Professor

Lill-Tove Rasmussen Busund

Professor/Consultant Pathologist Department of Medical Biology

77644641

+47 41579210

lill.tove.rasmussen.busund@uit.no

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Tromsø

MH L8.215 (Click for map directions)

Pre-diagnostic, diagnostic, prognostic, predictive and follow-up cancer biomarkers in blood and cancer tissue.

Leader Course 2.4 Musculoskeletal system, Medical school

Leader Translational Cancer Research

Researcher profile in Cristin

Scientific articles and book chapters
Other

Kilvær, Thomas Karsten; Paulsen, Erna-Elise; Andersen, Sigve; Rakaee, Mehrdad; Bremnes, Roy M.; Rasmussen Busund, Lill-Tove; Dønnem, Tom. Digitally quantified CD8+ cells: the best candidate marker for an immune cell score in non-small cell lung cancer?. Carcinogenesis 2020; Volum 41 (12). ISSN 0143-3334.s 1671 - 1681.s doi: 10.1093/carcin/bgaa105.

Lund, Eiliv; Holden, Marit; Thalabard, Jean-Christophe; Rasmussen Busund, Lill-Tove; Snapkov, Igor; Holden, Lars. Signals of Death - Post-Diagnostic Single Gene Expression Trajectories in Breast Cancer - A Proof of Concept. Universitetsforlaget 2020 ISBN 978-82-15-04119-3.s 141 - 162.s doi: 10.18261/9788215041193-2020-09.

Rasmussen Busund, Lill-Tove. Hypothesis of Carcinogenesis - The Atavistic Theory. Universitetsforlaget 2020 ISBN 978-82-15-04119-3.s 163 - 168.s doi: 10.18261/9788215041193-2020.

Rakaee, Mehrdad; Busund, Lill-Tove; Jamaly, Simin; Paulsen, Erna-Elise; Richardsen, Elin; Andersen, Sigve; Al-Saad, Samer; Bremnes, Roy M.; Dønnem, Tom; Kilvær, Thomas Karsten. Prognostic Value of Macrophage Phenotypes in Resectable Non–Small Cell Lung Cancer Assessed by Multiplex Immunohistochemistry. Neoplasia 2019; Volum 21 (3). ISSN 1522-8002.s 282 - 293.s doi: 10.1016/j.neo.2019.01.005.

Moi, Line; Braaten, Tonje; Al-Shibli, Khalid; Lund, Eiliv; Rasmussen Busund, Lill-Tove. Differential expression of the miR-17-92 cluster and miR-17 family in breast cancer according to tumor type; results from the Norwegian Women and Cancer (NOWAC) study. Journal of Translational Medicine 2019; Volum 17:334. ISSN 1479-5876.s 1 - 20.s doi: 10.1186/s12967-019-2086-x.

Richardsen, Elin; Andersen, Sigve; Al-Saad, Samer; Rakaee, Mehrdad; Nordby, Yngve; Pedersen, Mona Irene; Ness, Nora; Ingebriktsen, Lise Martine; Fassina, Ambrogio; Tasken, Kristin Austlid; Mills, Ian Geoffrey; Dønnem, Tom; Bremnes, Roy M.; Rasmussen Busund, Lill-Tove. Low expression of miR-424-3p is highly correlated with clinical failure in prostate cancer. Scientific Reports 2019; Volum 9 (10662). ISSN 2045-2322.s 1 - 10.s doi: 10.1038/s41598-019-47234-0.

Kilvær, Thomas Karsten; Rakaee, Mehrdad; Hellevik, Turid; Vik, Jørg; de Petris, Luigi; Dønnem, Tom; Strell, Carina; Østman, Arne; Rasmussen Busund, Lill-Tove; Martinez, Inigo Zubiavrre. Differential prognostic impact of platelet-derived growth factor receptor Expression in NSCLC. Scientific Reports 2019; Volum 9:10163. ISSN 2045-2322.s 1 - 11.s doi: 10.1038/s41598-019-46510-3.

Richardsen, Elin; Andersen, Sigve; Melbø-Jørgensen, Christian; Rakaee, Mehrdad; Ness, Nora; Al-Saad, Samer; Nordby, Yngve; Pedersen, Mona Irene; Dønnem, Tom; Bremnes, Roy M.; Rasmussen Busund, Lill-Tove. MicroRNA 141 is associated to outcome and aggressive tumor characteristics in prostate cancer. Scientific Reports 2019; Volum 93:386 (1). ISSN 2045-2322.s 1 - 9.s doi: 10.1038/s41598-018-36854-7.

Kilvær, Thomas Karsten; Rakaee, Mehrdad; Hellevik, Turid; Östman, Arne; Strell, Carina; Bremnes, Roy M.; Busund, Lill-Tove; Dønnem, Tom; Martinez, Inigo Zubiavrre. Tissue analyses reveal a potential immune-adjuvant function of FAP-1 positive fibroblasts in non-small cell lung cancer. PLOS ONE 2018; Volum 13 (2). ISSN 1932-6203.s doi: 10.1371/journal.pone.0192157.

Lund, Eiliv; Busund, Lill-Tove; Thalabard, Jean-Christophe. Rethinking the carcinogenesis of breast cancer: The theory of breast cancer as a child deficiency disease or a pseudo semi-allograft. Medical Hypotheses 2018; Volum 120. ISSN 0306-9877.s 76 - 80.s doi: 10.1016/j.mehy.2018.08.015.

Grindstad, Thea K.W.; Richardsen, Elin; Andersen, Sigve; Skjefstad, Kaja Konstanse; Rakaee, Mehrdad; Dønnem, Tom; Ness, Nora; Nordby, Yngve; Bremnes, Roy M.; Al-Saad, Samer; Busund, Lill-Tove. Progesterone receptors in prostate cancer: Progesterone receptor B is the isoform associated with disease progression. Scientific Reports 2018; Volum 8:11358. ISSN 2045-2322.s 1 - 10.s doi: 10.1038/s41598-018-29520-5.

Rakaee, Mehrdad; Kilvær, Thomas Karsten; Dalen, Stig Manfred; Richardsen, Elin; Paulsen, Erna Elise; Hald, Sigurd; Al-Saad, Samer; Andersen, Sigve; Dønnem, Tom; Bremnes, Roy M.; Busund, Lill-Tove. Evaluation of tumor-infiltrating lymphocytes using routine H&E slides predicts patient survival in resected non-small cell lung cancer. Human Pathology 2018; Volum 79. ISSN 0046-8177.s 188 - 198.s doi: 10.1016/j.humpath.2018.05.017.

Skjefstad, Kaja Konstanse; Johannessen, Charles; Grindstad, Thea K.W.; Kilvær, Thomas Karsten; Paulsen, Erna Elise; Pedersen, Mona Irene; Dønnem, Tom; Andersen, Sigve; Bremnes, Roy M.; Richardsen, Elin; Al-Saad, Samer; Busund, Lill-Tove. A gender specific improved survival related to stromal miR-143 and miR-145 expression in non-small cell lung cancer. Scientific Reports 2018; Volum 8. ISSN 2045-2322.s doi: 10.1038/s41598-018-26864-w.

Hald, Sigurd; Rakaee, Mehrdad; Martinez, Inigo Zubiavrre; Richardsen, Elin; Al-Saad, Samer; Paulsen, Erna Elise; Blix, Egil Støre; Kilvær, Thomas Karsten; Andersen, Sigve; Busund, Lill-Tove; Bremnes, Roy M.; Dønnem, Tom. LAG-3 in Non-Small-cell Lung Cancer: Expression in Primary Tumors and Metastatic Lymph Nodes Is Associated With Improved Survival. Clinical Lung Cancer 2018; Volum 19 (3). ISSN 1525-7304.s 249 - 259.e2.s doi: 10.1016/j.cllc.2017.12.001.

Kiselev, Yury; Andersen, Sigve; Johannessen, Charles; Fjukstad, Bjørn; Olsen, Karina Standahl; Stenvold, Helge; Al-Saad, Samer; Dønnem, Tom; Richardsen, Elin; Bremnes, Roy M.; Busund, Lill-Tove. Transcription factor PAX6 as a novel prognostic factor and putative tumour suppressor in non-small cell lung cancer. Scientific Reports 2018; Volum 8. ISSN 2045-2322.s doi: 10.1038/s41598-018-23417-z.

Nordby, Yngve; Richardsen, Elin; Rakaee, Mehrdad; Ness, Nora; Dønnem, Tom; Patel, Hitendra R.H.; Busund, Lill-Tove; Bremnes, Roy M.; Andersen, Sigve. High expression of PDGFR-β in prostate cancer stroma is independently associated with clinical and biochemical prostate cancer recurrence. Scientific Reports 2017; Volum 7:43378. ISSN 2045-2322.s 1 - 9.s doi: 10.1038/srep43378.

Richardsen, Elin; Andersen, Sigve; Al-Saad, Samer; Rakaee, Mehrdad; Nordby, Yngve; Pedersen, Mona Irene; Ness, Nora; Grindstad, Thea K.W.; Movik, Ingeborg; Dønnem, Tom; Bremnes, Roy M.; Busund, Lill-Tove. Evaluation of the proliferation marker Ki-67 in a large prostatectomy cohort. PLOS ONE 2017; Volum 12:e0186852 (11). ISSN 1932-6203.s 1 - 13.s doi: 10.1371/journal.pone.0186852.

