1. Unit startpage
  2. Employees
  3. Ingebrigt Sylte
Sylte.png
Sylte.png
Molekylær farmakologi og toksikologi ingebrigt.sylte@uit.no 77644705 TROM MH L9.121

Sylte, Ingebrigt

Professor, research group leader,

  • Rahman, Fatema; Nguyen, Tra-Mi; Adekoya, Olayiwola; Campestre, Cristina; Tortorella, Paolo; Sylte, Ingebrigt; Winberg, Jan-Olof. Inhibition of bacterial and human zincmetalloproteases by bisphosphonate- and catechol-containing compounds. Journal of Enzyme Inhibition and Medicinal Chemistry 2021; Volum 36 (1). ISSN 1475-6366.s 819 - 830.s doi: 10.1080/14756366.2021.1901088.
  • Ezawa, Takuya; Saito, Ryosuke; Suzuki, Shusuke; Sugiyama, Satoshi; Sylte, Ingebrigt; Kurita, Noriyuki. Protonation states of central amino acids in a zinc metalloprotease complexed with inhibitor: Molecular mechanics optimizations and ab initio molecular orbital calculations. Biophysical Chemistry 2020. ISSN 0301-4622.s doi: 10.1016/j.bpc.2020.106368.
  • Dawadi, Rangita; Malla, Nabin; Hegge, Beate; Wushur, Imin; Berg, Eli; Svineng, Gunbjørg; Sylte, Ingebrigt; Winberg, Jan-Olof. Molecular Interactions Stabilizing the Promatrix Metalloprotease-9·Serglycin Heteromer. International Journal of Molecular Sciences 2020; Volum 21 (12). ISSN 1422-0067.s 4205 - .s doi: 10.3390/ijms21124205.
  • Evenseth, Linn; Ocello, Riccardo; Gabrielsen, Mari; Masetti, Matteo; Recanatini, Maurizio; Sylte, Ingebrigt; Cavalli, Andrea. Exploring Conformational Dynamics of the Extracellular Venus flytrap Domain of the GABA B Receptor: A Path-Metadynamics Study. Journal of Chemical Information and Modeling 2020; Volum 60 (4). ISSN 1549-9596.s 2294 - 2303.s doi: 10.1021/acs.jcim.0c00163.
  • Evenseth, Linn; Gabrielsen, Mari; Sylte, Ingebrigt. The GABAB Receptor—Structure, Ligand Binding and Drug Development. Molecules 2020; Volum 25 (13). ISSN 1420-3049.s 1 - 19.s doi: 10.3390/molecules25133093.
  • Mortensen, Åse-Karen; Mæhre, Silje; Kristiansen, kurt; Heimstad, Eldbjørg Sofie; Gabrielsen, Geir W.; Jenssen, Bjørn Munro; Sylte, Ingebrigt. Homology modeling to screen for potential binding of contaminants to thyroid hormone receptor and transthyretin in glaucous gull (Larus hyperboreus) and herring gull (Larus argentatus). Computational Toxicology 2020; Volum 13:100120. ISSN 2468-1113.s 1 - 8.s doi: 10.1016/j.comtox.2020.100120.
  • Ezawa, Takuya; Sugiyama, Satoshi; Ara, Ayami; Sylte, Ingebrigt; Kurita, Noriyuki. Design of galardine analogs as putative psudolysin inhibitors based on ab initio fragment molecular orbital calculations. Journal of Biomolecular Structure and Dynamics 2019. ISSN 0739-1102.s doi: 10.1080/07391102.2019.1656672.
  • Arnesen, Liv Henriette; Haj Yasein, Nadia; Tungen, Jørn Eivind; Södling, Helen; Matthews, Jason; Paulsen, Steinar M; Nebb, Hilde Irene; Sylte, Ingebrigt; Hansen, Trond Vidar; Sæther, Thomas. Molecular modelling, synthesis, and biological evaluations of a 3,5-disubstituted isoxazole fatty acid analogue as a PPARα-selective agonist. (fulltekst) Bioorganic & Medicinal Chemistry 2019; Volum 27 (18). ISSN 0968-0896.s 4059 - 4068.s doi: 10.1016/j.bmc.2019.07.032.
  • Evenseth, Linn; Warszycki, Dawid; Bojarski, Andrzej J; Gabrielsen, Mari; Sylte, Ingebrigt. In Silico Methods for the Discovery of Orthosteric GABAB Receptor Compounds. Molecules 2019; Volum 24 (5). ISSN 1420-3049.s 1 - 20.s doi: 10.3390/molecules24050935.
  • Evenseth, Linn M; Kristiansen, Kurt; Song, You; Tollefsen, Knut Erik; Sylte, Ingebrigt. In silico site-directed mutagenesis of the Daphnia magna ecdysone receptor identifies critical amino acids for species-specific and inter-species differences in agonist binding. Computational Toxicology 2019; Volum 12. ISSN 2468-1113.s doi: 10.1016/j.comtox.2019.100091.
  • Fjelldal, Marthe Fredheim; Freyd, Thibaud; Evenseth, Linn; Sylte, Ingebrigt; Ring, Avi; Paulsen, Ragnhild Elisabeth. Exploring the overlapping binding sites of ifenprodil and EVT‐101 in GluN2B‐containing NMDA receptors using novel chicken embryo forebrain cultures and molecular modeling. Pharmacology Research & Perspectives 2019; Volum 7 (3). ISSN 2052-1707.s 1 - 15.s doi: 10.1002/prp2.480.
