Jaione Simón-Santamaría
Job description
Advice, development of methods within cell biology, daily laboratory routines (cell work, Immunostaining, qPCR,...), laboratory management, suppervision and training, HSE.
Javier Sánchez Romano,
Jaione Simon-Santamaria,
Peter Anthony McCourt,
Bård Helge Smedsrød,
Kim Erlend Mortensen,
Antonia Sagona
et al.:
Liver sinusoidal cells eliminate blood-borne phage K1F
Sabin Bhandari,
Ingelin Kyrrestad Karlstrøm,
Jaione Simon-Santamaria,
Ruomei Li,
Karolina Joanna Szafranska,
Gianina Aurica Dumitriu
et al.:
Mouse liver sinusoidal endothelial cell responses to the glucocorticoid receptor agonist dexamethasone
Ingelin Kyrrestad Karlstrøm,
Anett Kristin Larsen,
Javier Sanchez Romano,
Jaione Santamaria Simon,
Ruomei Li,
Karen Kristine Sørensen
:
Infection of liver sinusoidal endothelial cells with Muromegalovirus muridbeta1 involves binding to neuropilin-1 and is dynamin-dependent
Milton Boaheng Antewi,
Gianina Aurica Dumitriu,
Jaione Santamaria Simon,
Javier Sanchez Romano,
Ruomei Li,
Bård Smedsrød
et al.:
Liver sinusoidal endothelial cells show reduced scavenger function and downregulation of Fc gamma receptor IIb, yet maintain a preserved fenestration in the Glmp gt/gt mouse model of slowly progressing liver fibrosis
Christopher Florian Holte,
Karolina Joanna Szafranska,
Larissa Dorothea Kruse,
Jaione Simon-Santamaria,
Ruomei Li,
Dmitri Svistounov
et al.:
Highly oxidized albumin is cleared by liver sinusoidal endothelial cells via the receptors stabilin-1 and -2
Ruomei Li,
Sabin Bhandari,
Inigo Zubiavrre Martinez,
Jack-Ansgar Bruun,
Ilona Halva Urbarova,
Bård Smedsrød
et al.:
Changes in the proteome and secretome of rat liver sinusoidal endothelial cells during early primary culture and effects of dexamethasone
Anett Kristin Larsen,
Jaione Simon-Santamaria,
kjetil helge Elvevold,
Bo Gøran Ericzon,
Kim Erlend Mortensen,
Peter Anthony McCourt
et al.:
Autofluorescence in freshly isolated adult human liver sinusoidal cells
Sabin Bhandari,
Ruomei Li,
Jaione Simon-Santamaria,
Peter Anthony McCourt,
Steinar Daae Johansen,
Bård Smedsrød
et al.:
Transcriptome and proteome profiling reveal complementary scavenger and immune features of rat liver sinusoidal endothelial cells and liver macrophages
Bo Wold Nilsen,
Jaione Simon-Santamaria,
Ulf Thore Ørtengren,
Einar Jensen,
Jack-Ansgar Bruun,
Vibeke Barman Michelsen
et al.:
Dose- and time-dependent effects of triethylene glycol dimethacrylate on the proteome of human THP-1 monocytes
Jacobus Johannes Eksteen,
Dominik Ausbacher,
Jaione Simon-Santamaria,
Trine Stiberg,
Cristiane de Albuquerque Cavalcanti Jacobsen,
Imin Wushur
et al.:
Iterative design and in vivo evaluation of an oncolytic antilymphoma peptide
Journal of Medicinal Chemistry 2016 DOI
Bo Wold Nilsen,
Ulf Thore Ørtengren,
Jaione Simon-Santamaria,
Karen Kristine Sørensen,
Vibeke Barman Michelsen
:
Methods and terminology used in cell-culture studies of low-dose effects of matrix constituents of polymer resin-based dental materials
European Journal of Oral Sciences 2016 DOI
Karen Kristine Sørensen,
Jaione Simon-Santamaria,
Robert S. McCuskey,
Bård Smedsrød
:
Liver sinusoidal endothelial cells
Comprehensive Physiology 2015 DOI
Jaione Simon-Santamaria,
Christine Hanssen Rinaldo,
Piotr Kardas,
Ruomei Li,
Ivana Malovic,
kjetil helge Elvevold
et al.:
