Bjarne Østerud
Job description
Professor in biochemistry, Department of Medical Biology, University of Tromsø
Eduarda Mazagao Guerreiro,
Sergei G. Kruglik,
Samantha Swamy,
Nadezhda Latysheva,
Bjarne Østerud,
Jean-Michel Guigner
et al.:
Extracellular vesicles from activated platelets possess a phospholipid-rich biomolecular profile and enhance prothrombinase activity
Amandine Bonifay,
Nigel Mackman,
Yohei Hisada,
Ana Teresa Azevedo Sachetto,
Chi Hau,
Elaine Gray
et al.:
Comparison of assays measuring extracellular vesicle tissue factor in plasma samples: communication from the ISTH SSC Subcommittee on Vascular Biology
Journal of Thrombosis and Haemostasis 2024 DOI
Torstein Lindahl Schanche,
Ole Magnus Filseth,
Bjarne Østerud,
Timofey Kondratyev,
Gary C. Sieck,
Torkjel Tveita
:
Enhanced Blood Clotting After Rewarming From Experimental Hypothermia in an Intact Porcine Model
Gábor Szabó,
Ildikó Beke Debreceni,
Tünde Tarr,
P. Soltesz,
Bjarne Østerud,
János Kappelmayer
:
Anti-β2-glycoprotein I autoantibodies influence thrombin generation parameters via various mechanisms
Bjarne Østerud,
Nadezhda Latysheva,
Christian Schoergenhofer,
Bernd Jilma,
John-Bjarne Hansen,
Omri Snir
:
A rapid, sensitive, and specific assay to measure TF activity based on chromogenic determination of thrombin generation
Bjarne Østerud,
Beth A Bouchard
:
Detection of tissue factor in platelets: why is it so troublesome?
Emil Kostovski,
E Frigato,
Mladen Savikj,
Anders Erik A Dahm,
Per Morten Sandset,
Marie-Christine Mowinckel
et al.:
Normalization of disrupted clock gene expression in males with tetraplegia: a crossover randomized placebo-controlled trial of melatonin supplementation
Mari Walquist,
Svein Kristian Stormo,
Bjarne Østerud,
Edel Oddny Elvevoll,
Karl-Erik Eilertsen
:
Cold-pressed minke whale oil reduces circulating LDL/VLDL-cholesterol, lipid oxidation and atherogenesis in apolipoprotein E-deficient mice fed a Western-type diet for 13 weeks
Mari Walquist,
Svein Kristian Stormo,
Ida-Johanne Jensen,
Bjarne Østerud,
Karl-Erik Eilertsen
:
Antioxidant and Anti-Inflammatory Activities in Extracts from Minke Whale (Balaenoptera acutorostrata) Blubber
Erik Boye,
Tore Skotland,
Bjarne Østerud,
Jon Nissen-Meyer
:
Doping and drug testing
EMBO Reports 2017 DOI
Renata Hudak,
Ildiko Beke Debreceni,
Ivett Deak,
Gabriella Gal Szabo,
Zsuzsanna Hevessy,
Peter Antal-Szalmas
et al.:
Laboratory characterization of leukemic cell procoagulants
Clinical Chemistry and Laboratory Medicine 2017 DOI
Jon Nissen-Meyer,
Erik Boye,
Bjarne Østerud,
Tore Skotland
:
Another troubling doping case is questioning WADA’s credibility again: Borderline Analysis
Lab Times 2016
Jon Nissen-Meyer,
Erik Boye,
Bjarne Østerud,
Tore Skotland
:
EPO Testing in Doping Control Laboratories is Absolutely No Joke
Lab Times 2016
Anne Landsem,
Hilde Fure,
Dorte Christiansen,
Erik Waage Nielsen,
Bjarne Østerud,
Tom Eirik Mollnes
et al.:
The key roles of complement and tissue factor in Escherichia coli-induced coagulation in human whole blood
Clinical and Experimental Immunology 2015 DOI
Karianne Fredenfeldt Lind,
