Bilde av Martinez, Inigo Zubiavrre
Bilde av Martinez, Inigo Zubiavrre
Department of Clinical Medicine inigo.martinez@uit.no +4777644686 +47 986 18 205 Tromsø MH L7.207

Inigo Zubiavrre Martinez


Professor in Cell Biology

Job description

Group leader for the Molecular inflammation Research Group at IKM. Over 20 years documented experience in accademia, with  track records in both teaching and research. The researcher focus of the Group is on investigating the role of the tumor stroma and fibroblasts as regulators of tumor immnunology, and  in regulating tumor responses to radiotherapy and immunotherapy.


  • Rodrigo Berzaghi, Stian Tornaas, Kristin Lode, Turid Hellevik, Inigo Zubiavrre Martinez :
    Ionizing Radiation Curtails Immunosuppressive Effects From Cancer-Associated Fibroblasts on Dendritic Cells
    Frontiers in Immunology 2021 ARKIV / DOI
  • Turid Hellevik, Rodrigo Berzaghi, Kristin Lode, Md Ashraful Islam, Inigo Zubiavrre Martinez :
    Immunobiology of cancer-associated fibroblasts in the context of radiotherapy
    Journal of Translational Medicine 18. October 2021 ARKIV / DOI
  • Rodrigo Berzaghi, Md Ashraful Islam, Turid Hellevik, Inigo Zubiavrre Martinez :
    Secretion rates and protein composition of extracellular vesicles released by cancer-associated fibroblasts after radiation
    Journal of radiation research 19. February 2021 ARKIV / DOI
  • Ann Belén Carillo-Gálvez, Juan Esteban Quintero, René Rodrígez, Sofía T. Menéndez, M. Victoria Gonzàlez, Verónica Blanco-Lorenzo et al.:
    GARP promotes the proliferation and therapeutic resistance of bone sarcoma cancer cells through the activation of TGF-beta
    Cell Death and Differentiation 23. September 2020 ARKIV / DOI
  • Nannan Yang, Kristin Lode, Rodrigo Berzaghi, Md Ashraful Islam, Inigo Zubiavrre Martinez, Turid Hellevik :
    Irradiated tumor fibroblasts avoid immune recognition and retain immunosuppressive functions over NK cells
    Frontiers in Immunology 06. December 2020 ARKIV / DOI
  • Sabin Bhandari, Ruomei Li, Jaione Simon-Santamaria, Peter Anthony McCourt, Steinar Daae Johansen, Bård Smedsrød et al.:
    Transcriptome and proteome profiling reveal complementary scavenger and immune features of rat liver sinusoidal endothelial cells and liver macrophages
    BMC Molecular and Cell Biology 2020 ARKIV / DOI
  • Thomas Karsten Kilvær, Mehrdad Rakaee, Turid Hellevik, Jørg Vik, Luigi de Petris, Tom Dønnem et al.:
    Differential prognostic impact of platelet-derived growth factor receptor Expression in NSCLC
    Scientific Reports 2019 ARKIV / DOI
  • Armin Alibegovic, Rok Blagus, Inigo Zubiavrre Martinez :
    Safranin O without fast green is the best staining method for testing the degradation of macromolecules in a cartilage extracellular matrix for the determination of the postmortem interval
    Forensic Science, Medicine, and Pathology 2019 DOI
  • Md Ashraful Islam, Vegard Fossum, Ann Kristin Hansen, Ilona Urbarova, Gunnar Knutsen, Inigo Zubiavrre Martinez :
    In vitro chondrogenic potency of surplus chondrocytes from autologous transplantation procedures does not predict short-term clinical outcomes
    BMC Musculoskeletal Disorders 2019 ARKIV / DOI
  • Md Ashraful Islam, Ilona Urbarova, Jack-Ansgar Bruun, Inigo Zubiavrre Martinez :
    LARGE-SCALE SECRETOME ANALYSES UNVEIL THE SUPERIOR IMMUNOSUPPRESSIVE PHENOTYPE OF UMBILICAL CORD STROMAL CELLS AS COMPARED TO OTHER ADULT MESENCHYMAL STROMAL CELLS