Nordby, Yngve; Richardsen, Elin; Ness, Nora; Dønnem, Tom; Patel, Hitendra R.H.; Busund, Lill-Tove; Bremnes, Roy M.; Andersen, Sigve. High miR-205 expression in normal epithelium is associated with biochemical failure - An argument for epithelial crosstalk in prostate cancer?. Scientific Reports 2017; Volum 7:16308. ISSN 2045-2322.s 1 - 10.s doi: 10.1038/s41598-017-16556-2.

Andersen, Sigve; Richardsen, Elin; Rakaee, Mehrdad; Bertilsson, Helena; Bremnes, Roy M.; Børset, Magne; Busund, Lill-Tove; Slørdahl, Tobias Schmidt. Expression of phosphatase of regenerating liver (PRL)-3, is independently associated with biochemical failure, clinical failure and death in prostate cancer. PLOS ONE 2017; Volum 12 (11). ISSN 1932-6203.s doi: 10.1371/journal.pone.0189000.

Johannessen, Charles; Moi, Line; Kiselev, Yury; Pedersen, Mona Irene; Dalen, Stig Manfred; Braaten, Tonje; Busund, Lill-Tove. Expression and function of the miR-143/145 cluster in vitro and in vivo in human breast cancer. PLOS ONE 2017; Volum 12 (10). ISSN 1932-6203.s doi: 10.1371/journal.pone.0186658.

Paulsen, Erna-Elise; Kilvær, Thomas Karsten; Rakaee, Mehrdad; Richardsen, Elin; Hald, Sigurd; Andersen, Sigve; Busund, Lill-Tove; Bremnes, Roy M.; Dønnem, Tom. CTLA-4 expression in the non-small cell lung cancer patient tumor microenvironment: diverging prognostic impact in primary tumors and lymph node metastases. Cancer Immunology and Immunotherapy 2017; Volum 66. ISSN 0340-7004.s 1449 - 1461.s doi: 10.1007/s00262-017-2039-2.

Al-Saad, Samer; Richardsen, Elin; Kilvær, Thomas Karsten; Dønnem, Tom; Andersen, Sigve; Rakaee, Mehrdad; Bremnes, Roy M.; Busund, Lill-Tove. The impact of MET, IGF-1, IGF1R expression and EGFR mutations on survival of patients with non-small-cell lung cancer. PLOS ONE 2017; Volum 12:e0181527 (7). ISSN 1932-6203.s 1 - 20.s doi: 10.1371/journal.pone.0181527.

Duell, Eric J.; Lujan-Barroso, Leila; Sala, Núria; Deitz McElyea, Samantha; Overvad, Kim; Tjønneland, Anne; Olsen, Anja; Weiderpass, Elisabete; Busund, Lill-Tove; Moi, Line; Muller, David; Vineis, Paolo; Aune, Dagfinn; Matullo, Giuseppe; Naccarati, Alessio; Panico, Salavatore; Tagliabue, Giovanna; Tumino, Rosario; Palli, Domenico; Kaaks, Rudolf; Katzke, Verena A.; Boeing, Heiner; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Trichopoulou, Antonia; Lagiou, Pagona; Kotanidou, Anastasia; Travis, Ruth C.; Wareham, Nick; Khaw, Kay-Tee; Ramõn Quirõs, Jose; Rodríguez-Barranco, Miguel; Dorronsoro, Miren; Chirlaque, María Dolores; Ardanaz, Eva; Severi, Gianluca; Boutron-Ruault, Marie-Christine; Rebours, Vinciane; Brennan, Paul; Gunter, Marc; Scelo, Ghislaine; Cote, Greg; Sherman, Stuart; Korc, Murray. Plasma microRNAs as biomarkers of pancreatic cancer risk in a prospective cohort study. International Journal of Cancer 2017; Volum 141 (5). ISSN 0020-7136.s 905 - 915.s doi: 10.1002/ijc.30790.

Ness, Nora; Andersen, Sigve; Rakaee, Mehrdad; Nordbakken, Cecilie; Valkov, Andrey Yurjevich; Paulsen, Erna-Elise; Nordby, Yngve; Bremnes, Roy M.; Dønnem, Tom; Busund, Lill-Tove; Richardsen, Elin. The prognostic role of immune checkpoint markers programmed cell death protein 1 (PD-1) and programmed death ligand 1 (PD-L1) in a large, multicenter prostate cancer cohort. OncoTarget 2017; Volum 8 (16). ISSN 1949-2553.s 26789 - 26801.s doi: 10.18632/oncotarget.15817.

Helland, Åslaug; Brustugun, Odd Terje; Nakken, Sigve; Halvorsen, Ann Rita; Dønnem, Tom; Bremnes, Roy M.; Busund, Lill-Tove; Sun, Jinchang; Lorenz, Susanne; Solberg, Steinar; Jørgensen, Lars Hilmar; Vodak, Daniel; Myklebost, Ola; Hovig, Eivind; Meza, Leonardo Zepeda. High number of kinome-mutations in non-small cell lung cancer is associated with reduced immune response and poor relapse-free survival. International Journal of Cancer 2017; Volum 141 (1). ISSN 0020-7136.s 184 - 190.s doi: 10.1002/ijc.30726.

Dønnem, Tom; Kilvær, Thomas Karsten; Andersen, Sigve; Richardsen, Elin; Paulsen, Erna-Elise; Hald, Sigurd; Al-Saad, Samer; Brustugun, Odd Terje; Helland, Åslaug; Lund-Iversen, Marius; Solberg, Steinar; Grønberg, Bjørn Henning; Wahl, Sissel Gyrid Freim; Helgeland, Lars; Fløtten, Øystein; Pohl, M; Al-Shibli, Khalid; Sandanger, Torkjel M; Pezzella, Francesco; Busund, Lill-Tove; Bremnes, Roy M.. Strategies for clinical implementation of TNM-Immunoscore in resected nonsmall-cell lung cancer. Annals of Oncology 2016; Volum 27 (2). ISSN 0923-7534.s 225 - 232.s doi: 10.1093/annonc/mdv560.

Paulsen, Erna-Elise; Kilvær, Thomas Karsten; Rakaee, Mehrdad; Al-Saad, Samer; Hald, Sigurd; Andersen, Sigve; Richardsen, Elin; Ness, Nora; Busund, Lill-Tove; Bremnes, Roy M.; Dønnem, Tom. Assessing PDL-1 and PD-1 in non-small cell lung cancer: a novel immunoscore approach. Clinical Lung Cancer 2016; Volum 18 (2). ISSN 1525-7304.s 220 - 233.e8.s doi: 10.1016/j.cllc.2016.09.009.

Andersen, Sigve; Richardsen, Elin; Moi, Line; Dønnem, Tom; Nordby, Yngve; Ness, Nora; Eilertsen Holman, Marte; Bremnes, Roy M.; Busund, Lill-Tove. Fibroblast miR-210 overexpression is independently associated with clinical failure in Prostate Cancer – a multicenter (in situ hybridization)study. Scientific Reports 2016; Volum 6:36573. ISSN 2045-2322.s doi: 10.1038/srep36573.

Rakaee, Mehrdad; Busund, Lill-Tove; Paulsen, Erna-Elise; Richardsen, Elin; Al-Saad, Samer; Andersen, Sigve; Dønnem, Tom; Bremnes, Roy M.; Kilvær, Thomas Karsten. Prognostic effect of intratumoral neutrophils across histological subtypes of non-small cell lung cancer. OncoTarget 2016; Volum 7 (44). ISSN 1949-2553.s 72184 - 72196.s doi: 10.18632/oncotarget.12360.

Grindstad, Thea; Skjefstad, Kaja; Andersen, Sigve; Ness, Nora; Nordby, Yngve; Al-Saad, Samer; Fismen, Silje; Dønnem, Tom; Rakaee, Mehrdad; Busund, Lill-Tove; Bremnes, Roy M.; Richardsen, Elin. Estrogen receptors α and β and aromatase as independent predictors for prostate cancer outcome. Scientific Reports 2016; Volum 6. ISSN 2045-2322.s doi: 10.1038/srep33114.

Bremnes, Roy M.; Busund, Lill-Tove; Kilvær, Thomas Karsten; Andersen, Sigve; Richardsen, Elin; Paulsen, Erna-Elise; Hald, Sigurd; Rakaee, Mehrdad; Cooper, Wendy A.; Kao, Steven C.; Dønnem, Tom. The role of tumor-infiltrating lymphocytes in development, progression, and prognosis of non-small cell lung cancer. Journal of Thoracic Oncology 2016; Volum 11 (6). ISSN 1556-0864.s 789 - 800.s doi: 10.1016/j.jtho.2016.01.015.

Kilvær, Thomas Karsten; Paulsen, Erna-Elise; Rakaee, Mehrdad; Al-Saad, Samer; Johansen Maurseth, Ramona; Al-Shibli, Khalid; Bremnes, Roy M.; Busund, Lill-Tove; Dønnem, Tom. The presence of intraepithelial CD45RO+ cells in resected lymph nodes with metastases from NSCLC patients is an independent predictor of disease-specific survival. British Journal of Cancer 2016; Volum 114 (10). ISSN 0007-0920.s 1145 - 1151.s doi: 10.1038/bjc.2016.92.

Skjefstad, Kaja; Grindstad, Thea; Rakaee, Mehrdad; Richardsen, Elin; Dønnem, Tom; Kilvær, Thomas Karsten; Andersen, Sigve; Bremnes, Roy M.; Busund, Lill-Tove; Al-Saad, Samer. Prognostic relevance of estrogen receptor α, β and aromatase expression in non-small cell lung cancer. Steroids 2016; Volum 113. ISSN 0039-128X.s 5 - 13.s doi: 10.1016/j.steroids.2016.05.008.

