Photo: Bjørn-Kåre Iversen
John Bjarne Hansen
Job description
Head of K. G. Jebsen Thrombosis Research and Experice Center
Senior consultant in Hematology, University Hospital of North Norway
Samantha Swamy,
Thor Ueland,
John Bjarne Hansen,
Omri Snir,
Sigrid Kufaas Brækkan
:
Plasma levels of P-selectin and future risk of incident venous thromboembolism
Maria A. de Winter,
Alicia Uijl,
Harry R. Büller,
Marc Carrier,
Alexander T. Cohen,
John Bjarne Hansen
et al.:
Redefining clinical venous thromboembolism phenotypes: a novel approach using latent class analysis
Journal of Thrombosis and Haemostasis 2023 DOI
Oda Leknessund,
Vania Maris Morelli,
John Bjarne Hansen,
Sigrid Kufaas Brækkan
:
Hand grip strength in venous thromboembolism: risk of recurrence and mortality
Safak Caglayan,
John Bjarne Hansen,
Omri Snir
:
Optimized workflow to modify microRNA expression in primary human intravascular cells
Monique J.T. Crobach,
Rayna J.S. Anijs,
Sigrid Kufaas Brækkan,
Marianne T. Severinsen,
Jens Hammerstrøm,
Hanne Skille
et al.:
Survival after cancer-related venous thrombosis: the Scandinavian Thrombosis and Cancer Study
Maria A. De Winter,
Harry R. Büller,
Marc Carrier,
Alexander T. Cohen,
John Bjarne Hansen,
Karin A. H. Kaasjager
et al.:
Recurrent venous thromboembolism and bleeding with extended anticoagulation: the VTE-PREDICT risk score
European Heart Journal 2023 DOI
Vårin Eiriksdatter Wikan,
Birgitte Gladsø Tøndel,
Vania Maris Morelli,
Ellen Elisabeth Brodin,
Sigrid Kufaas Brækkan,
John Bjarne Hansen
:
Diagnostic Blood Biomarkers for Acute Pulmonary Embolism: A Systematic Review
Diagnostics (Basel) 2023 DOI
Steven P. Grover,
Tomohiro Kawano,
Jun Wan,
Pansakorn Tanratana,
Zsofia Polai,
Young J. Shim
et al.:
C1 inhibitor deficiency enhances contact pathway–mediated activation of coagulation and venous thrombosis
Blood 2023 DOI
Magnus Edvardsen,
Ellen-Sofie Hansen,
Thor Ueland,
Pål Aukrust,
Sigrid Kufaas Brækkan,
Vania Maris Morelli
et al.:
Impact of the von Willebrand factor-ADAMTS-13 axis on the risk of future venous thromboembolism
Journal of Thrombosis and Haemostasis 2023 DOI
Espen Waage Skjeflo,
Line Holtet Evensen,
Søren Beck Jensen,
Nadezhda Latysheva,
Annika Elisabet Michelsen,
Thor Ueland
et al.:
Complement factors B, D, C3bBbP and risk of future venous thromboembolism
Clinical Immunology 2023 DOI
Steven P. Grover,
Omri Snir,
Kristian Dalsbø Hindberg,
Tatianna M. Englebert,
Sigrid Kufaas Brækkan,
Vania Maris Morelli
et al.:
High plasma levels of C1-inhibitor are associated with lower risk of future venous thromboembolism
Fridtjof Balteskard Rinde,
Camilla Tøvik Jørgensen,
Heidi Hassel Pettersen,
John Bjarne Hansen,
Waleed Ghanima,
Sigrid Kufaas Brækkan
:
Low D-dimer levels at diagnosis of venous thromboembolism are associated with reduced risk of recurrence: data from the TROLL registry
Sigrid Kufaas Brækkan,
John Bjarne Hansen
:
VTE epidemiology and challenges for VTE prevention at the population level: VTE epidemiology
Dana Meknas,
Sigrid Kufaas Brækkan,
John Bjarne Hansen,
Vania Maris Morelli
:
Surgery As a Trigger for Incident Venous Thromboembolism: Results from a Population-Based Case-Crossover Study
TH Open 2023 DOI