Bjarne Østerud,
Espen Hansen,
Trond Ø. Jørgensen,
Jeanette hammer Andersen
:
The immunomodulatory effects of barettin and involvement of the kinases CAMK1α and RIPK2
Immunopharmacology and immunotoxicology 2015 DOI
Bjarne Østerud,
D. Unruh,
Jan Ole Olsen,
D. Kirchhofer,
A P Owens,
V.Y. Bogdanov
:
Procoagulant and proinflammatory effects of red blood cells on lipopolysaccharide-stimulated monocytes
Journal of Thrombosis and Haemostasis 2015 DOI
Jon Nissen-Meyer,
Erik Boye,
Bjarne Østerud,
Tore Skotland
:
Problems at a WADA-accredited anti-doping lab: Puzzling Discrepancy
Lab Times 2015
Emil Kostovski,
Anders Erik A Dahm,
Marie-Christine Mowinckel,
Annicke Stranda,
Grethe Skretting,
Bjarne Østerud
et al.:
Circadian rhythms of hemostatic factors in tetraplegia: a double-blind, randomized, placebo-controlled cross-over study of melatonin
Per Ole Iversen,
Anders Erik A Dahm,
Grethe Skretting,
Marie-Christine Mowinckel,
Annicke Stranda Haslestad,
Bjarne Østerud
et al.:
Reduced peak, but no diurnal variation, in thrombin generation upon melatonin supplementation in tetraplegia. A randomised, placebo-controlled study.
Thrombosis and Haemostasis 2015 DOI
Sandra T.A. Van Bijnen,
Bjarne Østerud,
Wideke Barteling,
Kitty Verbeek-Knobbe,
M. Willemsen,
Waander L. van Heerde
et al.:
Alterations in markers of coagulation and fibrinolysis in patients with Paroxysmal Nocturnal Hemoglobinuria before and during treatment with eculizumab
Thrombosis Research 2015 DOI
Bjarne Østerud,
Jan Ole Olsen
:
Pro- and anti-inflammatory effects of histamine on tissue factor and TNFα expression in monocytes of human blood
Thrombosis Research 2014 DOI
DI Feinstein,
Bjarne Østerud,
LVM Rao
:
The partial thromboplastin time: Reply
Journal of Thrombosis and Haemostasis 2014 DOI
Jon Nissen-Meyer,
Erik Boye,
Bjarne Østerud,
Tore Skotland
:
WADA-accredited doping analyses cannot always be trusted
Lab Times 2013
Bjarne Østerud,
Jan Ole Olsen
:
Human platelets do not express tissue factor
Thrombosis Research 2013 DOI
Karianne Fredenfeldt Lind,
Espen Hansen,
Bjarne Østerud,
Karl-Erik Eilertsen,
Annette Bayer,
Stig Olov Magnus Engqvist
et al.:
Antioxidant and Anti-Inflammatory Activities of Barettin
Anne Landsem,
Erik Waage Nielsen,
Hilde Fure,
Dorte Christiansen,
Judith K Ludviksen,
J.D. Lambris
et al.:
C1-inhibitor efficiently inhibits Escherichia coli-induced tissue factor mRNA up-regulation, monocyte tissue factor expression and coagulation activation in human whole blood
Clinical and Experimental Immunology 2013 DOI
Ole Lars Brekke,
Knut-Christian Waage,
Dorte Christiansen,
Hilde Fure,
H Qu,
John D. Lambris
et al.:
The Effects of Selective Complement and CD14 Inhibition on the E. coli -Induced Tissue Factor mRNA Upregulation, Monocyte Tissue Factor Expression, and Tissue Factor Functional Activity in Human Whole Blood
Springer Science+Business Media B.V. 2013 DOI
Karl-Erik Eilertsen,
Hanne K Mæhre,
Ida-Johanne Jensen,
hege Devold,
Jan Ole Olsen,
Reidun Klykken Lie
et al.:
A Wax Ester and Astaxanthin-Rich Extract from the Marine Copepod Calanus finmarchicus Attenuates Atherogenesis in Female Apolipoprotein E-Deficient Mice