Pøhl, Mette; Olsen, Karen Ege; Holst, Rene; Dønnem, Tom; Busund, Lill-Tove; Bremnes, Roy M.; Al-Saad, Samer; Andersen, Sigve; Richardsen, Elin; Ditzel, Henrik J; Hansen, Olfred. Keratin 34betaE12/keratin7 expression is a prognostic factor of cancer-specific and overall survival in patients with early stage non-small cell lung cancer. Acta Oncologica 2016; Volum 55 (2). ISSN 0284-186X.s 167 - 177.s doi: 10.3109/0284186X.2015.1049291.

Richardsen, Elin; Uglehus, Rebecca dale; Johnsen, Stein Harald; Busund, Lill-Tove. Macrophage-Colony Stimulating Factor (CSF1) Predicts Breast Cancer Progression and Mortality.. Anticancer Research 2015; Volum 35 (2). ISSN 0250-7005.s 865 - 874.

Richardsen, Elin; Busund, Lill-Tove. Prostate and Bladder Carcinomas: Histology, Immunohistochemistry, Genetic Biomarkers. Springer 2015 ISBN 978-1-4471-4257-7.s 79 - 91.s doi: 10.1007/978-1-4471-4258-4_9.

Nordby, Yngve; Andersen, Sigve; Richardsen, Elin; Ness, Nora; Al-Saad, Samer; Melbø-Jørgensen, Christian; Patel, Hitendra R.H.; Dønnem, Tom; Busund, Lill-Tove; Bremnes, Roy M.. Stromal expression of VEGF-A and VEGFR-2 in prostate tissue is associated with biochemical and clinical recurrence after radical prostatectomy. The Prostate 2015; Volum 75 (15). ISSN 0270-4137.s 1682 - 1693.s doi: 10.1002/pros.23048.

Richardsen, Elin; Ness, Nora; Melbø-Jørgensen, Christian; Johannessen, Charles; Grindstad, Thea; Nordbakken, Cecilie; Al-Saad, Samer; Andersen, Sigve; Dønnem, Tom; Nordby, Yngve; Bremnes, Roy M.; Busund, Lill-Tove. The Prognostic Significance of CXCL16 and Its Receptor C-X-C Chemokine Receptor 6 in Prostate Cancer. American Journal of Pathology 2015; Volum 185 (10). ISSN 0002-9440.s 2722 - 2730.s doi: 10.1016/j.ajpath.2015.06.013.

Kilvær, Thomas Karsten; Paulsen, Erna-Elise; Hald, Sigurd; Wilsgaard, Tom; Bremnes, Roy M.; Busund, Lill-Tove; Dønnem, Tom. Lymphangiogenic markers and their impact on nodal metastasis and survival in non-small cell lung cancer - A structured review with meta-analysis. PLOS ONE 2015; Volum 10:e0132481 (8). ISSN 1932-6203.s doi: 10.1371/journal.pone.0132481.

Paulsen, Erna-Elise; Kilvær, Thomas Karsten; Rakaeekhanehkenari, Mehrdad; Johansen Maurseth, Ramona; Al-Saad, Samer; Hald, Sigurd; Al-Shibli, Khalid; Andersen, Sigve; Richardsen, Elin; Busund, Lill-Tove; Bremnes, Roy M.; Dønnem, Tom. CD45RO+ memory T lymphocytes – a candidate marker for TNM-immunoscore in squamous non-small cell lung cancer. Neoplasia 2015; Volum 17 (11). ISSN 1522-8002.s 839 - 848.s doi: 10.1016/j.neo.2015.11.004.

Kilvær, Thomas Karsten; Rakaeekhanehkenari, Mehrdad; Hellevik, Turid; Al-Saad, Samer; Paulsen, Erna-Elise; Bremnes, Roy M.; Busund, Lill-Tove; Dønnem, Tom; Martinez, Inigo Zubiavrre. Cancer associated fibroblasts in stage I-IIIA NSCLC: Prognostic impact and their correlations with tumor molecular markers. PLOS ONE 2015; Volum 10:e0134965 (8). ISSN 1932-6203.s doi: 10.1371/journal.pone.0134965.

Andersen, Sigve; Solstad, Ørjan; Moi, Line Leonore Haugan; Dønnem, Tom; Eilertsen, Marte; Nordby, Yngve; Ness, Nora; Richardsen, Elin; Busund, Lill-Tove; Bremnes, Roy M.. Organized metabolic crime in prostate cancer: The coexpression of MCT1 in tumor and MCT4 in stroma is an independent prognosticator for biochemical failure. Urologic Oncology 2015; Volum 33 (8). ISSN 1078-1439.s 338.e9 - 338.e17.s doi: 10.1016/j.urolonc.2015.05.013.

Skjefstad, Kaja; Richardsen, Elin; Dønnem, Tom; Andersen, Sigve; Kiselev, Yury; Grindstad, Thea; Hald, Sigurd; Al-Shibli, Khalid; Bremnes, Roy M.; Busund, Lill-Tove; Al-Saad, Samer. The prognostic role of progesterone receptor expression in non-small cell lung cancer patients: Gender-related impacts and correlation with disease-specific survival. Steroids 2015; Volum 98. ISSN 0039-128X.s 29 - 36.s doi: 10.1016/j.steroids.2015.01.020.

Hald, Sigurd; Kiselev, Yury; Al-Saad, Samer; Richardsen, Elin; Johannessen, Charles; Eilertsen, Marte; Kilvær, Thomas Karsten; Al-Shibli, Khalid; Andersen, Sigve; Busund, Lill-Tove; Bremnes, Roy M.; Dønnem, Tom. Prognostic impact of CXCL16 and CXCR6 in non-small cell lung cancer: Combined high CXCL16 expression in tumor stroma and cancer cells yields improved survival. BMC Cancer 2015; Volum 15 (441). ISSN 1471-2407.s doi: 10.1186/s12885-015-1446-z.

Dønnem, Tom; Hald, Sigurd; Paulsen, Erna-Elise; Richardsen, Elin; Al-Saad, Samer; Kilvær, Thomas Karsten; Brustugun, Odd Terje; Helland, Åslaug; Lund-Iversen, Marius; Poehl, Mette; Olsen, Karen Ege; Ditzel, Henrik J.; Hansen, Olfred; Al-Shibli, Khalid; Kiselev, Yury; Sandanger, Torkjel M; Andersen, Sigve; Pezzella, Francesco; Bremnes, Roy M.; Busund, Lill-Tove. Stromal CD8+ T-cell density - A promising supplement to TNM staging in non-small cell lung cancer. Clinical Cancer Research 2015; Volum 21 (11). ISSN 1078-0432.s 2635 - 2643.s doi: 10.1158/1078-0432.CCR-14-1905.

Grindstad, Thea; Andersen, Sigve; Al-Saad, Samer; Dønnem, Tom; Kiselev, Yury; Melbø-Jørgensen, Christian; Skjefstad, Kaja; Busund, Lill-Tove; Bremnes, Roy M.; Richardsen, Elin. High progesterone receptor expression in prostate cancer is associated with clinical failure. PLOS ONE 2015; Volum 10:e0116691 (2). ISSN 1932-6203.s doi: 10.1371/journal.pone.0116691.

Fassina, Ambrogio; Cappellesso, Rocco; Simonato, Francesca; Siri, Maayan; Ventura, Laura; Tosato, Francesca; Busund, Lill-Tove; Pelizzo, Maria Rosa; Fassan, Matteo. A 4-MicroRNA signature can discriminate primary lymphomas from anaplastic carcinomas in thyroid cytology smears. Cancer Cytopathology 2014; Volum 122 (4). ISSN 1934-662X.s 274 - 281.s doi: 10.1002/cncy.21383.

Eilertsen, Marte; Andersen, Sigve; Al-Saad, Samer; Kiselev, Yury; Dønnem, Tom; Stenvold, Helge; Pettersen, Ingvild; Al-Shibli, Khalid; Richardsen, Elin; Busund, Lill-Tove; Bremnes, Roy M.. Monocarboxylate transporters 1-4 in NSCLC: MCT1 is an independent prognostic marker for survival. PLOS ONE 2014; Volum 9 (9). ISSN 1932-6203.s doi: 10.1371/journal.pone.0105038.

Melbø-Jørgensen, Christian Nordahl; Ness, Nora; Andersen, Sigve; Valkov, Andrey Yurjevich; Dønnem, Tom; Al-Saad, Samer; Kiselev, Yury; Berg, Thomas; Nordby, Yngve; Bremnes, Roy M.; Busund, Lill-Tove; Richardsen, Elin. Stromal expression of miR-21 predicts biochemical failure in prostate cancer patients with Gleason score 6. (fulltekst) PLOS ONE 2014; Volum 9:e113039 (11). ISSN 1932-6203.s doi: 10.1371/journal.pone.0113039.

Andersen, Sigve; Richardsen, Elin; Nordby, Yngve; Ness, Nora; Størkersen, Øystein; Al-Shibli, Khalid; Dønnem, Tom; Bertilsson, Helena; Busund, Lill-Tove; Angelsen, Anders; Bremnes, Roy M.. Disease-specific outcomes of Radical Prostatectomies in Northern Norway; A case for the impact of perineural infiltration and postoperative PSA-doubling time. BMC Urology 2014; Volum 14 (1). ISSN 1471-2490.s doi: 10.1186/1471-2490-14-49.