Helle Jørgensen,
Erzsébet Horváth-Puhó,
Kristina Laugesen,
Sigrid Kufaas Brækkan,
John Bjarne Hansen,
Henrik Toft Sørensen
:
The Interaction Between Venous Thromboembolism and Socioeconomic Status on the Risk of Disability Pension
Tobias Frischmuth,
Kristian Hindberg,
Pål Aukrust,
Thor Ueland,
Sigrid Kufaas Brækkan,
John Bjarne Hansen
et al.:
Elevated plasma levels of plasminogen activator inhibitor-1 are associated with risk of future incident venous thromboembolism
Birgitte Gladsø Tøndel,
Vania Maris Morelli,
John Bjarne Hansen,
Sigrid Kufaas Brækkan
:
Risk factors and predictors for venous thromboembolism in people with ischemic stroke: A systematic review
Omri Snir,
line Wilsgård,
Nadezhda Latysheva,
Casper Ullsten-Wahlund,
Sigrid Kufaas Brækkan,
Kristian Dalsbø Hindberg
et al.:
Plasma levels of platelet-derived microvesicles are associated with risk of future venous thromboembolism
Lisa Jakobsen,
Tobias Frischmuth,
Sigrid Kufaas Brækkan,
John Bjarne Hansen,
Vania Maris Morelli
:
Joint Effect of Multiple Prothrombotic Genotypes and Mean Platelet Volume on the Risk of Incident Venous Thromboembolism
Paul L. den Exter,
Scott C. Woller,
Helia Robert-Ebadi,
Camila Masias,
Pierre-Emmanuel Morange,
David Castelli
et al.:
Management of bleeding risk in patients who receive anticoagulant therapy for venous thromboembolism: Communication from the ISTH SSC Subcommittee on Predictive and Diagnostic Variables in Thrombotic Disease
Carolina E. Touw,
Banne Nemeth,
Willem M. Lijfering,
Raymond A. van Adrichem,
line Wilsgård,
Nadezhda Latysheva
et al.:
Effect of lower-leg trauma and knee arthroscopy on procoagulant phospholipid-dependent activity
Aniket Mishra,
Rainer Malik,
Tsuyoshi Hachiya,
Tuuli Jürgenson,
Shinichi Namba,
Daniel C. Posner
et al.:
Stroke genetics informs drug discovery and risk prediction across ancestries
Christabel Esi Damoah,
Omri Snir,
Kristian Dalsbø Hindberg,
Peter Garred,
Judith K Ludviksen,
Sigrid Kufaas Brækkan
et al.:
High Levels of Complement Activating Enzyme MASP-2 Are Associated With the Risk of Future Incident Venous Thromboembolism
Elias Allarai,
Wei-Hsuan Lee,
Stephen Burgess,
Susanna C. Larsson,
Sara Lindstrom,
Lu Wang
et al.:
Genetically predicted cortisol levels and risk of venous thromboembolism
Scott C. Woller,
Kerstin de Wit,
Helia Robert-Ebadi,
Camila Masias,
Frederikus A. Klok,
Paul L. den Exter
et al.:
A systematic review of biomarkers among hospitalized patients with COVID-19 predictive of venous thromboembolism: A communication from the Predictive and Diagnostic Variables Scientific and Standardization Committee of the ISTH
Oda Leknessund,
Vania Maris Morelli,
Bjørn Heine Strand,
John Bjarne Hansen,
Sigrid Kufaas Brækkan
:
Hand grip strength and risk of incident venous thromboembolism: The Tromsø study
Line Holtet Evensen,
Carl-Arne Arnesen,
Frits Richard Rosendaal,
Maiken Elvestad Gabrielsen,
Ben Michael Brumpton,
Kristian Hveem
et al.:
The Risk of Venous Thromboembolism Attributed to Established Prothrombotic Genotypes
Joakim Knutsen Sejrup,
Birgitte Gladsø Tøndel,
Vania Maris Morelli,
Maja-Lisa Løchen,
Inger Njølstad,
Ellisiv B. Mathiesen
et al.:
Joint effect of myocardial infarction and obesity on the risk of venous thromboembolism: The Tromsø Study
Helle Jørgensen,
Erzsebet Horvath-Puho,
Kristina Laugesen,
Sigrid Kufaas Brækkan,
John Bjarne Hansen,
Henrik Toft Sørensen
:
Venous thromboembolism and risk of depression: a population-based cohort study
Florian Thibord,
Derek Klarin,
Jennifer A. Brody,
Ming-Huei Chen,
Michael G. Levin,
Daniel I. Chasman
et al.:
Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors
Helle Jørgensen,
Erzsebet Horvath-Puho,
Kristina Laugesen,
Sigrid Kufaas Brækkan,
John Bjarne Hansen,
Henrik Toft Sørensen
:
Socioeconomic status and risk of incident venous thromboembolism
Journal of Thrombosis and Haemostasis 2021 DOI
Espen Waage Skjeflo,
Sigrid Kufaas Brækkan,
Judith K Ludviksen,
Omri Snir,
Kristian Hindberg,
Tom Eirik Mollnes
et al.:
Elevated plasma concentration of complement factor C5 is associated with risk of future venous thromboembolism
Magnus Edvardsen,
Ellen-Sofie Hansen,
Kristian Hindberg,
Vania Maris Morelli,
Thor Ueland,
Pål Aukrust
et al.:
Combined effects of plasma von Willebrand factor and platelet measures on the risk of incident venous thromboembolism
Bjarne Østerud,
Nadezhda Latysheva,
Christian Schoergenhofer,
Bernd Jilma,
John-Bjarne Hansen,
Omri Snir
:
A rapid, sensitive, and specific assay to measure TF activity based on chromogenic determination of thrombin generation
Tobias Frischmuth,
Kristian Hindberg,
Pål Aukrust,
Thor Ueland,
Sigrid K. Brækkan,
John-Bjarne Hansen
et al.:
Plasma levels of leptin and risk of future incident venous thromboembolism
Magnus Edvardsen,
Kristian Hindberg,
Ellen-Sofie Hansen,
Vania Maris Morelli,
Thor Ueland,
Pål Aukrust
et al.:
Plasma levels of von Willebrand factor and future risk of incident venous thromboembolism
Hanne Skille,
Benedikte Paulsen,
Kristian Hveem,
Marianne T. Severinsen,
Maiken Elvestad Gabrielsen,
Søren R. Kristensen
et al.:
Prothrombotic genotypes and risk of venous thromboembolism in occult cancer
Gro Grimnes,
Soerajja Bhoelan,
Kristian Hindberg,
Mark Davids,
Max Nieuwdorp,
Tom E. Mollnes
et al.:
Impact of a Vancomycin-Induced Shift of the Gut Microbiome in a Gram-Negative Direction on Plasma Factor VIII:C Levels: Results from a Randomized Controlled Trial
Benedikte Paulsen,
Olga Vikhammer Gran,
Marianne T. Severinsen,
Jens Hammerstrøm,
Søren Risom Kristensen,
Suzanne C. Cannegieter
et al.:
Association of smoking and cancer with the risk of venous thromboembolism: the Scandinavian Thrombosis and Cancer cohort
Helle Jørgensen,
Erzsébet Horváth-Puhó,
Kristina Laugesen,
Sigrid Kufaas Brækkan,
John-Bjarne Hansen,
Henrik Toft Sørensen
:
Risk of a permanent work-related disability pension after incident venous thromboembolism in Denmark: A population-based cohort study
Carl Arne Løchen Arnesen,
Katalin Veres,
Erzsébet Horváth-Puhó,
John-Bjarne Hansen,
Henrik Toft Sørensen,
Sigrid K. Brækkan
:
Estimated lifetime risk of venous thromboembolism in men and women in a Danish nationwide cohort: impact of competing risk of death
Ellen-Sofie Hansen,
Fridtjof Balteskard Rinde,
Magnus Edvardsen,
Kristian Hindberg,
Nadezhda Latysheva,
Pål Aukrust
et al.:
Elevated plasma D-dimer levels are associated with risk of future incident venous thromboembolism