  • Doering, Jon A.; Lee, Sehan; Kristiansen, kurt; Evenseth, Linn; Sylte, Ingebrigt; Barron, Mace G.; Lalone, Carlie. In silico site-directed mutagenesis informs species-specific predictions of chemical susceptibility derived from the Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) tool. Toxicological Sciences 2018; Volum 166 (1). ISSN 1096-6080.s 131 - 145.s doi: 10.1093/toxsci/kfy186.
  • Al-Kazaale, Nora; Tran, Phuong Dan Dinh; Haidari, Farhad; Solum, Eirik Johansson; Liekens, Sandra; Vervaeke, Peter; Sylte, Ingebrigt; Cheng, Jing-Jy; Vik, Anders; Hansen, Trond Vidar. Synthesis, molecular modeling and biological evaluation of potent analogs of 2-methoxyestradiol. Steroids 2018; Volum 136. ISSN 0039-128X.s 47 - 55.s doi: 10.1016/j.steroids.2018.05.002.
  • Hill, Katie L.; Mortensen, Åse-Karen; Teclechiel, Daniel; Willmore, William G.; Sylte, Ingebrigt; Jenssen, Bjørn Munro; Letcher, Robert James. In Vitro and in Silico Competitive Binding of Brominated Polyphenyl Ether Contaminants with Human and Gull Thyroid Hormone Transport Proteins. Environmental Science and Technology 2018; Volum 52 (3). ISSN 0013-936X.s 1533 - 1541.s doi: 10.1021/acs.est.7b04617.
  • Sylte, Ingebrigt; Dawadi, Rangita; Malla, Nabin; von Hofsten, Susannah; Nguyen, Tra-Mi; Solli, Ann Iren; Berg, Eli; Adekoya, Olayiwola; Svineng, Gunbjørg; Winberg, Jan-Olof. The selectivity of galardin and an azasugar-based hydroxamate compound for human Matrix metalloproteases and bacterial metalloproteases. PLOS ONE 2018; Volum 13 (8). ISSN 1932-6203.s doi: 10.1371/journal.pone.0200237.
  • Åstrand, Ove Alexander Høgmoen; Viktorsson, Elvar Örn; Kristensen, Aleksander Lim; Ekeberg, Dag; Røberg-Larsen, Hanne; Wilson, Steven Ray Haakon; Gabrielsen, Mari; Sylte, Ingebrigt; Rustan, Arild; Thoresen, G. Hege; Rongved, Pål; Kase, Eili Tranheim. Synthesis, in vitro and in vivo biological evaluation of new oxysterols as modulators of the liver X receptors. Journal of Steroid Biochemistry and Molecular Biology 2017; Volum 165. ISSN 0960-0760.s 323 - 330.s doi: 10.1016/j.jsbmb.2016.07.010.
  • Viktorsson, Elvar Örn; Gabrielsen, Mari; Kumarachandran, Nugalya; Sylte, Ingebrigt; Rongved, Pål; Åstrand, Ove Alexander Høgmoen; Kase, Eili Tranheim. Regulation of liver X receptor target genes by 22-functionalized oxysterols. Synthesis, in silico and in vitro evaluations. Steroids 2017; Volum 118. ISSN 0039-128X.s 119 - 127.s doi: 10.1016/j.steroids.2016.12.003.
  • Chilmonczyk, Zdzislaw; Bojarski, Andrzej J.; Pilc, Andrzej; Sylte, Ingebrigt. Serotonin transporter and receptor ligands with antidepressant activity as neuroprotective and proapoptotic agents. Pharmacological Reports 2017; Volum 69 (3). ISSN 1734-1140.s 469 - 478.s doi: 10.1016/j.pharep.2017.01.011.
  • Warszycki, Dawid; Rueda, Manuel; Mordalski, Stefan; Kristiansen, kurt; Satala, Grzegorz; Rataj, Krzysztof; Chilmonczyk, Zdzislaw; Sylte, Ingebrigt; Abagyan, Ruben; Bojarski, Andrzej J. From Homology Models to a Set of Predictive Binding Pockets-a 5-HT<sub>1A</sub> Receptor Case Study. Journal of Chemical Information and Computer Sciences 2017; Volum 57 (2). ISSN 0095-2338.s 311 - 321.s doi: 10.1021/acs.jcim.6b00263.
  • Freyd, Thibaud; Warszycki, Dawid; Mordalski, Stefan; Bojarski, Andrzej J; Sylte, Ingebrigt; Gabrielsen, Mari. Ligand-guided homology modelling of the GABA<sub>B2</sub> subunit of the GABA<sub>B</sub> receptor. PLOS ONE 2017; Volum 12 (3). ISSN 1932-6203.s doi: 10.1371/journal.pone.0173889.
  • Ara, Ayami; Kadoya, Ryushi; Ishimura, Hiromi; Shimamura, Kanako; Sylte, Ingebrigt; Kurita, Noriyuki. Specific interactions between zinc metalloproteinase and its inhibitors: Ab initio fragment molecular orbital calculations. Journal of Molecular Graphics and Modelling 2017; Volum 75. ISSN 1093-3263.s 277 - 286.s doi: 10.1016/j.jmgm.2017.05.013.
  • Routti, Heli Anna Irmeli; Lille-Langøy, Roger; Berg, Mari Katrine; Fink, Trine; Harju, Mikael; Kristiansen, Kurt; Rostkowski, Pawel Marian; Rusten, Marte; Sylte, Ingebrigt; Øygarden, Lene Eidsvik; Goksøyr, Anders. Environmental chemicals modulate polar bear (Ursus maritimus) Peroxisome Proliferator-Activated Receptor Gamma (PPARG) and adipogenesis in vitro. Environmental Science and Technology 2016; Volum 50 (19). ISSN 0013-936X.s 10708 - 10720.s doi: 10.1021/acs.est.6b03020.
