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Bilde av Ahlen, Maria Therese
Bilde av Ahlen, Maria Therese
Associate Professor Department of Medical Biology maria.t.ahlen@uit.no Tromsø

Maria Therese Ahlen

Job description

Scientist and lecturer in Immunology. 
Member of Immunology Reasearch Group at UiT The Arctic University of Norway

Researcher at Department of Laboratory medicine, UNN and the Norwegian National Unit for Platelet Immunology. www.unn.no/nnupi

 


 

 

  • Romy Pothof, Elske M van den Akker-van Marle, Thijs W de Vos, Heidi Tiller, James B Bussel, Maria Therese Ahlen et al.:
    Rising to the challenge: an international Delphi consensus study on fetal and neonatal alloimmune thrombocytopenia
    The Lancet Haematology 2025 DOI
  • Nora Hersoug Nedberg, Mona Nystad, Maria Therese Ahlen, eirin listau Bertelsen, Katarzyna Guz, Małgorzata Uhrynowska et al.:
    Placenta-associated biomarkers and pregnancy outcome in HPA-1a alloimmunization: A prospective cohort study
    Placenta 2024 DOI / ARKIV
  • Tina Coucheron, Malgorzata Uhrynowska, Katarzyna Guz, Agnieszka Orzińska, Marzena Debska, Agnieszka Gierszon et al.:
    What's with the boys? Lower birth weight in boys from HPA-1a alloimmunized pregnancies – New insights from a large prospective screening study in Poland
    Journal of Reproductive Immunology 2023 DOI / ARKIV
  • Thor Ueland, Ingvild Hausberg Sørvoll, Trude Victoria Mørtberg, Tuva Børresdatter Dahl, Tøri Vigeland Lerum, Annika Elisabet Michelsen et al.:
    Anti-PF4/polyanion antibodies in COVID-19 patients are associated with disease severity and pulmonary pathology
    Platelets 2022 DOI / ARKIV
  • Nina Haagenrud Schultz, Arne Vasli Søraas, Ingvild Hausberg Sørvoll, Cigdem Ahaein Akkøk, Annette Vetlesen, Bhamra Singh Jagjit et al.:
    Vaccine associated benign headache and cutaneous hemorrhage after ChAdOx1 nCoV-19 vaccine: A cohort study
    Journal of Stroke & Cerebrovascular Diseases 2022 DOI / ARKIV
  • Siw Leiknes Ernstsen, Maria Therese Ahlen, Tiril Johansen, Eirin Listau Bertelsen, Jens Kjeldsen-Kragh, Heidi Tiller :
    Antenatal intravenous immunoglobulins in pregnancies at risk of fetal and neonatal alloimmune thrombocytopenia: comparison of neonatal outcome in treated and nontreated pregnancies
    American Journal of Obstetrics and Gynecology 2022 DOI / ARKIV
  • Ingvild Jenssen Lægreid, Mats Irgen Olsen, Jon Inge Harr, Renathe Henriksen Grønli, Trude Victoria Mørtberg, Siw Leiknes Ernstsen et al.:
    Acute drug-induced immune thrombocytopenia - A work of articaine
    Transfusion 2022 DOI
  • Lamya Samir Noori Garabet, Anna Maria Eriksson, Eirik Tjønnfjord, Xueyan Cui, Magnus Kringstad Olsen, Hege Jacobsen et al.:
    SARS-CoV-2 vaccines are not associated with hypercoagulability in apparently healthy people
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2022 DOI / ARKIV
  • Trude Victoria Mørtberg, Huiying Zhi, Gestur Vidarsson, Stian Foss, Suzanne Lissenberg-Thunnissen, Manfred Wuhrer et al.:
