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Department of Clinical Medicine inigo.martinez@uit.no +4777644686 +47 986 18 205 Tromsø MH L7.207

Inigo Zubiavrre Martinez

Professor in Cell Biology

Job description

Group leader for the Molecular inflammation Research Group at IKM. Over 20 years documented experience in accademia, with  track records in both teaching and research. The researcher focus of the Group is on investigating the role of the tumor stroma and fibroblasts as regulators of tumor immnunology, and  in regulating tumor responses to radiotherapy and immunotherapy.

  • Berzaghi, Rodrigo; Islam, Md Ashraful; Hellevik, Turid; Martinez, Inigo Zubiavrre. Secretion rates and protein composition of extracellular vesicles released by cancer-associated fibroblasts after radiation. Journal of radiation research 2021. ISSN 0449-3060.s doi: 10.1093/jrr/rrab018.
  • Berzaghi, Rodrigo; Tornaas, Stian; Lode, Kristin; Hellevik, Turid; Martinez, Inigo Zubiavrre. Ionizing Radiation Curtails Immunosuppressive Effects From Cancer-Associated Fibroblasts on Dendritic Cells. Frontiers in Immunology 2021; Volum 12. ISSN 1664-3224.s doi: 10.3389/fimmu.2021.662594.
  • Hellevik, Turid; Berzaghi, Rodrigo; Lode, Kristin; Islam, Md Ashraful; Martinez, Inigo Zubiavrre. Immunobiology of cancer-associated fibroblasts in the context of radiotherapy. Journal of Translational Medicine 2021. ISSN 1479-5876.s doi: 10.1186/s12967-021-03112-w.
  • Yang, Nannan; Lode, Kristin; Berzaghi, Rodrigo; Islam, Md Ashraful; Martinez, Inigo Zubiavrre; Hellevik, Turid. Irradiated tumor fibroblasts avoid immune recognition and retain immunosuppressive functions over NK cells. Frontiers in Immunology 2020; Volum 11. ISSN 1664-3224.s doi: 10.3389/fimmu.2020.602530.
  • Carillo-Gálvez, Ann Belén; Quintero, Juan Esteban; Rodrígez, René; Menéndez, Sofía T.; Gonzàlez, M. Victoria; Blanco-Lorenzo, Verónica; Allonca, Eva; Farias, Virgínea de Araújo; González-Correa, Juan Elías; Erill-Sagalés, Nadina; Martinez, Inigo Zubiavrre; Hellevik, Turid; Sánchez-Hernández, Sabina; Muñoz, Pilar; Zurita, Federico; Martín, Francisco; Rodriguez-Manzaneque, Juan Carlos; Anderson, Per. GARP promotes the proliferation and therapeutic resistance of bone sarcoma cancer cells through the activation of TGF-beta. Cell Death and Differentiation 2020. ISSN 1350-9047.s doi: 10.1038/s41419-020-03197-z.
  • Bhandari, Sabin; Li, Ruomei; Simon-Santamaria, Jaione; McCourt, Peter Anthony; Johansen, Steinar Daae; Smedsrød, Bård; Martinez, Inigo Zubiavrre; Sørensen, Karen Kristine. Transcriptome and proteome profiling reveal complementary scavenger and immune features of rat liver sinusoidal endothelial cells and liver macrophages. BMC Molecular and Cell Biology 2020; Volum 21. ISSN 2661-8850.s doi: 10.1186/s12860-020-00331-9.
  • Alibegovic, Armin; Blagus, Rok; Martinez, Inigo Zubiavrre. Safranin O without fast green is the best staining method for testing the degradation of macromolecules in a cartilage extracellular matrix for the determination of the postmortem interval. Forensic Science, Medicine, and Pathology 2019. ISSN 1547-769X.s doi: 10.1007/s12024-019-00208-0.
  • Islam, Md Ashraful; Fossum, Vegard; Hansen, Ann Kristin; Urbarova, Ilona; Knutsen, Gunnar; Martinez, Inigo Zubiavrre. In vitro chondrogenic potency of surplus chondrocytes from autologous transplantation procedures does not predict short-term clinical outcomes. BMC Musculoskeletal Disorders 2019; Volum 20:19. ISSN 1471-2474.s 1 - 15.s doi: 10.1186/s12891-018-2380-4.
  • Islam, Md Ashraful; Urbarova, Ilona; Bruun, Jack-Ansgar; Martinez, Inigo Zubiavrre. LARGE-SCALE SECRETOME ANALYSES UNVEIL THE SUPERIOR IMMUNOSUPPRESSIVE PHENOTYPE OF UMBILICAL CORD STROMAL CELLS AS COMPARED TO OTHER ADULT MESENCHYMAL STROMAL CELLS. European Cells and Materials 2019; Volum 37. ISSN 1473-2262.s 153 - 174.s doi: 10.22203/eCM.v037a10.
  • Berzaghi, Rodrigo; Akhtar, Muhammad Asad; Islam, Md Ashraful; Pedersen, Brede Dille; Hellevik, Turid; Martinez, Inigo Zubiavrre. Fibroblast-Mediated Immunoregulation of Macrophage Function Is Maintained after Irradiation. Cancers 2019; Volum 11 (5). ISSN 2072-6694.s 1 - 18.s doi: 10.3390/cancers11050689.