Ness, Nora; Andersen, Sigve; Valkov, Andrey Yurjevich; Nordby, Yngve; Dønnem, Tom; Al-Saad, Samer; Busund, Lill-Tove; Bremnes, Roy M.; Richardsen, Elin. Infiltration of CD8+ lymphocytes is an independent prognostic factor of biochemical failure-free survival in prostate cancer. The Prostate 2014; Volum 74 (14). ISSN 0270-4137.s 1452 - 1461.s doi: 10.1002/pros.22862.

Stenvold, Helge; Dønnem, Tom; Andersen, Sigve; Al-Saad, Samer; Busund, Lill-Tove; Bremnes, Roy M.. Stage and tissue-specific prognostic impact of miR-182 in NSCLC. BMC Cancer 2014; Volum 14:138. ISSN 1471-2407.s doi: 10.1186/1471-2407-14-138.

Stenvold, Helge; Dønnem, Tom; Andersen, Sigve; Al-Saad, Samer; Valkov, Andrey Yurjevich; Pedersen, Mona Irene; Busund, Lill-Tove; Bremnes, Roy M.. High tumor cell expression of microRNA-21 in node positive non-small cell lung cancer predicts a favorable clinical outcome. BMC Clinical Pathology 2014; Volum 14. ISSN 1472-6890.s doi: 10.1186/1472-6890-14-9.

Kilvær, Thomas Karsten; Smeland, Eivind; Valkov, Andrey Yurjevich; Sørbye, Sveinung Wergeland; Bremnes, Roy M.; Busund, Lill-Tove; Dønnem, Tom. The VEGF- and PDGF-family of angiogenic markers have prognostic impact in soft tissue sarcomas arising in the extremities and trunk. (fulltekst) BMC Clinical Pathology 2014; Volum 14:5. ISSN 1472-6890.s doi: 10.1186/1472-6890-14-5.

Eilertsen, Marte; Andersen, Sigve; Al-Saad, Samer; Richardsen, Elin; Stenvold, Helge; Hald, Sigurd; Al-Shibli, Khalid; Dønnem, Tom; Busund, Lill-Tove; Bremnes, Roy M.. Positive prognostic impact of miR-210 in non-small cell lung cancer. Lung Cancer 2014; Volum 83 (2). ISSN 0169-5002.s 272 - 278.s doi: 10.1016/j.lungcan.2013.11.005.

Hellevik, Turid; Pettersen, Ingvild; Berg, Vivian; Bruun, Jack-Ansgar; Bartnes, Kristian; Busund, Lill-Tove; Chalmers, Anthony; Bremnes, Roy M.; Martinez, Inigo Zubiavrre. Changes in the secretory profile of NSCLC-associated fibroblasts after ablative radiotherapy: Potential impact on angiogenesis and tumor growth. (fulltekst) Translational Oncology 2013; Volum 6 (1). ISSN 1944-7124.s 66 - 74.s doi: 10.1593/tlo.12349.

Hald, Sigurd; Bremnes, Roy M.; Al-Shibli, Khalid; Al-Saad, Samer; Andersen, Sigve; Stenvold, Helge; Busund, Lill-Tove; Dønnem, Tom. CD4/CD8 co-expression shows independent prognostic impact in resected non-small cell lung cancer patients treated with adjuvant radiotherapy. Lung Cancer 2013; Volum 80 (2). ISSN 0169-5002.s 209 - 215.s doi: 10.1016/j.lungcan.2012.12.026.

Simonato, Francesca; Ventura, Laura; Sartori, Nicola; Cappellesso, Rocco; Fassan, Matteo; Busund, Lill-Tove; Fassina, Ambrogio. Detection of MicroRNAs in Archival Cytology Urine Smears. PLOS ONE 2013; Volum 8 (2). ISSN 1932-6203.s doi: 10.1371/journal.pone.0057490.

Sørbye, Sveinung Wergeland; Kilvær, Thomas Karsten; Valkov, Andrey Yurjevich; Dønnem, Tom; Smeland, Eivind; Al-Shibli, Khalid; Bremnes, Roy M.; Busund, Lill-Tove. Prognostic impact of Skp2, ER and PGR in male and female patients with soft tissue sarcomas. (fulltekst) BMC Clinical Pathology 2013; Volum 13 (9). ISSN 1472-6890.s doi: 10.1186/1472-6890-13-9.

Stenvold, Helge; Dønnem, Tom; Andersen, Sigve; Al-Saad, Samer; Al-Shibli, Khalid Ibrahim; Busund, Lill-Tove; Bremnes, Roy M.. Overexpression of matrix metalloproteinase-7 and -9 in NSCLC tumor and stromal cells: Correlation with a favorable clinical outcome. Lung Cancer 2012; Volum 75 (2). ISSN 0169-5002.s 235 - 241.s doi: 10.1016/j.lungcan.2011.06.010.

Dønnem, Tom; Bremnes, Roy M.; Busund, Lill-Tove; Andersen, Sigve; Pezzella, F. Gene expression assays as prognostic and predictive markers in early stage non-small cell lung cancer. Journal of Thoracic Disease 2012; Volum 4 (2). ISSN 2072-1439.s 212 - 213.s doi: 10.3978/j.issn.2072-1439.2012.03.02.

Smeland, Eivind; Kilvær, Thomas Karsten; Sørbye, Sveinung Wergeland; Valkov, Andrey Yurjevich; Andersen, Sigve; Bremnes, Roy M.; Busund, Lill-Tove; Dønnem, Tom. Prognostic Impacts of Hypoxic Markers in Soft Tissue Sarcoma. Sarcoma 2012; Volum 2012. ISSN 1357-714X.s doi: 10.1155/2012/541650.

Eilertsen, Marte; Pettersen, ingvild; Andersen, Sigve; Martinez, Inigo Zubiavrre; Dønnem, Tom; Busund, Lill-Tove; Bremnes, Roy M.. In NSCLC, VEGF-A Response to Hypoxia May Differ between Squamous Cell and Adenocarcinoma Histology. (sammendrag) Anticancer Research 2012; Volum 32 (11). ISSN 0250-7005.s 4729 - 4736.

Sørbye, Sveinung Wergeland; Kilvær, Thomas Karsten; Valkov, Andrey Yurjevich; Dønnem, Tom; Smeland, Eivind; Al-Shibli, Khalid; Bremnes, Roy M.; Busund, Lill-Tove. Prognostic Impact of Jab1, p16, p21, p62, Ki67 and Skp2 in Soft Tissue Sarcomas. (fulltekst) PLOS ONE 2012; Volum 7 (10). ISSN 1932-6203.s doi: 10.1371/journal.pone.0047068.

Hellevik, Turid; Pettersen, ingvild; Berg, Vivian; Winberg, Jan-Olof; Moe, Bjørn Torvald Greve; Bartnes, Kristian; Paulssen, Ruth H; Busund, Lill-Tove; Bremnes, Roy M.; Chalmers, Antony; Martinez, Inigo Zubiavrre. Cancer-associated fibroblasts from human NSCLC survive ablative doses of radiation but their invasive capacity is reduced. Radiation Oncology 2012; Volum 7. ISSN 1748-717X.s doi: 10.1186/1748-717X-7-59.

Sørbye, Sveinung Wergeland; Kilvær, Thomas Karsten; Valkov, Andrey Yurjevich; Dønnem, Tom; Smeland, Eivind; Al-Shibli, Khalid Ibrahim; Bremnes, Roy M.; Busund, Lill-Tove. Prognostic impact of peritumoral lymphocyte infiltration in soft tissue sarcomas. (fulltekst) BMC Clinical Pathology 2012; Volum 12 (5). ISSN 1472-6890.s doi: 10.1186/1472-6890-12-5.

Sørbye, Sveinung Wergeland; Kilvær, Thomas Karsten; Valkov, Andrey Yurjevich; Dønnem, Tom; Smeland, Eivind; Al-Shibli, Khalid Ibrahim; Bremnes, Roy M.; Busund, Lill-Tove. Prognostic impact of CD57, CD68, M-CSF, CSF-1R, Ki67 and TGF-beta in soft tissue sarcomas. (fulltekst) BMC Clinical Pathology 2012; Volum 12 (7). ISSN 1472-6890.s doi: 10.1186/1472-6890-12-7.

Dønnem, Tom; Fenton, Christopher Graham; Lønvik, Kenneth; Berg, Thomas; Eklo, Katrine; Andersen, Sigve; Stenvold, Helge; Al-Shibli, Khalid Ibrahim; Al-Saad, Samer; Bremnes, Roy M.; Busund, Lill-Tove. MicroRNA Signatures in Tumor Tissue Related to Angiogenesis in Non-Small Cell Lung Cancer. PLOS ONE 2012; Volum 7 (1). ISSN 1932-6203.s doi: 10.1371/journal.pone.0029671.

Bremnes, Roy M.; Al-Shibli, Khalid Ibrahim; Dønnem, Tom; Sirera, Rafael; Al-Saad, Samer; Andersen, Sigve; Stenvold, Helge; Camps, Carlos; Busund, Lill-Tove Rasmussen. The Role of Tumor-Infiltrating Immune Cells and Chronic Inflammation at the Tumor Site on Cancer Development, Progression, and Prognosis Emphasis on Non-small Cell Lung Cancer. Journal of Thoracic Oncology 2011; Volum 6 (1). ISSN 1556-0864.s 209 - 217.s doi: 10.1097/JTO.0b013e3182037b76.