    Prevention of Fetal/Neonatal Alloimmune Thrombocytopenia in Mice: Biochemical and Cell Biological Characterization of Isoforms of a Human Monoclonal Antibody
    ImmunoHorizons 2022 DOI / ARKIV
  • Silje Johansen, Ingvild Jenssen Lægreid, Siw Leiknes Ernstsen, Nessar Ahmad Azrakhsh, Astrid Marta Olsnes Kittang, Roald Lindås et al.:
    Thrombosis and thrombocytopenia after HPV vaccination
    Journal of Thrombosis and Haemostasis 2021 DOI / ARKIV
  • Ingvild Hausberg Sørvoll, Kjersti Daae Horvei, Siw Leiknes Ernstsen, Ingvild Jenssen Lægreid, Svetlana Lund, Renathe Henriksen Grønli et al.:
    An observational study to identify the prevalence of thrombocytopenia and anti-PF4/polyanion antibodies in Norwegian health care workers after COVID-19 vaccination
    Journal of Thrombosis and Haemostasis 2021 DOI / ARKIV
  • Ishac Nazy, Ulrich J. Sachs, Donald M. Arnold, Steven E. McKenzie, Phil Choi, Karina Althaus et al.:
    Recommendations for the clinical and laboratory diagnosis of VITT against COVID-19: Communication from the ISTH SSC Subcommittee on Platelet Immunology
    Journal of Thrombosis and Haemostasis 2021 DOI
  • Huiying Zhi, Maria Therese Ahlen, Bjørn Skogen, Debra K. Newman, Peter J. Newman :
    Preclinical evaluation of immunotherapeutic regimens for fetal/neonatal alloimmune thrombocytopenia
    Blood Advances 2021 DOI
  • Nina Haagenrud Schultz, Ingvild Hausberg Sørvoll, Annika Michelsen, Ludvig Andre Munthe, Fridtjof Lund-Johansen, Maria Therese Ahlen et al.:
    Thrombosis and thrombocytopenia after CHADOX1 NCoV-19 vaccination
    New England Journal of Medicine 2021 DOI / ARKIV
  • Maria Therese Ahlen, Gøril Heide, Anne Husebekk, Bjørn Skogen, Jens Kjeldsen-Kragh, Tor Brynjar Stuge :
    The prevalence of HPA-1a alloimmunization and the potential risk of FNAIT depend on both the DRB3*01:01 allele and associated DR-DQ haplotypes
    Scandinavian Journal of Immunology 16. April 2020 DOI / ARKIV
  • Trude Victoria Rasmussen, Maria Therese Ahlen :
    Murine models for studying treatment, prevention and pathogenesis of FNAIT
    Transfusion and Apheresis Science 2020 DOI / ARKIV
  • Jens Kjeldsen-Kragh, Maria Therese Ahlen :
    Foetal and neonatal alloimmune thrombocytopenia - The role of the HLA-DRB3*01:01 allele for HPA-1a-immunisation and foetal/neonatal outcome
    Transfusion and Apheresis Science 2020 DOI
  • Heidi Tiller, Maria Therese Ahlen, Cigdem Ahaein Akkøk, Anne Husebekk :
    Fetal and neonatal alloimmune thrombocytopenia - The Norwegian management model
    Transfusion and Apheresis Science 2019 DOI / ARKIV
  • Agnieszka Orzińska, Katarzyna Guz, Małgorzata Uhrynowska, Marzena Dȩbska, Michal Mikula, Jerzy Ostrowski et al.:
    Noninvasive prenatal HPA-1 typing in HPA-1a negative pregnancies selected in the Polish PREVFNAIT screening program
    Transfusion 2018 DOI