  • Sjøli, Stian; Nuti, Elisa; Camodeca, Caterina; Bilto, Irina; Rossello, Armando; Winberg, Jan-Olof; Sylte, Ingebrigt; Adekoya, Olayiwola. Synthesis, experimental evaluation and molecular modelling of hydroxamate derivatives as zinc metalloproteinase inhibitors. European Journal of Medicinal Chemistry 2016; Volum 108. ISSN 0223-5234.s 141 - 153.s doi: 10.1016/j.ejmech.2015.11.019.
  • Wushur, Imin; Sylte, Ingebrigt; Winberg, Jan-Olof. The catalytic reaction mechanism of drosophilid alcohol dehydrogenases. Perspectives in Science 2015; Volum 4. ISSN 2213-0209.s 46 - 56.s doi: 10.1016/j.pisc.2014.12.008.
  • Kaupang, Åsmund; Paulsen, Steinar Martin; Steindal, Calin Constantin; Ravna, Aina Westrheim; Sylte, Ingebrigt; Halvorsen, Trine Grønhaug; Thoresen, G. Hege; Hansen, Trond Vidar. Synthesis, biological evaluation and molecular modeling studies of the PPARβ/δ antagonist CC618. European Journal of Medicinal Chemistry 2015; Volum 94. ISSN 0223-5234.s 229 - 236.s doi: 10.1016/j.ejmech.2015.03.006.
  • Solum, Eirik Johansson; Cheng, Jing-Jy; Sylte, Ingebrigt; Vik, Anders; Hansen, Trond Vidar. Synthesis, biological evaluation and molecular modeling of new analogs of the anti-cancer agent 2-methoxyestradiol: potent inhibitors of angiogenesis. RSC Advances 2015; Volum 5 (41). ISSN 2046-2069.s 32497 - 32504.s doi: 10.1039/c5ra03570h.
  • Chilmonczyk, Zdzislaw; Bojarski, Andrzej Jacek; Pilc, Andrzej; Sylte, Ingebrigt. Functional selectivity and antidepressant activity of serotonin 1A receptor ligands. International Journal of Molecular Sciences 2015; Volum 16 (8). ISSN 1422-0067.s 18474 - 18506.s doi: 10.3390/ijms160818474.
  • Odunuga, Odutayo O.; Adekoya, Olayiwola; Sylte, Ingebrigt. High-level expression of pseudolysin, the extracellular elastase of Pseudomonas aeruginosa, in Escherichia coli and its purification. Protein Expression and Purification 2015; Volum 113. ISSN 1046-5928.s 79 - 84.s doi: 10.1016/j.pep.2015.05.005.
  • Kufareva, Irina; Katritch, Vsevolod; Freyd, Thibaud; Gabrielsen, Mari; Kristiansen, kurt; Sylte, Ingebrigt; Stevens, Raymond C.; Abagyan, Ruben. Advances in GPCR modeling evaluated by the GPCR Dock 2013 assessment: Meeting new challenges. Structure 2014; Volum 22 (8). ISSN 0969-2126.s 1120 - 1139.s doi: 10.1016/j.str.2014.06.012.
  • Jantan, Ibrahim; Bukhari, Syed Nasir Abbas; Adekoya, Olayiwola; Sylte, Ingebrigt. Studies of synthetic chalcone derivatives as potential inhibitors of secretory phospholipase A<sub>2</sub>, cyclooxygenases, lipoxygenase and pro-inflammatory cytokines. Drug Design, Development and Therapy 2014; Volum 8. ISSN 1177-8881.s 1405 - 1418.s doi: 10.2147/DDDT.S67370.
  • Adekoya, Olayiwola; Sjøli, Stian; Wushur, Imin; Bilto, Irina; Marques, Sergio M; Santos, M Amelia; Nuti, Elisa; Cercignani, Giovanni; Rossello, Armando; Winberg, Jan-Olof; Sylte, Ingebrigt. Inhibition of pseudolysin and thermolysin by hydroxamate-based MMP inhibitors. European Journal of Medicinal Chemistry 2014; Volum 89. ISSN 0223-5234.s 340 - 348.s doi: 10.1016/j.ejmech.2014.10.009.
  • Chilmonczyk, Zdzislaw; Bojarski, Andrzej J.; Sylte, Ingebrigt. Ligand-directed traffickingof receptor stimulus. Pharmacological Reports 2014; Volum 66 (6). ISSN 1734-1140.s 1011 - 1021.s doi: 10.1016/j.pharep.2014.06.006.
  • Wushur, Imin; Winberg, Jan-Olof; Sylte, Ingebrigt. Comparative molecular dynamic simulations of wild type and Thr114Val mutated Scaptodrosophila lebanonensis alcohol dehydrogenase. Journal of Biomolecular Structure and Dynamics 2014; Volum 32 (3). ISSN 0739-1102.s 465 - 476.s doi: 10.1080/07391102.2013.776502.
  • Gabrielsen, Mari; Kurczab, Rafal; Siwek, Agata; Wolak, Malgorzata; Ravna, Aina Westrheim; Kristiansen, kurt; Kufareva, Irina; Abagyan, Ruben; Nowak, Gabriel; Chilmonczyk, Zdzislaw; Sylte, Ingebrigt; Bojarski, Andrzej J.. Identification of novel serotonin transporter compounds by virtual Screening. Journal of Chemical Information and Modeling 2014; Volum 54 (3). ISSN 1549-9596.s 933 - 943.s doi: 10.1021/ci400742s.