  • Kilvær, Thomas Karsten; Rakaee, Mehrdad; Hellevik, Turid; Vik, Jørg; de Petris, Luigi; Dønnem, Tom; Strell, Carina; Østman, Arne; Rasmussen Busund, Lill-Tove; Martinez, Inigo Zubiavrre. Differential prognostic impact of platelet-derived growth factor receptor Expression in NSCLC. Scientific Reports 2019; Volum 9:10163. ISSN 2045-2322.s 1 - 11.s doi: 10.1038/s41598-019-46510-3.
  • Kilvær, Thomas Karsten; Rakaee, Mehrdad; Hellevik, Turid; Östman, Arne; Strell, Carina; Bremnes, Roy M.; Busund, Lill-Tove; Dønnem, Tom; Martinez, Inigo Zubiavrre. Tissue analyses reveal a potential immune-adjuvant function of FAP-1 positive fibroblasts in non-small cell lung cancer. PLOS ONE 2018; Volum 13 (2). ISSN 1932-6203.s doi: 10.1371/journal.pone.0192157.
  • Hald, Sigurd; Rakaee, Mehrdad; Martinez, Inigo Zubiavrre; Richardsen, Elin; Al-Saad, Samer; Paulsen, Erna Elise; Blix, Egil Støre; Kilvær, Thomas Karsten; Andersen, Sigve; Busund, Lill-Tove; Bremnes, Roy M.; Dønnem, Tom. LAG-3 in Non-Small-cell Lung Cancer: Expression in Primary Tumors and Metastatic Lymph Nodes Is Associated With Improved Survival. Clinical Lung Cancer 2018; Volum 19 (3). ISSN 1525-7304.s 249 - 259.e2.s doi: 10.1016/j.cllc.2017.12.001.
  • Martinez, Inigo Zubiavrre; Chalmers, Anthony J.; Hellevik, Turid. Radiation-induced transformation of immunoregulatory networks in tumor stroma. Frontiers in Immunology 2018; Volum 9:1679. ISSN 1664-3224.s 1 - 16.s doi: 10.3389/fimmu.2018.01679.
  • Grinde, Maria Tunset; Vik, Jørg; Camilio, Ketil Andre; Martinez, Inigo Zubiavrre; Hellevik, Turid. Ionizing radiation abrogates the pro-tumorigenic capacity of cancer-Associated fibroblasts co-implanted in xenografts. Scientific Reports 2017; Volum 7. ISSN 2045-2322.s doi: 10.1038/srep46714.
  • Magnussen, Synnøve; Hadler-Olsen, Elin Synnøve; Costea, Daniela Elena; Berg, Eli; Cavalcanti Jacobsen, Cristiane de Albuquerque; Mortensen, Bente; Salo, Tuula; Martinez, Inigo Zubiavrre; Winberg, Jan-Olof; Uhlin-Hansen, Lars; Svineng, Gunbjørg. Cleavage of the urokinase receptor (uPAR) on oral cancer cells: Regulation by transforming growth factor - beta1 (TGF-beta1) and potential effects on migration and invasion. BMC Cancer 2017; Volum 17. ISSN 1471-2407.s doi: 10.1186/s12885-017-3349-7.
  • Eksteen, Mariana; Heide, Gøril; Tiller, Heidi; Zhou, Yan; Nedberg, Nora Hersoug; Martinez, Inigo Zubiavrre; Husebekk, Anne; Skogen, Bjørn Ragnar; Stuge, Tor Brynjar; Kjær, Mette. Anti-human platelet antigen (HPA)-1a antibodies may affect trophoblast functions crucial for placental development: A laboratory study using an in vitro model. Reproductive Biology and Endocrinology 2017; Volum 15:28. ISSN 1477-7827.s 1 - 8.s doi: 10.1186/s12958-017-0245-6.
  • Hansen, Ann Kristin; Figenschau, Yngve Anton; Martinez, Inigo Zubiavrre. Co-expression of 1α-hydroxylase and vitamin D receptor in human articular chondrocytes. BMC Musculoskeletal Disorders 2017; Volum 18:432. ISSN 1471-2474.s 1 - 13.s doi: 10.1186/s12891-017-1791-y.
  • Islam, Md Ashraful; Romijn, Elisabeth Inge; Lilledahl, Magnus Borstad; Martinez, Inigo Zubiavrre. Non-linear optical microscopy as a novel quantitative and label-free imaging modality to improve the assessment of tissue-engineered cartilage. Osteoarthritis and Cartilage 2017; Volum 25 (10). ISSN 1063-4584.s 1729 - 1737.s doi: 10.1016/j.joca.2017.06.008.
  • Islam, Md Ashraful; Hansen, Ann Kristin; Mennan, Claire; Martinez, Inigo Zubiavrre. Mesenchymal stromal cells from human umbilical cords display poor chondrogenic potential in scaffold-free three dimensional cultures. (fulltekst) European Cells and Materials 2016; Volum 31. ISSN 1473-2262.s 407 - 424.