Bremnes, Roy M.; Al-Shibli, Khalid Ibrahim; Dønnem, Tom; Sirera, Rafael; Al-Saad, Samer; Andersen, Sigve; Stenvold, Helge; Camps, Carlos; Busund, Lill-Tove. The Role of Tumor-Infiltrating Immune Cells and Chronic Inflammation at the Tumor Site on Cancer Development, Progression, and Prognosis. Journal of Thoracic Oncology 2011; Volum 6 (4). ISSN 1556-0864.s 824 - 833.s doi: 10.1097/jto.0b013e3182037b76.

Valkov, Andrey Yurjevich; Kilvær, Thomas Karsten; Sørbye, Sveinung Wergeland; Dønnem, Tom; Smeland, Eivind; Bremnes, Roy M.; Busund, Lill-Tove. The prognostic impact of Akt isoforms, PI3K and PTEN related to female steroid hormone receptors in soft tissue sarcomas. Journal of Translational Medicine 2011; Volum 9:200. ISSN 1479-5876.s doi: 10.1186/1479-5876-9-200.

Andersen, Sigve; Dønnem, Tom; Stenvold, Helge; Al-Saad, Samer; Al-Shibli, Khalid Ibrahim; Busund, Lill-Tove; Bremnes, Roy M.. Overexpression of the HIF Hydroxylases PHD1, PHD2, PHD3 and FIH Are Individually and Collectively Unfavorable Prognosticators for NSCLC Survival. PLOS ONE 2011; Volum 6 (8). ISSN 1932-6203.s doi: 10.1371/journal.pone.0023847.

Kilvær, Thomas Karsten; Valkov, Andrey Yurjevich; Sørbye, Sveinung Wergeland; Smeland, Eivind; Bremnes, Roy M.; Busund, Lill-Tove; Dønnem, Tom. Fibroblast growth factor 2 orchestrates angiogenic networking in non-GIST STS patients. Journal of Translational Medicine 2011; Volum 9. ISSN 1479-5876.s doi: 10.1186/1479-5876-9-104.

Andersen, Sigve; Dønnem, Tom; Al-Saad, Samer; Al-Shibli, Khalid Ibrahim; Stenvold, Helge; Busund, Lill-Tove; Bremnes, Roy M.. Correlation and Coexpression of HIFs and NOTCH Markers in NSCLC. Anticancer Research 2011; Volum 31 (5). ISSN 0250-7005.s 1603 - 1606.

Sørbye, Sveinung Wergeland; Kilvær, Thomas Karsten; Valkov, Andrey Yurjevich; Dønnem, Tom; Smeland, Eivind; Al-Shibli, Khalid Ibrahim; Bremnes, Roy M.; Busund, Lill-Tove. Prognostic Impact of Lymphocytes in Soft Tissue Sarcomas. PLOS ONE 2011; Volum 6 (1). ISSN 1932-6203.s doi: 10.1371/journal.pone.0014611.

Andersen, Sigve; Dønnem, Tom; Al-Shibli, Khalid Ibrahim; Al-Saad, Samer; Stenvold, Helge; Busund, Lill-Tove; Bremnes, Roy M.. Prognostic Impacts of Angiopoietins in NSCLC Tumor Cells and Stroma: VEGF-A Impact Is Strongly Associated with Ang-2. PLOS ONE 2011; Volum 6 (5). ISSN 1932-6203.s doi: 10.1371/journal.pone.0019773.

Dønnem, Tom; Andersen, Sigve; Al-Saad, Samer; Al-Shibli, Khalid Ibrahim; Busund, Lill-Tove; Bremnes, Roy M.. Prognostic Impact of Angiogenic Markers in Non-Small-Cell Lung Cancer is Related to Tumor Size. Clinical Lung Cancer 2011; Volum 12 (2). ISSN 1525-7304.s 106 - 115.s doi: 10.1016/j.cllc.2011.03.005.

Dønnem, Tom; Lønvik, Kenneth; Eklo, Katrine; Berg, Thomas; Sørbye, Sveinung Wergeland; Al-Shibli, Khalid Ibrahim; Al-Saad, Samer; Andersen, Sigve; Stenvold, Helge; Bremnes, Roy M.; Busund, Lill-Tove. Independent and Tissue-Specific Prognostic Impact of miR-126 in Nonsmall Cell Lung Cancer. Cancer 2011; Volum 117 (14). ISSN 0008-543X.s 3193 - 3200.s doi: 10.1002/cncr.25907.

Valkov, Andrey Yurjevich; Sørbye, Sveinung Wergeland; Kilvær, Thomas Karsten; Dønnem, Tom; Smeland, Eivind; Bremnes, Roy M.; Busund, Lill-Tove. Estrogen receptor and progesterone receptor are prognostic factors in soft tissue sarcomas. International Journal of Oncology 2011; Volum 38 (4). ISSN 1019-6439.s 1031 - 1040.s doi: 10.3892/ijo.2011.920.

Andersen, Sigve; Eilertsen, Marte; Dønnem, Tom; Al-Shibli, Khalid Ibrahim; Al-Saad, Samer; Busund, Lill-Tove; Bremnes, Roy M.. Diverging prognostic impacts of hypoxic markers according to NSCLC histology. Lung Cancer 2011; Volum 72 (3). ISSN 0169-5002.s 294 - 302.s doi: 10.1016/j.lungcan.2010.10.006.

Valkov, Andrey Yurjevich; Sørbye, Sveinung Wergeland; Kilvær, Thomas Karsten; Dønnem, Tom; Smeland, Eivind; Bremnes, Roy M.; Busund, Lill-Tove. The Prognostic Impact of TGF-beta 1, Fascin, NF-kappa B and PKC-zeta Expression in Soft Tissue Sarcomas. PLOS ONE 2011; Volum 6 (3). ISSN 1932-6203.s doi: 10.1371/journal.pone.0017507.

Dønnem, Tom; Eklo, Katrine; Berg, Thomas; Sørbye, Sveinung Wergeland; Lønvik, Kenneth; Al-Saad, Samer; Al-Shibli, Khalid Ibrahim; Andersen, Sigve; Stenvold, Helge; Bremnes, Roy M.; Busund, Lill-Tove. Prognostic Impact of MiR-155 in Non-Small Cell Lung Cancer Evaluated by in Situ Hybridization. Journal of Translational Medicine 2011; Volum 9. ISSN 1479-5876.s doi: 10.1186/1479-5876-9-6.

Berdal, Margrete; Appelbom, Hege; Eikrem, Jorunn H.; Lund, Åse; Busund, Lill-Tove; Hanes, Robert; Seljelid, Rolf; Jenssen, Trond. Aminated beta-1,3-D-glucan has a dose-dependent effect on wound healing in diabetic db/db mice. Wound Repair and Regeneration 2011; Volum 19 (5). ISSN 1067-1927.s 579 - 587.s doi: 10.1111/j.1524-475X.2011.00715.x.

Bremnes, Roy M.; Dønnem, Tom; Al-Saad, Samer; Al-Shibli, Khalid Ibrahim; Andersen, Sigve; Sirera, Rafael; Camps, Carlos; Martinez, Inigo Zubiavrre; Busund, Lill-Tove Rasmussen. The Role of Tumor Stroma in Cancer Progression and Prognosis Emphasis on Carcinoma-Associated Fibroblasts and Non-small Cell Lung Cancer. Journal of Thoracic Oncology 2011; Volum 6 (1). ISSN 1556-0864.s 209 - 217.s doi: 10.1097/JTO.0b013e3181f8a1bd.

Dønnem, Tom; Al-Shibli, Khalid Ibrahim; Andersen, Sigve; Al-Saad, Samer; Busund, Lill-Tove Rasmussen; Bremnes, Roy M.. Combination of low vascular endothelial growth factor A (VEGF-A)/VEGF receptor 2 expression and high lymphocyte infiltration is a strong and independent favorable prognostic factor in patients with nonsmall cell lung cancer. Cancer 2010; Volum 116. ISSN 0008-543X.s 4318 - 4325.s doi: 10.1002/cncr.25333.

Kilvær, Thomas Karsten; Valkov, Andrey Yurjevich; Sørbye, Sveinung Wergeland; Dønnem, Tom; Smeland, Eivind; Bremnes, Roy M.; Busund, Lill-Tove. Platelet-Derived Growth Factors in Non-GIST Soft-Tissue Sarcomas Identify a Subgroup of Patients with Wide Resection Margins and Poor Disease-Specific Survival. Sarcoma 2010. ISSN 1357-714X.s doi: 10.1155/2010/751304.

Kilvær, Thomas Karsten; Valkov, Andrey Yurjevich; Sørbye, Sveinung Wergeland; Smeland, Eivind; Bremnes, Roy M.; Busund, Lill-Tove Rasmussen; Dønnem, Tom. Profiling of VEGFs and VEGFRs as prognostic factors in soft tissue sarcoma: VEGFR-3 is an independent predictor of poor prognosis. PLOS ONE 2010; Volum 5 (12). ISSN 1932-6203.s doi: 10.1371/journal.pone.0015368.

Dønnem, Tom; Andersen, Sigve; Al-Shibli, Khalid Ibrahim; Al-Saad, Samer; Busund, Lill-Tove Rasmussen; Bremnes, Roy M.. Prognostic Impact of Notch Ligands and Receptors in Nonsmall Cell Lung Cancer Coexpression of Notch-1 and Vascular Endothelial Growth Factor-A Predicts Poor Survival. Cancer 2010; Volum 116 (24). ISSN 0008-543X.s 5676 - 5685.s doi: 10.1002/cncr.25551.