  • Sjøli, Stian; Solli, Ann Iren; Akselsen, Øyvind Wilhelm; Jiang, Yang; Berg, Eli; Hansen, Trond Vidar; Sylte, Ingebrigt; Winberg, Jan-Olof. PAC-1 and isatin derivatives are weak matrix metalloproteinase inhibitors. Biochimica et Biophysica Acta 2014; Volum 10 (1840). ISSN 0006-3002.s 3162 - 3169.s doi: 10.1016/j.bbagen.2014.07.011.
  • Åstrand, Ove Alexander Høgmoen; Gikling, Ingveig; Sylte, Ingebrigt; Rustan, Arild; Thoresen, G. Hege; Rongved, Pål; Kase, Eili Tranheim. Development of new LXR modulators that regulate LXR target genes and reduce lipogenesis in human cell models. European Journal of Medicinal Chemistry 2014; Volum 74. ISSN 0223-5234.s 258 - 263.s doi: 10.1016/j.ejmech.2014.01.003.
  • Lindin, inger; Wuxiuer, Yimingjiang; Ravna, Aina Westrheim; Moens, Ugo; Sylte, Ingebrigt. Comparative molecular dynamics simulations of mitogen-activated protein kinase-activated protein kinase 5. International Journal of Molecular Sciences 2014; Volum 15 (3). ISSN 1422-0067.s 4878 - 4902.s doi: 10.3390/ijms15034878.
  • Åstrand, Ove Alexander Høgmoen; Sandberg, Marcel; Sylte, Ingebrigt; Gorbitz, Carl Henrik; Thoresen, G. Hege; Kase, Eili Tranheim; Rongved, Pål. Synthesis and initial biological evaluation of new mimics of the LXR-modulator 22(S)-hydroxycholesterol. Bioorganic & Medicinal Chemistry 2014; Volum 22 (1). ISSN 0968-0896.s 643 - 650.s doi: 10.1016/j.bmc.2013.10.024.
  • Sylte, Ingebrigt; Adekoya, Olayiwola. Thermolsyin. Springer 2013 ISBN 978-1-4614-1532-9.s 2213 - 2221.s doi: 10.1007/978-1-4614-1533-6.
  • Warszycki, Dawid; Mordalski, Stefan; Kristiansen, kurt; Kafel, Rafal; Sylte, Ingebrigt; Chilmonczyk, Zdzislaw; Bojarski, Andrzej J.. A Linear Combination of Pharmacophore Hypotheses as a New Tool in Search of New Active Compounds - An Application for 5-HT1A Receptor Ligands. PLOS ONE 2013; Volum 8 (12). ISSN 1932-6203.s doi: 10.1371/journal.pone.0084510.
  • Larsen, Anett Kristin; Kristiansen, kurt; Sylte, Ingebrigt; Seternes, Ole Morten; Bang, Berit. Differences in PAR-2 activating potential by king crab (Paralithodes camtschaticus), salmon (Salmo salar), and bovine (Bos taurus) trypsin. BMC Research Notes 2013; Volum 6. ISSN 1756-0500.s 281 - .s doi: 10.1186/1756-0500-6-281.
  • Wuxiuer, Yimingjiang; Winberg, Jan-Olof; Sylte, Ingebrigt. Comparative molecular dynamics simulations of wild type and Thr114Val mutated Scaptodrosophila lebanonensis alcohol dehydrogenase. Journal of Biomolecular Structure and Dynamics 2013; Volum 32 (3). ISSN 0739-1102.s 465 - 476.s doi: 10.1080/07391102.2013.776502.
  • Lindin, inger; Wuxiuer, Yimingjiang; Kufareva, Irina; Abagyan, Ruben; Moens, Ugo; Sylte, Ingebrigt; Ravna, Aina Westrheim. Homology modeling and ligand docking of Mitogen-activated protein kinase-activated protein kinase 5 (MK5). Theoretical Biology Medical Modelling 2013; Volum 10. ISSN 1742-4682.s doi: 10.1186/1742-4682-10-56.
  • Gabrielsen, Mari; Wolosewicz, Karol; Zawadzka, Anna; Kossakowski, Jerzy; Nowak, Gabriel; Wolak, Malgorzata; Stachowicz, Katarzyna; Siwek, Agata; Ravna, Aina Westrheim; Kufareva, Irina; Kozerski, Lech; Bednarek, Elzbieta; Sitkowski, Jerzy; Bocian, Wojciech; Abagyan, Ruben; Bojarski, Andrezej J; Sylte, Ingebrigt; Chilmonczyk, Zdzislaw. Synthesis, Antidepressant Evaluation and Docking Studies of Long-Chain Alkylnitroquipazines as Serotonin Transporter Inhibitors. Chemical Biology and Drug Design (CB&DD) 2013; Volum 81 (6). ISSN 1747-0277.s 695 - 706.s doi: 10.1111/cbdd.12116.
  • Baglo, Yan; Gabrielsen, Mari; Sylte, Ingebrigt; Gederaas, Odrun Arna. Homology Modeling of Human <gamma>-Butyric Acid Transporters and the Binding of Pro-drugs 5-Aminolevulinic Acid and Methyl Aminolevulinic Acid used in Photodynamic Therapy. PLOS ONE 2013; Volum 8 (6). ISSN 1932-6203.s doi: 10.1371/journal.pone.0065200.
  • Khan, Mahmud Tareq Hassan; Dedachi, Kenichi; Matsui, Toshiro; Kurita, Noriyuki; Borgatti, Monica; Gambari, Roberto; Sylte, Ingebrigt. Dipeptide Inhibitors of Thermolysin and Angiotensin I-Converting Enzyme. Current Topics in Medicinal Chemistry 2012; Volum 12 (16). ISSN 1568-0266.s 1748 - 1762.s doi: 10.2174/1568026611209061748.