  • Kilvær, Thomas Karsten; Rakaeekhanehkenari, Mehrdad; Hellevik, Turid; Al-Saad, Samer; Paulsen, Erna-Elise; Bremnes, Roy M.; Busund, Lill-Tove; Dønnem, Tom; Martinez, Inigo Zubiavrre. Cancer associated fibroblasts in stage I-IIIA NSCLC: Prognostic impact and their correlations with tumor molecular markers. PLOS ONE 2015; Volum 10:e0134965 (8). ISSN 1932-6203.s doi: 10.1371/journal.pone.0134965.
  • Gorchs, Laia; Hellevik, Turid; Bruun, Jack-Ansgar; Camilio, Ketil Andre; Al-Saad, Samer; Stuge, Tor Brynjar; Martinez, Inigo Zubiavrre. Cancer-associated fibroblasts from lung tumors maintain their immunosuppressive abilities after high-dose irradiation. Frontiers in Oncology 2015; Volum 5:87. ISSN 2234-943X.s doi: 10.3389/fonc.2015.00087.
  • Ben-Batalla, Isabel; Cubas-Cordova, Miguel; Udonta, Florian; Wroblewski, Mark; Waizenegger, Jonas S.; Janning, Melanie; Sawall, Stefanie; Gensch, Victoria; Zhao, Lin; Martinez, Inigo Zubiavrre; Riecken, Kristoffer; Fehse, Boris; Pantel, Klaus; Bokemeyer, Carsten; Loges, Sonja. Cyclooxygenase-2 blockade can improve efficacy of VEGF-targeting drugs. OncoTarget 2015; Volum 6 (8). ISSN 1949-2553.s 6341 - 6358.s doi: 10.18632/oncotarget.3437.
  • Hansen, Ann Kristin; Indrevik, Jill-Tove; Figenschau, Yngve Anton; Martinez, Inigo Zubiavrre; Sveinbjørnsson, Baldur. Human articular chondrocytes express functional leukotriene B<sub>4</sub> receptors. Journal of Anatomy 2015; Volum 226 (3). ISSN 0021-8782.s 268 - 277.s doi: 10.1111/joa.12275.
  • Hellevik, Turid; Martinez, Inigo Zubiavrre. Radiotherapy and the tumor stroma: the importance of dose and fractionation. Frontiers in Oncology 2014; Volum 4:1. ISSN 2234-943X.s doi: 10.3389/fonc.2014.00001.
  • Bendiksen, Signy; Martinez, Inigo Zubiavrre; Tümmler, Conny; Knutsen, Gunnar; Elvenes, Jan; Olsen, Elisabeth; Olsen, Randi; Moens, Ugo. Human endogenous retrovirus W activity in cartilage of osteoarthritis patients. BioMed Research International 2014; Volum 2014. ISSN 2314-6133.s doi: 10.1155/2014/698609.
  • Hellevik, Turid; Pettersen, Ingvild; Berg, Vivian; Bruun, Jack-Ansgar; Bartnes, Kristian; Busund, Lill-Tove; Chalmers, Anthony; Bremnes, Roy M.; Martinez, Inigo Zubiavrre. Changes in the secretory profile of NSCLC-associated fibroblasts after ablative radiotherapy: Potential impact on angiogenesis and tumor growth. (fulltekst) Translational Oncology 2013; Volum 6 (1). ISSN 1944-7124.s 66 - 74.s doi: 10.1593/tlo.12349.
  • Martinez, Inigo Zubiavrre; Fenton, Christopher Graham; Taman, Hagar Mohamed; Pettersen, ingvild; Hellevik, Turid; Paulssen, Ruth H. Tumorigenic responses of Cancer-Associated Fibroblasts after ablative radiotherapy: A transcriptome-profiling study. Journal of Cancer Therapy 2013; Volum 4 (1). ISSN 2151-1934.s 208 - 250.s doi: 10.4236/jct.2013.41031.
  • Hellevik, Turid; Pettersen, ingvild; Berg, Vivian; Winberg, Jan-Olof; Moe, Bjørn Torvald Greve; Bartnes, Kristian; Paulssen, Ruth H; Busund, Lill-Tove; Bremnes, Roy M.; Chalmers, Antony; Martinez, Inigo Zubiavrre. Cancer-associated fibroblasts from human NSCLC survive ablative doses of radiation but their invasive capacity is reduced. Radiation Oncology 2012; Volum 7. ISSN 1748-717X.s doi: 10.1186/1748-717X-7-59.
  • Serrano, Maria José; Rovira, Pedro Sanchez; Martinez, Inigo Zubiavrre; Rodriguez, Miguel Delgado; Fernandez, Monica; Lorente, Jose A.. Dynamics of circulating tumor cells in early breast cancer under neoadjuvant therapy. Experimental and Therapeutic Medicine 2012; Volum 4 (1). ISSN 1792-0981.s 43 - 48.s doi: 10.3892/etm.2012.540.