  • Huiying Zhi, Maria Therese Ahlen, Aye Myat Myat Thinn, Hartmut Weiler, Brian R. Curtis, Bjørn Skogen et al.:
    High-resolutionmappingofthepolyclonalimmuneresponsetothehuman platelet alloantigen HPA-1a (PlA1)
    Blood Advances 2018 DOI
  • Heidi Tiller, Anne Husebekk, Maria Therese Ahlen, Tor Brynjar Stuge, Bjørn Ragnar Skogen :
    Current perspectives on fetal and neonatal alloimmune thrombocytopenia - Increasing clinical concerns and new treatment opportunities
    International Journal of Women's Health 2017 DOI / ARKIV
  • Jesper Dahl, Erle Refsum, Maria Therese Ahlen, Torstein Egeland, Tore Jensen, Marte K Viken et al.:
    Unraveling the role of maternal anti-HLA class I antibodies in fetal and neonatal thrombocytopenia?Antibody specificity analysis using epitope data
    Journal of Reproductive Immunology 2017 DOI
  • Maria Therese Ahlen, Anne Husebekk, Ida Løken Killie, Bjørn Ragnar Skogen, Tor Brynjar Stuge :
    T cell responses to human platelet antigen-1a involve a unique form of indirect allorecognition
    JCI Insight 2016 DOI
  • Anne Husebekk, M El Ekiaby, G Gorgy, Mette Kjær Killie, Camilla Uhlin Hansen, Wahida Salma et al.:
    Foetal/neonatal alloimmune thrombocytopenia in Egypt; human platelet antigen genotype frequencies and antibody detection and follow-up in pregnancies
    Transfusion and Apheresis Science 2012 DOI
  • Maria Therese Ahlen, Anne Husebekk, Mette Kjær Killie, Jens Kjeldsen-Kragh, Martin L. Olsson, Bjørn Ragnar Skogen :
    The Development of Severe Neonatal Alloimmune Thrombocytopenia due to Anti-HPA-1a Antibodies Is Correlated to Maternal ABO Genotypes
    Clinical & Developmental Immunology 2012 DOI / ARKIV / FULLTEKST
  • Tor Brynjar Stuge, Bjørn Ragnar Skogen, Maria Therese Ahlen, Anne Husebekk, SJ Urbaniak, H Bessos :
    The Cellular immunobiology associated with fetal and neonatal alloimmune thrombocytopenia
    Transfusion and Apheresis Science 2011 DOI
  • Bjørn Ragnar Skogen, Mette Kjær Killie, Jens Kjeldsen-Kragh, Maria Therese Ahlen, Heidi Tiller, Tor Brynjar Stuge et al.:
    Reconsidering fetal and neonatal alloimmune thrombocytopenia with a focus on screening and prevention
    Expert Review of Hematology 2010 DOI
  • Anne Husebekk, Maria Therese Ahlen, Mette Kjær Killie, Heidi Tiller, Mariana Eksteen, Ida Løken Killie et al.:
    Blood group antigens and immune responses-detailed knowledge is necessary to prevent immunization and to follow up immunized individuals
    ISBT Science Series 2010
  • Maria Therese Ahlen, Anne Husebekk, Mette Kjær Killie, Bjørn Ragnar Skogen, Tor Brynjar Stuge :
    T-cell responses associated with neonatal alloimmune thrombocytopenia: isolation of HPA-1a-specific, HLA-DRB3*0101-restricted CD4+ T cells
    Blood 2009 DOI
  • Ingvild Hausberg Sørvoll, Ingvild Jenssen Lægreid, Tom Sollid, Maria Therese Ahlen, Silje Johansen, Håkon Reikvam :
    Low Incidence of Anti-PF4/Heparin Antibodies in Patients with Acute Myelogenous Leukemia
