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Preclinical Efficacy of Cabazitaxel Loaded Poly(2-alkyl cyanoacrylate) Nanoparticle Variants
International Journal of Nanomedicine 2024
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Deep learning for automated scoring of immunohistochemically stained tumour tissue sections – Validation across tumour types based on patient outcomes
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The SRC-family serves as a therapeutic target in triple negative breast cancer with acquired resistance to chemotherapy
British Journal of Cancer 2024
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Caroline Elisabeth Nunes-Xavier,
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The expression pattern of pyruvate dehydrogenase kinases predicts prognosis and correlates with immune exhaustion in clear cell renal cell carcinoma
Gisella Figlioli,
Amandine Billaud,
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FANCM missense variants and breast cancer risk: a case-control association study of 75,156 European women
European Journal of Human Genetics 2023
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Salim Ghannoum,
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A combined experimental-computational approach uncovers a role for the Golgi matrix protein Giantin in breast cancer progression
PLoS Computational Biology 2023
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Solveig Pettersen,
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Breast cancer patient-derived explant cultures recapitulate in vivo drug responses
Lisa Gregusson Svartdal,
Mads Haugen,
Vesa Hongisto,
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Vessela N. Kristensen
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High-throughput screen in vitro identifies dasatinib as a candidate for combinatorial treatment with HER2-targeting drugs in breast cancer
Mads Haugen,
Hedda von der Lippe Gythfeldt,
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Liver X receptors induce antiproliferative effects in basal-like breast cancer
Vigdis Nygaard,
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Bjørn von Gohren Edwin,
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A PRRX1 Signature Identifies TIM-3 and VISTA as Potential Immune Checkpoint Targets in a Subgroup of Microsatellite Stable Colorectal Cancer Liver Metastases
Cancer Research Communications 2023
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Erik Knutsen,
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Identification of a core EMT signature that separates basal-like breast cancers into partial- and post-EMT subtypes
Marta Sølvi Nyakas,
Karianne Giller Fleten,
Mads Haugland Haugen,
Nikolai Engedal,
Christina Sveen,
Inger Nina Farstad
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AXL inhibition improves BRAF-targeted treatment in melanoma
Caroline Elisabeth Nunes-Xavier,
Maite Emaldi,
Ingrid Jenny Guldvik,
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Kristin Austlid Tasken,
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Correlation of expression of Major Vault Protein with androgen receptor and immune checkpoint protein B7-H3, and with poor prognosis in prostate cancer
Pathology, Research and Practice 2022
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Anne Hansen Ree,
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Cost-effectiveness of molecularly matched off-label therapies for end-stage cancer – the MetAction precision medicine study
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Mads Haugland Haugen,
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miR-101-5p Acts as a Tumor Suppressor in HER2-Positive Breast Cancer Cells and Improves Targeted Therapy
Breast Cancer: Targets and Therapy 2022
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Caroline Elisabeth Nunes-Xavier,
Janire Mingo,
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Karine Flem-Karlsen,
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Heterogeneous Expression and Subcellular Localization of Pyruvate Dehydrogenase Complex in Prostate Cancer
Frontiers in Oncology 2022
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Elisa Fiorito,
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Strategies to inhibit FGFR4 V550L-driven rhabdomyosarcoma
British Journal of Cancer 2022
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Margherita Ambrosini,
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ALK Inhibitors in Patients with ALK Fusion-Positive GI Cancers: An International Data Set and a Molecular Case Series
JCO Precision Oncology (JCO PO) 2022
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Sunniva Bjørklund,
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Subtype and cell type specific expression of lncRNAs provide insight into breast cancer
Marta Tellez Gabriel,
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Serglycin is Involved in TGF-β induced epithelial-mesenchymal transition and is highly expressed by immune cells in breast cancer tissue
Frontiers in Oncology 14. April 2022
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Mateusz Adam Krzyscik,
Malgorzata Zakrzewska,
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Fibroblast growth factor 2 conjugated with monomethyl auristatin E inhibits tumor growth in a mouse model
Remya Valsalakumari,
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Mechanism of cellular uptake and cytotoxicity of paclitaxel loaded lipid nanocapsules in breast cancer cells.
