Espen Holst Hansen
Job description
Professor in marine biotechnology
Deputy head of research, Norwegian College of Fishery Sciences (NCFS)
Jon Brage Svenning,
Terje Vasskog,
Karley Lynn Campbell,
Agnethe Hansen Bæverud,
Torbjørn Norberg Myhre,
Lars Dalheim
et al.:
Lipidome Plasticity Enables Unusual Photosynthetic Flexibility in Arctic vs. Temperate Diatoms
Yannik Karl Heinz Schneider,
Anton Liaimer,
Johan Mattias Isaksson,
Oda Sofie Bye Wilhelmsen,
Jeanette Hammer Andersen,
Kine Østnes Hansen
et al.:
Four new suomilides isolated from the cyanobacterium Nostoc sp. KVJ20 and proposal of their biosynthetic origin
Giovanna Romano,
Mariana Almeida,
Ana Varela Coelho,
Adele Cutignano,
Lous G Goncalves,
Espen Holst Hansen
et al.:
Biomaterials and Bioactive Natural Products from Marine Invertebrates: From Basic Research to Innovative Applications
Hans Christian Eilertsen,
Gunilla Eriksen,
John-Steinar Bergum,
Jo Strømholt,
Edel O. Elvevoll,
Karl-Erik Eilertsen
et al.:
Mass Cultivation of Microalgae: I. Experiences with Vertical Column Airlift Photobioreactors, Diatoms and CO2 Sequestration
Yannik Karl Heinz Schneider,
Ole Christian Hagestad,
Chun Li,
Espen Holst Hansen,
Jeanette Hammer Andersen
:
Selective isolation of Arctic marine actinobacteria and a down-scaled fermentation and extraction strategy for identifying bioactive compounds
Fazlin Pheiffer,
Yannik Karl Heinz Schneider,
Espen Holst Hansen,
Jeanette Hammer Andersen,
Johan Mattias Isaksson,
Tobias Busche
et al.:
Bioassay-Guided Fractionation Leads to the Detection of Cholic Acid Generated by the Rare Thalassomonas sp.
Venke Kristoffersen,
Marte Jenssen,
Heba Raid Jawad,
Johan Isaksson,
Espen Hansen,
Teppo Rämä
et al.:
Two Novel Lyso-Ornithine Lipids Isolated from an Arctic Marine Lacinutrix sp. Bacterium
Kine Østnes Hansen,
Ida Kristine Østnes Hansen,
Céline Sarah Marine Richard,
Marte Jenssen,
Jeanette Hammer Andersen,
Espen Holst Hansen
:
Antimicrobial Activity of Securamines From the Bryozoan Securiflustra securifrons
Renate Døving Osvik,
Jeanette Hammer Andersen,
Hans Christian Eilertsen,
Anne-Marie Genevière,
Espen Holst Hansen
:
Bioactivity of a Marine Diatom (Porosira glacialis [Grunow] Jorgensen 1905) Cultivated With and Without Factory Smoke CO2
Hans Christian Eilertsen,
Edel O. Elvevoll,
Ingeborg Hulda Giæver,
Jon Brage Svenning,
Lars Dalheim,
Ragnhild Aven Svalheim
et al.:
Inclusion of photoautotrophic cultivated diatom biomass in salmon feed can deter lice
Ole Christian Hagestad,
Lingwei Hou,
Jeanette Hammer Andersen,
Espen Hansen,
Bjørn Altermark,
Chun Li
et al.:
Genomic characterization of three marine fungi, including Emericellopsis atlantica sp. nov. with signatures of a generalist lifestyle and marine biomass degradation
Marte Jenssen,
Venke Kristoffersen,
Kumar Motiram-Corral,
Johan Isaksson,
Teppo Rämä,
Jeanette Hammer Andersen
et al.:
Chlovalicin B, a Chlorinated Sesquiterpene Isolated from the Marine Mushroom Digitatispora marina
Yannik Karl-Heinz Schneider,
Solveig Jørgensen,
Jeanette Hammer Andersen,
Espen Hansen
:
Qualitative and quantitative comparison of liquid–liquid phase extraction using ethyl acetate and liquid–solid phase extraction using poly-benzyl-resin for natural products
Marte Jenssen,
Philip Rainsford,
Eric Juskewitz,
Jeanette Hammer Andersen,
Espen Hansen,
Johan Isaksson
et al.:
Lulworthinone, a New Dimeric Naphthopyrone From a Marine Fungus in the Family Lulworthiaceae With Antibacterial Activity Against Clinical Methicillin-Resistant Staphylococcus aureus Isolates
Renate Døving Osvik,
Richard Andre Ingebrigtsen,
Fredrika Norrbin,
Jeanette Hammer Andersen,
Hans Christian Eilertsen,
Espen Holst Hansen
:
Adding zooplankton to the OSMAC toolkit: Effect of grazing stress on the metabolic profile and bioactivity of a diatom
Chiara Lauritano,
Kirsti Helland,
Gennaro Riccio,
Jeanette Hammer Andersen,
Adrianna Ianora,
Espen Holst Hansen
:
Lysophosphatidylcholines and Chlorophyll-Derived Molecules from the Diatom Cylindrotheca closterium with Anti-Inflammatory Activity
Yannik Karl-Heinz Schneider,
Marte Jenssen,
Johan Isaksson,
Kine Østnes Hansen,
Jeanette Hammer Andersen,
Espen Hansen
:
Bioactivity of Serratiochelin A, a Siderophore Isolated from a Co-Culture of Serratia sp. and Shewanella sp.