Al-Saad, Samer; Al-Shibli, Khalid; Dønnem, Tom; Andersen, Sigve; Bremnes, Roy M.; Busund, Lill-Tove Rasmussen. Clinical Significance of Epidermal Growth Factor Receptors in Non-small Cell Lung Cancer and a Prognostic Role for HER2 Gene Copy Number in Female Patients. Journal of Thoracic Oncology 2010; Volum 5 (10). ISSN 1556-0864.s 1536 - 1543.s doi: 10.1097/JTO.0b013e3181ea510a.

Richardsen, Elin; Uglehus, Rebecca Dale; Due, Jan; Busch, Christer; Busund, Lill-Tove Rasmussen. COX-2 is overexpressed in primary prostate cancer with metastatic potential and may predict survival. A comparison study between COX-2, TGF-beta, IL-10 and Ki67. Cancer Detection and Prevention 2010; Volum 34 (3). ISSN 0361-090X.s 316 - 322.s doi: 10.1016/j.canep.2010.03.019.

Dønnem, Tom; Al-Saad, Samer; Al-Shibli, Khalid Ibrahim; Busund, Lill-Tove Rasmussen; Bremnes, Roy M.. Co-expression of PDGF-B and VEGFR-3 strongly correlates with lymph node metastasis and poor survival in non-small-cell lung cancer. Annals of Oncology 2010; Volum 21 (2). ISSN 0923-7534.s 223 - 231.s doi: 10.1093/annonc/mdp296.

Al-Shibli, Khalid Ibrahim; Al-Saad, Samer; Andersen, Sigve; Dønnem, Tom; Bremnes, Roy M.; Busund, Lill-Tove Rasmussen. The prognostic value of intraepithelial and stromal CD3-, CD117-and CD138-positive cells in non-small cell lung carcinoma. APMIS - Journal of Pathologiy, Microbiology and Immunology 2010; Volum 118 (5). ISSN 0903-4641.s 371 - 382.s doi: 10.1111/j.1600-0463.2010.02609.x.

Dønnem, Tom; Al-Shibli, Khalid Ibrahim; Al-Saad, Samer; Delghandi, Marit Pedersen; Busund, Lill-Tove Rasmussen; Bremnes, Roy M.. VEGF-A and VEGFR-3 correlate with nodal status in operable non-small cell lung cancer: Inverse correlation between expression in tumor and stromal cells. Lung Cancer 2009; Volum 63 (2). ISSN 0169-5002.s 277 - 283.s doi: 10.1016/j.lungcan.2008.05.022.

Andersen, Sigve; Dønnem, Tom; Al-Saad, Samer; Al-Shibli, Khalid Ibrahim; Busund, Lill-Tove Rasmussen; Bremnes, Roy M.. Angiogenic Markers Show High Prognostic Impact on Survival in Marginally Operable Non-small Cell Lung Cancer Patients Treated with Adjuvant Radiotherapy. Journal of Thoracic Oncology 2009; Volum 4 (4). ISSN 1556-0864.s 463 - 471.

Dønnem, Tom; Al-Shibli, Khalid Ibrahim; Al-Saad, Samer; Busund, Lill-Tove Rasmussen; Bremnes, Roy M.. Prognostic Impact of Fibroblast Growth Factor 2 in Non-small Cell Lung Cancer Coexpression with VEGFR-3 and PDGF-B Predicts Poor Survival. Journal of Thoracic Oncology 2009; Volum 4 (5). ISSN 1556-0864.s 578 - 585.

Al-Shibli, Khalid Ibrahim; Al-Saad, Samer; Dønnem, Tom; Persson, Magnus L.; Bremnes, Roy M.; Busund, Lill-Tove Rasmussen. The prognostic value of intraepithelial and stromal innate immune system cells in non-small cell lung carcinoma. Histopathology 2009; Volum 55 (3). ISSN 0309-0167.s 301 - 312.s doi: 10.1111/j.1365-2559.2009.03379.x.

Al-Saad, Samer; Dønnem, Tom; Al-Shibli, Khalid Ibrahim; Persson, Magnus L.; Bremnes, Roy M.; Busund, Lill-Tove Rasmussen. Diverse prognostic roles of Akt isoforms, PTEN and PI3K in tumor epithelial cells and stromal compartment in non-small cell lung cancer. Anticancer Research 2009; Volum 29. ISSN 0250-7005.s 4175 - 4183.

Berg, thomas; Kalsaas, Ann Hilde; Büchner, Jochen; Busund, Lill-Tove Rasmussen. Ewing sarcoma-peripheral neuroectodermal tumor of the kidney with a FUS-ERG fusion transcript. Cancer Genetics and Cytogenetics 2009; Volum 194 (1). ISSN 0165-4608.s 53 - 57.s doi: 10.1016/j.cancergencyto.2009.06.002.

Richardsen, Elin; Sørbye, Sveinung Wergeland; Crowe, John Phil; Yang, Jia-Lin; Busund, Lill-Tove Rasmussen. Expression of M-CSF and CSF-1R Is Correlated with Histological Grade in Soft Tissue Tumors. Anticancer Research 2009; Volum 29 (10). ISSN 0250-7005.s 3861 - 3866.

Al-Shibli, Khalid Ibrahim; Dønnem, Tom; Al-Saad, Samer; Persson, Magnus L.; Bremnes, Roy M.; Busund, Lill-Tove Rasmussen. Prognostic effect of epithelial and stromal lymphocyte infiltration in non-small cell lung cancer. Clinical Cancer Research 2008; Volum 14. ISSN 1078-0432.s 5220 - 5227.s doi: 10.1158/1078-0432.CCR-08-0133.

Richardsen, Elin; Uglehus, Rebecca dale; Due, Jan; Busch, Christer; Busund, Lill-Tove Rasmussen. The prognostic impact of M-CSF, CSF-1 receptor, CD68 and CD3 in prostatic carcinoma. Histopathology 2008; Volum 53. ISSN 0309-0167.s 30 - 38.s doi: 10.1111/j.1365-2559.2008.03058.x.

Al-Saad, Samer; Al-Shibli, Khalid Ibrahim; Dønnem, Tom; Persson, Magnus L.; Bremnes, Roy M.; Busund, Lill-Tove Rasmussen. The prognostic impact of NF-kappa B p105, vimentin, E-cadherin and Par6 expression in epithelial and stromal compartment in non-small-cell lung cancer. British Journal of Cancer 2008; Volum 99 (9). ISSN 0007-0920.s 1476 - 1483.s doi: 10.1038/sj.bjc.6604713.

Dønnem, Tom; Al-Saad, Samer; Al-Shibli, Khalid Ibrahim; Andersen, Sigve; Busund, Lill-Tove Rasmussen; Bremnes, Roy M.. Prognostic impact of platelet-derived growth factors in non-small cell lung cancer tumor and stromal cells. Journal of Thoracic Oncology 2008; Volum 3 (9). ISSN 1556-0864.s 963 - 970.

Dønnem, Tom; Al-Saad, Samer; Al-Shibli, Khalid Ibrahim; Andersen, Sigve; Busund, Lill-Tove Rasmussen; Bremnes, Roy M.. Prognostic impact of platelet-derived growth facors in non-small cell lung cancer tumor and stromal cells. Journal of Thoracic Oncology 2008; Volum 3. ISSN 1556-0864.s 963 - 970.

Dønnem, Tom; Al-Saad, Samer; Al-Shibli, Khalid Ibrahim Mahdi; Delghandi, Marit Pedersen; Persson, Magnus L.; Nilsen, Marit Nina; Busund, Lill-Tove Rasmussen; Bremnes, Roy M.. Inverse prognostic impact of angiogenic marker expression in tumor cells versus stromal cells in non-small cell lung cancer. Clinical Cancer Research 2007; Volum 13. ISSN 1078-0432.s 6649 - 6657.s doi: 10.1158/1078-0432.CCR-07-0414.

Dønnem, Tom; Al-Saad, Samer; Al-Shibli, Khalid Ibrahim Mahdi; Delghandi, Marit Pedersen; Persson, Magnus L.; Nilsen, Marit Nina; Busund, Lill-Tove Rasmussen; Bremnes, Roy M.. Inverse prognostic impact of vascular endothelial growth factors (VEGFs) A,C,D and vascular growth factors receptors (VEGFRs) 1,2 and 3 in both neoplastic cell compartment and stromal compartment of non-small cell lung cancer (NSCLC) tissue. Clinical Cancer Research 2007; Volum 13 (22). ISSN 1078-0432.s 6649 - 6657.

Berdal, Margrete; Appelbom, Hege; Eikrem, Jorunn; Lund, Åse; Zykova, Svetlana; Busund, Lill-Tove Rasmussen; Seljelid, Rolf; Jenssen, Trond Geir. Aminated beta-1,3-D-glucan improves wound healing in diabetic db/db mice. Wound Repair and Regeneration 2007; Volum 15. ISSN 1067-1927.s 825 - 832.s doi: 10.1111/j.1524-475X.2007.00286.x.

Busund, Lill-Tove Rasmussen; Richardsen, Elin; Busund, Rolf; Ukkonen, Tanja; Bjørnsen, Tone; Busch, Christer; Stalsberg, Helge. Significant expression of IGFBP2 in breast cancer compared with benign lesions. Journal of Clinical Pathology 2005; Volum 58. ISSN 0021-9746.