Grégoire Le Gal,
Marc Carrier,
Lana A. Castellucci,
Adam Cuker,
John-Bjarne Hansen,
Frederikus A. Klok
et al.:
Development and implementation of common data elements for venous thromboembolism research: on behalf of SSC Subcommittee on official Communication from the SSC of the ISTH
Journal of Thrombosis and Haemostasis 2021 DOI
Line Holtet Evensen,
Aaron R. Folsom,
James S. Pankow,
John-Bjarne Hansen,
Matthew Allison,
Mary Cushman
et al.:
Hemostatic factors, inflammatory markers, and risk of incident venous thromboembolism: The Multi-Ethnic Study of Atherosclerosis
Cathrine Ramberg,
Kristian Hindberg,
Joseph S. Biedermann,
Suzanne C. Cannegieter,
Felix J. van der Meer,
Omri Snir
et al.:
Rosuvastatin treatment decreases plasma procoagulant phospholipid activity after a VTE: A randomized controlled trial
Cathrine Ramberg,
Line Wilsgård,
Nadezhda Latysheva,
Sigrid Kufaas Brækkan,
Kristian Hindberg,
Timofey Sovershaev
et al.:
Plasma procoagulant phospholipid clotting time and venous thromboembolism risk
Tobias Frischmuth,
Kristian Hindberg,
Maiken Elvestad Gabrielsen,
Ben Michael Brumpton,
Kristian Hveem,
Sigrid Kufaas Brækkan
et al.:
Joint Effect of Multiple Prothrombotic Genotypes and Obesity on the Risk of Incident Venous Thromboembolism
Helle Jørgensen,
Erzsébet Horváth-Puhó,
Kristina Laugesen,
Sigrid Brækkan,
John-Bjarne Hansen,
Henrik Toft Sørensen
:
Socioeconomic status and risk of incident venous thromboembolism
Bjarne Østerud,
Nadezhda Latysheva,
John Bjarne Hansen,
Omri Snir
:
“A rapid, sensitive, and specific assay to measure tissue factor activity based on chromogenic determination of thrombin generation”: reply
Journal of Thrombosis and Haemostasis 2023 DOI
Casper Ullsten-Wahlund,
Safak Caglayan,
Christabel Esi Damoah,
John Bjarne Hansen,
Omri Snir
:
Hypoxia augments proinflammatory activation of endothelial cells towards a prothrombotic phenotype
2021
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Research interests
Risk factors of venous thromboembolism
Pathophysiology of venous thromboembolism
Role of monocytes/macrophages in thrombogenesis
Role of microparticles in thrombogenesis
Member of research group
CV
Academic degree
1989 Cand.med (MD), University of Tromsø
1997 Dr. med (PhD in cardiovascular medicine) University of Tromsø
Previous academic positions
1991-94 Research fellow, Univ. of Tromsø (Norw. Council on cardiovascular diseases)
1994-95 Post.doc., University of Tromsø
1996-2005 Associate professor in medicine, University of Tromsø (20-50% position)
2006-2008 Professor I in Hematology, University of Tromsø (100% position)
2007-2008 Vice Dean for Research, Faculty of Health Sciences, University of Tromsø
2008-2009 Visiting professor, The Scripps Research Institute, La Jolla, CA, USA
Publications
208 original full papers in peer-reviewed journals listed in PubMed and 22 review articles and book chapters- Contributed to more than 320 abstracts presented at and published in conjunction with scientific international meetings/conferences.
Supervision of PhD-students
Main supervisor for 24 completed PhD-thesis. Present supervision of 13 PhD-students as main supervisor and mentor for 5 postdoctors