan Elumalai, Jørn H Hansen :
    A scalable and green one-minute synthesis of substituted phenols
    RSC Advances 2020 ARKIV / DOI
  • Tone Kristoffersen, Vijayaragavan Elumalai, Eliot Starck, Étienne Cousin, Lucille J. Wagner, Stephanie Ramona Hansen et al.:
    Microwave‐Assisted Synthesis of Heterocycles from Aryldiazoacetates
    European Journal of Organic Chemistry 2020 ARKIV / FULLTEKST / DATA / DOI
  • Vijayaragavan Elumalai, Jørn H Hansen :
    A Green, Scalable, One-Minute Synthesis of Benzimidazoles
    Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry 2020 ARKIV / DOI
  • Roberto Bartholomeus Wilhelmus Bekker, Richard Fjellaksel, Trine Hjornevik, Syed Nuruddin, Waqas Rafique, Jørn H Hansen et al.:
    Discovery of a lead brain-penetrating gonadotropin-releasing hormone receptor antagonist with saturable binding in brain
    ChemMedChem 2020 ARKIV / DOI
  • T. W. Zewde, Dejene Kifle, Jostein a Johansen, Taye Beyene Demissie, Jørn H Hansen, Zenebe Tadesse :
    Cyanobacterial abundance and microcystins in water, seston and fish tissues in Lake Hora-Arsedi (Ethiopia)
    African Journal of Aquatic Science 2020 DOI
  • Jørn H Hansen, Richard Fjellaksel :
    Catalytic Intermolecular Functionalization of Benzimidazoles
    IntechOpen 2019 DOI
  • Samson Tilahun, Demeke Kifle, Tigist W Zewde, Jostein a Johansen, Taye Beyene Demissie, Jørn H Hansen :
    Temporal dynamics of intra-and extra-cellular microcystins concentrations in Koka reservoir (Ethiopia): Implications for public health risk
    Toxicon 2019 ARKIV / DOI
  • Richard Fjellaksel, Angel Moldes-Anaya, Terje Vasskog, Ana Oteiza, Maria Montserrat Martin-Armas, Ole Kristian Hjelstuen et al.:
    Evaluation by metabolic profiling and in vitro autoradiography of two promising GnRH‐receptor ligands for brain SPECT imaging
    Journal of labelled compounds & radiopharmaceuticals 08. December 2019 ARKIV / DOI
  • Christophe Labriere, Jeanette hammer Andersen, Marte Albrigtsen, Jørn H Hansen, Johan Svenson :
    Heterocyclic cellular lipid peroxidation inhibitors inspired by the marine antioxidant barettin
    Bioorganic chemistry (Print) 2018 ARKIV / DOI
  • Christophe Labriere, Nahid Kondori, Josefin Seth Caous, Marc Boomgaren, Kerstin Sandblom, Kristina Nilsson-Ekdahl et al.:
    Development and Evaluation of Cationic Amphiphilic Antimicrobial 2,5-Diketopiperazines
    Journal of Peptide Science 2018 DOI
  • Tigist W Zewede, Jostein a Johansen, Demeke Kifle, Taye Beyene Demissie, Jørn H Hansen, Zenebe Tadesse :
    Concentrations of microcystins in the muscle and liver tissues of fish species from Koka reservoir, Ethiopia: A potential threat to public health
    Toxicon 2018 DOI
  • Richard Fjellaksel, Ana Oteiza, Montserrat Martin-Armas, Patrick Riss, Ole Kristian Hjelstuen, Samuel Kuttner et al.:
    First in vivo evaluation of a potential SPECT brain radiotracer for the gonadotropin releasing hormone receptor
    BMC Research Notes 2018 ARKIV / DOI
  • Richard Fjellaksel, Damir Dugalic, Taye Beyene Demissie, Patrick Riss, Ole Kristian Hjelstuen, Rune Sundset et al.:
    An acylation-Finkelstein approach to radioiodination of bioactives: The role of amide group anchimeric assistance
    Journal of Physical Organic Chemistry 2018 FULLTEKST / ARKIV / DOI
  • Richard Fjellaksel, Rune Sundset, Patrick Riss, Jørn H Hansen :
    Copper-mediated late-stage iodination and 123I-labelling of triazole-benzimidazole bioactives
    Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry 2018 DOI
  • Tone Kristoffersen, Jørn H Hansen :
    3,4-Dihydroquinoxalin-2-ones: recent advances in synthesis and bioactivities
    Chemistry of Heterocyclic Compounds 2017 ARKIV / DOI
  • Richard Fjellaksel, Marc Boomgaren, Rune Sundset, Ira Hebold Haraldsen, Jørn H Hansen, Patrick Riss :
    Small molecule piperazinyl-benzimidazole antagonists of the gonadotropin-releasing hormone (GnRH) receptor
    MedChemComm 2017 ARKIV / DOI
  • Uranbaatar Erdenebileg, Taye Beyene Demissie, Jørn H Hansen :
    Visible-Light Photocatalytic Double C-H Functionalization of Indoles: A Synergistic Experimental and Computational Study
    Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry 2017 ARKIV / DOI
  • Taye Beyene Demissie, Kenneth Ruud, Jørn H Hansen :
    Cryptophanes for Methane and Xenon Encapsulation: A Comparative Density Functional Theory Study of Binding Properties and NMR Chemical Shifts
    Journal of Physical Chemistry A 2017 ARKIV / DOI