Brandal, P; Busund, Lill-Tove Rasmussen; Heim, S. Genomic Abnormalities in Juxtaglomerular Cell Tumors. Cancer 2005; Volum 104. ISSN 0008-543X.s 504 - 510.

Brandal, P; Busund, Lill-Tove Rasmussen; Heim, S. Chromosome abnormalities in juxtaglomerular cell tumors. Cancer 2005; Volum 104. ISSN 0008-543X.s 504 - 510.

Busund, Lill-Tove Rasmussen; Killie, Mette K.; Bartnes, Kristian; Seljelid, Rolf. Spontaneously formed tumorigenic hybrids of meth a sarcoma and macrophages in vivo. International Journal of Cancer 2003; Volum 106. ISSN 0020-7136.s 153 - 159.

Busund, Lill-Tove Rasmussen; Killie, MK; Bartnes, Kristian; Seljelid, Rolf. Spontaneously formed tumorigenic hybrids of Meth A sarcoma cells and macrophages in vivo. International Journal of Cancer 2003; Volum 106. ISSN 0020-7136.s 153 - 9.

Busund, Lill-Tove Rasmussen; Killie, MK; Bartnes, Kristian; Olsen, Randi; Seljelid, Rolf. Spontaneous formed tumorigenic hybrids of Math A sarcoma and macrophages grow faster and are better vascularized than the parenteral tumor. International Journal of Cancer 2002; Volum 100. ISSN 0020-7136.s 407 - 13.

Busund, Lill-Tove Rasmussen; Killie, MK; Bartnes, Kristian; Olsen, Randi; Seljelid, Rolf. Spontaneous hybridization of macrophages and Meth A sarcoma cells. International Journal of Cancer 2002; Volum 98. ISSN 0020-7136.s 573 - 81.

Lassen, K; Jacobsen, E; Busund, Lill-Tove Rasmussen; Kjæve, Jørn. Luft i portvenen og nekrose av ventrikkelen. Tidsskrift for Den norske legeforening 2001; Volum 121. ISSN 0029-2001.s 181 - 183.

Busund, Lill-Tove; Killie, Mette Kjær; Leon, F; Bartnes, Kristian. Differential Expression of Major Histocompatibility Complex Class II Variants in Cells Infiltrating the Meth A Sarcoma. Scandinavian Journal of Immunology 1999; Volum 49. ISSN 0300-9475.s 501 - 505.s doi: 10.1046/j.1365-3083.1999.00530.x.

Konopski, Z; Busund, Lill-Tove; Seljelid, rolf; Eskeland, Trond. Phagocytosis of β-1,3-D-Glucan-Derivatized Microbeads by Mouse Peritoneal Macrophages Involves Three Different Receptors. Scandinavian Journal of Immunology 1991; Volum 33. ISSN 0300-9475.s 297 - 306.s doi: 10.1111/j.1365-3083.1991.tb01775.x.

Doita, M; Busund, Lill-Tove; Seljelid, rolf; Lipsky, PE. Effect of soluble aminated beta-1,3-D-polyglucose on human monocytes: stimulation of cytokine and prostaglandin E2 production but not antigen-presenting function. Journal of Leukocyte Biology 1991; Volum 49. ISSN 0741-5400.s 342 - 351.

Busund, Rolf; Lindsetmo, Rolv-Ole; Busund, Lill-Tove; Røkke, O.; Rekvig, Ole Petter; Revhaug, Arthur. Tumor Necrosis Factor and Interleukin 1 Appearance in Experimental Gram-negative Septic Shock: The Effects of Plasma Exchange With Albumin and Plasma Infusion. Archives of surgery (Chicago. 1960) 1991; Volum 126. ISSN 0004-0010.s 591 - 597.

Busund, Lill-Tove; Seljelid, rolf. Novel immunomodulators with pronounced in vivo effects caused by stimulation of cytokine release. Journal of Cellular Biochemistry 1991; Volum 46. ISSN 0730-2312.s 60 - 68.s doi: 10.1002/jcb.240460110.

Busund, Lill-Tove; Seljelid, rolf. Dynamics of Blood Components and Peritoneal Fluid during Treatment of Murine E. coli Sepsis with β-1, 3-D-Polyglucose Derivatives. Scandinavian Journal of Immunology 1990; Volum 32. ISSN 0300-9475.s 321 - 331.s doi: 10.1111/j.1365-3083.1990.tb02926.x.

Busund, Lill-Tove; Fandrem, J; Seljelid, rolf. Dynamics of Blood Components and Peritoneal Fluid during Treatment of Murine E. coli Sepsis with β-1,3-D-polyglucose Derivatives. II. Interleukin 1, Tumour Necrosis Factor. Prostaglandin E2, and Leukotriene B4. Scandinavian Journal of Immunology 1990; Volum 32. ISSN 0300-9475.s 333 - 340.s doi: 10.1111/j.1365-3083.1990.tb02927.x.

Busund, Lill-Tove; Seljelid, rolf. The Modulatory Effect of Lipoproteins on the Release of Interleukin 1 by Human Peritoneal Macrophages Stimulated with β-1,3-d-Polyglucose Derivatives. Scandinavian Journal of Immunology 1989; Volum 29. ISSN 0300-9475.s 477 - 484.s doi: 10.1111/j.1365-3083.1989.tb01147.x.

Seljelid, rolf; Figenschau, Yngve; Bøgwald, Jarl; Busund, Lill-Tove; Austgulen, R. Evidence that Tumour Necrosis Induced by Aminated β1-3D Polyglucose is Mediated by a Concerted Action of Local and Systemic Cytokines. Scandinavian Journal of Immunology 1989; Volum 30. ISSN 0300-9475.s 687 - 694.s doi: 10.1111/j.1365-3083.1989.tb02477.x.

Seljelid, rolf; Busund, Lill-Tove; Larm, O; Hoffman, J. The Protective Effect of β1–3D-Glucan-Derivatized Plastic Beads against Escherichia coli Infection in Mice. Scandinavian Journal of Immunology 1987; Volum 25. ISSN 0300-9475.s 55 - 60.s doi: 10.1111/j.1365-3083.1987.tb01046.x.

Busund, Lill-Tove; Upsky, P; Seljelid, rolf. Production of Prostaglandin E2 and Interleukin 1 by Mouse Peritoneal Macrophages Stimulated with β-l, 3-D-Glucan Derivatized Plastic Beads. Scandinavian Journal of Immunology 1987; Volum 26. ISSN 0300-9475.s 731 - 736.s doi: 10.1111/j.1365-3083.1987.tb02310.x.

Seljelid, rolf; Bøgwald, Jarl; Busund, Lill-Tove; Larm, O; Hoffman, J; Berge, A; Ugelstad, J.. In Vivo Activation of Mouse Macrophages with β-l,3-D-Glucan-Derivatized Plastic Beads. Scandinavian Journal of Immunology 1985; Volum 21. ISSN 0300-9475.s 601 - 605.s doi: 10.1111/j.1365-3083.1985.tb01850.x.

Skjefstad, Kaja Konstanse; Grindstad, Thea K.W.; Rakaee, Mehrdad; Richardsen, Elin; Dønnem, Tom; Kilvær, Thomas Karsten; Andersen, Sigve; Bremnes, Roy M.; Busund, Lill-Tove; Al-Saad, Samer. Corrigendum to "Prognostic relevance of estrogen receptor α, β and aromatase expression in non-small cell lung cancer" [Steroids 113 (2016) 5-13]. Steroids 2018; Volum 130. ISSN 0039-128X.s 36 - 37.s doi: 10.1016/j.steroids.2017.11.010.

Bremnes, Roy M.; Dønnem, Tom; Busund, Lill-Tove. Importance of tumor infiltrating lymphocytes in non-small cell lung cancer?. Annals of Translational Medicine 2016; Volum 4 (7). ISSN 2305-5839.s doi: 10.21037/atm.2016.03.28.

Moi, Line Leonore Haugan; Lund, Eiliv; Busund, Lill-Tove. MicroRNAs in the Norwegian Women and Cancer study - the search for improved prognostic markers in breast cancer. Årsmøte Den norske patologforening 2015-03-19 - 2015-03-20 2015.

Kiselev, Yury; Valkov, Andrey Yurjevich; Busund, Lill-Tove; Bremnes, Roy M.; Snapkov, Igor; Mikkola, Ingvild; Kilvær, Thomas Karsten; Sorbye, SW; Smeland, Eivind; Dønnem, Tom. Transcription factor PAX6 is expressed in human soft tissue sarcomas and confers negative impact on patients' survival. American Association of Cancer Research Annual Conference 2014-04-06 - 2014-04-07 2014.

Dønnem, Tom; Bremnes, Roy M.; Lund, Eiliv; Busund, Lill-Tove. Personlig tilpasset kreftbehandling. Nordlys 2014. ISSN 0805-5440.

Andersen, Sigve; Eggen, Tormod; Dønnem, Tom; Busund, Lill-Tove; Bremnes, Roy M.. Sudden Death by an Atrial-Esophageal Fistulae. Journal of Thoracic Oncology 2013; Volum 8 (2). ISSN 1556-0864.s 254 - 254.s doi: 10.1097/JTO.0b013e31827ce3a9.

Hellevik, Turid; Pettersen, ingvild; Winberg, Jan-Olof; Berg, Vivian; Bartnes, Kristian; Busund, Lill-Tove; Bremnes, Roy M.; Chalmers, Anthony; Martinez, Inigo Zubiavrre. Secretory profile of Cancer-Associated Fibroblasts after exposure to ablative radiation doses: Impact on angiogenesis and tumor growth. ICTR-PHE 2012 International Conference on Translational Research in Radiation Oncology 2012-02-27 - 2012-03-02 2012.