  • Eilertsen, Marte; Pettersen, ingvild; Andersen, Sigve; Martinez, Inigo Zubiavrre; Dønnem, Tom; Busund, Lill-Tove; Bremnes, Roy M.. In NSCLC, VEGF-A Response to Hypoxia May Differ between Squamous Cell and Adenocarcinoma Histology. (sammendrag) Anticancer Research 2012; Volum 32 (11). ISSN 0250-7005.s 4729 - 4736.
  • Martinez, Inigo Zubiavrre; Annala, Tuija; Polacek, Martin. Behavior of Human Articular Chondrocytes During In Vivo Culture in Closed, Permeable Chambers. Cell Medicine 2012. ISSN 2155-1790.s doi: 10.3727/215517912X647226.
  • Bremnes, Roy M.; Dønnem, Tom; Al-Saad, Samer; Al-Shibli, Khalid Ibrahim; Andersen, Sigve; Sirera, Rafael; Camps, Carlos; Martinez, Inigo Zubiavrre; Busund, Lill-Tove Rasmussen. The Role of Tumor Stroma in Cancer Progression and Prognosis Emphasis on Carcinoma-Associated Fibroblasts and Non-small Cell Lung Cancer. Journal of Thoracic Oncology 2011; Volum 6 (1). ISSN 1556-0864.s 209 - 217.s doi: 10.1097/JTO.0b013e3181f8a1bd.
  • Polacek, Martin; Bruun, Jack-Ansgar; Elvenes, Jan; Figenschau, Yngve; Martinez, Inigo Zubiavrre. The secretory profiles of cultured human articular chondrocytes and mesenchymal stem cells: implications for autologous cell transplantation strategies. Cell Transplantation 2011; Volum 20 (9). ISSN 0963-6897.s 1381 - 1393.s doi: 10.3727/096368910X550215.
  • Polacek, Martin; Bruun, Jack-Ansgar; Johansen, Oddmund; Martinez, Inigo Zubiavrre. Differences in the Secretome of Cartilage Explants and Cultured Chondrocytes Unveiled by SILAC Technology. Journal of Orthopaedic Research 2010; Volum 28 (8). ISSN 0736-0266.s 1040 - 1049.s doi: 10.1002/jor.21067.
  • Serrano Fernandez, Maria Jose; Alvarez Merino, Juan Carlos; Martinez, Inigo Zubiavrre; Fernandez Garcia, Ana; Sanchez Rovira, Pedro; Lorente, Jose Antonio. Clinical relevance associated to the analysis of circulating tumour cells in patients with solid tumours. Clinical and Translational Oncology 2009; Volum 11 (10). ISSN 1699-048X.s 659 - 668.s doi: 10.1007/s12094-009-0421-z.
  • Polacek, Martin; Bruun, Jack-Ansgar; Johansen, oddmund; Martinez, Inigo Zubiavrre. Differences in the secretome of cartilage explants and cultured chondrocytes unveiled by SILAC technology. Journal of Orthopaedic Research 2009. ISSN 0736-0266.
  • Elvenes, Jan; Knutsen, Gunnar; Johansen, oddmund; Moe, Bjørn Torvald Greve; Martinez, Inigo Zubiavrre. Development of a new method to harvest chondroprogenitor cells from underneath cartilage defects in the knees. Journal of Orthopaedic Science 2009; Volum 14 (4). ISSN 0949-2658.s 410 - 417.s doi: 10.1007/s00776-009-1349-4.
  • Elvevold, kjetil helge; Smedsrød, Bård; Martinez, Inigo Zubiavrre. The liver sinusoidal endothelial cell: a cell type of controversial and confusing identity. American Journal of Physiology - Gastrointestinal and Liver Physiology 2008; Volum 294. ISSN 0193-1857.s G391 - G400.s doi: 10.1152/ajpgi.00167.2007.
  • Martinez, Inigo Zubiavrre; Nedredal, Geir Ivar; Øie, Christina Ionica; Warren, A; Johansen, oddmund; Le Couteur, D.G.; Smedsrød, Bård. The influence of oxygen tension on the structure and function of isolated liver sinusoidal endothelial cells. Comparative Hepatology 2008; Volum 7. ISSN 1476-5926.s doi: 10.1186/1476-5926-7-4.
  • Martinez, Inigo Zubiavrre; Olsen, R; Bertheussen, K; Johansen, oddmund. Redifferentiation of In Vitro Expanded Adult Articular Chondrocytes by Combining the Hanging-Drop Cultivation Method With Hypoxic Environment. Cell Transplantation 2008; Volum 17 (8). ISSN 0963-6897.s 987 - 996.
  • Martinez, Inigo Zubiavrre; Elvenes, Jan; Olsen, Randi Elisabeth; Bertheussen, Kjell; Johansen, oddmund. Re-differentiation of in vitro expasnded adult articular chondrocytes by combining the hanging-drop cultivation method with hypoxic environment. Cell Transplantation 2008. ISSN 0963-6897.
  • Elvevold, kjetil helge; Smedsrød, Bård; Martinez, Inigo Zubiavrre. The liver sinusoidal endothelial cell: a cell type of controversial and confusing identity. American Journal of Physiology 2007 (294). ISSN 0002-9513.s G391 - G400.