  • Gabrielsen, Mari; Ravna, aina westrheim; Kristiansen, kurt; Sylte, Ingebrigt. Substrate binding and translocation of the serotonin transporter studied by docking and molecular dynamics simulations. Journal of Molecular Modeling 2012; Volum 18 (3). ISSN 1610-2940.s 1073 - 1085.s doi: 10.1007/s00894-011-1133-1.
  • Gabrielsen, Mari; Kurczab, Rafal; Ravna, aina westrheim; Kufareva, Irina; Abagyan, Ruben; Chilmonczyk, Zdzislaw; Bojarski, Andrezej J; Sylte, Ingebrigt. Molecular mechanism of serotonin transporter inhibition elucidated by a new flexible docking protocol. European Journal of Medicinal Chemistry 2012; Volum 47. ISSN 0223-5234.s 24 - 37.s doi: 10.1016/j.ejmech.2011.09.056.
  • Sylte, Ingebrigt; Ravna, aina westrheim. Homology Modeling of Transporter Proteins (Carriers and Ion Channels). Humana Press 2012 (857). ISSN 1064-3745.s 281 - 299.s doi: 10.1007/978-1-61779-588-6_12.
  • Khan, Mahmud Tareq Hassan; Wuxiuer, Yimingjiang; Sylte, Ingebrigt. Binding Modes and Pharmacophore Modelling of Thermolysin Inhibitors. Mini-Reviews in Medicinal Chemistry 2012; Volum 12 (6). ISSN 1389-5575.s 515 - 533.
  • Fadnes, Bodil Irene; Hadler-Olsen, Elin Synnøve; Sylte, Ingebrigt; Uhlin-Hansen, Lars; Winberg, Jan-Olof. Matrix metalloproteinase complexes and their biological significance. Walter de Gruyter 2012 ISBN 978-3-11-025876-9.s 291 - 314.s doi: 10.1515/9783110258776.291.
  • Wuxiuer, Yimingjiang; Morgunova, Ekaterina; Cols, Neus; Popov, Alexander; Karshikoff, Andrey; Sylte, Ingebrigt; Gonzàlez-Duarte, Roser; Ladenstein, Rudolf; Winberg, Jan-Olof. An intact eight-membered water chain in drosophilid alcohol dehydrogenases is essential for optimal enzyme activity. The FEBS Journal 2012; Volum 279 (16). ISSN 1742-464X.s 2940 - 2956.s doi: 10.1111/j.1742-4658.2012.08675.x.
  • Jaronczyk, Malgorzata; Wolosewicz, Karol; Gabrielsen, Mari; Nowak, Gabriel; Kufareva, Irina; Mazurek, Aleksander P; Ravna, aina westrheim; Abagyan, Ruben; Bojarski, Andrezej J; Sylte, Ingebrigt; Chilmonczyk, Zdzislaw. Synthesis, in vitro binding studies and docking of long-chain arylpiperazine nitroquipazine analogues, as potential serotonin transporter inhibitors. European Journal of Medicinal Chemistry 2012; Volum 49. ISSN 0223-5234.s 200 - 210.s doi: 10.1016/j.ejmech.2012.01.012.
  • Hirakawa, Tatsuya; Fujita, Seiya; Ohyama, Tatsuya; Dedachi, Kenichi; Khan, Mahmud Tareq Hassan; Sylte, Ingebrigt; Kurita, Noriyuki. Specific interactions and binding energies between thermolysin and potent inhibitors: Molecular simulations based on ab initio molecular orbital method. Journal of Molecular Graphics and Modelling 2012; Volum 33. ISSN 1093-3263.s 1 - 11.s doi: 10.1016/j.jmgm.2011.10.006.
  • Witowska-Jarosz, Janina; Jaronczyk, Malgorzata; Mazurek, Aleksander P; Sylte, Ingebrigt; Bojarski, Andrezej J; Chilmonczyk, Zdzislaw; Jarosz, Maciej. Mass-spectrometric studies of new 6-nitroquipazines-serotonin transporter inhibitors. Analytical and Bioanalytical Chemistry 2012; Volum 402 (1). ISSN 1618-2642.s 537 - 541.s doi: 10.1007/s00216-011-5410-8.
  • Hessvik, Nina Pettersen; Bakke, Siril Skaret; Smith, Robert; Ravna, aina westrheim; Sylte, Ingebrigt; Rustan, Arild; Thoresen, G. Hege; Kase, Eili Tranheim. The liver X receptor modulator 22(S)-hydroxycholesterol exerts cell-type specific effects on lipid and glucose metabolism. Journal of Steroid Biochemistry and Molecular Biology 2012; Volum 128. ISSN 0960-0760.s 154 - 164.s doi: 10.1016/j.jsbmb.2011.10.006.
  • Sylte, Ingebrigt; Ravna, aina westrheim; Dahl, Svein G.. Templates and models of monoamine transporter proteins. Current Medicinal Chemistry 2011; Volum 18 (30). ISSN 0929-8673.s 4651 - 4658.
  • Dedachi, Kenichi; Hirakawa, Tatsuya; Fujita, Seiya; Khan, Mahmud Tareq Hassan; Sylte, Ingebrigt; Kurita, Noriyuki. Specific Interactions and Binding Free Energies Between Thermolysin and Dipeptides: Molecular Simulations Combined with Ab Initio Molecular Orbital and Classical Vibrational Analysis. Journal of Computational Chemistry 2011; Volum 32 (14). ISSN 0192-8651.s 3047 - 3057.s doi: 10.1002/jcc.21887.
