Bilde av Johannessen, Mona
Bilde av Johannessen, Mona
Professor Department of Medical Biology mona.johannessen@uit.no +4777646225 You can find me here

Mona Johannessen


Job description

Mona Johannessen (PhD) is the leader of Research Group for Host-Microbe interaction (HMI), at Department of Medical Biology (IMB). 

She is professor in molecular/cell biology and is especially interested in molecular aspects of host-microbe interplay, including bacterial adaptation to host which includes, but are not limited too, the expression and functions of factors involved in adhesion, invasion and immune evasion. 

Johannessen is also highly involved in teaching at bachelor-, master- and PhD level courses, and in mentoring of post docs as well as supervision of PhD-, master- and bachelor students. 


  • Stephen Dela Ahator, Kristin Hegstad, Christian Stephan Lentz, Mona Susan Johannessen :
    Deciphering Staphylococcus aureus–host dynamics using dual activity-based protein profiling of ATP-interacting proteins
    mSystems 2024 ARKIV / DOI
  • Silje Mork, Mona Susan Johannessen, Natasa Skalko Basnet, May Wenche Bakke Jøraholmen :
    Chitosan and liposomal delivery systems for epicatechin or propyl gallate targeting localized treatment of vulvovaginal candidiasis
    International Journal of Pharmaceutics 2024 ARKIV / DOI
  • Srijana Bastakoti, Maiju Pesonen, Clément Ajayi, Kjersti Julin, Jukka Corander, Mona Susan Johannessen et al.:
    Co-culturing with Streptococcus anginosus alters Staphylococcus aureus transcriptome when exposed to tonsillar cells
    Frontiers in Cellular and Infection Microbiology 2024 ARKIV / DOI
  • Stephen Dela Ahator, Karoline Wenzl, Kristin Hegstad, Christian Stephan Lentz, Mona Susan Johannessen :
    Comprehensive virulence profiling and evolutionary analysis of specificity determinants in Staphylococcus aureus two-component systems
    mSystems 2024 ARKIV / DOI
  • Theresa Maria Wagner, Anna Kaarina Pöntinen, Carolin Kornelia Fenzel, Daniel Engi, Jessin Janice, Ana C. Almeida-Santos et al.:
    Interactions between commensal Enterococcus faecium and Enterococcus lactis and clinical isolates of Enterococcus faecium
    FEMS microbes 2024 ARKIV / DOI
  • Laura Victoria Schulte-Werning, Bhupender Singh, Mona Susan Johannessen, Rolf Einar Engstad, Ann-Mari Holsæter :
    Antimicrobial liposomes-in-nanofiber wound dressings prepared by a green and sustainable wire-electrospinning set-up
    International Journal of Pharmaceutics 2024 ARKIV / DOI
  • Roni Miah, Mona Susan Johannessen, Morten Kjos, Christian Stephan Lentz :
    Development of an inducer-free, virulence gene promoter-controlled, and fluorescent reporter-labeled CRISPR interference system in Staphylococcus aureus
    Microbiology spectrum 2024 ARKIV / DOI
  • Jonathan Hira, Bhupender Singh, Tirthankar Halder, Anel Mahmutovic, Clément Ajayi, Arif Ahmed Sekh et al.:
    Single-cell phenotypic profiling and backtracing exposes and predicts clinically relevant subpopulations in isogenic Staphylococcus aureus communities
    Communications Biology 2024 ARKIV / DOI
  • Srijana Bastakoti, Clement Ajayi, Kjersti Julin, Mona Johannessen, Anne Merethe Hanssen :
    Exploring differentially expressed genes of Staphylococcus aureus exposed to human tonsillar cells using RNA sequencing
    BMC Microbiology 2023 ARKIV / DOI
  • Alexandra Sofia Antunes de Sousa, Vegard Borøy, Agnethe Hansen Bæverud, Kjersti Julin, Annette Bayer, Morten B. Strøm et al.:
    Polymyxin B stabilized DNA micelles for sustained antibacterial and antibiofilm activity against P. aeruginosa
    Journal of materials chemistry. B 2023 ARKIV / DOI
  • Theresa Maria Wagner, Felipe Romero-Saavedra, Diana Laverde, Mona Susan Johannessen, Johannes Hübner, Kristin Hegstad :
    Enterococcal Membrane Vesicles as Vaccine Candidates
    International Journal of Molecular Sciences 2023 ARKIV / DOI
  • Lisa Myrseth Hemmingsen, Pimmat Panchai, Kjersti Julin, Purusotam Basnet, Mona Nystad, Mona Johannessen et al.:
    Chitosan-based delivery system enhances antimicrobial activity of chlorhexidine
    Frontiers in Microbiology 2022 ARKIV / DOI
  • Lisa Myrseth Hemmingsen, Kjersti Julin, Luquman Mian Ahsan, Purusotam Basnet, Mona Johannessen, Natasa Skalko-Basnet :