    Mediterranean Journal of Hematology and Infectious Diseases (MJHID) 2024 DOI
  • Heidi Tiller, Nora Hersoug Nedberg, Mona Nystad, Maria Therese Ahlen, eirin listau Bertelsen, Anne Husebekk et al.:
    New insights on maternal platelet alloimmunization and placenta function
    2023
  • Adam J. Kanack, Ingvild Jenssen Lægreid, Silje Johansen, Håkon Reikvam, Maria Therese Ahlen, Anand Padmanabhan :
    Human papilloma virus vaccine and VITT antibody induction
    American Journal of Hematology 2022 DOI
  • Maria Therese Ahlen :
    Fighting anti-CD36–mediated FNAIT
    Blood 2021 DOI
  • Philip Y. Choi, Rachael F. Grace, Maria Therese Ahlen, Ishac Nazy, Ulrich J. Sachs, Donald M. Arnold et al.:
    The SSC platelet immunology register of VITT and VIITP: Toward standardization of laboratory and clinical parameters
    Journal of Thrombosis and Haemostasis 2021 DOI
  • Heidi Tiller, Mette Kjær, Maria Therese Ahlen, Jens Kjeldsen-Kragh :
    Føtal/neonatal alloimmun trombocytopeni (FNAIT) - hvordan redusere risiko for intrakraniell blødning hos foster/ nyfødt - erfaringer fra Norge
    Bestpractice Onkologi/Hematologi 2019
  • Ida Løken Killie, Maria Therese Ahlen, Anne Husebekk, Bjørn Ragnar Skogen, Tor Brynjar Stuge :
    Induction and detection of in vivo immune responses to HPA-1a in a novel murine model of fetal/neonatal alloimmune thrombocytopenia (FNAIT)
    2014
  • Gøril Heide, Tor Brynjar Stuge, Bjørn Ragnar Skogen, Anne Husebekk, Maria Therese Ahlen :
    The DR7-DQ2 Haplotype in a Native Norwegian Population
    Scandinavian Journal of Immunology 2013 DOI
  • Ida Løken Killie, Anne Husebekk, Maria Therese Ahlen, M. Roalso, Bjørn Ragnar Skogen, Tor Brynjar Stuge :
    ARE CURRENT MURINE MODELS OF FETAL/NEONATAL ALLOIMMUNE THROMBOCYTOPENIA BRINGING US CLOSER TO A BETTER UNDERSTANDING OF PATHOPHYSIOLOGY AND TREATMENT OF THE DISEASE?
    Vox Sanguinis 2013
  • Anne Husebekk, Heidi Tiller, Mette Kjær Killie, Mariana Eksteen, Maria Therese Ahlen, Tor Brynjar Stuge et al.:
    TOWARDS A PROPHYLACTIC TREATMENT OF HPA-1A-RELATED FETAL AND NEONATAL ALLOIMMUNE THROMBOCYTOPENIA (FNAIT)
    Vox Sanguinis 2012
  • Anne Husebekk, Maria Therese Ahlen, Mette Kjær Killie, Heidi Tiller, Mariana Eksteen, Ida Løken Killie et al.:
    MATERNAL ALLOIMMUNE RESPONSE DURING PREGNANCY: BRAKE OF MATERNAL TOLERANCE TO FETAL HUMAN PLATELET ANTIGEN 1A ANTIGEN MAY BE ASSOCIATED WITH REDUCED PLACENTAL FUNCTION
    Placenta 2011
  • Maria Therese Ahlen, Mette Kjær Killie, Bjørn Ragnar Skogen, Anne Husebekk, Tor Brynjar Stuge :
    Isolation and Characterization of CD4+ T Cells Specific for the HPA 1a Epitope Associated with Neonatal Alloimmune Thrombocytopenia
    Blood 2007
  • Maria Therese Ahlen, Mette Kjær Killie, Anne Husebekk, Jens Kjeldsen-Kragh, ML Olsson, Bjørn Ragnar Skogen :
    The Development of Severe Anti-HPA 1a-Related Neonatal Alloimmune Thrombocytopenia Is Influenced by the Maternal ABO Type
    Blood 2007