International Journal of Pharmaceutics 2021
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Abhilash D. Pandya,
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Biodistribution of Poly(alkyl cyanoacrylate) Nanoparticles in Mice and Effect on Tumor Infiltration of Macrophages into a Patient-Derived Breast Cancer Xenograft
Sigurdur Karvelsson,
Qiong Wang,
Bylgja Hilmarsdòttir,
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Argininosuccinate lyase is a metabolic vulnerability in breast development and cancer
npj Systems Biology and Applications 2021
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Sigurdur Karvelsson,
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EMT-derived alterations in glutamine metabolism sensitize mesenchymal breast cells to mTOR inhibition
Molecular Cancer Research 05. June 2021
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Caroline Elisabeth Nunes-Xavier,
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Immune checkpoint B7-H3 protein expression is associated with poor outcome and androgen receptor status in prostate cancer
Karianne Giller Fleten,
Jacobus Johannes Eksteen,
Brynjar Mauseth,
Ketil André Camilio,
Terje Vasskog,
Baldur Sveinbjørnsson
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Oncolytic peptides DTT-205 and DTT-304 induce complete regression and protective immune response in experimental murine colorectal cancer
Mads Haugland Haugen,
Ole Christian Lingjærde,
Ingrid Hedenfalk,
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Elin Borgen,
Niklas Loman
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Protein signature predicts response to neoadjuvant treatment with chemotherapy and bevacizumab in HER2-negative breast cancers
Henrik Aasrum Svendsen,
Torstein Ragnar Meling,
Vigdis Nygaard,
Stein Waagene,
Hege Elisabeth Giercksky Russnes,
Siri Juell
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Novel human melanoma brain metastasis models in athymic nude fox1nu mice: Site-specific metastasis patterns reflecting their clinical origin
Vegar Johansen Dagenborg,
Serena Marshall,
Krzysztof Grzyb,
Åsmund Avdem Fretland,
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Gunhild Mari Mælandsmo
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Low Concordance Between T-Cell Densities in Matched Primary Tumors and Liver Metastases in Microsatellite Stable Colorectal Cancer
Anna Barkovskaya,
Craig Goodwin,
Kotryna Seip,
Bylgja Hilmarsdòttir,
Solveig Pettersen,
Clint Stalnecker
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Detection of phenotype-specific therapeutic vulnerabilities in breast cells using a CRISPR loss-of-function screen
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Mads Haugland Haugen
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Trafficking of full-length and N-terminally truncated cathepsin B in human colorectal carcinoma cells
Applied Sciences 2021
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Breast cancer metastasis: immune profiling of lymph nodes reveals exhaustion of effector T cells and immunosuppression
Xing Yi Woo,
Jessica Giordano,
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Roebi de Bruijn
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Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
Lisa Gregusson Svartdal Normann,
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Suvi-Katri Leivonen,
Mads Haugland Haugen,
Vesa Hongisto,
Vessela N. Kristensen
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MicroRNA in combination with HER2-targeting drugs reduces breast cancer cell viability in vitro
Abhilash D. Pandya,
Anders Øverbye,
Priyanka Saharia,
Vivek S. Gaware,
Håkon Høgset,
Már Masson
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Drug-Loaded Photosensitizer-Chitosan Nanoparticles for Combinatorial Chemo- and Photodynamic-Therapy of Cancer
Karine Flem-Karlsen,
Marta Sølvi Nyakas,
Inger Nina Farstad,
Erin McFadden,
Patrik Vernhoff,
Kari Dolven Jacobsen
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Soluble AXL as a marker of disease progression and survival in melanoma
Anne Hansen Ree,
Vigdis Nygaard,
Kjetil Boye Pedersen,
Daniel Heinrich,
Svein Dueland,
Inger Riise Bergheim
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Molecularly matched therapy in the context of sensitivity, resistance, and safety; patient outcomes in end-stage cancer?the MetAction study
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Miriam Ragle Aure,
Silje Nord,
Silje Fismen,
Kenneth Bowitz Larsen
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The expression of the long NEAT1_2 isoform is associated with human epidermal growth factor receptor 2-positive breast cancers
Jingjing Liu,
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Vessela N. Kristensen
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Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk
Vegar Johansen Dagenborg,
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Krzysztof Grzyb,
Åsmund Avdem Fretland,
Marius Lund-Iversen,
Gunhild Mari Mælandsmo
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Low concordance between T-cell densities in matched primary tumors and liver metastases in microsatellite stable colorectal cancer
Frontiers in Oncology 2020
Sophie Sarah Steinhaeuser,
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Ottar Rolfsson
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ECM1 secreted by HER2-overexpressing breast cancer cells promotes formation of a vascular niche accelerating cancer cell migration and invasion
Laboratory Investigation 2020
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Targeting Telomerase with an HLA Class II-Restricted TCR for Cancer Immunotherapy
Molecular Therapy 2020
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Protein kinase C isozymes associated with relapse free survival in non-small cell lung cancer patients
Frontiers in Oncology 25. November 2020
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Physicochemical characterization, toxicity and in vivo biodistribution studies of a discoidal, lipid-based drug delivery vehicle: Lipodisq nanoparticles containing doxorubicin
Journal of Biomedical Nanotechnology 2020
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O-GlcNAc Transferase Inhibition Differentially Affects Breast Cancer Subtypes
Ketil Andre Camilio,
Mengyu Wang,
Brynjar Mauseth,
Stein Waagene,
Gunnar Kvalheim,
Øystein Rekdal
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Combining the oncolytic peptide LTX-315 with doxorubicin demonstrates therapeutic potential in a triple-negative breast cancer model
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Øystein Fodstad
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p38 MAPK activation through B7-H3-mediated DUSP10 repression promotes chemoresistance