    Chitosomes-in-chitosan hydrogel for acute skin injuries: Prevention and infection control
    Marine Drugs 2021 ARKIV / DOI
  • Bishnu Joshi, Bhupender Singh, Aftab Nadeem, Fatemeh Askarian, Sun Nyunt Wai, Mona Johannessen et al.:
    Transcriptome profiling of staphylococcus aureus associated extracellular vesicles reveals presence of small RNA-cargo
    Frontiers in Molecular Biosciences 13. January 2021 ARKIV / DOI
  • Sybil Akua Okyerewa Obuobi, Anna Ngoc Phung, Kjersti Julin, Mona Johannessen, Natasa Skalko-Basnet :
    Biofilm Responsive Zwitterionic Antimicrobial Nanoparticles to Treat Cutaneous Infection
    Biomacromolecules 2021 ARKIV / DOI
  • Monika Kumaraswamy, Kamilla Wiull, Bishnu Joshi, George Sakoulas, Armin Kousha, Gustav Vaaje-Kolstad et al.:
    Bacterial membrane-derived vesicles attenuate vancomycin activity against methicillin-resistant staphylococcus aureus
    Microorganisms 2021 ARKIV / DOI
  • Laura Schulte Werning, Anjanah Murugaiah, Bhupender Singh, Mona Johannessen, Rolf Einar Engstad, Natasa Skalko-Basnet et al.:
    Multifunctional Nanofibrous Dressing with Antimicrobial and Anti-Inflammatory Properties Prepared by Needle-Free Electrospinning
    Pharmaceutics 2021 ARKIV / DOI
  • May Wenche Jøraholmen, Mona Johannessen, Kirsten Midttun Gravningen, Mirja Puolakkainen, Ganesh Acharya, Purusotam Basnet et al.:
    Liposomes-in-hydrogel delivery system enhances the potential of resveratrol in combating vaginal chlamydia infection
    Pharmaceutics 11. December 2020 ARKIV / DOI
  • May Wenche Jøraholmen, Abhilasha Bhargava, Kjersti Julin, Mona Johannessen, Natasa Skalko-Basnet :
    The Antimicrobial Properties of Chitosan Can be  Tailored by Formulation
    Marine Drugs 2020 ARKIV / DOI
  • Sybil Akua Okyerewa Obuobi, Kjersti Julin, Elizabeth G. Aarag Fredheim, Mona Johannessen, Natasa Skalko-Basnet :
    Liposomal delivery of antibiotic loaded nucleic acid nanogels with enhanced drug loading and synergistic anti-inflammatory activity against S. aureus intracellular infections
    Journal of Controlled Release 2020 ARKIV / DOI
  • Adriana Maria Sanabria-Moreno, Erik Hjerde, Mona Johannessen, Johanna U Ericson Sollid, Gunnar Skov Simonsen, Anne Merethe Hanssen :
    Shotgun-Metagenomics on Positive Blood Culture Bottles Inoculated With Prosthetic Joint Tissue: A Proof of Concept Study
    Frontiers in Microbiology 2020 ARKIV / DOI
  • Dmytro Kravtsov, Mona Susan Johannessen, Mauri A Kostiainen, Natasa Skalko Basnet, Sybil Akua Okyerewa Obuobi :
    Rational design of aptamer-based nanostructures for bacterial biofilm applications
    2024
  • Alexandra Sofia Antunes De Sousa, Mona Susan Johannessen, Annette Bayer, Morten Bøhmer Strøm, Natasa Skalko Basnet, Sybil Akua Okyerewa Obuobi :
    Study of the penetration ability of DNA nanoparticles in biofilms
    2024
  • Theresa Wagner, Felipe Romero-Saavedra, Diana Laverde, Mona Johannessen, Johannes Hübner, Kristin Hegstad :
    Enterococcal Membrane Vesicles as Vaccine Candidates
    2023
  • Alexandra Sofia Antunes de Sousa, Kjersti Julin, Annette Bayer, Morten Bøhmer Strøm, Mona Johannessen, Natasa Skalko-Basnet et al.:
    Drug-loaded DNA nanoparticles against bioflms
    2023
  • Carolin Kornelia Fenzel, Anna K. Pöntinen, Mona Johannessen, Kristin Hegstad, Theresa Wagner :
    Characterization of competition between commensal and clinical strains of Enterococcus faecium​
    2023
  • Theresa Wagner, Anna Kaarina Pöntinen, Carolin Kornelia Fenzel, Daniel Engi, Jessin Janice, Ana Almeida-Santos et al.:
    Competition between commensal Enterococcus faecium and Enterococcus lactis and clinical isolates of E. faecium
    2023
  • Ingeborg Mathiesen, Anna Kaarina Pöntinen, Mona Johannessen, Kristin Hegstad, Theresa Wagner :
    Characterization of Putative Virulence Factors in Enterococcus faecium
    2023
  • Ingeborg Mathiesen, Theodor Anton Ross, Anna Kaarina Pöntinen, Einar Holsbø, Michael Kampffmeyer, Mona Johannessen et al.:
    Characterization of Putative Virulence Factors in Enterococcus faecium
    2023
  • Jonathan Hira, Bhupender Singh, Clément Ajayi, Mona Susan Johannessen, Christian Stephan Lentz :