Journal of Nutrition 2012 SAMMENDRAG / DOI
Bjarne Østerud
:
Tissue factor/TFPI and blood cells
Thrombosis Research 2012 DOI
Basavaraj Goolyam,
Mikhail Sovershaev,
Elena Egorina,
Franz Gruber,
Vladimir Bogdanov,
John T. Fallon
et al.:
Circulating monocytes mirror the imbalance in TF and TFPI expression in carotid atherosclerotic plaques with lipid-rich and calcified morphology
Thrombosis Research 2012 DOI
Basavaraj Manjunath Goolyam,
Jan Ole Olsen,
Bjarne Østerud,
John-Bjarne Hansen
:
Differential ability of tissue factor antibody clones on detection of tissue factor in blood cells and microparticles
Thrombosis Research 2012 DOI
Mikhail Sovershaev,
Elena Egorina,
Bjarne Østerud,
John-Bjarne Hansen
:
Evidence for direct transfer of tissue factor from monocytes to platelets in whole blood
Blood Coagulation and Fibrinolysis 2012 DOI
Emil Kostovski,
Anders Erik A Dahm,
Nina Iversen,
Nils Hjeltnes,
Bjarne Østerud,
Per Morten Sandset
et al.:
Melatonin stimulates release of tissue factor pathway inhibitor from the vascular endothelium
Blood Coagulation and Fibrinolysis 03. February 2011 DOI
Annica Hedberg,
Silje Fismen,
Kristin Andreassen Fenton,
Christopher Graham Fenton,
Bjarne Østerud,
Elin Mortensen
et al.:
Heparin Exerts a Dual Effect on Murine Lupus Nephritis by Enhancing Enzymatic Chromatin Degradation and Preventing Chromatin Binding in Glomerular Membranes
Arthritis and Rheumatism 2011 DOI
Elena Egorina,
Mikhail Sovershaev,
Vladimir Bogdanov,
TA Sovershaev,
John T. Fallon,
Natalya Seredkina
et al.:
Low thrombogenicity of calcified atherosclerotic plaques is associated with bone morphogenetic protein-2-dependent inhibition of tissue factor expression
Blood Coagulation and Fibrinolysis 2011 DOI
Mikhail Sovershaev,
Elena Egorina,
Vladimir Bogdanov,
Natalya Seredkina,
JT Fallon,
Andrey Yurjevich Valkov
et al.:
Bone morphogenetic protein-7 increases thrombogenicity of lipid-rich atherosclerotic plaques via activation of tissue factor
Thrombosis Research 2010 DOI
Bjarne Østerud,
Nadezhda Latysheva,
John Bjarne Hansen,
Omri Snir
:
“A rapid, sensitive, and specific assay to measure tissue factor activity based on chromogenic determination of thrombin generation”: reply
Journal of Thrombosis and Haemostasis 2023 DOI
Dana Meknas,
Bjarne Østerud
:
Bjarne går av med pensjon: – Jeg har levd et fantastisk liv, tross synlige odds mot meg
2020 FULLTEKST
Erik Waage Nielsen,
Bjarne Østerud
:
Measuring only pre-existing Factor VIIa
International Immunopharmacology 2020 DOI
Jon Nissen-Meyer,
Tore Skotland,
Bjarne Østerud,
Erik Boye
:
Improving scientific practice in sports-associated drug testing
The FEBS Journal 2019 DOI
Nils Olav Solum,
Frank Roger Brosstad,
Bjarne Østerud,
Kjell Steinar Sakariassen,
Geir Gogstad
:
Professor Helge Stormorken, 1922-2019
Journal of Thrombosis and Haemostasis 2019 DOI
Karianne Fredenfeldt Lind,
Jeanette hammer Andersen,
Trond Ø. Jørgensen,
Bjarne Østerud
:
Bioactivity profile of barettin - With special focus on anti-inflammatory, antioxidant and anticoagulant activities
