Bilde av Hansen, John Bjarne
Photo: Bjørn-Kåre Iversen
Bilde av Hansen, John Bjarne
Department of Clinical Medicine john-bjarne.hansen@uit.no +4777625105 41472374 Tromsø FARM F4.210A

Hansen, John Bjarne


Job description

Head of K. G. Jebsen Thrombosis Research and Experice Center

Senior consultant in Hematology, University Hospital of North Norway


  • Espen Waage Skjeflo, Line Holtet Evensen, Søren Beck Jensen, Nadezhda Latysheva, Annika Elisabet Michelsen, Thor Ueland et al.:
    Complement factors B, D, C3bBbP and risk of future venous thromboembolism
    Clinical Immunology 2023 DOI
  • Safak Caglayan, John Bjarne Hansen, Omri Snir :
    Optimized workflow to modify microRNA expression in primary human intravascular cells
    BMC Immunology 2023 DOI
  • Steven P. Grover, Omri Snir, Kristian Dalsbø Hindberg, Tatianna M. Englebert, Sigrid Kufaas Brækkan, Vania Maris Morelli et al.:
    High plasma levels of C1-inhibitor are associated with lower risk of future venous thromboembolism
    Journal of Thrombosis and Haemostasis 2023 DOI
  • Fridtjof Balteskard Rinde, Camilla Tøvik Jørgensen, Heidi Hassel Pettersen, John Bjarne Hansen, Waleed Ghanima, Sigrid Kufaas Brækkan :
    Low D-dimer levels at diagnosis of venous thromboembolism are associated with reduced risk of recurrence: data from the TROLL registry
    Journal of Thrombosis and Haemostasis 2023 ARKIV / DOI
  • Helle Jørgensen, Erzsébet Horváth-Puhó, Kristina Laugesen, Sigrid Kufaas Brækkan, John Bjarne Hansen, Henrik Toft Sørensen :
    The Interaction Between Venous Thromboembolism and Socioeconomic Status on the Risk of Disability Pension
    Clinical Epidemiology 2022 ARKIV / DOI
  • Tobias Frischmuth, Kristian Hindberg, Pål Aukrust, Thor Ueland, Sigrid Kufaas Brækkan, John Bjarne Hansen et al.:
    Elevated plasma levels of plasminogen activator inhibitor-1 are associated with risk of future incident venous thromboembolism
    Journal of Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Birgitte Gladsø Tøndel, Vania Maris Morelli, John Bjarne Hansen, Sigrid Kufaas Brækkan :
    Risk factors and predictors for venous thromboembolism in people with ischemic stroke: A systematic review
    Journal of Thrombosis and Haemostasis 11. July 2022 ARKIV / DOI
  • Omri Snir, line Wilsgård, Nadezhda Latysheva, Casper Ullsten-Wahlund, Sigrid Kufaas Brækkan, Kristian Dalsbø Hindberg et al.:
    Plasma levels of platelet-derived microvesicles are associated with risk of future venous thromboembolism
    Journal of Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Lisa Jakobsen, Tobias Frischmuth, Sigrid Kufaas Brækkan, John Bjarne Hansen, Vania Maris Morelli :
    Joint Effect of Multiple Prothrombotic Genotypes and Mean Platelet Volume on the Risk of Incident Venous Thromboembolism
    Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Paul L. den Exter, Scott C. Woller, Helia Robert-Ebadi, Camila Masias, Pierre-Emmanuel Morange, David Castelli et al.:
    Management of bleeding risk in patients who receive anticoagulant therapy for venous thromboembolism: Communication from the ISTH SSC Subcommittee on Predictive and Diagnostic Variables in Thrombotic Disease
    Journal of Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Carolina E. Touw, Banne Nemeth, Willem M. Lijfering, Raymond A. van Adrichem, line Wilsgård, Nadezhda Latysheva et al.:
    Effect of lower-leg trauma and knee arthroscopy on procoagulant phospholipid-dependent activity
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2022 ARKIV / DOI
  • Aniket Mishra, Rainer Malik, Tsuyoshi Hachiya, Tuuli Jürgenson, Shinichi Namba, Daniel C. Posner et al.:
    Stroke genetics informs drug discovery and risk prediction across ancestries
    Nature 2022 ARKIV / DOI
  • Christabel Esi Damoah, Omri Snir, Kristian Dalsbø Hindberg, Peter Garred, Judith K Ludviksen, Sigrid Kufaas Brækkan et al.:
    High Levels of Complement Activating Enzyme MASP-2 Are Associated With the Risk of Future Incident Venous Thromboembolism
    Arteriosclerosis, Thrombosis and Vascular Biology 2022 ARKIV / DOI
  • Elias Allarai, Wei-Hsuan Lee, Stephen Burgess, Susanna C. Larsson, Sara Lindstrom, Lu Wang et al.:
    Genetically predicted cortisol levels and risk of venous thromboembolism
    PLOS ONE 2022 ARKIV / DOI
  • Scott C. Woller, Kerstin de Wit, Helia Robert-Ebadi, Camila Masias, Frederikus A. Klok, Paul L. den Exter et al.:
    A systematic review of biomarkers among hospitalized patients with COVID-19 predictive of venous thromboembolism: A communication from the Predictive and Diagnostic Variables Scientific and Standardization Committee of the ISTH
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2022 ARKIV / DOI
  • Oda Leknessund, Vania Maris Morelli, Bjørn Heine Strand, John Bjarne Hansen, Sigrid Kufaas Brækkan :
    Hand grip strength and risk of incident venous thromboembolism: The Tromsø study
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2022 FULLTEKST / ARKIV / DOI
  • Line Holtet Evensen, Carl-Arne Arnesen, Frits Richard Rosendaal, Maiken Elvestad Gabrielsen, Ben Michael Brumpton, Kristian Hveem et al.:
    The Risk of Venous Thromboembolism Attributed to Established Prothrombotic Genotypes
    Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Joakim Knutsen Sejrup, Birgitte Gladsø Tøndel, Vania Maris Morelli, Maja-Lisa Løchen, Inger Njølstad, Ellisiv B. Mathiesen et al.:
    Joint effect of myocardial infarction and obesity on the risk of venous thromboembolism: The Tromsø Study
    Journal of Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Helle Jørgensen, Erzsebet Horvath-Puho, Kristina Laugesen, Sigrid Kufaas Brækkan, John Bjarne Hansen, Henrik Toft Sørensen :
    Venous thromboembolism and risk of depression: a population-based cohort study
    Journal of Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Florian Thibord, Derek Klarin, Jennifer A. Brody, Ming-Huei Chen, Michael G. Levin, Daniel I. Chasman et al.:
    Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors
    Circulation 2022 ARKIV / DOI
  • Helle Jørgensen, Erzsebet Horvath-Puho, Kristina Laugesen, Sigrid Kufaas Brækkan, John Bjarne Hansen, Henrik Toft Sørensen :
    Socioeconomic status and risk of incident venous thromboembolism
    Journal of Thrombosis and Haemostasis 2021 DOI
  • Espen Waage Skjeflo, Sigrid Kufaas Brækkan, Judith K Ludviksen, Omri Snir, Kristian Hindberg, Tom Eirik Mollnes et al.:
    Elevated plasma concentration of complement factor C5 is associated with risk of future venous thromboembolism
    Blood 2021 ARKIV / DOI
  • Magnus Edvardsen, Ellen-Sofie Hansen, Kristian Hindberg, Vania Maris Morelli, Thor Ueland, Pål Aukrust et al.:
    Combined effects of plasma von Willebrand factor and platelet measures on the risk of incident venous thromboembolism
    Blood 2021 ARKIV / DOI
  • Bjarne Østerud, Nadezhda Latysheva, Christian Schoergenhofer, Bernd Jilma, John-Bjarne Hansen, Omri Snir :
    A rapid, sensitive, and specific assay to measure TF activity based on chromogenic determination of thrombin generation
    Journal of Thrombosis and Haemostasis 25. November 2021 ARKIV / DOI
  • Tobias Frischmuth, Kristian Hindberg, Pål Aukrust, Thor Ueland, Sigrid K. Brækkan, John-Bjarne Hansen et al.:
    Plasma levels of leptin and risk of future incident venous thromboembolism
    Thrombosis and Haemostasis 2021 ARKIV / DOI
  • Magnus Edvardsen, Kristian Hindberg, Ellen-Sofie Hansen, Vania Maris Morelli, Thor Ueland, Pål Aukrust et al.:
    Plasma levels of von Willebrand factor and future risk of incident venous thromboembolism
    Blood Advances 2021 ARKIV / DOI
  • Hanne Skille, Benedikte Paulsen, Kristian Hveem, Marianne T. Severinsen, Maiken Elvestad Gabrielsen, Søren R. Kristensen et al.:
    Prothrombotic genotypes and risk of venous thromboembolism in occult cancer
    Thrombosis Research 2021 ARKIV / DOI
  • Gro Grimnes, Soerajja Bhoelan, Kristian Hindberg, Mark Davids, Max Nieuwdorp, Tom E. Mollnes et al.:
    Impact of a Vancomycin-Induced Shift of the Gut Microbiome in a Gram-Negative Direction on Plasma Factor VIII:C Levels: Results from a Randomized Controlled Trial
    Thrombosis and Haemostasis 2021 ARKIV / DOI
  • Benedikte Paulsen, Olga Vikhammer Gran, Marianne T. Severinsen, Jens Hammerstrøm, Søren Risom Kristensen, Suzanne C. Cannegieter et al.:
    Association of smoking and cancer with the risk of venous thromboembolism: the Scandinavian Thrombosis and Cancer cohort
    Scientific Reports 21. September 2021 ARKIV / DOI
  • Helle Jørgensen, Erzsébet Horváth-Puhó, Kristina Laugesen, Sigrid Kufaas Brækkan, John-Bjarne Hansen, Henrik Toft Sørensen :
    Risk of a permanent work-related disability pension after incident venous thromboembolism in Denmark: A population-based cohort study
    PLoS Medicine 2021 ARKIV / DOI
  • Carl Arne Løchen Arnesen, Katalin Veres, Erzsébet Horváth-Puhó, John-Bjarne Hansen, Henrik Toft Sørensen, Sigrid K. Brækkan :
    Estimated lifetime risk of venous thromboembolism in men and women in a Danish nationwide cohort: impact of competing risk of death
    European Journal of Epidemiology (EJE) 2021 ARKIV / DOI
  • Ellen-Sofie Hansen, Fridtjof Balteskard Rinde, Magnus Edvardsen, Kristian Hindberg, Nadezhda Latysheva, Pål Aukrust et al.:
    Elevated plasma D-dimer levels are associated with risk of future incident venous thromboembolism
    Thrombosis Research 2021 ARKIV / DOI
  • Grégoire Le Gal, Marc Carrier, Lana A. Castellucci, Adam Cuker, John-Bjarne Hansen, Frederikus A. Klok et al.:
    Development and implementation of common data elements for venous thromboembolism research: on behalf of SSC Subcommittee on official Communication from the SSC of the ISTH
    Journal of Thrombosis and Haemostasis 2021 DOI
  • Line Holtet Evensen, Aaron R. Folsom, James S. Pankow, John-Bjarne Hansen, Matthew Allison, Mary Cushman et al.:
    Hemostatic factors, inflammatory markers, and risk of incident venous thromboembolism: The Multi-Ethnic Study of Atherosclerosis
    Journal of Thrombosis and Haemostasis 2021 ARKIV / DOI
  • Cathrine Ramberg, Kristian Hindberg, Joseph S. Biedermann, Suzanne C. Cannegieter, Felix J. van der Meer, Omri Snir et al.:
    Rosuvastatin treatment decreases plasma procoagulant phospholipid activity after a VTE: A randomized controlled trial
    Journal of Thrombosis and Haemostasis 2021 ARKIV / DOI
  • Cathrine Ramberg, Line Wilsgård, Nadezhda Latysheva, Sigrid Kufaas Brækkan, Kristian Hindberg, Timofey Sovershaev et al.:
    Plasma procoagulant phospholipid clotting time and venous thromboembolism risk
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2021 ARKIV / DOI
  • Tobias Frischmuth, Kristian Hindberg, Maiken Elvestad Gabrielsen, Ben Michael Brumpton, Kristian Hveem, Sigrid Kufaas Brækkan et al.:
    Joint Effect of Multiple Prothrombotic Genotypes and Obesity on the Risk of Incident Venous Thromboembolism
    Thrombosis and Haemostasis 2021 ARKIV / DOI
  • Helle Jørgensen, Erzsébet Horváth-Puhó, Kristina Laugesen, Sigrid Brækkan, John-Bjarne Hansen, Henrik Toft Sørensen :
    Socioeconomic status and risk of incident venous thromboembolism
    Journal of Thrombosis and Haemostasis 2021 ARKIV / DOI
  • Ellen-Sofie Hansen, Kristian Hindberg, Nadezhda Latysheva, Pål Aukrust, Thor Ueland, John-Bjarne Hansen et al.:
    Plasma levels of growth differentiation factor 15 are associated with future risk of venous thromboembolism
    Blood 2020 ARKIV / DOI
  • Håkon Sandbukt Johnsen, Sigrid Kufaas Brækkan, Vania Maris Morelli, John-Bjarne Hansen :
    Platelet count and risk of major bleeding in venous thromboembolism
    Platelets 06. June 2020 ARKIV / DOI