Efficient uptake of blood-borne BK and JC polyomavirus-like particles in endothelial cells of liver sinusoids and renal vasa recta
Agnes Rasmuson,
Anna Kock,
Ole-Martin Fuskevåg,
Björn Kruspig,
Jaione Simon-Santamaria,
Vladimir Gogvadze
et al.:
Autocrine Prostaglandin E-2 Signaling Promotes Tumor Cell Survival and Proliferation in Childhood Neuroblastoma
Jaione Simon,
Ivana Malovic,
Alessandra Warren,
Ana Oteiza,
David LeCouteur,
Bård Smedsrød
et al.:
Age-Related Changes in Scavenger Receptor-Mediated Endocytosis in Rat Liver Sinusoidal Endothelial Cells
The journals of gerontology. Series A, Biological sciences and medical sciences 2010 DOI
kjetil helge Elvevold,
Jaione Simon,
hege Hasvold,
Peter Anthony Mccourt,
Bård Smedsrød,
Karen Sørensen
:
Liver Sinusoidal Endothelial Cells Depend on Mannose Receptor-Mediated Recruitment of Lysosomal Enzymes for Normal Degradation Capacity
Hepatology 2008 DOI
Armas Maria Montserrat Martin,
Jaione Simon-Santamaria,
Ingvild Pettersen,
Ugo Lionel Moens,
Bård Smedsrød,
Baldur Sveinbjørnsson
:
Toll-like receptor 9 (TLR9) is present in murine liver sinusoidal endothelial cells (LSECs) and mediates the effect of CpG-oligonucleotides
Journal of Hepatology 2006
Ingelin Kyrrestad Karlstrøm,
Anett Kristin Larsen,
Javier Sanchez Romano,
Jaione Santamaria Simon,
Ruomei Li,
Karen Kristine Sørensen
:
The dynamin-inhibitor dynasore blocks cytomegalovirus infection in primary mouse liver sinusoidal endothelial cells
2023
Javier Sanchez Romano,
Jaione Santamaria Simon,
Peter Anthony Gerard Mccourt,
Christopher Florian Holte,
Bård Smedsrød,
Antonia Sagona
et al.:
Rapid blood clearance of phage K1F-GFP is mediated by the liver and executed by Kupffer cells and liver sinusoidal endothelial cells in collaboration
2023
Anett Kristin Larsen,
Javier Sanchez Romano,
Jaione Santamaria Simon,
Kim Erlend Mortensen,
Ingelin Kyrrestad Karlstrøm,
Eirik Abrahamsen Lænsman
et al.:
Liver sinusoidal scavenger cells eliminate betaherpesvirus from the blood stream.
Journal of Hepatology 2023 DOI
Ingelin Kyrrestad Karlstrøm,
Anett Kristin Larsen,
Javier Sanchez Romano,
Jaione Santamaria Simon,
Ruomei Li,
Karen Kristine Sørensen
:
Dynamin-inhibitors dynasore and MitMAB block muromegalovirus muridbeta1 infection in liver sinusoidal endothelial cells.
2023
Ingelin Kyrrestad,
Javier Sanchez Romano,
Anett Kristin Larsen,
Ruomei Li,
Jaione Simon-Santamaria,
Kenneth Bowitz Larsen
et al.:
Effect of dynamin inhibitor dynasore on primary mouse liver sinusoidal endothelial cells (LSEC)
2022
Javier Sanchez Romano,
Anett Kristin Larsen,
Jaione Simon-Santamaria,
Cristina Ionica Øie,
Bård Smedsrød,
Peter Anthony McCourt
et al.:
The role of scavenger endothelial cells in bacteriophage pharmacokinetics
2022
Javier Sanchez Romano,
Anett Kristin Larsen,
Jaione Simon-Santamaria,
Cristina Ionica Øie,
Bård Smedsrød,
Peter Anthony McCourt
et al.:
The role of scavenger endothelial cells in bacteriophage pharmacokinetics
2022
Anett Kristin Larsen,
Javier Sanchez Romano,
Jaione Simon-Santamaria,
Kim Erlend Mortensen,
Bo Gøran Ericzon,
Peter Anthony McCourt
et al.:
Role of liver sinusoidal endothelial cells in elimination of virus
2022
Anett Kristin Larsen,
Javier Sanchez Romano,
Eirik Abrahamsen Lænsman,
Anne Lotte Vada Hatlegjerde,
Jaione Simon-Santamaria,
Kim Erlend Mortensen
et al.:
Liver sinusoidal scavenger cells eliminate betaherpesvirus from the blood stream
