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Bilde av Fenton, Christopher Graham
Bilde av Fenton, Christopher Graham
PhD, Senior Researcher Clinical bioinformatics christopher.fenton@uit.no Tromsø You can find me here

Christopher Graham Fenton

Job description

Bioinformatition at the Computational Biollogy Research Group. 

 

  • 1
    Jing Yan, Jiazheng Cai, Xiaojing Pan, Si Li, Christopher Graham Fenton, Kristin Andreassen Fenton et al.:
    Resolvin D1 Modulates the Inflammatory Processes of Human Periodontal Ligament Cells via NF-κB and MAPK Signaling Pathways
    Biomedicines 10. December 2025 DOI / ARKIV
  • 1
    Leon Cantas, Christopher Graham Fenton, Emese Bato, Ruth H Paulssen, Henning Sørum :
    Impact of antibiotic choice on immune response and antibiotic resistance development in piglets experimentally infected with Escherichia coli
    Frontiers in Cellular and Infection Microbiology 09. September 2025 DOI / ARKIV
  • 1
    Leon Cantas, Rasmus Goll, Christopher Graham Fenton, Ruth Erika Hildegard Hracky Paulssen, Henning Sørum :
    Impact of fecal microbiota transplantation in dogs
    Frontiers in Veterinary Science 2025 DOI / ARKIV
  • 1
    Line Strand Karlsholm, Rafi Ahmad, Hagar Taman, Christopher Graham Fenton, Ruth H Paulssen :
    Actively expressed microbiota in mucosal biopsies of treatment-naïve ulcerative colitis patients
    Gut Microbes Reports 2025 DOI / ARKIV
  • 1
    Christopher Graham Fenton, Mithlesh Kumar Ray, Ruth Erika Hildegard Hracky Paulssen :
    Challenges in Defining a Reference Set of Differentially Expressed lncRNAs in Ulcerative Colitis by Meta-Analysis
    Current Issues in Molecular Biology 2024 DOI / ARKIV
  • 1
    Wei Meng, Christopher Graham Fenton, Kay-Martin Johnsen, Hagar Taman, Jon Florholmen, Ruth Erika Hildegard Hracky Paulssen :
    DNA methylation fine-tunes pro-and anti-inflammatory signalling pathways in inactive ulcerative colitis tissue biopsies
    Scientific Reports 2024 DOI / ARKIV
  • 1
    Alicia Villatoro, Vincent Cuminetti, Aurora Bernal Mera, Carlos Torroja, Itziar Cossío, Alberto Benguría et al.:
    Endogenous IL-1 receptor antagonist restricts healthy and malignant myeloproliferation
    Nature Communications 2023 DOI / ARKIV
  • 1
    Wei Meng, Kay-Martin Johnsen, Christopher Graham Fenton, Jon Florholmen, Ruth H Paulssen :
    Anti-apoptotic genes and non-coding RNAs are potential outcome predictors for ulcerative colitis
    Functional & Integrative Genomics 2023 DOI / ARKIV
  • 1
    Christopher Graham Fenton, Mithlesh Kumar Ray, Wei Meng, Ruth H Paulssen :
    Methylation-Regulated Long Non-Coding RNA Expression in Ulcerative Colitis
    International Journal of Molecular Sciences 2023 DOI / ARKIV
  • 1
    Amrinder Singh, Christopher Graham Fenton, Endre Anderssen, Ruth H Paulssen :
    Identifying predictive signalling networks for Vedolizumab response in ulcerative colitis
    International Journal of Colorectal Disease 11. May 2022 DOI / ARKIV
  • 1
    Mithlesh Kumar Ray, Christopher Graham Fenton, Ruth H Paulssen :
    Novel long non-coding RNAs of relevance for ulcerative colitis pathogenesis
    Non-coding RNA Research 2022 DOI / ARKIV
  • 1
    Amrinder Singh, Endre Anderssen, Christopher Graham Fenton, Ruth H Paulssen :
    Identifying anti-TNF response biomarkers in ulcerative colitis using a diffusion-based signalling model
    Bioinformatics Advances 2021 DOI / ARKIV
  • 1
