Hande disputerer for ph.d.-graden i helsevitenskap og vil offentlig forsvare avhandlingen:
The effect of omega-3 polyunsaturated fatty acids supplementation on endothelial function, lipids, and inflammatory markers in heterozygous familial hypercholesterolemia. A randomized crossover trial.
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Avhandlingen er tilgjengelig her! Prøveforelesning over oppgitt emne holdes kl. 10.15, samme sted: The Role of Omega-3 Fatty Acids in Cardiac Arrhythmias. Disputasen vil bli strømmet her. The defense will be streamed here. |
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Populærvitenskapelig sammendrag av avhandlingen:
Omega-3 polyunsaturated fatty acids in cardiovascular health have been studied for decades. However, for individuals with familial hypercholesterolemia, the knowledge is limited. Additional therapies are needed as this population has an increased risk of cardiovascular disease despite statin treatment.
This thesis is based on a clinical trial conducted at Nordland Hospital in Bodø, Norway. It examines the effects of omega-3 polyunsaturated fatty acid supplements on different aspects of atherosclerosis development in a population with familial hypercholesterolemia.
We found no effect from omega-3 polyunsaturated fatty acid supplements on endothelial function or inflammatory markers. Still, reductions in low-density lipoprotein cholesterol and triglyceride levels were observed. Based on our findings, routine recommendation of omega-3 polyunsaturated fatty acid supplements for individuals with FH is not warranted.
Hovedveileder
Professor Knut Tore Lappegård, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet.
Bedømmelseskomite
Professor emeritus Erik Berg Schmidt, Aalborg universitet– 1. opponent.
Professor Peder Langeland Myhre, Rikshospitalet/Universitet i Oslo– 2. opponent.
Førsteamanuensis Stine Andreasen, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet – leder av komite.
Disputasleder: Professor Maja-Lisa Løchen, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet.
When: 09.04.26 at 12.15–15.45
Where:
Nordlandssykehuset Bodø, auditoriet 9. etasje
Location / Campus: Digital, Bodø
Target group: Employees, Students, Guests, Invited, Unit
Contact: Andrea Jennerwein
E-mail: andrea.jennerwein@uit.no