  • Håkon Sandbukt Johnsen, Esben Bjøri, Kristian Hindberg, Sigrid Kufaas Brækkan, Vania Maris Morelli, John-Bjarne Hansen :
    Prothrombotic genotypes and risk of major bleeding in patients with incident venous thromboembolism
    Thrombosis Research 2020 ARKIV / DOI
  • Fridtjof Balteskard Rinde, Synne Grønvold Frønæs, Waleed Khalid Ghanima, Anders Vik, John-Bjarne Hansen, Sigrid Brækkan :
    D-dimer as a stand-alone test to rule out deep vein thrombosis
    Thrombosis Research 2020 ARKIV / DOI
  • Hanne Skille, Benedikte Paulsen, Kristian Hveem, Maiken Elvestad Gabrielsen, Ben Michael Brumpton, Kristian Hindberg et al.:
    Combined effects of five prothrombotic genotypes and cancer on the risk of a first venous thromboembolic event
    Journal of Thrombosis and Haemostasis 2020 ARKIV / DOI
  • Erin Mathisen Hald, Maja-Lisa Løchen, Ellisiv B Mathiesen, Tom Wilsgaard, Inger Njølstad, Sigrid Brækkan et al.:
    Atrial fibrillation, venous thromboembolism, ischemic stroke, and all-cause mortality: The Tromsø study
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2020 ARKIV / DOI
  • Erin Mathisen Hald, Maja-Lisa Løchen, Jostein Lappegård, Trygve Ellingsen, Ellisiv B. Mathiesen, Tom Wilsgaard et al.:
    Red Cell Distribution Width and Risk of Atrial Fibrillation and Subsequent Thromboembolism: The Tromsø Study
    TH Open 2020 ARKIV / DOI
  • Trond Børvik, Line Evensen, Vania Maris Morelli, Hasse Melbye, Sigrid Kufaas Brækkan, John-Bjarne Hansen :
    Impact of respiratory symptoms and oxygen saturation on the risk of incident venous thromboembolism-the Tromsø study.
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2020 ARKIV / DOI
  • Bjarne Østerud, Nadezhda Latysheva, John Bjarne Hansen, Omri Snir :
    “A rapid, sensitive, and specific assay to measure tissue factor activity based on chromogenic determination of thrombin generation”: reply
    Journal of Thrombosis and Haemostasis 2023 DOI
  • Casper Ullsten-Wahlund, Safak Caglayan, Christabel Esi Damoah, John Bjarne Hansen, Omri Snir :
    Hypoxia augments proinflammatory activation of endothelial cells towards a prothrombotic phenotype
    2021
  • Dana Meknas, John-Bjarne Hansen :
    Mannen, myten, legenden: Et dypdykk i John-Bjarne Hansens karriere innen forskning
    2020 FULLTEKST
  • John-Bjarne Hansen :
    John-Bjarne har utviklet en metode som kan avsløre hvem som har høy risiko for blodpropp: – Målet er å lage et legemiddel
    16. February 2020 FULLTEKST

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    Research interests

    Risk factors of venous thromboembolism

    Pathophysiology of venous thromboembolism

    Role of monocytes/macrophages in thrombogenesis

    Role of microparticles in thrombogenesis



    CV

    Academic degree

    1989                Cand.med (MD), University of Tromsø

    1997                Dr. med (PhD in cardiovascular medicine) University of Tromsø

    Previous academic positions

    1991-94          Research fellow, Univ. of Tromsø (Norw. Council on cardiovascular diseases)

    1994-95          Post.doc., University of Tromsø

    1996-2005      Associate professor in medicine, University of Tromsø (20-50% position)

    2006-2008      Professor I in Hematology, University of  Tromsø (100% position)

    2007-2008      Vice Dean for Research, Faculty of Health Sciences, University of Tromsø

    2008-2009      Visiting professor, The Scripps Research Institute, La Jolla, CA, USA

     Publications

    208 original full papers in peer-reviewed journals listed in PubMed and 22 review articles and book chapters- Contributed to more than 320 abstracts presented at and published in conjunction with scientific international meetings/conferences.

    Supervision of PhD-students

    Main supervisor for 24 completed PhD-thesis. Present supervision of 13 PhD-students as main supervisor and mentor for 5 postdoctors


    FARM F4.210A