  • Martinez, Inigo Zubiavrre; Chakrabarti, Sabyasachi; Hellevik, Turid; Morehead, Jennifer; Fowler, Kimberley; Andrews, Norma W.. Synaptotagmin VII regulates Ca(2+)-dependent exocytosis of lysosomes in fibroblasts. Journal of Cell Biology 2000; Volum 148. ISSN 0021-9525.s 1141 - 1149.
  • Hellevik, Turid; Martinez, Inigo Zubiavrre; Olsen, randi; Toh, B.H.; Webster, Paul; Smedsrød, Bård. Transport of residual endocytosed products into terminal lysosomes occurs slowly in rat liver endothelial cells. Hepatology 1998; Volum 28 (5). ISSN 0270-9139.s 1378 - 1389.
  • Martinez, Inigo Zubiavrre; Sveinbjørnsson, Baldur; Vidal-Vanaclocha, Fernando; Smedsrød, Bård. Inflammatory agents modulate the endocytic activity of liver sinusoidal endothelial cells. 1997 ISBN 90-803856-1-1.s 351 - 354.
  • Martinez, Inigo Zubiavrre; Sveinbjørnsson, Baldur; Smedsrød, Bård. Nitric oxide down-regulates endocytosis in rat liver endothelial cells. Biochemical and Biophysical Research Communications - BBRC 1996; Volum 222. ISSN 0006-291X.s 688 - 693.
  • Asumendi, A.; Alvarez, A.; Martinez, Inigo Zubiavrre; Smedsrød, Bård; Vidal-Vanaclocha, Fernando. Hepatic sinusoidal endothelium heterogeneity with respect to mannose receptor activity is IL-1 dependent. Hepatology 1996; Volum 23. ISSN 0270-9139.s 1521 - 1529.
  • Asumendi, Aintzane; Alvarez, A; Martinez, Inigo Zubiavrre; Smedsrød, Bård; Vidal-Vanaclocha, Fernando. Interleukin-1-dependent stimulation of mannose receptor activity in the hepatic sinusoidal endothelium. 1995.s 209 - 211.
  • Martinez, Inigo Zubiavrre; Sveinbjørnsson, Baldur; Vidal-Vanaclocha, Fernando; Asumendi, Aintzane; Smedsrød, Bård. Differential cytokine-mediated modulation of endocytosis in rat liver endothelial cells. Biochemical and Biophysical Research Communications - BBRC 1995; Volum 212. ISSN 0006-291X.s 235 - 241.
  • Martinez, Inigo Zubiavrre; Berzaghi, Rodrigo; Lode, Kristin; Hellevik, Turid. Cancer-associated fibroblasts in radiotherapy: Bystanders or protagonists?. ESTRO-2022 2022-05-06 - 2022-05-10 2022.
  • Martinez, Inigo Zubiavrre; Hellevik, Turid; Islam, Md Ashraful; Berzaghi, Rodrigo; Herranz Carnero, Michel; Lode, Kristin. Exploring the immunoregulatory potential of radiotherapy by non-invasive PET imaging. National 180oN CONFERENCE 2021 2022-03-29 - 2022-03-31 2022.
  • Herranz Carnero, Michel; Lode, Kristin; Guttormsen, Yngve; Hellevik, Turid; Martinez, Inigo Zubiavrre. Establishment of PET-tracer 18F-AlF-FAPI-74 in two animal tumor models. National 180oN CONFERENCE 2022 2022-03-29 - 2022-03-31 2022.
  • Herranz Carnero, Michel; Moldes-Anaya, Angel; Haug, Bengt Erik; Hellevik, Turid; Martinez, Inigo Zubiavrre. Innovative molecular imaging technique for Granzyme-B characterization as an emerging biomarker for radio-immunotherapy combinations. National 180oN CONFERENCE 2022 2022-03-29 - 2022-03-31 2022.
  • Martinez, Inigo Zubiavrre; Hellevik, Turid. Exploring the impact of radiotherapy on Cancer-Associated Fibroblasts by antigen-specific PET-imaging. Fifth Conference on Precision Image-Guided Small Animal Radiotherapy 2022-03-21 - 2022-03-23 2022.
  • Martinez, Inigo Zubiavrre; Hellevik, Turid. Cancer research by the Molecular Inflammation Research Group at IKM, UiT.. User meeting byThe Norwegian Cancer Society 2021-04-09 - 2021-04-09 2021.
  • Hellevik, Turid; Martinez, Inigo Zubiavrre; Herranz Carnero, Michel; Islam, Md Ashraful; Berzaghi, Rodrigo; Lode, Kristin. Exploring the immunoregulatory potential of radiotherapy in preclinical models. 180oN Autumn Webinar 2021 2021-10-01 - 2021-10-01 2021.
  • Herranz Carnero, Michel; Lode, Kristin; Hellevik, Turid; Martinez, Inigo Zubiavrre. In vivo protocols and pilot studies for immune-PET imaging. 180N Autumn Webinar 2021 2021-10-01 - 2021-10-01 2021.