    European Cells and Materials 20. February 2019 ARKIV / DOI
  • Rodrigo Berzaghi, Muhammad Asad Akhtar, Md Ashraful Islam, Brede Dille Pedersen, Turid Hellevik, Inigo Zubiavrre Martinez :
    Fibroblast-Mediated Immunoregulation of Macrophage Function Is Maintained after Irradiation
    Cancers 14. May 2019 ARKIV / DOI
  • Anowarul Habib, Juha Vierinen, Md Ashraful Islam, Inigo Zubiavrre Martinez, Frank Melandsø :
    In Vitro Volume Imaging of Articular Cartilage Using Chirp-Coded High Frequency Ultrasound
    Proceedings - IEEE Ultrasonics Symposium 2018 DOI
  • Inigo Zubiavrre Martinez, Anthony J. Chalmers, Turid Hellevik :
    Radiation-induced transformation of immunoregulatory networks in tumor stroma
    Frontiers in Immunology 26. July 2018 ARKIV / DOI
  • Thomas Karsten Kilvær, Mehrdad Rakaee, Turid Hellevik, Arne Östman, Carina Strell, Roy M. Bremnes et al.:
    Tissue analyses reveal a potential immune-adjuvant function of FAP-1 positive fibroblasts in non-small cell lung cancer
    PLOS ONE 2018 ARKIV / DOI
  • Sigurd Hald, Mehrdad Rakaee, Inigo Zubiavrre Martinez, Elin Richardsen, Samer Al-Saad, Erna Elise Paulsen et al.:
    LAG-3 in Non-Small-cell Lung Cancer: Expression in Primary Tumors and Metastatic Lymph Nodes Is Associated With Improved Survival
    Clinical Lung Cancer 2018 DOI
  • Ann Kristin Hansen, Yngve Anton Figenschau, Inigo Zubiavrre Martinez :
    Co-expression of 1α-hydroxylase and vitamin D receptor in human articular chondrocytes
    BMC Musculoskeletal Disorders 2017 ARKIV / DOI
  • Michel Herranz Carnero, Angel Moldes-Anaya, Bengt Erik Haug, Turid Hellevik, Inigo Zubiavrre Martinez :
    Innovative molecular imaging technique for Granzyme-B characterization as an emerging biomarker for radio-immunotherapy combinations
    2022
  • Inigo Zubiavrre Martinez, Turid Hellevik :
    Exploring the impact of radiotherapy on Cancer-Associated Fibroblasts by antigen-specific PET-imaging
    2022
  • Inigo Zubiavrre Martinez, Rodrigo Berzaghi, Kristin Lode, Turid Hellevik :
    Cancer-associated fibroblasts in radiotherapy: Bystanders or protagonists?
    2022
  • Michel Herranz Carnero, Kristin Lode, Yngve Guttormsen, Turid Hellevik, Inigo Zubiavrre Martinez :
    Establishment of PET-tracer 18F-AlF-FAPI-74 in two animal tumor models
    2022
  • Inigo Zubiavrre Martinez, Turid Hellevik, Md Ashraful Islam, Rodrigo Berzaghi, Michel Herranz Carnero, Kristin Lode :
    Exploring the immunoregulatory potential of radiotherapy by non-invasive PET imaging
    2022
  • Inigo Zubiavrre Martinez, Turid Hellevik, Rodrigo Berzaghi, Kristin Lode, Nannan Yang :
    Cancer-Associated Fibroblasts in radiotherapy: bystanders or protagonists?
    2022
  • Inigo Zubiavrre Martinez, Turid Hellevik, Geir Hevnskjel Ringvold :
    På labben: Slik sloss vi mot kreft
    22. September 2021
  • Michel Herranz Carnero, Turid Hellevik, Inigo Zubiavrre Martinez :
    Development of novel immuno-PET tracers for in vivo imaging of tumor-associated immunity.
    2021
  • Turid Hellevik, Inigo Zubiavrre Martinez, Michel Herranz Carnero, Md Ashraful Islam, Rodrigo Berzaghi, Kristin Lode :
    Exploring the immunoregulatory potential of radiotherapy in preclinical models
    2021
  • Michel Herranz Carnero, Kristin Lode, Turid Hellevik, Inigo Zubiavrre Martinez :
    In vivo protocols and pilot studies for immune-PET imaging
    2021
  • Kristin Lode, Rodrigo Berzaghi, Michel Herranz Carnero, Turid Hellevik, Inigo Zubiavrre Martinez :