Jørgen A Mølmann,
Espen Holst Hansen,
Tor Jacob Johansen
:
Effects of supplemental LED light quality and reduced growth temperature on swede (Brassica napus L. ssp. rapifera Metzg.) root vegetable development and contents of glucosinolates and sugars
Philip Brennecke,
Dace Rasina,
Oscar Aubi Catevilla,
Katja Herzog,
Johannes Landskron,
Bastien Cautain
et al.:
EU-OPENSCREEN: A novel collaborative approach to facilitate chemical biology
Raja Priyanka Mary Michael Siranjeevi,
Espen Hansen,
Johan Isaksson,
Jeanette hammer Andersen,
Kine Østnes Hansen
:
Dendrobeaniamine A, a new alkaloid from the Arctic marine bryozoan Dendrobeania murrayana
Ole Christian Hagestad,
Jeanette hammer Andersen,
Bjørn Altermark,
Espen Hansen,
Teppo Rämä
:
Cultivable marine fungi from the Arctic Archipelago of Svalbard and their antibacterial activity
Kine Østnes Hansen,
Jeanette hammer Andersen,
Annette Bayer,
Sunil Kumar Pandey,
Marianne Lorentzen,
Kåre Bredeli Jørgensen
et al.:
Kinase chemodiversity from the Arctic: the breitfussins
Espen Holst Hansen
:
MARINE BIOPROSPECTING WITH AN ARCTIC PERSPECTIVE: THE MARBIO SCREENING PLATFORM AND ITS INVOLVEMENT IN LARGER EUROPEAN PROJECTS
2023
Espen Holst Hansen,
Kine Østnes Hansen,
Jeanette Hammer Andersen
:
HotBio - a Horizon Europe MSCA Doctoral Network in Marine Biodiscovery
2023
Magnus Andersland Antonsen,
Kine Østnes Hansen,
Espen Holst Hansen,
Terje Vasskog
:
Use of metabolomics to identify secondary metabolites from marine algae biomass
2023
Marit Huizer,
Kristine Haugland,
Agnethe Hansen Bæverud,
Jon Brage Svenning,
Kine Østnes Hansen,
Espen Holst Hansen
et al.:
LC-Orbitrap MS/MS based untargeted lipidomics of marine microalgae
2023
Yannik Karl Heinz Schneider,
Anton Liaimer,
Johan Mattias Isaksson,
Oda Sofie Bye Wilhelmsen,
Jeanette Hammer Andersen,
Kine Østnes Hansen
et al.:
Corrigendum: Four new suomilides isolated from the cyanobacterium Nostoc sp. KVJ20 and proposal of their biosynthetic origin (Frontiers in Microbiology, (2023), 14, (1130018), 10.3389/fmicb.2023.1130018)
Frontiers in Microbiology 2023 DOI
Guillaume Petit,
Kine Østnes Hansen,
Jeanette Hammer Andersen,
Espen Holst Hansen,
Annette Bayer,
Bengt Erik Haug
et al.:
A fragment to bind them all: Characterising phorbazole fragments as pan-kinase inhibitor
2023
Espen Holst Hansen
:
Discovery of new antibacterial compounds from the Arctic Ocean
2023
Espen Holst Hansen
:
Fra havets bunn til sykehuset
Fiskeribladet 2023 ARKIV
Yannik Karl Heinz Schneider,
Jeanette Hammer Andersen,
Espen Holst Hansen
:
Conference-presentation about bioactivity screening and the SuReMetS Project at the seminar for Enzymatic protein hydrolysis and Bioactive peptides
2022
Yannik Karl Heinz Schneider,
Jeanette Hammer Andersen,
Espen Holst Hansen
:
Marine rest-rawmaterials for health – how to increase the value of by-products?