  • Lode, Kristin; Berzaghi, Rodrigo; Herranz Carnero, Michel; Hellevik, Turid; Martinez, Inigo Zubiavrre. Regulatory functions of cancer associated fibroblasts following radiation. Adaptation of the tumour ans its ecosystem to radiotherapies: Mechanisms, imaging and therapeutic approaches 2021-09-22 - 2021-09-25 2021.
  • Hellevik, Turid; Berzaghi, Rodrigo; Martinez, Inigo Zubiavrre; Lode, Kristin. Immuno-radiobiology of cancer-associated fibroblasts. BiGART2021 - Acta Oncologica Conference 2021-10-06 - 2021-10-06 2021.
  • Martinez, Inigo Zubiavrre; Hellevik, Turid. Radiobiology research in Northern-Norway. Norwegian BiGART2021 conference 2021-10-05 - 2021-10-05 2021.
  • Islam, Md Ashraful; Hellevik, Turid; Martinez, Inigo Zubiavrre. Immuno-PET imaging of the tumor-immune landscape using engineered antibody fragments. 180oN Autumn Webinar 2021 2021-10-01 - 2021-10-01 2021.
  • Martinez, Inigo Zubiavrre; Hellevik, Turid; Ringvold, Geir Hevnskjel. På labben: Slik sloss vi mot kreft. 2021.
  • Martinez, Inigo Zubiavrre; Hellevik, Turid. Immuno-PET tracers for lung cancer. 180oN Preclinical Workshop 2021-02-15 - 2021-02-15 2021.
  • Islam, Md Ashraful; Ploegh, Hidde L.; Hellevik, Turid; Martinez, Inigo Zubiavrre. Single-chain variable fragment (scFv) tracer development for immuno-PET imaging. 180oN Preclinical Workshop 2021-02-15 - 2021-02-15 2021.
  • Herranz Carnero, Michel; Hellevik, Turid; Martinez, Inigo Zubiavrre. Development of novel immuno-PET tracers for in vivo imaging of tumor-associated immunity.. 180oN Preclinical Workshop 2021-02-15 - 2021-02-15 2021.
  • Hellevik, Turid; Martinez, Inigo Zubiavrre. Immunoregulatory properties of irradiated fibroblasts. ESTRO-2020 Online Congress 2020-11-28 - 2020-11-28 2020.
  • Martinez, Inigo Zubiavrre; Hellevik, Turid. Immuno-PET technology in preclinical cancer models. Symposium 2019-02-20 - 2019-02-21 2019.
  • Berzaghi, Rodrigo; Akhtar, Muhammad Asad; Tornaas, Stian; Hellevik, Turid; Martinez, Inigo Zubiavrre. Impact of ionizing radiation on immunoregulatory roles of Cancer-Associated Fibroblasts. ESTRO 38 2019-04-26 - 2019-04-30 2019.
  • Hellevik, Turid; Martinez, Inigo Zubiavrre. Alternative biomarkører til Immunterapi. Tidsskrift for Den norske legeforening 2019; Volum 139 (14). ISSN 0029-2001.s doi: 10.4045/tidsskr.19.0454.
  • Hellevik, Turid; Martinez, Inigo Zubiavrre. Immuno-PET imaging in Radiotherapy & Immunotherapy research. Network in Radiation Oncology (NIRO) 2019-11-14 - 2019.
  • Martinez, Inigo Zubiavrre; Hellevik, Turid. Tumor fibroblasts in the radiotherapy context. Network in Radiation Oncology 2019-11-14 - 2019-11-14 2019.
  • Hellevik, Turid; Martinez, Inigo Zubiavrre. Potensialet til Immuno-PET avbildning for Immunoterapi og Stråleterapi. Foredrag 2019-10-31 - 2019-10-31 2019.
  • Bhandari, Sabin; Li, Ruomei; Kyrrestad, Ingelin; Bruun, Jack-Ansgar; Urbarova, Ilona; Smedsrød, Bård; Martinez, Inigo Zubiavrre; Simon-Santamaria, Jaione; Sørensen, Karen Kristine. Effect of glucocorticoids on liver sinusoidal endothelial cells in vitro. The 2019 Liver Sinusoidal Meeting: 20th International Symposium on Cells of the Hepatic Sinusoid 2019-09-04 - 2019-09-07 2019.
  • Bruvoll, Mathias; Martinez, Inigo Zubiavrre; Hellevik, Turid. UiT-forskere tildelt millioner fra Kreftforeningen. 2018.
  • Hellevik, Turid; Martinez, Inigo Zubiavrre. Strategier for kombinert Stråleterapi & Immunterapi. Fagdag 2018-01-08 - 2018-01-08 2018.
  • Hellevik, Turid; Martinez, Inigo Zubiavrre. Optimizing radiotherapy-Immunotherapy combinations in preclinical models. 4th Conference on small animal precision image-guided radiotherapy 2018-03-12 - 2018-03-14 2018.
  • Berzaghi, Rodrigo; Akhtar, Muhammad Asad; Tornaas, Stian; Hellevik, Turid; Martinez, Inigo Zubiavrre. Radiation abrogates CAF-mediated immunosuppressive effects on dendritic cells. 3rd International Conference on Immunotherapy Radiotherapy Combinations 2018-09-20 - 2018-09-22 2018.