    Regulatory functions of cancer associated fibroblasts following radiation
    2021
  • Inigo Zubiavrre Martinez, Turid Hellevik :
    Cancer research by the Molecular Inflammation Research Group at IKM, UiT.
    2021
  • Md Ashraful Islam, Hidde L. Ploegh, Turid Hellevik, Inigo Zubiavrre Martinez :
    Single-chain variable fragment (scFv) tracer development for immuno-PET imaging
    2021
  • Inigo Zubiavrre Martinez, Turid Hellevik :
    Immuno-PET tracers for lung cancer
    2021
  • Inigo Zubiavrre Martinez, Turid Hellevik :
    Radiobiology research in Northern-Norway
    2021
  • Turid Hellevik, Rodrigo Berzaghi, Inigo Zubiavrre Martinez, Kristin Lode :
    Immuno-radiobiology of cancer-associated fibroblasts
    2021
  • Md Ashraful Islam, Turid Hellevik, Inigo Zubiavrre Martinez :
    Immuno-PET imaging of the tumor-immune landscape using engineered antibody fragments
    2021
  • Jan-Dag Pohlmann, Andreas Bryhn, Argyris Sapounidis, Arvydas Svagzdys, Ayesha Taylor, Azza El Ganainy et al.:
    Joint EIFAAC/ICES/GFCM Working Group on Eels (WGEEL)
    2021
  • Turid Hellevik, Inigo Zubiavrre Martinez :
    Immunoregulatory properties of irradiated fibroblasts
    2020
  • Inigo Zubiavrre Martinez, Turid Hellevik :
    Immuno-PET technology in preclinical cancer models
    2019
  • Rodrigo Berzaghi, Muhammad Asad Akhtar, Stian Tornaas, Turid Hellevik, Inigo Zubiavrre Martinez :
    Impact of ionizing radiation on immunoregulatory roles of Cancer-Associated Fibroblasts
    2019
  • Turid Hellevik, Inigo Zubiavrre Martinez :
    Alternative biomarkører til Immunterapi
    Tidsskrift for Den norske legeforening 07. October 2019 DOI
  • Turid Hellevik, Inigo Zubiavrre Martinez :
    Potensialet til Immuno-PET avbildning for Immunoterapi og Stråleterapi
    2019
  • Turid Hellevik, Inigo Zubiavrre Martinez :
    Immuno-PET imaging in Radiotherapy & Immunotherapy research
    2019
  • Inigo Zubiavrre Martinez, Turid Hellevik :
    Tumor fibroblasts in the radiotherapy context
    2019
  • Sabin Bhandari, Ruomei Li, Ingelin Kyrrestad, Jack-Ansgar Bruun, Ilona Urbarova, Bård Smedsrød et al.:
    Effect of glucocorticoids on liver sinusoidal endothelial cells in vitro
    2019
  • Inigo Zubiavrre Martinez :
    Role of fibroblasts in lung tumor responses to therapy
    2018
  • Turid Hellevik, Inigo Zubiavrre Martinez :
    Strategier for kombinert Stråleterapi & Immunterapi
    2018
  • Turid Hellevik, Inigo Zubiavrre Martinez :
    Optimizing radiotherapy-Immunotherapy combinations in preclinical models
    2018
  • Mathias Bruvoll, Inigo Zubiavrre Martinez, Turid Hellevik :
    UiT-forskere tildelt millioner fra Kreftforeningen
    01. November 2018
  • Ashraful Islam, Vegard Fossum, Ann Kristin Hansen, Ilona Urbarova, Gunnar Knutsen, Inigo Zubiavrre Martinez :
    In vitro chondrogenic potency of surplus chondrocytes from ACI does not predict short-term clinical outcomes.
    2018
  • Per-Christian Johansen, Turid Hellevik, Inigo Zubiavrre Martinez :
    Millionstøtte til preklinisk kreftforskning
    17. December 2018
  • Rodrigo Berzaghi, Muhammad Asad Akhtar, Stian Tornaas, Turid Hellevik, Inigo Zubiavrre Martinez :
    Radiation abrogates CAF-mediated immunosuppressive effects on dendritic cells
    2018
  • Inigo Zubiavrre Martinez, Turid Hellevik :
    Tumor fibroblasts at the intersection of Radiotherapy and Immunotherapy
    2017

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