  • Yansong Zhao, Jørn H Hansen, Tobias Boström :
    Extraction of magnetic nanoparticles using magnetic ionic liquids
    Micro & Nano Letters 2016 DOI
  • Taye Beyene Demissie, Jørn H Hansen :
    Synergy between Experimental and Computational Approaches to Homogeneous Photoredox Catalysis
    Dalton Transactions 2016 ARKIV / DOI
  • Taye Beyene Demissie, Jørn H Hansen :
    Mechanism and Site-Selectivity in Visible-Light Photocatalyzed C–H Functionalization: Insights from DFT Calculations
    Journal of Organic Chemistry 2016 DOI
  • Jørn Hedløy Hansen, Annette Bayer, Marius Myreng Haugland :
    Enhanced teaching and learning outcomes from restructuring a basic organic chemistry course
    Nordic Journal of STEM Education 2023 ARKIV / FULLTEKST
  • Hanna Bähr, Karoline Nordli, Jørn Hedløy Hansen :
    Synthesis of a medetomidine analogue library for antifouling testing
    2023
  • Karoline Nordli, Hanna Bähr, Mathias Kranz, Angel Moldes-Anaya, Jørn H Hansen :
    Towards a Novel Radiotracer for PET – Imaging of Glioblastoma Targeting the Notch Signaling Pathway
    2023
  • Karoline Nordli, Hanna Bähr, Angel Moldes-Anaya, Jørn H Hansen, Mathias Kranz :
    Towards a novel radiotracer for PET – imaging of glioblastoma targeting the Notch signaling pathway
    2022
  • Hanna Bähr, Jørn Hedløy Hansen :
    Streamlined synthesis of GnRH-R binders and late-stage functionalization
    2020
  • T. W. Zewde, Jostein a Johansen, Demeke Kifle, Taye Beyene Demissie, Jørn H Hansen, Zenebe Tadesse :
    Erratum: ‘Corrigendum to “” [ <153> (<2018>) <85–95>](S0041010118303593)(10.1016/j.toxicon.2018.08.013)
    Toxicon 2019 DOI
  • Uranbaatar Erdenebileg, Jørn H Hansen :
    Selective Photocatalytic Bromination of Indoles
    2018
  • Tone Kristoffersen, Eliot Starck, Stephanie Ramona Hansen, Lucille Wagner, Jørn H Hansen :
    Microwave-assisted synthesis of heterocycles from aryldiazoacetates
    2018
  • Richard Fjellaksel, Ana Oteiza, armas maria montserrat Martin, Jørn H Hansen, Angel Moldes-Anaya, Terje Vasskog et al.:
    Development and evaluation of gonadotropin releasing hormone SPECT radioligands
    2018 DATA
  • Mukesh Yadav, Jana Jágerská, Jørn H Hansen, Olav Gaute Hellesø :
    Sensitivity and response time of an on-chip methane sensor
    2017
  • Jana Jágerská, Firehun Tsige Dullo, Susan M. Lindecrantz, Jacqueline Boergers, Jørn H Hansen, Laura Gomez Lechuga et al.:
    Cryptophane-Cladded Interferometric Waveguide Sensor for Aqueous Methane Detection
    2017
  • Uranbaatar Erdenebileg, Taye Beyene Demissie, Jørn H Hansen :
    Visible-light photocatalytic C-H functionalization of heterocycles
    2017
  • Marc Boomgaren, Birta Ravdna Sarre, Tor Arne Heim Andberg, Bjørn Olav Brandsdal, Johan Isaksson, Jørn H Hansen :
    Synthesis and exploration of a novel molecular scaffold for dUTPase inhibition: Aiming for new anticancer agents
    2017
  • Richard Fjellaksel, Jørn H Hansen, Angel Moldes-Anaya, armas maria montserrat Martin, Ana Oteiza, Patrick Riss et al.:
    Development and evaluation of gonadotropin releasing hormone (GnRH) SPECT radioligands
    2017 FULLTEKST / DATA
  • Martin Ingvaldsen, Jana Jágerská, Firehun Tsige Dullo, Susan M. Lindecrantz, Magnus Engqvist, Jørn H Hansen et al.:
    Cryptophane-A doped polymers for methane sensing
    2016
  • Jana Jágerská, Firehun Tsige Dullo, Martin Ingvaldsen, Susan M. Lindecrantz, Magnus Engqvist, Jørn H Hansen et al.:
    On-chip methane sensors based on cryptophane-A cladded waveguide interferometers
    2016
  • Jana Jágerská, Firehun Tsige Dullo, Martin Ingvaldsen, Susan M. Lindecrantz, Magnus Engqvist, Jørn H Hansen et al.:
    On-Chip Methane Sensing with Cryptophane-A Cladded Waveguide Interferometers
    2016
  • Jana Jágerská, Firehun Tsige Dullo, Martin Ingvaldsen, Susan M. Lindecrantz, Jørn H Hansen, Stian Solbø et al.:
    On-chip methane sensing with a cryptophane-A cladded Mach-Zehnder interferometer
    2016
  • Damir Dugalic, Richard Fjellaksel, Marc Boomgaren, Ole Kristian Hjelstuen, Jørn H Hansen :
    Development and validation of gonadotropin releasing hormone receptor SPECT/PET radioligands
    2016
  • Tone Kristoffersen, Eline Samuelsen, Phenias Buhire, Lisa Ramstad, Ane Molden, Taye Beyene Demissie et al.:
    Diverse libraries for chemoprospecting and chemical education
    2016
  • Aya Ismael, Muhammad Zeeshan, Jørn H Hansen :
    Novel Synthesis of Lipoxin A4 Analogues
    2016

