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Bilde av von Hofsten, Susannah
Bilde av von Hofsten, Susannah
Researcher Department of Medical Biology susannah.hofsten@uit.no Tromsø You can find me here

Susannah von Hofsten

Job description

I work as a researcher in the research group TBRG. I study breast cancer, and mainly focus on tumor microenvironment, proteoglycans, EMT, and metastasis. 

  • Shirin Porteymour, Saikat Das Sajib, Susannah von Hofsten, Atanaska I. Doncheva, Christina D. Bjørnvall, Beate Hegge et al.:
    Serglycin modulates inflammation and metabolism in macrophages
    iScience 10. March 2026 DOI / ARKIV
  • Susannah von Hofsten, Kristin Andreassen Fenton, Hege Lynum Pedersen :
    Human and Murine Toll-like Receptor-Driven Disease in Systemic Lupus Erythematosus
    International Journal of Molecular Sciences 2024 DOI / ARKIV
  • Susannah von Hofsten, Manuel K Langer, Katja Korelin, Synnøve Norvoll Magnussen, Dominik Ausbacher, Trude Anderssen et al.:
    Amphipathic barbiturates as marine product mimics with cytolytic and immunogenic effects on head and neck squamous cell carcinoma cell lines
    Frontiers in Pharmacology 30. March 2023 DOI / ARKIV
  • Eirik André Lindeløff Rustad, Susannah von Hofsten, Robin Kumar, Eirik Abrahamsen Lænsman, Gerd Berge, Natasa Skalko-Basnet :
    The pH-Responsive Liposomes—The Effect of PEGylation on Release Kinetics and Cellular Uptake in Glioblastoma Cells
    Pharmaceutics 2022 DOI / ARKIV
  • Susannah von Hofsten, Marianne Hagensen Paulsen, Synnøve Magnussen, Dominik Ausbacher, Mathias Kranz, Annette Bayer et al.:
    The marine natural product mimic MPM-1 is cytolytic and induces DAMP release from human cancer cell lines
    Scientific Reports 2022 DOI / ARKIV
  • Ingebrigt Sylte, Rangita Dawadi, Nabin Malla, Susannah von Hofsten, Tra-Mi Nguyen, Ann Iren Solli et al.:
    The selectivity of galardin and an azasugar-based hydroxamate compound for human Matrix metalloproteases and bacterial metalloproteases
    PLOS ONE 2018 DOI / ARKIV
  • Aud-Malin Karlsson Hovd, Premasany Kanapathippilai, Thea Ekrem Skagen, anita Ursvik, Stine Figenschau, Susannah von Hofsten et al.:
    Early imiquimod-induced onset of disease in lupus-prone NZBW-F1 mice
    2025 ARKIV
  • Kjersti Sellæg, Susannah von Hofsten, Saikat Das Sajib, Karoline Sollid Evensen, Beate Hegge, Margrethe Similä Vasslag et al.:
    Hva gjør en kreftforsker?
    2025 ARKIV
  • Synnøve Norvoll Magnussen, Kjersti Sellæg, Susannah Beatrice von Hofsten, Beate Hegge, Tonje Nygård Lillevik, Karoline Sollid Evensen et al.:
    Hva gjør en kreftforsker?
    2024 ARKIV
  • Kjersti Sellæg, Tetyana Voloshyna, Saikat Das Sajib, Tonje Nygård Lillevik, Susannah Beatrice von Hofsten, Karoline Sollid Evensen et al.:
    Urinlaben
    2024 ARKIV
  • Kjersti Sellæg, Susannah Beatrice von Hofsten, Anne Kristin McLaren Berge, Lennart Maximilian van Ligtenberg, Marcus Moe Mauseth, Athanasios Kournoutis et al.:
    Autofagi: cellenes spareblussmodus
    2023 ARKIV
  • May-Britt Five, gerd Berge, Susannah von Hofsten, Kjersti Sellæg :
    Medisiner fra havet
    2023 ARKIV
  • Kjersti Sellæg, Susannah von Hofsten, Nikoline Lander Rasmussen, May-Britt Five :
    Fisking etter fremtidens medisiner - Havet er fullt av mysterier, bli med og let etter nyttige stoffer!
    2022 ARKIV
  • Susannah von Hofsten :
    Hvordan drepe kreftceller - Med inspirasjon fra marine naturprodukter
    2022 ARKIV
  • Susannah von Hofsten, Marianne Hagensen Paulsen, Manuel K Langer, Synnøve Norvoll Magnussen, Dominik Ausbacher, Annette Bayer et al.:
    A Compound Inspired by Arctic Marine Animals Kills Cancer Cells in vitro and in vivo
    2022 ARKIV
  • Susannah von Hofsten, Synnøve Norvoll Magnussen, Dominik Ausbacher, Marianne Hagensen Paulsen, Annette Bayer, Morten B. Strøm et al.:
    The Marine Natural Product Mimic MHP88 Shows Anticancer Activity and has the Potential to Cause Immunogenic Cell Death
    2020 ARKIV

    • The 50 latest publications is shown on this page. See all publications in NVA here →

    Research interests

    • Breast cancer
    • Tumor micro environment
    • Immunology
    • Autoimmunity and tolerance
    • Systemic lupus erythematosus
    • Women's health

    Teaching

    Previous teaching:

    • HEL-0700: assignment in academic writing
    • TPL-1010/TANN-114: immunology for dental nurse students
    • MBI-2010: co-supervisor for one bachelor student in biomedicine
    • MBI-3911: co-supervisor for one master student in biomedicine
    • ODO-2008: seminars in immunology
    ResearchGate
    ORCID: https://orcid.org/0000-0002-4079-0655

    Member of research group / centre

    Tumor Biology Research Group   English content

    Member of project

    Human Lupus Nephritis Breast cancer metastasis

    CV

    2024 - Researcher, TBRG, IMB, UiT. PI: Erik Knutsen

    2023 - 2024 Researcher, RAMP, IMB, UiT. PI: Hege Lynum Pedersen

    2019 - 2023 PhD student, TBRG, IMB, UiT. Title of thesis: Anticancer activity of amphipathic barbiturates.

    • 2021-2022 Research stay (4 months) in Professor Tuula Salo's lab at the Department of Oral and Maxillofacial Diseases, University of Helsinki, Finland.

    2018 - 2019 Engineer for a MABIT financed project: Exploration of an anticancer marine natural product mimic.

    2016 - 2018 Master in biomedicine from UiT. Title of Master thesis: Exploring the in vitro expansion of CD4 T cells – For improved culturing of CD4 T cells linked to FNAIT.

    2013 - 2016 Bachelor in biomedicine from UiT. Title of bachelor thesis: Inhibition of metalloproteinases and the differences within the binding site in human and bacterial zinc metalloproteinases.

    2012 - 2013 One year study program in French language and culture from IEFE, Université Paul Valéry Montpellier III, France.

    2009 - 2012 High school, Kongsbakken VGS

    MH øst L8.227


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