    Sorting out their differences – High-throughput phenotypic profiling of single cells and subpopulations within isogenic bacterial pathogen cell populations
    2023
  • Jonathan Hira, Bhupender Singh, Theresa Maria Wagner, Kristin Hegstad, Mona Susan Johannessen, Christian Stephan Lentz :
    A high-throughput platform for phenotypic profiling of bacteria coupled to single cell-derived growth analysis
    2023
  • Mona Susan Johannessen :
    Hva menes med antibiotika-resistense, og hva kan vi gjøre med det?
    Foredrag for ungdomsskole-klasser, helsedagene-2023. 2023
  • Srijana Bastakoti, maiju Pesonen, Clément Ajayi, Kjersti Julin, Mona Susan Johannessen, Jukka Corander et al.:
    Co-culturing with Streptococcus anginosus alters Staphylococcus aureus transcriptome when exposed to tonsillar cells
    2023
  • Anne-Merethe Christiansen Hanssen, Clément Ajayi, Mona Susan Johannessen, Kjersti Julin, Maiju Pesonen, Jukka Corander et al.:
    Co-culturing with Streptococcus anginosus alters Staphylococcus aureus transcriptome when exposed to tonsillar cells
    2023
  • Srijana Bastakoti, Maiju Pesonen, Clément Ajayi, Kjersti Julin, Jukka Corander, Mona Susan Johannessen et al.:
    Co-culturing with Streptococcus anginosus alters Staphylococcus aureus transcriptome when exposed to tonsillar cells
    2023
  • Srijana Bastakoti, Maiju Pesonen, Clément Ajayi, Kjersti Julin, Jukka Corander, Mona Susan Johannessen et al.:
    Co-culturing with Streptococcus anginosus alters Staphylococcus aureus transcriptome when exposed to tonsillar cells
    2023
  • Ingeborg Mathiesen, Mona Johannessen, Kristin Hegstad, Theresa Wagner :
    Characterisation of putative virulence factors in Enterococcus faecium
    2022
  • Mona Johannessen :
    Antibiotika-resistens- hva er det og hva gjør vi med det?
    Foredrag for skoleelever i forbindelse med Forskningsdagene 2022 2022
  • Ingeborg Mathiesen, Mona Johannessen, Kristin Hegstad, Theresa Wagner :
    Characterisation of putative virulence factors in Enterococcus faecium
    2022
  • Kjersti Julin, Annette Bayer, Morten Bøhmer Strøm, Mona Johannessen, Natasa Skalko-Basnet, Sybil Akua Okyerewa Obuobi :
    DNA Nanocarriers for improved biofilm penetration
    2022
  • Srijana Bastakoti, Clément Ajayi, Kjersti Julin, Mona Susan Johannessen, Anne-Merethe Christiansen Hanssen :
    Exploring differentially expressed genes of Staphylococcus aureus exposed to human tonsillar cells using RNA sequencing
    2022
  • Sybil Akua Okyerewa Obuobi, Anna Ngoc Phung, Kjersti Julin, Mona Johannessen, Natasa Skalko-Basnet :
    Multi-responsive and Zwitterionic Nanohybrids for the Treatment of Biofilm Wound Infections
    2021
  • Sybil Akua Okyerewa Obuobi, Anna Ngoc Phung, Kjersti Julin, Mona Johannessen, Natasa Skalko-Basnet :
    Zwitterionic hybrid nanoparticles for the treatment of biofilm wound infections
    2021
  • Sybil Akua Okyerewa Obuobi, Anna Ngoc Phung, Kjersti Julin, Mona Johannessen, Natasa Skalko-Basnet :
    Zwitterionic Nanohybrids for the Treatment of Wound Biofilms
    2021
  • Sybil Akua Okyerewa Obuobi, Anna Ngoc Phung, Kjersti Julin, Mona Johannessen, Natasa Skalko-Basnet :
    Multi-responsive and Zwitterionic Nanohybrids for the Treatment of Biofilm Wound Infections
    2021
  • Sybil Akua Okyerewa Obuobi, Anna Ngoc Phung, Kjersti Julin, Mona Johannessen, Natasa Skalko-Basnet :
    ZWITTERIONIC NUCLEIC ACID HYBRIDS FOR THE TREATMENT OF BIOFILM INFECTIONS
    2021
  • Sybil Akua Okyerewa Obuobi, Kjersti Julin, Elizabeth G. Aarag Fredheim, Pål Jarle Johnsen, Mona Johannessen, Natasa Skalko-Basnet :
    Liposomal delivery of antibiotic loaded DNA nanogels against intracellular infections
    2020
  • Theresa Wagner, Mona Johannessen, Kristin Hegstad :
    Towards a vaccine based on enterococcal membrane vesicles
    2020
  • Sybil Akua Okyerewa Obuobi, Kjersti Julin, Elizabeth G. Aarag Fredheim, Mona Johannessen, Natasa Skalko-Basnet :
    Liposomal delivery of Nucleic Acid Nanogels to Enhance Entrapment Efficiency and Sustain Release of Antibiotics against Staphylococcal intracellular infections
    2020
  • Theresa Wagner, Clement Ajayi, Mona Johannessen, Kristin Hegstad, Gro Grimnes, Ingrid Hemmingsen :
    Brukermøte 2020
    2020

