Bilde av Gabrielsen, Mari
Bilde av Gabrielsen, Mari
Associate Professor Eksperimentell og klinisk farmakologi mari.gabrielsen@uit.no +4777644877 Tromsø You can find me here

Mari Gabrielsen



  • Linn Samira Mari Evenseth, Clizia Russotto, Imin Wushur, Dawid Warszycki, Angel Moldes-Anaya, Andrzej J. Bojarski et al.:
    Identification of Orthosteric GABAB Receptor Ligands by Virtual Screening and In Vitro Validation
    ACS Omega 2025 DOI / ARKIV
  • Ingebrigt Sylte, Mari Gabrielsen, kurt Kristiansen :
    Homology Modeling of Transporter Proteins
    Methods in molecular biology 2023 DOI / ARKIV
  • Linn Evenseth, Riccardo Ocello, Mari Gabrielsen, Matteo Masetti, Maurizio Recanatini, Ingebrigt Sylte et al.:
    Exploring Conformational Dynamics of the Extracellular Venus flytrap Domain of the GABA B Receptor: A Path-Metadynamics Study
    Journal of Chemical Information and Modeling 2020 DOI / ARKIV
  • Linn Evenseth, Mari Gabrielsen, Ingebrigt Sylte :
    The GABAB Receptor—Structure, Ligand Binding and Drug Development
    Molecules 2020 DOI / ARKIV
  • Linn Evenseth, Dawid Warszycki, Andrzej J Bojarski, Mari Gabrielsen, Ingebrigt Sylte :
    In Silico Methods for the Discovery of Orthosteric GABAB Receptor Compounds
    Molecules 2019 DOI / ARKIV
  • Ove Alexander Høgmoen Åstrand, Elvar Örn Viktorsson, Aleksander Lim Kristensen, Dag Ekeberg, Hanne Røberg-Larsen, Steven Ray Haakon Wilson et al.:
    Synthesis, in vitro and in vivo biological evaluation of new oxysterols as modulators of the liver X receptors
    Journal of Steroid Biochemistry and Molecular Biology 2017 DOI / ARKIV
  • Elvar Örn Viktorsson, Mari Gabrielsen, Nugalya Kumarachandran, Ingebrigt Sylte, Pål Rongved, Ove Alexander Høgmoen Åstrand et al.:
    Regulation of liver X receptor target genes by 22-functionalized oxysterols. Synthesis, in silico and in vitro evaluations
    Steroids 2017 DOI / ARKIV
  • Thibaud Freyd, Dawid Warszycki, Stefan Mordalski, Andrzej J Bojarski, Ingebrigt Sylte, Mari Gabrielsen :
    Ligand-guided homology modelling of the GABA<sub>B2</sub> subunit of the GABA<sub>B</sub> receptor
    PLOS ONE 2017 DOI / ARKIV / ARKIV
  • Irina Kufareva, Vsevolod Katritch, Thibaud Freyd, Mari Gabrielsen, kurt Kristiansen, Ingebrigt Sylte et al.:
    Advances in GPCR modeling evaluated by the GPCR Dock 2013 assessment: Meeting new challenges
    Structure 2014 DOI / ARKIV
  • Mari Gabrielsen, Rafal Kurczab, Agata Siwek, Malgorzata Wolak, Aina Westrheim Ravna, kurt Kristiansen et al.:
    Identification of novel serotonin transporter compounds by virtual Screening
    Journal of Chemical Information and Modeling 2014 DOI / ARKIV
  • Mari Gabrielsen, Karol Wolosewicz, Anna Zawadzka, Jerzy Kossakowski, Gabriel Nowak, Malgorzata Wolak et al.:
    Synthesis, Antidepressant Evaluation and Docking Studies of Long-Chain Alkylnitroquipazines as Serotonin Transporter Inhibitors
    Chemical Biology and Drug Design (CB&DD) 2013 DOI / ARKIV
  • Yan Baglo, Mari Gabrielsen, Ingebrigt Sylte, Odrun Arna Gederaas :
    Homology Modeling of Human -Butyric Acid Transporters and the Binding of Pro-drugs 5-Aminolevulinic Acid and Methyl Aminolevulinic Acid used in Photodynamic Therapy
    PLOS ONE 2013 DOI / ARKIV
  • Malgorzata Jaronczyk, Karol Wolosewicz, Mari Gabrielsen, Gabriel Nowak, Irina Kufareva, Aleksander P Mazurek et al.:
    Synthesis, in vitro binding studies and docking of long-chain arylpiperazine nitroquipazine analogues, as potential serotonin transporter inhibitors
    European Journal of Medicinal Chemistry 2012 DOI / ARKIV
  • Mari Gabrielsen, aina westrheim Ravna, kurt Kristiansen, Ingebrigt Sylte :
    Substrate binding and translocation of the serotonin transporter studied by docking and molecular dynamics simulations
    Journal of Molecular Modeling 2012 DOI / ARKIV
  • Mari Gabrielsen, Rafal Kurczab, aina westrheim Ravna, Irina Kufareva, Ruben Abagyan, Zdzislaw Chilmonczyk et al.:
    Molecular mechanism of serotonin transporter inhibition elucidated by a new flexible docking protocol
    European Journal of Medicinal Chemistry 2012 DOI / ARKIV
  • Mari Gabrielsen, Ingebrigt Sylte, Svein G. Dahl, aina westrheim Ravna :
    A short update on the structure of drug binding sites on neurotransmitter transporters
    BMC Research Notes 2011 DOI / ARKIV
  • Yan Baglo, Mari Gabrielsen, Ingebrigt Sylte, Odrun Arna Gederaas :
    Homology Modeling of Human -Butyric Acid Transporters and the Binding of Pro-drugs 5-Aminolevulinic Acid and Methyl Aminolevulinic Acid used in Photodynamic Therapy
    2013 ARKIV
  • Mari Gabrielsen :
    The search for new SERT inhibitors, possible antidepressant drugs
    2011 ARKIV
  • Mari Gabrielsen :
    Docking of substrates and inhibitors into the substrate binding site of two serotonin transporter models
    2011 ARKIV
  • Mari Gabrielsen, Ingebrigt Sylte :
    Structure, function and inhibition of the serotonin transporter studied by molecular docking, -dynamics and virtual screening
    UiT Norges arktiske universitet 16. September 2011 ARKIV

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    Research interests

    Pharmacology and toxicology

    G-protein coupled receptors (GPCRs) - Neuropharmacology - Basic pharmacology

    In silico methods (homology modelling, docking and scoring, molecular dynamics simulations (MD simulations), virtual screening)

    Teaching

    Teach pharmacology (toxicology) at several of the study programmes at the Faculty of Health Sciences, UiT the Arctic University of Norway

    Unit leader of Pharmacology

    Course management: ODO-2008 Biomedisin 1 og Viten (Odontology 2nd year, 30 ECTS) and MBI-3015 Human Pharmacology and Toxicology (Biomedicine master level course, 10 ECTS)





    MH øst L9.122


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