  • Martinez, Inigo Zubiavrre. Role of fibroblasts in lung tumor responses to therapy. Seminar GENyO, Granada 2018-09-25 - 2018-09-25 2018.
  • Islam, Ashraful; Fossum, Vegard; Hansen, Ann Kristin; Urbarova, Ilona; Knutsen, Gunnar; Martinez, Inigo Zubiavrre. In vitro chondrogenic potency of surplus chondrocytes from ACI does not predict short-term clinical outcomes.. Norsk ortopedisk forenings Høstmøte 2018 2018-10-24 - 2018-10-26 2018.
  • Johansen, Per-Christian; Hellevik, Turid; Martinez, Inigo Zubiavrre. Millionstøtte til preklinisk kreftforskning. 2018.
  • Li, Ruomei; Simon-Santamaria, Jaione; Bhandari, Sabin; Bruun, Jack-Ansgar; Urbarova, Ilona; Smedsrød, Bård; Martinez, Inigo Zubiavrre; Sørensen, Karen Kristine. Phenotypic changes in rat liver sinusoidal endothelial cells during early stages of in vitro culture. 19th International Symposium of cells of the Hepatic Sinusoid 2017-06-14 - 2017-06-17 2017.
  • Hellevik, Turid; Grinde, Maria Tunset; Vik, Jørg; Camilio, Ketil Andre; Martinez, Inigo Zubiavrre. Ionizing radiation abrogates pro-tumorigenic effects from cancer-associated fibroblasts in xenografts. Cancer Research 2017; Volum 77 (13). ISSN 0008-5472.s doi: 10.1158/1538-7445.AM2017-5209.
  • Martinez, Inigo Zubiavrre; Hellevik, Turid. Tumor fibroblasts at the intersection of Radiotherapy and Immunotherapy. 2nd Intl Conference: Immunotherapy-Radiotherapy Combinations 2017-09-21 - 2017-09-23 2017.
  • Martinez, Inigo Zubiavrre; Hellevik, Turid. Kreftforskning ved Molekylær Inflammasjon Forskningsgruppe, IKM. Brukermedvirkning i Kreftforskning 2017-11-03 - 2017-11-03 2017.
  • Martinez, Inigo Zubiavrre; Hellevik, Turid. Kombinert Stråle-Immunterapi ved Lungekreft. Lungekreftdagen 2017 2017-11-09 - 2017-11-09 2017.
  • Bhandari, Sabin; Li, Ruomei; Simon-Santamaria, Jaione; McCourt, Peter Anthony; Johansen, Steinar Daae; Smedsrød, Bård; Martinez, Inigo Zubiavrre; Sørensen, Karen Kristine. The liver sinusoidal endothelial cell – an endothelial cell with a macrophage-like identity. 19th International Symposium of cells of the Hepatic Sinusoid, Galway, Ireland, June 14th-June 17th 2017-06-14 - 2017-06-17 2017.
  • Hansen, Ann Kristin; Figenschau, Yngve Anton; Martinez, Inigo Zubiavrre. Dynamic expression of VDR and 1­alpha­hydroxylase in differentiated and re­differentiated human articular chondrocytes. 13th ICRS World Congress 2016-09-24 - 2016-09-27 2016.
  • Hellevik, Turid; Grinde, Maria Tunset; Vik, Jørg; Camilio, Ketil Andre; Martinez, Inigo Zubiavrre. In vivo models to study the role of tumor stroma in radiotherapy outcomes. Third International Symposium on precision Image-guided Small Animal Radiotherapy Research 2016-03-21 - 2016-03-23 2016.
  • Simon-Santamaria, Jaione; Li, Ruomei; Bhandari, Sabin; Bruun, Jack-Ansgar; Smedsrød, Bård; Martinez, Inigo Zubiavrre; Sørensen, Karen Kristine. Secretome of the liver sinusoidal endothelial cell. The 52nd Norwegian Biochemical Society (NBS) Contact Meeting 2016-01-21 - 2016-01-23 2016.
  • Bhandari, Sabin; Li, Ruomei; Simon-Santamaria, Jaione; McCourt, Peter Anthony; Johansen, Steinar Daae; Smedsrød, Bård; Martinez, Inigo Zubiavrre; Sørensen, Karen Kristine. Next generation deep sequencing of rat liver sinusoidal endothelial cell and Kupffer cell transcriptomes suggests functional complementarity. The 52nd Norwegian Biochemical Society (NBS) Contact Meeting 2016-01-21 - 2016-01-23 2016.
  • Gorchs, Laia; Hellevik, Turid; Bruun, Jack-Ansgar; Camilio, Ketil Andre; Al-Saad, Samer; Stuge, Tor Brynjar; Martinez, Inigo Zubiavrre. Cancer-associated fibroblasts from lung tumors maintain their immunosuppressive abilities after high-dose irradiation. Cell Symposia: Cancer, Inflammation & Immunity 2015-06-14 - 2015-06-16 2015.