UiT Norges arktiske universitet 2015 DATA
DI Feinstein,
Bjarne Østerud,
V. M. Rao
:
The partial thromboplastin time: reply
Journal of Thrombosis and Haemostasis 2014 DOI
Ida-Johanne Jensen,
Hanne K Mæhre,
Edel Oddny Elvevoll,
Bjarne Østerud,
Karl-Erik Eilertsen
:
Dietary enrichment with seal oil and taurine reduce hepatic expression of pro-inflammatory genes without affecting atherosclerosis in apolipoprotein E-deficient mice
2013
Hanne K Mæhre,
Ida-Johanne Jensen,
hege Devold,
Edel Oddny Elvevoll,
Bjarne Østerud,
Karl-Erik Eilertsen
:
Marine oil extracted from the copepod Calanus finmarchicus reduces aorta atherosclerosis in female apolipoprotein E-deficient mice
2013
DI Feinstein,
Bjarne Østerud,
LVM Rao
:
Samuel I. Rapaport, creator of the partial thromboplastin time and other landmark blood coagulation discoveries: 19 November 1921-20 December 2011 OBITUARY
Journal of Thrombosis and Haemostasis 2012 DOI
Basavaraj Manjunath Goolyam,
Bjarne Østerud,
John-Bjarne Hansen
:
Influence of different anticoagulants on monocyte procoagulant functions and monocyte-platelet aggregates formation
Journal of Thrombosis and Haemostasis 2012 DOI
M.G. Basavaraj,
Sigrid Kufaas Brækkan,
Ellen Elisabeth Brodin,
Bjarne Østerud,
John-Bjarne Hansen
:
Monocyte count and procoagulant functions are associated with risk of venous thromboembolism: the Tromso study
Journal of Thrombosis and Haemostasis 2011 DOI
Bjarne Østerud,
trine Lund,
hege Devold
:
The effect of platelet derived microparticles on genes in cells of whole blood and THP-1 cells
Journal of Thrombosis and Haemostasis 2011
Bjarne Østerud,
Edel Oddny Elvevoll
:
Dietary omega-3 fatty acids and risk of type 2 diabetes: lack of antioxidants?
American Journal of Clinical Nutrition 2011 DOI
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Research interests
- Tissue factor in blood cells
- Microparticles and inflammation
- Role of microparticles in thrombogenesis
- Marine bioprospecting/anti-inflammatory products
CV
Previous academic positions
ll/67-l2/67 University of Oslo, Department of Biochemistry, Oslo, Norway; Research Assistant
l/68- 2/7l USC Medical School, Department of Medicine, Los Angeles, Calif.; Research
Associate
3/7l- 5/72 Dept. of Microbiology, Dental Faculty, University of Oslo, Norway; Research
Stipendiate (NAVF)
6/72-l0/74 Institute of Medical Biology, Univ. of Tromsø, Tromsø, Norway; Research
Stipendiate (NAVF)
ll/74- 4/75 USC, Department of Medicine, Los Angeles, California; Research Associate
5/75- 9/78 Assistant Adjunct Professor of Medicine, University of California, San Diego,
Department of Medicine, La Jolla, Calif.
l0/78- 8/86 "Konsulent", Division of Clinical Chemistry, University Hospital, Tromsø, Norway
ll/79- 8/86 Professor II, Division of Clinical Chemistry, Institute of Medical Biology, University
of Tromsø, Tromsø, Norway
Supervision of Master and PhD-students
Supervised 17 Master students and supervision of 8 PhD-students as main supervisor and 11 as co-supervisor.
Total career publications
192 publications in peer-reviewed journals and 20 review articles and book chapters.