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    Research interests

    Platlet immunology
    Alloimmune repsonses in pregnancy
    T cell responses associated with Fetal/neonatal alloimmune thrombocytopenia

    Publications

     

    2025
    Improving prediction of fetal/neonatal intracranial hemorrhage in HPA-1a alloimmunized pregnancies to guide antenatal management: An observational cohort study. Ernstsen SL, Ahlen MT, Bertelsen EL, Kjeldsen-Kragh J, Husebekk A, Tiller H. Acta Obstet Gynecol Scand. 2025 Oct;104(10):1859-1868. doi: 10.1111/aogs.70031. Epub 2025 Aug 20. Original Research article.

    Adding contrast to shed some light - A case of acute thrombocytopenia due to iohexol-dependent antibodies to glycoprotein IIb/IIIa. Lægreid IJ, Hald EM, Arsenovic MG, Ernstsen SL, Asplund Högelin K, Mørtberg TV, Ahlen MT. J Thromb Haemost. 2025 Oct 9:S1538-7836(25)00607-5. doi: 10.1016/j.jtha.2025.09.016. Online ahead of print. Original Research article.

    Safety and Efficacy of Daratumumab in Immune Thrombocytopenia. Tsykunova G, Holme PA, Tran HTT Dr, Frederiksen H, Tjonnfjord E, Munthe LA, Drivet E, Kared H, Sørvoll IH, Ahlen MT, Mahevas M, Michel M, Bussel JB, Kuter DJ, Tvedt THA, Ghanima W. Blood Adv. 2025 Online ahead of print. doi: 10.1182/bloodadvances.2025017279. Original Research article.

    Rising to the challenge: an international Delphi consensus study on fetal and neonatal alloimmune thrombocytopenia. Pothof R, van den Akker-van Marle EM, de Vos TW, Tiller H, Bussel JB, Ahlén MT, Curtis BR, Lopriore E, Verweij EJTJ, de Haas M; FNAIT modified Delphi expert group. Lancet Haematol. 2025 Apr;12(4):e304-e311. doi: 10.1016/S2352-3026(25)00029-8. Review

    2024
    Placenta-associated biomarkers and pregnancy outcome in HPA-1a alloimmunization: A prospective cohort study. Nedberg NH, Nystad M, Ahlen MT, Bertelsen EL, Guz K, Uhrynowska M, Dębska M, Gierszon A, Orzińska A, Husebekk A, Brojer E, Staff AC, Tiller H. Placenta. 2024. Dec;158:185-191. doi: 10.1016/j.placenta.2024.10.014. Original Research article.

    Low Incidence of Anti-PF4/Heparin Antibodies in Patients with Acute Myelogenous Leukemia. Sørvoll IH, Lægreid IJ, Sollid T, Ahlen MT, Johansen S, Reikvam H. Mediterr J Hematol Infect Dis. 2024 Jul 1;16(1):e2024057. doi: 10.4084/MJHID.2024.057. Original Research article.

    2023
    Coucheron T, Uhrynowska M, Guz K, Orzińska A, Debska M, Gierszon A, Ahlen MT, Bertelsen EL, Berge G, Husebekk A, Brojer E, Tiller H. What's with the boys? Lower birth weight in boys from HPA-1a alloimmunized pregnancies - New insights from a large prospective screening study in Poland. J Reprod Immunol. 2023. 160:104168. doi: 10.1016/j.jri.2023.104168. Original Research article.

    Ahlen MT, Bussel JB. Desialylation unmasks HPA-9B alloantibodies. Blood. 2023. 142(22):1853-1854. doi: 10.1182/blood.2023022495. Commentary.

     Garabet L, Eriksson A, Tjønnfjord E, Cui XY, Olsen MK, Jacobsen HK, Jørgensen CT, Mathisen ÅB, Mowinckel MC, Ahlen MT, Sørvoll IH, Horvei KD, Ernstsen SL, Lægreid IJ, Stavik B, Holst R, Sandset PM, Ghanima W. SARS-CoV-2 vaccines are not associated with hypercoagulability in apparently healthy people. Res Pract Thromb Haemost. 2023 Jan;7(1):100002. doi: 10.1016/j.rpth.2022.100002 Original Research article.

    Schultz NH, Søraas AVL, Sørvoll IH, Akkök ÇA, Vetlesen A, Bhamra JS, Ahlen MT, Holme PA, Aamodt AH, Skagen K, Skattør TH, Skjelland M, Wiedmann MK. Vaccine associated benign headache and cutaneous hemorrhage after ChAdOx1 nCoV-19 vaccine: A cohort study. J Stroke Cerebrovasc Dis. 2023 Jan;32(1):106860. doi: 10.1016/j.jstrokecerebrovasdis.2022.106860. Epub 2022 Nov 17. Original Research article.

    2022
    Ernstsen SL, Ahlen MT, Johansen T, Bertelsen EL, Kjeldsen-Kragh J, Tiller H. Antenatal intravenous immunoglobulins in pregnancies at risk of fetal and neonatal alloimmune thrombocytopenia: comparison of neonatal outcome in treated and nontreated pregnancies. Am J Obstet Gynecol. 2022; S0002-9378(22)00325-8. Original Research article.

    Kanack AJ, Laegreid IJ, Johansen S, Reikvam H, Ahlen MT, Padmanabhan A. Human papilloma virus vaccine and VITT antibody induction. Am J Hematol. 2022 Oct;97(10):E363-E364. doi: 10.1002/ajh.26659. Epub 2022 Aug 3.