  • Mordalski, Stefan; Kosciolek, Tomasz; Kristiansen, kurt; Sylte, Ingebrigt; Bojarski, Andrezej J. Protein binding site analysis by means of structural interaction fingerprint patterns. Bioorganic & Medicinal Chemistry Letters 2011; Volum 21 (22). ISSN 0960-894X.s 6816 - 6819.s doi: 10.1016/j.bmcl.2011.09.027.
  • Ciocoiu, Calin C.; Ravna, aina westrheim; Sylte, Ingebrigt; Rustan, Arild; Hansen, Trond Vidar. Synthesis, molecular modeling studies and biological evaluation of fluorine substituted analogs of GW 501516. Bioorganic & Medicinal Chemistry 2011; Volum 19. ISSN 0968-0896.s 6982 - 6988.s doi: 10.1016/j.bmc.2011.10.020.
  • Kostenko, Sergiy Viktorovich; Khan, Mahmud Tareq Hassan; Sylte, Ingebrigt; Moens, Ugo. The diterpenoid alkaloid noroxoaconitine is a Mapkap kinase 5 (MK5/PRAK) inhibitor. Cellular and Molecular Life Sciences (CMLS) 2011; Volum 68 (2). ISSN 1420-682X.s 289 - 301.s doi: 10.1007/s00018-010-0452-1.
  • Hadler-Olsen, Elin Synnøve; Fadnes, Bodil Irene; Sylte, Ingebrigt; Uhlin-Hansen, Lars; Winberg, Jan-Olof. Regulation of matrix metalloproteinase activity in health and disease. The FEBS Journal 2011; Volum 278 (1). ISSN 1742-464X.s 28 - 45.s doi: 10.1111/j.1742-4658.2010.07920.x.
  • Ciocoiu, Calin Constantin; Ravna, aina westrheim; Sylte, Ingebrigt; Hansen, Trond Vidar. Synthesis, Biological Evaluation and Molecular Modeling of GW 501516 Analogues. Archiv der Pharmazie 2010; Volum 343 (11-12). ISSN 0365-6233.s 612 - 624.s doi: 10.1002/ardp.201000189.
  • Kostenko, Sergiy Viktorovich; Khan, Mahmud Tareq Hassan; Moens, Ugo; Sylte, Ingebrigt. The diterpenoid alkaloid Noroxoaconitine is a MAPKAP Kinase 5 (MK5/PRAK) inhibitor. Cellular and Molecular Life Sciences (CMLS) 2010. ISSN 1420-682X.s doi: 10.1007/s00018-010-0452-1.
  • Khan, Mahmud Tareq Hassan; Khan, R.; Wuxiuer, Yimingjiang; Arfan, M.; Ahmed, M.; Sylte, Ingebrigt. Identification of novel quinazolin-4(3H)-ones as inhibitors of thermolysin, the prototype of the M4 family of proteinases. Bioorganic & Medicinal Chemistry 2010; Volum 18 (12). ISSN 0968-0896.s 4317 - 4327.s doi: 10.1016/j.bmc.2010.04.083.
  • Kurczab, Rafal; Nowak, Mateusz; Chilmonczyk, Zdzislaw; Sylte, Ingebrigt; Bojarski, Andrezej J. The development and validation of a novel virtual screening cascade protocol to identify potential serotonin 5-HT7R antagonists. Bioorganic & Medicinal Chemistry Letters 2010; Volum 20 (8). ISSN 0960-894X.s 2465 - 2468.s doi: 10.1016/j.bmcl.2010.03.012.
  • Odlo, Kristin; Fournier-Dit-Chabert, Jérémie; Ducki, Sylvie; Gani, Osman A.B.S.M.; Sylte, Ingebrigt; Hansen, Trond Vidar. 1,2,3-Triazole analogs of combretastatin A-4 as potential microtubule-binding agents. Bioorganic & Medicinal Chemistry 2010; Volum 18 (18). ISSN 0968-0896.s 6874 - 6885.s doi: 10.1016/j.bmc.2010.07.032.
  • Khan, Mahmud Tareq Hassan; Fuskevaag, OM; Sylte, Ingebrigt. Discovery of Potent Thermolysin Inhibitors Using Structure Based Virtual Screening and Binding Assays. Journal of Medicinal Chemistry 2009; Volum 52 (1). ISSN 0022-2623.s 48 - 61.s doi: 10.1021/jm8008019.
  • Ravna, aina westrheim; Sager, Georg; Dahl, Svein G.; Sylte, Ingebrigt. Membrane transporters: Structure, function and targets for drug design. Springer Publishing Company 2009 (4) ISBN 978-3-540-87911-4. ISSN 1862-2461.s 15 - 51.
  • Khan, Mahmud T. H.; Sylte, Ingebrigt. Structural Bioinformatics in the Discovery of Novel Drugs. Springer Science+Business Media B.V. 2009 ISBN 978-1-4020-6954-3.s 29 - 38.
  • Ravna, aina westrheim; Sylte, Ingebrigt; Sager, Georg. Binding site of ABC transporter homology models confirmed by ABCB1 crystal structure. Theoretical Biology Medical Modelling 2009; Volum 6 (20). ISSN 1742-4682.s doi: 10.1186/1742-4682-6-20.
  • Khan, Mahmud T. H.; Sylte, Ingebrigt. Multivariate Linear Regression Models Based on ADME Descriptors and Predictions of ADMET Profile for Structurally Diverse Thermolysin Inhibitors. Letters in Drug Design & Discovery 2009; Volum 6 (6). ISSN 1570-1808.s 428 - 436.