    Eva-Stina Isabella Edholm, Christopher Graham Fenton, Stanislas Mondot, Ruth H Paulssen, Marie-Paule Lefranc, Pierre Boudinot et al.:
    Profiling the T Cell Receptor Alpha/Delta Locus in Salmonids
    Frontiers in Immunology 28. October 2021 DOI / ARKIV
  • 1
    Hagar Taman, Christopher Graham Fenton, Endre Anderssen, Jon Florholmen, Ruth H Paulssen :
    DNA hypo-methylation facilitates anti-inflammatory responses in severe ulcerative colitis
    PLOS ONE 2021 DOI / ARKIV
  • 1
    Seyed Esmaeil Dorraji, Premasany Kanapathippillai, Aud-Malin Karlsson Hovd, Mikael Ryan Stenersrød, Kjersti Daae Horvei, anita Ursvik et al.:
    Kidney tertiary lymphoid structures in Lupus Nephritis develop into large interconnected networks and resemble lymph nodes in gene signature
    American Journal of Pathology 2020 DOI / ARKIV
  • 1
    Christopher Graham Fenton, Hagar Taman, Jon Florholmen, Sveinung Sørbye, Ruth H Paulssen :
    Transcriptional signatures that define ulcerative colitis in remission
    Inflammatory Bowel Diseases 2020 DOI / ARKIV
  • 1
    Christian Børde Arkteg, Rasmus Goll, Mona Dixon Gundersen, Endre Anderssen, Christopher Graham Fenton, Jon Florholmen :
    Mucosal gene transcription of ulcerative colitis in endoscopic remission
    Scandinavian Journal of Gastroenterology 2020 DOI / ARKIV
  • 1
    Mona Dixon Gundersen, Rasmus Goll, Christopher Graham Fenton, Endre Anderssen, Sveinung Wergeland Sørbye, Jon Florholmen et al.:
    Fibrosis Mediators in the Colonic Mucosa of Acute and Healed Ulcerative Colitis
    Clinical and Translational Gastroenterology 2019 DOI / ARKIV
  • 1
    Stine Figenschau, Erik Knutsen, Ilona Urbarova, Christopher Graham Fenton, Bryan Elston, Maria Perander et al.:
    ICAM1 expression is induced by proinflammatory cytokines and associated with TLS formation in aggressive breast cancer subtypes
    Scientific Reports 2018 DOI / ARKIV
  • 1
    Hagar Taman, Christopher Graham Fenton, Inga Viktoria Hensel, Endre Anderssen, Jon Florholmen, Ruth H Paulssen :
    Genome-Wide DNA Methylation in Treatment-Naïve Ulcerative Colitis
    Journal - Crohn's and Colitis Foundation of Canada 2018 DOI / ARKIV
  • 1
    Hagar Mohamed Taman, Christopher Graham Fenton, Inga Viktoria Hensel, Endre Anderssen, Jon Florholmen, Ruth H Paulssen :
    Transcriptomic Landscape of Treatment-Naïve Ulcerative Colitis
    Journal of Crohn's and Colitis 2018 DOI / ARKIV
  • 1
    Armin Schniers, Endre Anderssen, Christopher Graham Fenton, Rasmus Goll, Yvonne Pasing, Ruth H Paulssen et al.:
    The Proteome of Ulcerative Colitis in Colon Biopsies from Adults - Optimized Sample Preparation and Comparison with Healthy Controls
    PROTEOMICS - Clinical Applications 2017 DOI / ARKIV
  • 1
    Yvonne Pasing, Christopher Graham Fenton, Rolf Jorde, Ruth H Paulssen :
    Changes in the human transcriptome upon vitamin D supplementation
    Journal of Steroid Biochemistry and Molecular Biology 2017 DOI / ARKIV
  • 1
    Vasilis Sitras, Christopher Graham Fenton, Ganesh Acharya :
    Gene expression profile in cardiovascular disease and preeclampsia: A meta-analysis of the transcriptome based on raw data from human studies deposited in Gene Expression Omnibus
    Placenta 2015 DOI / ARKIV
  • 1
    Stine Linn Figenschau, Silje Fismen, Kristin Andreassen Fenton, Christopher Graham Fenton, Elin Synnøve Mortensen :
    Tertiary lymphoid structures are associated with higher tumor grade in primary operable breast cancer patients
    BMC Cancer 2015 DOI / ARKIV