2022
Sabin Bhandari,
Ruomei Li,
Ingelin Kyrrestad,
Jack-Ansgar Bruun,
Ilona Urbarova,
Bård Smedsrød
et al.:
Effect of glucocorticoids on liver sinusoidal endothelial cells in vitro
2019
Ingelin Kyrrestad,
Ruomei Li,
Sabin Bhandari,
Jaione Simon-Santamaria,
Bård Smedsrød,
Karen Kristine Sørensen
:
A protocol for in vitro toxicity studies in liver sinusoidal endothelial cells
2019
Anett Kristin Larsen,
Jaione Simon-Santamaria,
kjetil helge Elvevold,
Bo G. Ericzon,
Bård Smedsrød,
Karen Kristine Sørensen
:
Autofluorescence in freshly isolated adult human liver sinusoidal cells
2019
Javier Sanchez Romano,
Anett Kristin Larsen,
kjetil helge Elvevold,
Christopher Florian Holte,
Jaione Simon-Santamaria,
Hans H. Hirsch
et al.:
SECVIR - The role of scavenger endothelial cells in elimination of virus
2019
Sabin Bhandari,
Ruomei Li,
Jaione Simon-Santamaria,
Peter Anthony McCourt,
Steinar Daae Johansen,
Bård Smedsrød
et al.:
The liver sinusoidal endothelial cell – an endothelial cell with a macrophage-like identity
2017
Ruomei Li,
Jaione Simon-Santamaria,
Sabin Bhandari,
Jack-Ansgar Bruun,
Ilona Urbarova,
Bård Smedsrød
et al.:
Phenotypic changes in rat liver sinusoidal endothelial cells during early stages of in vitro culture
2017
Bo Wold Nilsen,
Ulf Thore Ørtengren,
Jaione Simon-Santamaria,
Karen Kristine Sørensen,
Vibeke Barman Michelsen
:
Low-grade toxicity of matrix constituents of polymer resin based dental materials - A review of terminology and methods
2016
Jaione Simon-Santamaria,
Ruomei Li,
Sabin Bhandari,
Jack-Ansgar Bruun,
Bård Smedsrød,
Inigo Zubiavrre Martinez
et al.:
Secretome of the liver sinusoidal endothelial cell
2016
Sabin Bhandari,
Ruomei Li,
Jaione Simon-Santamaria,
Peter Anthony McCourt,
Steinar Daae Johansen,
Bård Smedsrød
et al.:
Next generation deep sequencing of rat liver
sinusoidal endothelial cell and Kupffer cell
transcriptomes suggests functional
complementarity
2016
Jaione Simon-Santamaria,
Christine H Rinaldo,
Piotr Kardas,
Ruomei Li,
Ivana Malovic,
Kjetil H. Elvevold
et al.:
Role of scavenger endothelial cells in polyomavirus JC and BK clearance
2014
Jaione Simon-Santamaria,
Ruomei Li,
Piotr Kardas,
Ivana Malovic,
Kjetil H. Elvevold,
Peter Anthony McCourt
et al.:
Role of liver sinusoidal endothelial cells in blood clearance of polyomavirus BK and JC
2012
Jaione Simon
:
Pattern recognition receptors in liver sinusoidal endothelial cells: Roles in the innate immune system and scavenger functions
UiT Norges arktiske universitet 2011
Jaione Simon-Santamaria,
Ivana Malovic,
Alessandra Warren,
Ana Oteiza,
David LeCouteur,
Bård Smedsrød
et al.:
Endocytic activity of liver sinusoidal endothelial cells in aging
2010
Jaione Simon,
Ivana Malovic,
A Warren,
Ana Oteiza,
D Le Couteur,
Bård Smedsrød
et al.:
Age-related changes in scavenger receptor mediated endocytosis in rat liver sinusoidal endothelial cells. Abstract book p.22
2008
kjetil helge Elvevold,
Jaione Simon Santamaria,
H Hasvold,
Bård Smedsrød,
Karen Sørensen
:
Liver sinusoidal endothelial cells depend on mannose receptor mediated endocytic recruitment of lysosomal enzymes for normal degradation capacity
2006
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Research interests
Role of Liver sinusoidal endothelial cells in innate immunity. Cell culture techniques, qPCR, good laboratory practice.