2022
Espen Holst Hansen
:
Marbio - A platform for marine natural products drug discovery
2021
Yannik Karl-Heinz Schneider,
Njål Rauø,
Espen Holst Hansen,
Jeanette Hammer Andersen,
Jascha MacDonald,
Wolfgang R. Streit
et al.:
The SuReMetS-project - From sustainable resources to novel marine
nutraceuticals for the management of metabolic syndrome
2021
Yannik Karl Heinz Schneider,
Jeanette Hammer Andersen,
Espen Holst Hansen
:
Presentation at the Biotech-North and Cod-Cluster about the metabolic syndrome, SuReMetS project and screening of rest-raw material.
2021
Anette Hustad,
Birthe Vang,
Hans Christian Eilertsen,
Sten Ivar Siikavuopio,
Bjørn-Steinar Sæther,
Ragnhild Aven Svalheim
et al.:
Mikroalger i fôr, ny løsning for å redusere lusepåslag på laks – Faglig sluttrapport
2020 ARKIV
Espen Holst Hansen,
Jeanette hammer Andersen
:
Molekylet som kan stoppe brystkreft
07. January 2020
Espen Holst Hansen,
Kine Østnes Hansen,
Jeanette hammer Andersen
:
Nye legemidler fra havet?
Dagens næringsliv 04. January 2020 FULLTEKST
Espen Hansen
:
Cutting-Edge Analytical Technology Advances Arctic Marine Bioprospecting
06. March 2019
Espen Hansen
:
Natural Product Drug Discovery From Marine Organisms With Advanced UPLC and MS Technology
2019 FULLTEKST
Priyanka Michael,
Espen Hansen,
Johan Isaksson,
Jeanette hammer Andersen,
Kine Østnes Hansen
:
Dendrobeaniamine A, a New Alkaloid from the Arctic Marine bryozoan Dendrobeania murrayana
2019
Marte Jenssen,
Teppo Rämä,
Kine Ø. Hanssen,
Venke Kristoffersen,
Espen Hansen,
Jeanette hammer Andersen
:
Exploring the chemical and biological potential of Arctic marine fungi
2019
Renate Døving Osvik,
Espen Hansen,
Hans Christian Eilertsen,
Anne-Marie Genevière
:
Extract of a marine diatom negatively affects development in sea urchin (Paracentrotus lividus) embryos
2019
Yannik Karl-Heinz Schneider,
Espen Hansen
:
Quantitative comparison of solid and liquid phase extraction of natural products from bacterial fermentations
2019
Marte Jenssen,
Jeanette Hammer Andersen,
Teppo Rämä,
Espen Holst Hansen,
Kine Østnes Hansen,
Chun Li
:
Biodiscovery of Antimicrobial Compounds from Arctic Marine Microorganisms
2019
Espen Hansen
:
Good prospects
European Laboratory Technology 2019 FULLTEKST
Kine Ø. Hanssen,
Jeanette hammer Andersen,
Bert Klebl,
Jan Eickhoff,
Johan Isaksson,
Espen Hansen
:
Novel kinase inhibitors from the Arctic marine hydrozoan Thuiaria breitfussi
2019
Espen Hansen
:
Novel kinase inhibitors from the Arctic marine hydrozoan Thuiaria breitfussi
2019
Espen Hansen
:
Use of ion mobility in mass spectrometry-based metabolomics of marine natural products
2019
Espen Hansen
:
Marine bioprospecting - The search for bioactive compounds of scientific and commercial interest in the marine environment
2019
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Research interests
I am responsible for the chemical characterisation of bioactive secondary metabolites in Marbio.
The tools I use in the laboratory includes:
- Mass spectrometry (MS), both quadropoles and high-resolution (HR) systems
- Ion mobility spectrometry (IMS)
- Chromatography, including low pressure (Flash) as well as both HPLC and UHPLC
I use these tools to isolate and characterize bioactive secondary metabolites through the following workflows:
- Extraction and prefractionation of biological material
- Dereplication of bioactive extracts and fractions using UHPLC-IMS-HR-MS
- Metabolic profiling and metabolomics
- Mass guided fractionation using HPLC
Member of research group
Attachments:
- Waters Marbio Case study (pdf)