Lars Småbrekke
Job description
I'm responsible for the courses Far-2101 and Far-3101, and contributes in teaching in several other courses on master & PhD level.
The research projects are mainly focused on consumption of antibiotics, antimicrobial resistance, and are based on data from population studies (e.g. The Tromsø studies & FitFutures), the Norwegian Prescription Database and clinical data from hospital practice.
Mohsen Gamal Saad Askar,
Lars Småbrekke,
Einar Jakobsen Holsbø,
Lars Ailo Aslaksen Bongo,
Kristian Svendsen
:
“Using network analysis modularity to group health code systems and decrease dimensionality in machine learning models”
Beate Hennie Garcia,
Katharina Kaino Omma,
Lars Småbrekke,
Jeanette Schultz Johansen,
frode Skjold,
Kjell Hermann Halvorsen
:
Investigating the impact of a pharmacist intervention on inappropriate prescribing practices at hospital admission and discharge in older patients: a secondary outcome analysis from a randomized controlled trial
Therapeutic Advances in Drug Safety 2024 DOI
Eirin Guldsten Robinson,
Hanna Gyllensten,
Jeanette Schultz Johansen,
Kjerstin Havnes,
Anne Gerd Granås,
Trine Strand Bergmo
et al.:
A Trial-Based Cost-Utility Analysis of a Medication Optimization Intervention Versus Standard Care in Older Adults
Ann Helen Jakobsen,
Lars Småbrekke,
Timothy F. Chen,
Kjell H. Halvorsen
:
Exploring stakeholders' perspectives on the quality of services provided through community pharmacies
Trine Strand Bergmo,
Vilde Sandsdalen,
Unn Sollid Manskow,
Lars Småbrekke,
Marit Waaseth
:
Internet Use for Obtaining Medicine Information: Cross-sectional Survey
Niclas Peter Raffelsberger,
Dorota Julia Buczek,
Kristian Svendsen,
Lars Småbrekke,
Anna Kaarina Pöntinen,
Iren Høyland Löhr
et al.:
Community carriage of ESBL-producing Escherichia coli and Klebsiella pneumoniae: a cross-sectional study of risk factors and comparative genomics of carriage and clinical isolates
Dina Benedicte Berg Stensen,
Lars Småbrekke,
Karina Olsen,
Guri Grimnes,
Christopher Sivert Nielsen,
Johanna U Ericson
et al.:
Circulating sex-steroids and Staphylococcus aureus nasal carriage in a general male population
Therese von Hanno,
Live Lund Hareide,
Lars Småbrekke,
Bente Morseth,
Monica Sneve,
Maja Gran Erke
et al.:
Macular Layer Thickness and Effect of BMI, Body Fat, and Traditional Cardiovascular Risk Factors: The Tromsø Study
Jeanette Schultz Johansen,
Kjell H. Halvorsen,
Kristian Svendsen,
Kjerstin Havnes,
Eirin Guldsten Robinson,
Hilde Ljones Wetting
et al.:
Interdisciplinary collaboration across secondary and primary care to improve medication safety in the elderly (The IMMENSE study) – a randomized controlled trial
Mari Johannessen Walquist,
Kristian Svendsen,
Beate Hennie Garcia,
Trine Strand Bergmo,
Anne Elise Eggen,
Kjell H. Halvorsen
et al.:
Self-reported medication information needs among medication users in a general population aged 40 years and above – the Tromsø study
Dina Benedicte Berg Stensen,
Rafael Nozal Cañadas,
Lars Småbrekke,
Karina Olsen,
Christopher Sivert Nielsen,
Kristian Svendsen
et al.:
Social network analysis of Staphylococcus aureus carriage in a general youth population
Sigbjørn Svalestuen,
Kristian Svendsen,
Anne Elise Eggen,
Lars Småbrekke
:
Association of area-level education with the regional growth trajectories of rates of antibacterial dispensing to patients under 3 years in Norway: a longitudinal retrospective study
Niclas Peter Raffelsberger,
Marit Andrea Klokkhammer Hetland,
Kristian Svendsen,
Lars Småbrekke,
Iren Høyland Löhr,
Lotte Andreassen
et al.:
Gastrointestinal carriage of Klebsiella pneumoniae in a general adult population: a cross-sectional study of risk factors and bacterial genomic diversity
Sanna Beckstrøm,
Kristian Svendsen,
Lars Småbrekke
:
Antibacterial use by birth year and birth season in children 0-2 years in Norway
Dina Benedicte Berg Stensen,
Lars Småbrekke,
Karina Olsen,
Guri Grimnes,
Christopher Sivert Nielsen,
Johanna U Ericson
et al.:
Circulating sex-steroids and Staphylococcus aureus nasal carriage in a general female population
Kirsten Midttun Gravningen,
Nigel Field,
Hege Salvesen Blix,
Anne Mette Asfeldt,
Lars Småbrekke
:
Non-prescription purchase of antibiotics during travel abroad among a general adult population in Norway: Findings from the seventh Tromsø Study
Guttorm Raknes,
Lars Småbrekke
:
No change in the consumption of thyroid hormones after starting low dose naltrexone (LDN): A quasi-experimental before-after study
June Utnes Høgli,
Beate Hennie Garcia,
Kristian Svendsen,
Vegard Skogen,
Lars Småbrekke
:
Empirical prescribing of penicillin G/V reduces risk of readmission of hospitalized patients with community-acquired pneumonia in Norway: a retrospective observational study
Guttorm Raknes,
Lars Småbrekke
:
Changes in the consumption of antiepileptics and psychotropic medicines after starting low dose naltrexone: A nation-wide register-based controlled before-after study
Ilya Nikolaevich Zykov,
Niels Frimodt-Møller,
Lars Småbrekke,
Arnfinn Sundsfjord,
Ørjan Samuelsen
:
Efficacy of mecillinam against clinical multidrug-resistant Escherichia coli in a murine urinary tract infection model
Dina Benedicte Berg Stensen,
Lars Småbrekke,
Karina Olsen,
Guri Grimnes,
Christopher Sivert Nielsen,
Gunnar Skov Simonsen
et al.:
Hormonal contraceptive use and Staphylococcus aureus nasal and throat carriage in a Norwegian youth population
Guttorm Raknes,
Lars Småbrekke
:
Low dose naltrexone: Effects on medication in rheumatoid and seropositive arthritis. A nationwide register-based controlled quasi-experimental before-after study
O D'Annibali,
G Bonaldo,
Monia Donati,
Lars Småbrekke,
Domenico Motola,
A Vaccheri
:
Antibacterial prescription in Italian preschool children: analysis of 7 years of data from the Emilia-Romagna region reimbursement database
Journal of Antimicrobial Chemotherapy 01. August 2019 DOI
Cecilia S. Sambakunsi,
Lars Småbrekke,
Christine A. Varga,
Vernon Solomon,
John S. Mponda
:
Knowledge, attitudes and practices related to self-medication with antimicrobials in Lilongwe, Malawi
Guttorm Raknes,
Pia Simonsen,
Lars Småbrekke
:
The effect of low-dose naltrexone on medication in inflammatory bowel disease: A quasi experimental before-and-after prescription database study
Ilya Nikolaevich Zykov,
Ørjan Samuelsen,
Lotte Jakobsen,
Lars Småbrekke,
Dan I. Andersson,
Arnfinn Sundsfjord
et al.:
Pharmacokinetics and pharmacodynamics of fosfomycin and its activity against extended-spectrum-lactamase-, plasmid-mediated AmpC-, and carbapenemase-producing escherichia coli in a murine urinary tract infection model
Pål Haugen,
Gunnar Skov Simonsen,
Raul Primicerio,
Anne-Sofie Furberg,
Lars Småbrekke
:
Antibiotics to outpatients in Norway—Assessing effect of latitude and municipality population size using quantile regression in a cross-sectional study.
Bjørg Haldorsen,
Christian G Giske,
Dennis S Hansen,
Kristjan Orri Helgason,
Gunnar Kahlmeter,
Iren Høyland Löhr
et al.:
Performance of the EUCAST disc diffusion method and two MIC methods in detection of Enterobacteriaceae with reduced susceptibility to meropenem: the NordicAST CPE study.