Hellevik, Turid; Pettersen, ingvild; Winberg, Jan-Olof; Berg, Vivian; Bruun, Jack-Ansgar; Moe, Bjørn Thorvald Greve; Bartnes, Kristian; Busund, Lill-Tove; Chalmers, Anthony; Bremnes, Roy M.; Martinez, Inigo Zubiavrre. Consequential effects of ablative ionizing radiation on tumor stromal fibroblasts from lung tumors. Cell Symposia: Hallmarks of Cancer 2012-10-29 - 2012-10-31 2012.

Al-Shibli, Khalid; Al-Saad, Samer; Dønnem, Tom; Persson, Magnus L.; Bremnes, Roy M.; Busund, Lill-Tove. The Prognostic Value of Intraepithelial and Stromal Innate Immune System Cells in Non-Small Cell Lung Carcinoma. European Journal of Cancer 2012; Volum 48. ISSN 0959-8049.s S263 - S263.

Sørbye, Sveinung Wergeland; Kilvær, Thomas Karsten; Valkov, Andrey Yurjevich; Dønnem, Tom; Smeland, Eivind; Al-Shibli, Khalid Ibrahim; Bremnes, Roy M.; Busund, Lill-Tove. High expression of CD20+ lymphocytes in soft tissue sarcomas is a positive prognostic indicator. Oncoimmunology 2012; Volum 1 (1). ISSN 2162-4011.s 75 - 77.s doi: 10.4161/onci.1.1.17825.

Hellevik, Turid; Pettersen, Inger; Winberg, Jan-Olof; Berg, Vivian; Paulssen, Ruth H; Bartnes, Kristian; Busund, Lill-Tove; Bremnes, Roy M.; Martinez, Inigo Zubiavrre. The Impact of Ionizing Radiation on the Motility and Matrix Remodelling Properties of Carcinoma-associated Fibroblasts. European Journal of Cancer 2011; Volum 47. ISSN 0959-8049.s S142 - S143.

Valkov, Andrey Yurjevich; Sorbye, SW; Kilvaer, TK; Dønnem, Tom; Smeland, Eivind; Bremnes, Roy M.; Busund, Lill-Tove. The prognostic impact of Akt isoforms, PI3K and PTEN in soft tissue sarcomas. International Journal of Molecular Medicine 2011; Volum 28. ISSN 1107-3756.s S41 - S41.

Jantus, E; Sanmartin, E; Blasco, A; Sirera, R; Guijarro, R; Dønnem, Tom; Al-Saad, Samer; Busund, Lill-Tove Rasmussen; Bremnes, Roy M.; Camps, C. PDGF LIGANDS AND RECEPTORS: EXPRESSION IN TUMOR CELLS AND STROMA IN NSCLC. Journal of Thoracic Oncology 2010; Volum 5 (5). ISSN 1556-0864.s S58 - S59.

Lønvik, Kenneth; Eklo, Katrine; Berg, thomas; Dønnem, Tom; Bremnes, Roy M.; Busund, Lill-Tove Rasmussen. Prognostic impact of miR-126 and miR-155 expression in non-small cell lung cancer. APMIS - Journal of Pathologiy, Microbiology and Immunology 2010; Volum 118 (3). ISSN 0903-4641.s 248 - 249.

Al-Saad, Samer; Al-Shibli, Khalid Ibrahim; Dønnem, Tom; Andersen, Sigve; Bremnes, Roy M.; Busund, Lill-Tove Rasmussen. Simultaneous Expression of EGFR, HER2, HER3 and HER4 in Non-Small Cell Lung Cancer NSCLC: Correlation With Clinical Outcome and a Comparison Between Immunohistochemical Protein Expression and Silver In Situ Hybridization (SISH) For Detection of HER2 Gene Amplification. APMIS - Journal of Pathologiy, Microbiology and Immunology 2010; Volum 118 (3). ISSN 0903-4641.s 245 - 246.

Valkov, Andrey Yurjevich; Sørbye, Sveinung Wergeland; Kilvaer, TK; Dønnem, Tom; Smeland, E; Busund, Lill-Tove Rasmussen. Prognostic impact of TGF-beta 1 expression in non-GIST soft tissue sarcomas. APMIS - Journal of Pathologiy, Microbiology and Immunology 2010; Volum 118 (3). ISSN 0903-4641.s 247 - 247.

Sørbye, Sveinung Wergeland; Valkov, Andrey Yurjevich; Kilvær, T; Dønnem, Tom; Smeland, E; Al-Shibli, Khalid Ibrahim; Bremnes, Roy M.; Busund, Lill-Tove Rasmussen. Prognostic impact of lymphocyte infiltration in tumor and capsule in soft tissue sarcomas. APMIS - Journal of Pathologiy, Microbiology and Immunology 2010; Volum 118 (3). ISSN 0903-4641.s 246 - 247.

Al-Saad, Samer; Dønnem, Tom; Al-Shibli, Khalid; Persson, Magnus L.; Bremnes, Roy M.; Busund, Lill-Tove. Diverse prognostic roles of akt isoforms, PTEN and PI3K in tumor epithelial cells and stromal compartment in non-small cell lung cancer. Virchows Archiv 2009; Volum 455. ISSN 0945-6317.s 83 - 83.

Sanmartín, Elena; Lewintre, Eloisa Jantus; Sirera, Rafael; Dønnem, Tom; Busund, Lill-Tove; Lønvik, Kenneth; Bremnes, Roy M.; Camps, Carlos. Angiogenic marker expression in tumor cells versus stromal cells in non-small cell lung cancer. Journal of Thoracic Oncology 2009; Volum 4 (9). ISSN 1556-0864.s S638 - S638.

Al-Saad, Samer; Al-Shibli, Khalid; Dønnem, Tom; Persson, Magnus L.; Bremnes, Roy M.; Busund, Lill-Tove. A prognostic implication of epithelial mesenchymal transition markers in non-small cell lung cancer. Virchows Archiv 2009; Volum 455. ISSN 0945-6317.s 393 - 394.

Al-Saad, Samer; Dønnem, Tom; Al-Shibli, Khalid Ibrahim; Persson, Magnus L.; Bremnes, Roy M.; Busund, Lill-Tove Rasmussen. Diverse prognostic roles of Akt isoforms, PTEN and PI3K in tumor epithelial cells and stromal compartment in non-small cell lung cancer. APMIS - Journal of Pathologiy, Microbiology and Immunology 2009; Volum 117 (3). ISSN 0903-4641.s 233 - 234.

Andersen, Sigve; Eilertsen, Marte; Dønnem, Tom; Al-Saad, Samer; Al-Shibli, Khalid Ibrahim; Busund, Lill-Tove Rasmussen; Bremnes, Roy M.. Diverging prognostic impacts of hypoxic markers in histologic non-small cell lung cancer (NSCLC) subtypes. Journal of Thoracic Oncology 2009; Volum 4 (9). ISSN 1556-0864.s S386 - S387.

Dønnem, Tom; Al-Saad, Samer; Al-Shibli, Khalid Ibrahim Mahdi; Delghandi, Marit Pedersen; Persson, Magnus L.; Nilsen, Marit Nina; Busund, Lill-Tove Rasmussen; Bremnes, Roy M.. Prognostic impact of angiogenic markers in tumor and stromal cells in non-small cell lung cancer (NSCLC). Journal of Clinical Oncology 2007; Volum 25 (18S). ISSN 0732-183X.s doi: 2007ASCOAnnualMeetingProceedings.

Dønnem, Tom; Al-Shibli, Khalid Ibrahim Mahdi; Al-Saad, Samer; Delghandi, Marit Pedersen; Busund, Lill-Tove Rasmussen; Bremnes, Roy M.. Expression of vascular endothelial growth factors (VEGFs) A, C, D and receptors (VEGFRs) 1, 2 and 3, in both tumor cells and tumor stroma of non-small cell lung cancer (NSCLC): correlation with lymph node metastasis. Journal of Thoracic Oncology 2007; Volum 2. ISSN 1556-0864.s S327 - S327.s doi: OralPresentation12thWorldConferenceonLungCancer.

Al-Shibli, Khalid Ibrahim Mahdi; Dønnem, Tom; Al-Saad, Samer; Persson, Magnus L.; Bremnes, Roy M.; Busund, Lill-Tove Rasmussen. Prognostic impact of intraepithelial and stromal lymphocytic infiltrate in non-small celle lung cancer. Virchows Archiv 2007; Volum 451 (2). ISSN 0945-6317.

Busund, Lill-Tove Rasmussen; Seljelid, R. The making of monsters. Fusion of cancer cells and macrophages in vitro and in vivo. Cell fusion, epigenetics and cancer. The making of monsters. 09.09.05-09.09.05 2005-09-09 - 2005-09-09 2005.

Busund, Lill-Tove Rasmussen; Seljelid, Rolf. The making of monsters. Foredrag 2005 2005-09-15 - 2005-09-17 2005.

Sørbye, Sveinung W; Isaksen, vidar; Valkov, A; Smeland, E; Norum, J; Busund, Lill-Tove Rasmussen. Molecular prognostic markers in soft tissue sarcoma. Foredrag 2005-11-28 - 2005-11-28 2005.

Busund, Lill-Tove Rasmussen. FOU Rapport om Teknologisk samhandling innen laboratoriemedisin UNN/med fak, Uitø. 2005.