  • Khan, Mahmud T. H.; Sylte, Ingebrigt. Determinants for Psychrophilic and Thermophilic Features of Metallopeptidases of the M4 Family. In Silico Biology 2009; Volum 9. ISSN 1386-6338.s 105 - 124.s doi: 10.3233/ISB-2009-0392.
  • Ravna, aina westrheim; Sylte, Ingebrigt; Dahl, Svein G.. Structure and localisation of drug binding sites on neurotransmitter transporters. Journal of Molecular Modeling 2009; Volum 15 (10). ISSN 1610-2940.s 1155 - 1164.s doi: 10.1007/s00894-009-0478-1.
  • Herold, Franciszek; Izbicki, Lukasz; Chodkowski, Andrzej; Dawidowski, Maciej; Król, Marek; Kleps, Jerzy; Turlo, Jadwiga; Wolska, Irena; Nowak, Gabriel; Stachowicz, Katarzyna; Dybala, Malgorzata; Siwek, Agata; Nowak, Mateusz; Pieniazek, Elzbieta; Jaronczyk, Malgorzata; Sylte, Ingebrigt; Mazurek, Aleksander P. Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT1A activity: Part 2. European Journal of Medicinal Chemistry 2009; Volum 44. ISSN 0223-5234.s 4702 - 4715.s doi: 10.1016/j.ejmech.2009.07.007.
  • Dedachi, Kenichi; Khan, Mahmud T. H.; Sylte, Ingebrigt; Kurita, Noriyuki. A combined simulation with ab initio MO and classical vibrational analysis on the specific interactions between thermolysin and dipeptide ligands. Chemical Physics Letters 2009; Volum 479 (4-6). ISSN 0009-2614.s 290 - 295.s doi: 10.1016/j.cplett.2009.08.036.
  • Gani, Osman A.B.S.M.; Sylte, Ingebrigt. Molecular recognition of long chain fatty acids by peroxisome proliferator-activated receptor alpha. Medicinal Chemistry Research 2009; Volum 18 (1). ISSN 1054-2523.s 8 - 19.s doi: 10.1007/s00044-008-9102-7.
  • Adekoya, Olayiwola; Sylte, Ingebrigt. The Thermolysin Family (M4) of Enzymes: Therapeutic and Biotechnological Potential. Chemical Biology and Drug Design (CB&DD) 2009; Volum 73 (1). ISSN 1747-0277.s 7 - 16.s doi: 10.1111/j.1747-0285.2008.00757.x.
  • Gani, Osman A.B.S.M.; Sylte, Ingebrigt. Molecular recognition of docosahexaenoic acid by peroxisome proliferator-activated receptors and retinoid-X receptor alpha. Journal of Molecular Graphics and Modelling 2008; Volum 27. ISSN 1093-3263.s 217 - 224.s doi: 10.1016/j.jmgm.2008.04.008.
  • Odlo, K; Hentzen, J; dit Chabert, JF; Ducki, S; Gani, Osman A.B.S.M.; Sylte, Ingebrigt; Skrede, M; Flørenes, Vivi Ann; Florenes, VA; Hansen, TV. 1,5-disubstituted 1,2,3-triazoles as cis-restricted analogues of combretastatin A-4: Synthesis, molecular modeling and evaluation as cytotoxic agents and inhibitors of tubulin. Bioorganic & Medicinal Chemistry 2008; Volum 16. ISSN 0968-0896.s 4829 - 4838.s doi: 10.1016/j.bmc.2008.03.049.
  • Gani, Osman A.B.S.M.; Sylte, Ingebrigt. Ligand-induced stabilization and activation of peroxisome proliferator-activated receptor gamma. Chemical Biology and Drug Design (CB&DD) 2008; Volum 72. ISSN 1747-0277.s 50 - 57.s doi: 10.1111/j.1747-0285.2008.00677.x.
  • Gani, Osman A.B.S.M.; Adekoya, Olayiwola; Giurato, L; Spyrakis, F; Cozzini, P; Guccione, S; Winberg, Jan-Olof; Sylte, Ingebrigt. Theoretical calculations of the catalytic triad in short-chain alcohol dehydrogenases/reductases. Biophysical Journal 2008; Volum 94. ISSN 0006-3495.s doi: 10.1529/biophysj.107.111096.
  • Dahl, Svein G.; Sylte, Ingebrigt. Molecular Structure and Dynamics of Drug Targets. Prague Medical Report 2008; Volum 109 (2-3). ISSN 1214-6994.s 107 - 112.
  • Ravna, aina westrheim; Sylte, Ingebrigt; Sager, Georg. A molecular model of a putative substrate releasing conformation of multidrug resistance protein 5 (MRP5). European Journal of Medicinal Chemistry 2008; Volum 43 (11). ISSN 0223-5234.s 2557 - 2567.s doi: 10.1016/j.ejmech.2008.01.015.
  • Jaronczyk, Malgorzata; Chilmonczyk, Zdizlav; Mazurek, AP; Nowak, Gabriel; Ravna, aina westrheim; Kristiansen, kurt; Sylte, Ingebrigt. The molecular interactions of buspirone analogues with the serotonin transporter. Bioorganic & Medicinal Chemistry 2008; Volum 16 (20). ISSN 0968-0896.s 9283 - 9294.s doi: 10.1016/j.bmc.2008.09.005.
  • Kvernmo, Trond; Houben, John; Sylte, Ingebrigt. Receptor-binding and pharmacokinetic properties of dopaminergic agonists. Current Topics in Medicinal Chemistry 2008; Volum 8 (12). ISSN 1568-0266.s 1049 - 1067.