Guttorm Raknes,
Lars Småbrekke
:
Low dose naltrexone in multiple sclerosis: Effects on medication use. A quasi-experimental study
Guttorm Raknes,
Lars Småbrekke
:
Low-dose naltrexone and opioid consumption: a drug utilization cohort study based on data from the Norwegian prescription database
Pharmacoepidemiology and Drug Safety 2017 DOI
Guttorm Raknes,
Lars Småbrekke
:
A sudden and unprecedented increase in low dose naltrexone (LDN) prescribing in Norway. Patient and prescriber characteristics, and dispense patterns. A drug utilization cohort study
June Utnes Høgli,
Beate Hennie Garcia,
frode Skjold,
Vegard Skogen,
Lars Småbrekke
:
An audit and feedback intervention study increased adherence to antibiotic prescribing guidelines at a Norwegian hospital
Beate Hennie Garcia,
Trude Giverhaug,
June U. Høgli,
Frode Skjold,
Lars Småbrekke
:
A pharmacist-led follow-up program for patients with established coronary heart disease in North Norway – A randomized controlled trial
[Programa farmacéutico de seguimiento para pacientes con enfermedad coronaria establecida en El Norte de Noruega – Ensayo controlado aleatorizado]
Ilya Nikolaevich Zykov,
Arnfinn Sundsfjord,
Lars Småbrekke,
Ørjan Samuelsen
:
The antimicrobial activity of mecillinam, nitrofurantoin, temocillin and fosfomycin and comparative analysis of resistance patterns in a nationwide collection of ESBL-producing Escherichia coli in Norway 2010–2011
Infectious Diseases 2015 DOI
Mauro Melis,
Chiara Biagi,
Lars Småbrekke,
Francesco Nonino,
Elena Buccellato,
Monia Donati
et al.:
Drug-Induced Progressive Multifocal Leukoencephalopathy: A Comprehensive Analysis of the WHO Adverse Drug Reaction Database
CNS Drugs 2015 DOI
June Utnes Høgli,
Lars Småbrekke,
Beate Garcia
:
MAT-CAP: A novel medication assessment tool to explore adherence to clinical practice guidelines in community-acquired pneumonia
Pharmacoepidemiology and Drug Safety 2014 DOI
Mohsen Gamal Saad Askar,
Masoud Tafavvoghi,
Lars Småbrekke,
Lars Ailo Bongo,
Kristian Svendsen
:
Using machine learning methods to predict all-cause somatic hospitalizations in adults: A systematic review
PLOS ONE 2024 DOI
Dina Benedicte Berg Stensen,
Lars Småbrekke,
Karina Olsen,
Christopher Sivert Nielsen,
Johanna Ericson Sollid,
Gunnar Skov Simonsen
et al.:
Circulating sex-steroids and Staphylococcus aureus nasal carriage in a general population in Norway
2021
Dina Benedicte Berg Stensen,
Rafael A. Nozal Cañadas,
Lars Småbrekke,
Karina Olsen,
Christopher Sivert Nielsen,
Kristian Svendsen
et al.:
Social network analysis of Staphylococcus aureus carriage in a general youth population
2021
Dina Benedicte Berg Stensen,
Lars Småbrekke,
Karina Olsen,
Guri Grimnes,
Christopher Sivert Nielsen,
Johanna Ericson Sollid
et al.:
Circulating sex-steroids and Staphylococcus aureus nasal carriage in a general female population
2021
Angela Lupattelli,
Øystein Karlstad,
Anders Engeland,
Lars Småbrekke,
Kristine Olsen,
Aina Øvrebust
et al.:
The Norwegian Society for Pharmacoepidemiology
Ann Helen Jakobsen,
Kjell H. Halvorsen,
Lars Småbrekke
:
Forslag til kvalitetsindikatorer for primærapotek
2019
Lyn Middleton,
F Lampiao,
Tomas F. Zimba,
SM Muzime,
Gunnar Skov Simonsen,
Lars Småbrekke
et al.:
Sharing Knowledge Transforming Societies. The Norhed Programme 2013-2020
African Minds 2019
Guttorm Raknes,
Pia Simonsen,
Lars Småbrekke
:
Erratum: The Effect of Low-Dose Naltrexone on Medication in Inflammatory Bowel Disease: A Quasi Experimental Before-and-After Prescription Database Study (Journal of Crohn's and Colitis DOI: 10.1093/ecco-jcc/jjy008)
Journal of Crohn's and Colitis 2019 DOI
Kristian Svendsen,
Øystein Karlstad,
Lars Småbrekke
:
To the editor
JAMA Internal Medicine 2018 DOI
Kristian Svendsen,
Øystein Karlstad,
Lars Småbrekke
:
Lower cancer incidence-warfarin effect or immortal time bias?
JAMA Internal Medicine 2018 DOI
Martin Sørensen,
Annette Kuehn,
E.N. Clare Mills,
Carol Ann Costello,
Markus Ollert,
Lars Småbrekke
et al.:
Cross-reactivity in fish allergy: A double-blind, placebo-controlled food-challenge trial
Journal of Allergy and Clinical Immunology 2017 DOI
Dina Stensen,
Lars Småbrekke,
Karina Olsen,
Guri Grimnes,
Christopher Sivert Nielsen,
Gunnar Skov Simonsen
et al.:
Hormonal contraceptive use and Staphylococcus aureus nasal and throat carriage in a Norwegian youth population. The Tromsø Study Fit Futures 2.
2017
Kristian Svendsen,
Håvard Wahl Kongsgård,
Pål Haugen,
Lars Småbrekke
:
Does travel time to pharmacies and general physicians influence the use of antibiotics in Norway?
2016
Tone Ruud Engen,
Beate Hennie Garcia,
Kjell H. Halvorsen,
Marit Waaseth,
Lars Småbrekke,
Hilde Ljones Wetting
:
Er det trygt å velge billigere resept-medisiner?
22. January 2015 DATA
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Research interests
Clinical pharmacy and drug consumption on population level, mainly focusing on antibiotics.
Member of research group
CV
See above.