    Laegreid IJ, Olsen MI, Harr JI, Grønli RH, Mørtberg TV, Ernstsen SL, Ahlen MT. Acute drug-induced immune thrombocytopenia - A work of articaine. Transfusion. 2022 May;62(5):1142-1147. doi: 10.1111/trf.16858. Epub 2022 Mar 19.

    Ueland T, Hausberg I, Mørtberg TV, Dahl TB, Lerum TV, Michelsen A, Ranheim T, Nezvalova Henriksen K, Dyrhol-Riise AM, Holme PA, Aaløkken TM, Skjønsberg OH, Barratt-Due A, Ahlén MT, Aukrust P, Halvorsen B. Anti-PF4/polyanion antibodies in COVID-19 patients are associated with disease severity and pulmonary pathology. Platelets. 2022 May 19;33(4):640-644. Original Research article.

    Mørtberg TV, Zhi H, Vidarsson G, Foss S, Lissenberg-Thunnissen S, Wuhrer M, Michaelsen TE, Skogen B, Stuge TB, Andersen JT, Newman PJ, Ahlen MT. Prevention of Fetal/Neonatal Alloimmune Thrombocytopenia in Mice: Biochemical and Cell Biological Characterization of Isoforms of a Human Monoclonal Antibody. ImmunoHorizons. 2022; 6 (1) 90-103; Original Research article.

    Johansen S, Laegreid IJ, Ernstsen SL, Azrakhsh NA, Kittang AO, Lindås R, Gjertsen BT, Vetti N, Mørtberg TV, Sørvoll IH, Holme PA, Ahlen MT, Reikvam H. Thrombosis and thrombocytopenia after HPV vaccination. J Thromb Haemost. 2022 Mar;20(3):700-704. doi: 10.1111/jth.15604. Epub 2021

    2021
    Ahlen MT. Fighting anti-CD36-mediated FNAIT. Blood. 2021 Nov 4;138(18):1650-1652. doi: 10.1182/blood.2021012454. Commentary.

    Schultz NH, Sørvoll IH, Michelsen AE, Munthe LA, Lund-Johansen F, Ahlen MT, Wiedmann M, Aamodt AH, Skattør TH, Tjønnfjord GE, Holme PA Thrombosis and Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination. N Engl J Med. 2021; 384(22):2124-2130. Brief report.

    Newly discovered catastrophic antibody formation after the AstraZeneca vaccine. Lægreid IJ, Sørvoll IH, Ernstsen SL, Horvei KD, Hauglann S, Lund S, Grønli RH, Solbø C, Pedersen M, Ahlen MT. Tidsskr Nor Laegeforen. 2021 Apr 10;141. doi: 10.4045/tidsskr.21.0265.

    Sørvoll IH, Horvei KD, Ernstsen SL, Laegreid IJ, Lund S, Grønli RH, Olsen MK, Jacobsen HK, Eriksson A, Halstensen AM, Tjønnfjord E, Ghanima W, Ahlen MT. An observational study to identify the prevalence of thrombocytopenia and anti-PF4/polyanion antibodies in Norwegian health care workers after COVID-19 vaccination. J Thromb Haemost. 2021; (7):1813-1818. Original Research article.

    Zhi H, Ahlen MT, Skogen B, Newman DK, Newman PJ. Preclinical evaluation of immunotherapeutic regimens for fetal/neonatal alloimmune thrombocytopenia. Blood Adv. 2021; 5(18):3552-3562. Original Research article.

    Nazy I, Sachs UJ, Arnold DM, McKenzie SE, Choi P, Althaus K, Ahlen MT, Sharma R, Grace RF, Bakchoul T. Recommendations for the clinical and laboratory diagnosis of VITT against COVID-19: Communication from the ISTH SSC Subcommittee on Platelet Immunology. J Thromb Haemost. 2021 Jun;19(6):1585-1588.

    2020
    Ahlen MT, Heide G, Husebekk A, Skogen B, Kjeldsen‐Kragh J, Stuge TB. The prevalence of HPA‐1a alloimmunization and the potential risk of FNAIT depend on both the DRB3*01:01 allele and associated DR‐DQ haplotypes. Scand J Immunol. 2020; 92:e12890. Original Research article.