  • The 50 latest publications is shown on this page. See all publications in Cristin here →


    Research interests

    Johannessen main research interest is to identify, explore and get in-depth understanding of species such as Staphylococcus aureus, Enterococcus faecium and/or Klebsiella pneumoniae with respect to...

    1) host-microbe interaction, especially bacterial factors involved in colonisation and infection.  

    2) bacterial adaptation to various host niches and phenotypic heterogeneity 

    3) bacterial membrane vesicles

     

    Teaching

    Johannessen is in charge of MBI-1002 Molecular and cell biology (15 ECTS), a course taken by seven different study programs.

    Additionally, she currently teach in MBI-3012 Advanced methods in experimental biomedicine (30ECTS), MBI-3014 Infection, inflammation and immunity (10 ECTS), MBI-8005 advanced and interactive antimicrobial resistance course (3 ECTS) at UiT and at the PhD course "Pathogen immune vasion strategies" at NTNU. 

    She has previously been in charge of Study program for Biomedicine, been course leader for Msc-courses named "Virology", "Mammalian cell culture", "Infection, inflammation and immunity", and taught in Bsc-courses named "Biochemistry", "Cell biology", "Genetics" and Msc-courses named "Eukaryotic transcription factors", "Normal flora/Infection/Immunity", "Health-security-environment", "Molecular genetical methods", and PhD courses "Frontiers in molecular and structureal biology".


    Member of research group