  • 1
    Michele Compagno, Ole Petter Rekvig, Anders Bengtsson, Gunnar Sturfeld, Niels H. H. Heegaard, Andreas Jönsen et al.:
    Clinical phenotype associations with various types of anti-dsDNA antibodies in patients with recent onset of rheumatic symptoms. Results from a multicentre observational study
    Lupus Science and Medicine 2014 DOI / ARKIV
  • 1
    Inigo Zubiavrre Martinez, Christopher Graham Fenton, Hagar Mohamed Taman, ingvild Pettersen, Turid Hellevik, Ruth H Paulssen :
    Tumorigenic responses of Cancer-Associated Fibroblasts after ablative radiotherapy: A transcriptome-profiling study
    Journal of Cancer Therapy 2013 DOI / ARKIV
  • 1
    Karina Standahl Olsen, Christopher Graham Fenton, Livar Frøyland, Marit Waaseth, Ruth H Paulssen, Eiliv Lund :
    Plasma Fatty Acid Ratios Affect Blood Gene Expression Profiles - A Cross-Sectional Study of the Norwegian Women and Cancer Post-Genome Cohort
    PLOS ONE 2013 DOI / ARKIV
  • 1
    Premasany Kanapathippillai, Annica Hedberg, Christopher Graham Fenton, Kristin Andreassen Fenton :
    Nucleosomes contribute to increase mesangial cell chemokine expression during the development of lupus nephritis
    Cytokine 2013 DOI / ARKIV
  • 1
    Vasilis Sitras, Christopher Graham Fenton, Ruth H Paulssen, Åse Vårtun, Ganesh Acharya :
    Differences in Gene Expression between First and Third Trimester Human Placenta: A Microarray Study
    PLOS ONE 2012 DOI / ARKIV
  • 1
    Geir Åsmund Hansen, Rafi Ahmad, erik Hjerde, Christopher Graham Fenton, Nils Peder Willassen, Peik Haugen :
    Expression profiling reveals Spot 42 small RNA as a key regulator in the central metabolism of Aliivibrio salmonicida
    BMC Genomics 2012 DOI / ARKIV
  • 1
    Dhivya Thiyagarajan, Silje Fismen, Natalya Seredkina, Søren Jacobsen, Thomas Elung-Jensen, Anne-Lise Kamper et al.:
    Silencing of Renal DNaseI in Murine Lupus Nephritis Imposes Exposure of Large Chromatin Fragments and Activation of Toll Like Receptors and the Clec4e
    PLOS ONE 2012 DOI / ARKIV
  • 1
    Tom Dønnem, Christopher Graham Fenton, Kenneth Lønvik, Thomas Berg, Katrine Eklo, Sigve Andersen et al.:
    MicroRNA Signatures in Tumor Tissue Related to Angiogenesis in Non-Small Cell Lung Cancer
    PLOS ONE 2012 DOI / ARKIV
  • 1
    Annica Hedberg, Silje Fismen, Kristin Andreassen Fenton, Christopher Graham Fenton, Bjarne Østerud, Elin Mortensen et al.:
    Heparin Exerts a Dual Effect on Murine Lupus Nephritis by Enhancing Enzymatic Chromatin Degradation and Preventing Chromatin Binding in Glomerular Membranes
    Arthritis and Rheumatism 2011 DOI / ARKIV
  • 1
    Kristin Snipstad, Christopher Graham Fenton, Jørn Kjæve, Guanglin Cui, Endre Anderssen, Ruth H Paulssen :
    New specific molecular targets for radio-chemotherapy of rectal cancer
    Molecular Oncology 2010 DOI / ARKIV
  • 1
    Kristin Andreassen Fenton, Silje Fismen, Annica Hedberg, Natalya Seredkina, Christopher Graham Fenton, Elin Mortensen et al.:
    Anti-dsDNA Antibodies Promote Initiation, and Acquired Loss of Renal Dnase1 Promotes Progression of Lupus Nephritis in Autoimmune (NZBxNZW)F1 mice
    PLOS ONE 2009 DOI / ARKIV
  • 1
    Steinar Thorvaldsen, Erik Hjerde, Christopher Graham Fenton, Nils Peder Willassen :
    Molecular characterization of cold adaptation based on ortholog protein sequences from Vibrionaceae species
    Extremophiles 2007 DOI / ARKIV
  • Alicia Elena Villatoro Gonzalez, Vincent Cuminetti, Aurora Bernal Mera, Carlos Torroja, Itziar Cossío, Alberto Benguría et al.:
    Author Correction: Endogenous IL-1 receptor antagonist restricts healthy and malignant myeloproliferation (Nature Communications, (2023), 14, 1, (12), 10.1038/s41467-022-35700-9)
    Nature Communications 2023 DOI / ARKIV
  • Wei Meng, Mithlesh Kumar Ray, Christopher Graham Fenton, Endre Anderssen, Ruth H Paulssen :
    Analysis of methylation data with imputation with blocks (MethylBlocks)
    2022 ARKIV
  • Mithlesh Kumar Ray, Christopher Graham Fenton, Ruth H Paulssen :
    Novel long-coding RNAs of relevance for ulcerative colitis pathogenesis
    2022 ARKIV
  • Christopher Graham Fenton, Hagar Taman, Jon Florholmen, Ruth H Paulssen :
    Transcriptional profiling of ulcerative colitis in remission
    2019 ARKIV
  • Christopher Graham Fenton, Hagar Taman, Jon Florholmen, Ruth H Paulssen :
    Transcriptional profiling of ulcerative colitis in remission
    Journal of Crohn's and Colitis 25. January 2019 DOI / ARKIV
  • Ruth H Paulssen, Hagar Mohamed Taman, Christopher Graham Fenton, Inga Viktoria Hensel, Endre Anderssen, Jon Florholmen :
    Novel regulatory DNA methylation features of relevance for ulcerative colitis
    American Journal of Gastroenterology 2018 DOI / ARKIV
  • Ruth H Paulssen, Hagar Mohamed Taman, Christopher Graham Fenton, Inga Viktoria Hensel, Endre Anderssen, Jon Florholmen :
    Novel regulatory DNA methylation features of relevance for ulcerative colitis
    2017 ARKIV
  • Endre Anderssen, Christopher Graham Fenton :
    Integrated analysis of epigenomic and gene expression
    2017 ARKIV
  • Vasilis Sitras, Christopher Graham Fenton, Ruth H Paulssen, Åse VÅrtun, Ganesh Acharya :
    Global gene expression profiling in the first and third trimesters of normal human pregnancy
    Placenta 2011 ARKIV
  • Vasilis Sitras, Christopher Graham Fenton, Ruth H Paulssen, Åse VÅrtun, Ganesh Acharya :
    GLOBAL PLACENTAL GENE EXPRESSION PROFILING IN THE FIRST AND THIRD TRIMESTERS OF NORMAL HUMAN PREGNANCY
    Placenta 2011 ARKIV
  • Kristin Snipstad, Christopher Graham Fenton, J Kjaeve, Jørn Kjæve, Endre Anderssen, Ruth H Paulssen :
    New specific molecular targets for radiochemotherapy in colorectal cancer
    The FEBS Journal 2009 ARKIV
  • Karina Standahl Olsen, CG Fenton, Endre Anderssen, Livar Frøyland, RH Paulssen, E Lund :
    Associations between serum linolenic acid/alpha-linolenic acid ratio and blood gene expression profiles
    The FEBS Journal 2009 ARKIV
  • christopher graham Fenton, Rafi Ahmad, Gisle Sælensminde, Nils Peder Willassen :
    Envision Software Package for the Concerted Study of Biological Data
    2005 ARKIV

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    Research interests

    Bioinformatics

    Long Non-Coding RNAs 

    Ulcerative Colitis 

    Inflammation 

    System and Network Biology 

     

    Teaching

    MBI-2011-1 23H Molecular Biology - Genetics and Cell Signalling

    KJE-2004-1 23H Bioinformatics - An introduction

     MBI-1000-1 23H Biomedicine in the 21st Century

    Researcher profile in Cristin
    ORCID: https://orcid.org/my-orcid?orcid=0000-0002-9960-0967

    Member of research group

    Clinical Bioinformatics Research Group   English content

    Member of project

    Precision medicine approaches for inflammatory-driven diseases Identifying predictive signalling networks Metatranscriptomics
    MH øst L9.105B


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