    Kjeldsen-Kragh J, Ahlen MT. Foetal and neonatal alloimmune thrombocytopenia - The role of the HLA-DRB3*01:01 allele for HPA-1a-immunisation and foetal/neonatal outcome. Transfus Apher Sci. 2020 Feb;59(1):102707. Review.

    Rasmussen TV, Ahlen MT. Murine models for studying treatment, prevention and pathogenesis of FNAIT. Transfus Apher Sci. 2020 Feb;59(1):102706. Review.

    Tiller H, Ahlen MT, Akkök ÇA, Husebekk A. Fetal and neonatal alloimmune thrombocytopenia - The Norwegian management model. Transfus Apher Sci. 2020 Feb;59(1):102711

    2018
    Zhi H, Ahlen MT, Thinn, AM, Weiler, H, Curtis, BR., Skogen, B, Zhu, J, Newman, PJ. High-resolution mapping of the polyclonal immune response to the human platelet alloantigen HPA-1a (PlA1). Blood Advances, 2018: 2(21), 3001-3011. Original Research article.

    Orzińska A, Guz K, Uhrynowska M, Dębska M, Mikula M, Ostrowski J, Ahlen MT, Husebekk A, Brojer E. Noninvasive prenatal HPA-1 typing in HPA-1a negative pregnancies selected in the Polish PREVFNAIT screening program. Transfusion. 2018 Nov;58(11):2705-2711.

    2017
    Tiller H, Husebekk A, Ahlen MT, Stuge TB, Skogen B. Current perspectives on fetal and neonatal alloimmune thrombocytopenia - increasing clinical concerns and new treatment opportunities. Int J Womens Health. 2017 Apr 19;9:223-234. Review.

    Unraveling the role of maternal anti-HLA class I antibodies in fetal and neonatal thrombocytopenia-Antibody specificity analysis using epitope data. Dahl J, Refsum E, Ahlen MT, Egeland T, Jensen T, Viken MK, Stuge TB, Acharya G, Husebekk A, Skogen B, Tiller H. J Reprod Immunol. 2017 Aug;122:1-9. doi: 10.1016/j.jri.2017.06.003. Original Research article.

    2016
    Ahlen MT, Husebekk A, Killie IL, Skogen B, Stuge TB. T cell responses to Human Platelet Antigen-1a involve a unique form of indirect allorecognition. JCI Insight. 2016;1(14):e86558 Original research article.

    Older
    The DR7-DQ2 haplotype in a native Norwegian population. Heide G, Stuge TB, Skogen B, Husebekk A, Ahlen MT. Scand J Immunol. 2013 May;77(5):429-30. doi: 10.1111/sji.12031. Original research article.

    Foetal/neonatal alloimmune thrombocytopenia in Egypt; human platelet antigen genotype frequencies and antibody detection and follow-up in pregnancies. Husebekk A, El Ekiaby M, Gorgy G, Killie MK, Uhlin-Hansen C, Salma W, Navarrete C, El Afandi M, Skogen B, Ahlen MT. Transfus Apher Sci. 2012 Dec;47(3):277-82. doi: 10.1016/j.transci.2012.04.001.

    The development of severe neonatal alloimmune thrombocytopenia due to anti-HPA-1a antibodies is correlated to maternal ABO genotypes. Ahlen MT, Husebekk A, Killie MK, Kjeldsen-Kragh J, Olsson ML, Skogen B. Clin Dev Immunol. 2012;2012:156867. doi: 10.1155/2012/156867. Original research article.

    Ahlen MT, Husebekk A, Killie MK, Skogen B and Stuge TB. T-cell responses associated with neonatal alloimmune thrombocytopenia: isolation of HPA-1a-specific, HLA-DRB3*0101-restricted CD4+ T cells. Blood. 2009 Apr 16;113(16):3838-44. Original research article.

    ORCID: https://orcid.org/0000-0002-3104-3818

    Member of research group

    Immunology research group   English content

    Member of project

    Prophylaxis to prevent alloimmunization and FNAIT Cellular responses in FNAIT Blood Brain Barrier in FNAIT