  • Gorchs, Laia; Hellevik, Turid; Bruun, Jack-Ansgar; Camilio, Ketil Andre; Al-Saad, Samer; Stuge, Tor Brynjar; Martinez, Inigo Zubiavrre. Immunoregulatory functions of Cancer-associated Fibroblasts from lung cancers. Cell Symposia: Cancer, Inflammation and immunity 2015-06-14 - 2015-06-16 2015.
  • Hellevik, Turid; Martinez, Inigo Zubiavrre. Research Topic: Radiobiological clues towards optimizing high-dose Radiotherapy. Frontiers in Oncology 2014; Volum 21 (4). ISSN 2234-943X.s doi: 10.3389/fonc.2014.00001.
  • Hellevik, Turid; Gorch, Laia; Stuge, Tor Brynjar; Martinez, Inigo Zubiavrre. High-dose irradiation does not modify the immunosuppressive effects elicited by cancer-associated fibroblasts. Anticancer Research 2014; Volum 34 (10). ISSN 0250-7005.s 5945 - 5945.
  • Gorch, Laia; Hellevik, Turid; Stuge, Tor Brynjar; Martinez, Inigo Zubiavrre. Immunomodulatory properties of Cancer-Associated Fibroblasts. Anticancer Research 2014; Volum 34 (10). ISSN 0250-7005.s 6050 - 6050.
  • Martinez, Inigo Zubiavrre; Gorch, Laia; Stuge, Tor Brynjar; Hellevik, Turid. Immuno-modulatory properties of cancer-associated Fibroblasts and its changes during radiotherapy. Immune and stromal responses in cancerology: new challenges for therapeutic targeting 2014-10-01 - 2014-10-04 2014.
  • Hansen, Ann Kristin; Indrevik, Jill-Tove; Figenschau, Yngve Anton; Martinez, Inigo Zubiavrre; Sveinbjørnsson, Baldur. Expression and function of Leukotriene B4 receptors in human articular chondrocytes. 11th ICRS World Congress 2013-09-15 - 2013-09-18 2013.
  • Hellevik, Turid; Martinez, Inigo Zubiavrre. Strålebiologisk forskning ved UNN/UiT. "Møt en forsker" 2013-09-26 - 2013.
  • Martinez, Inigo Zubiavrre; Pettersen, Ingvild; Hellevik, Turid. Cancer-associated fibroblasts from human NSCLC survive ablative doses of radiation but their invasive capacity is reduced. ICTR-PHE-12 2012-02-27 - 2012-03-02 2012.
  • Hellevik, Turid; Martinez, Inigo Zubiavrre. Respons på ablativ stråleterapi hos NSCLC-assosierte fibroblaster. Bestpractice Onkologi/Hematologi 2012 (9). ISSN 2245-0440.s 10 - 12.
  • Hellevik, Turid; Pettersen, ingvild; Winberg, Jan-Olof; Berg, Vivian; Bruun, Jack-Ansgar; Moe, Bjørn Thorvald Greve; Bartnes, Kristian; Busund, Lill-Tove; Chalmers, Anthony; Bremnes, Roy M.; Martinez, Inigo Zubiavrre. Consequential effects of ablative ionizing radiation on tumor stromal fibroblasts from lung tumors. Cell Symposia: Hallmarks of Cancer 2012-10-29 - 2012-10-31 2012.
  • Hellevik, Turid; Pettersen, ingvild; Winberg, Jan-Olof; Berg, Vivian; Bartnes, Kristian; Busund, Lill-Tove; Bremnes, Roy M.; Chalmers, Anthony; Martinez, Inigo Zubiavrre. Secretory profile of Cancer-Associated Fibroblasts after exposure to ablative radiation doses: Impact on angiogenesis and tumor growth. ICTR-PHE 2012 International Conference on Translational Research in Radiation Oncology 2012-02-27 - 2012-03-02 2012.
  • Hellevik, Turid; Pettersen, Ingvild; Martinez, Inigo Zubiavrre. Impact of radiotherapy on the tumor stroma: Responses of Cancer-associated fibroblasts to ablative radiation. Molecular and Clinical Aspects of Cancer - 2012 2012-04-16 - 2012-04-20 2012.
  • Hellevik, Turid; Pettersen, Inger; Winberg, Jan-Olof; Berg, Vivian; Paulssen, Ruth H; Bartnes, Kristian; Busund, Lill-Tove; Bremnes, Roy M.; Martinez, Inigo Zubiavrre. The Impact of Ionizing Radiation on the Motility and Matrix Remodelling Properties of Carcinoma-associated Fibroblasts. European Journal of Cancer 2011; Volum 47. ISSN 0959-8049.s S142 - S143.
  • Elvenes, Jan; Martinez, Inigo Zubiavrre; Bendiksen, signy; Johansen, oddmund. Morpho-functional characterization of human articular chondrocytes expanded under different cell culture conditions. ICRS-2007, Poland 2007-09-28 - 2007-10-02 2007.
  • Hellevik, Turid; Martinez, Inigo Zubiavrre; Mellman, Ira. Endosomal vesiculation involves dynamin I. Progress Report 1999-10-20 - 1999-10-20 1999.
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