    • The 50 latest publications is shown on this page. See all publications in Cristin here →

    Publications outside Cristin

    1. Li, Z.; Boyarskikh, V.; Hansen, J. H.; Musaev, D.; Autschbach, J.; Davies, H. M. L. J. Am. Chem. Soc., 2012,134, 15497.
    2. Hansen, S. R.; Spangler, J.; Hansen, J. H.; Davies, H. M. L. Org. Lett., 2012, 14, 4626.
    3. Qin, C.; Boyarskikh, V.; Hansen, J. H.; Musaev, D. G.; Davies, H. M. L. J. Am. Chem. Soc.,2011, 133, 19198.
    4. Ovalles, S. R.; Hansen, J. H.; Davies, H. M. L. Org. Lett. 2011,13, 4284-4287
    5. Hansen, J. H.; Gregg, T. M.; Ovalles, S. R.; Lian, Y.; Autschbach, J.; Davies, H. M. L. J. Am. Chem. Soc. 2011, 133, 5076-5085.
    6. Hansen, J. H.; Parr, B. T.; Pelphrey, P.; Jin, Q.; Autschbach, J.; Davies, H. M. L. Angew. Chem., Int. Ed., 2011, 50, 2544-2548.
    7. Hansen, J. H.; Davies, H. M. L. Chem. Sci. 2010, 2, 457-461.
    8. Briones, J.F.; Hansen, J. H.;Hardcastle, K.; Autschbach, J.; Davies, H. M. L. J. Am. Chem. Soc., 2010, 132, 17211.
    9. Pelphrey, P.; Hansen, J.; Davies, H. M. L. Chem. Sci. 2010, 1, 254.
    10. Davies, H. M. L.; Hansen, J. Book chapter in: Catalytic Asymmetric Synthesis 3rd ed. (Ed. Ojima, I.) 2010, p. 163-226.
    11. Hansen, J.; Li, B.; Autschbach, J.; Dikarev, E. V.; Davies, H. M. L. J. Org. Chem. 2009, 74, 6564-6571.
    12. Hansen, J.; Autschbach, J.; Davies, H. M. L. J. Org. Chem. 2009, 74, 6555-6563.
    13. Sevryugina, Y.; Weaver, B.; Hansen, J.; Thompson, J.; Davies, H. M. L.; Petrukhina, M. A. Organometallics 2008, 27, 1750-1757.
    14. Hansen, J., Davies, H. M. L. Coord. Chem. Rev. 2008, 252, 545-555.

    Research interests

     1. Bioactive heterocycles

    2. Photo- and transition metal catalysis

    3. Late-Stage Functionalization

    4. Small-molecule PET-radiopharmaceuticals

    5. Molecular sensing

    Teaching

    KJE-2003 Introduction to Analytical Chemistry

    KJE-3314 Organic Chemistry II: Reactions and selectivity

    KJE-3308/8308 Metal-organic Compounds in Organic Synthesis (biennial)

    ORCID: 0000-0002-3888-5217

    Member of research group

    Chemical Synthesis and Analysis   English content KjemDiA   Norsk innhold

    Member of project

    SusSTEMEd: Center for Sustainable STEM Education    English content

    CV

     

    EDUCATION

    2010

    Ph.D. – Organic Chemistry

    Emory University, Atlanta, GA, USA (Davies Group)

    University at Buffalo, The State University of New York (Davies Group)

    2005

     

    M.Sc./Sivilingeniør  –  Chemistry and Biotechnology,

    Norwegian University of Science and Technology (NTNU) (Carlsen Group)

    PROFESSIONAL EXPERIENCE

    2012–2022

    Associate Professor, University of Tromsø, Norway

    2012

    		 Visiting Assistant Professor, Touro College, Manhattan, New York City.
    2010-2012 Postdoctoral Research Associate, Princeton University (MacMillan Group)
    2005-2007 Teaching Assistant, University at Buffalo, The State University of New York