  • Ravna, aina westrheim; Sylte, Ingebrigt; Sager, Georg. Molecular model of the outward facing state of the human P-glycoprotein (ABCB1), and comparison to a model of the human MRP5 (ABCC5). Theoretical Biology Medical Modelling 2007; Volum 4. ISSN 1742-4682.s 33 - .
  • Khan, Mahmud Tareq Hassan; Wuxiuer, Yimingjiang; Sylte, Ingebrigt. Molecular recognition of thermolysin and homologous zinc-metalloproteinases. Minerva biotecnologica (Testo stampato) 2007; Volum 19. ISSN 1120-4826.s 139 - 150.
  • Khan, Mahmud Tareq Hassan; Sylte, Ingebrigt. Predictive QSAR modeling for the sucessful predictions of the ADMET properties of candidate drug molecules. Current Drug Discovery Technologies 2007; Volum 4. ISSN 1570-1638.s 141 - 149.
  • Ravna, Aina Westrheim; Jaronczyk, Malgorzata; Sylte, Ingebrigt. A homology model of SERT based on the LeuT(Aa) template. Bioorganic & Medicinal Chemistry Letters 2006; Volum 16. ISSN 0960-894X.s 5594 - 5597.
  • Dahl, Svein G.; Sylte, Ingebrigt. From genomics to drug targets. Journal of Psychopharmacology 2006; Volum 20 (4). ISSN 0269-8811.s 95 - 99.
  • Adekoya, Olayiwola; Helland, Ronny; Willassen, Nils P; Sylte, Ingebrigt. Comparative sequence and structure analysis reveal features of cold adaptation of an enzyme in the thermolysin family. Proteins: Structure, Function, and Bioinformatics 2006; Volum 62. ISSN 0887-3585.
  • Adekoya, Olayiwola; Willassen, Nils Peder; Sylte, Ingebrigt. Molecular insight into pseudolysin inhibition using the MM-PBSA and LIE methods. Journal of Structural Biology 2006; Volum 153. ISSN 1047-8477.s 129 - 144.
  • Ravna, Aina Westrheim; Sylte, Ingebrigt; Kristiansen, Kurt; Dahl, Svein G.. Putative drug binding conformations of monoamine transporters. Bioorganic & Medicinal Chemistry 2006; Volum 14. ISSN 0968-0896.
  • Adekoya, Olayiwola Adedotun; Willassen, Nils Peder; Sylte, Ingebrigt. The protein-protein interactions between SMPI and thermolysin studied by molecular dynamics and MM/PBSA calculations. Journal of Biomolecular Structure and Dynamics 2005; Volum 22 (5). ISSN 0739-1102.s 521 - 532.
  • Dahl, Svein Gunvald; Sylte, Ingebrigt. Molecular modelling of drug targets: The past, the present and the future. Basic & Clinical Pharmacology & Toxicology 2005; Volum 96. ISSN 1742-7835.s 151 - 155.
  • Lindstad, Rune I.; Sylte, Ingebrigt; Mikalsen, Svein O.; Seglen, Per O.; Berg, Eli; Winberg, Jan O.. Pancreatic trypsin activates human promatrix metalloproteinase-2. Journal of Molecular Biology (JMB) 2005; Volum 350. ISSN 0022-2836.s 682 - 698.
  • Hjerde, Erik; Dahl, Svein G.; Sylte, Ingebrigt. Atypical and typical antipsychotic drug interactions with the dopamine D2 receptor. European Journal of Medicinal Chemistry 2005; Volum 40. ISSN 0223-5234.
  • Lindstad, Rune I; Sylte, Ingebrigt; Mikalsen, S O; Seglen, P O; Berg, Eli; Winberg, Jan-Olof. Pancreatic trypsin activates human promatrix metal loproteinase-2. Journal of Molecular Biology (JMB) 2005; Volum 350. ISSN 0022-2836.s 682 - 698.
  • Våbenø, Jon; Nielsen, Carsten Uhd; Steffansen, Bente; Lejon, Tore Sigvard; Sylte, Ingebrigt; Jørgensen, Flemming Steen; Luthman, Kristina. Conformational restrictions in ligand binding to the human intestinal di-/tripeptide transporter: implications for design of hPEPT1 targeted prodrugs. Bioorganic & Medicinal Chemistry 2005; Volum 13. ISSN 0968-0896.s 1977 - 1988.
  • Dahl, Svein G.; Sylte, Ingebrigt; Ravna, Aina Westrheim. Structures and models of transporter proteins. Journal of Pharmacology and Experimental Therapeutics 2004; Volum 309 (3). ISSN 0022-3565.s 853 - 860.
  • Strzelczyk, Anna Agnieszka; Jaronczyk, Malgorzata; Chilmonczyk, Zdizlav; Mazurek, Pavel A; Chojnacka-Wojcik, Eva; Sylte, Ingebrigt. Intrinsic activity and comparative molecular dynamics of buspirone analogues at the 5-HT1A receptors. Biochemical Pharmacology 2004; Volum 67. ISSN 0006-2952.s 2219 - 2230.
  • Ravna, Aina Westrheim; Sylte, Ingebrigt; Dahl, Svein G.. Molecular model of the neural dopamine transporter. Journal of Computer-Aided Molecular Design 2003; Volum 17. ISSN 0920-654X.s 367 - 382.
  • Yang, Nannan; Mekonnen, Seble Merid; Solstad, Terese; Wikman, Mari; Kalaaji, manar; Sylte, Ingebrigt; Rekdal, Øystein. Enhanced tumor cell specificity by optimizing the relative position between aromatic and cationic residues in helical amphipathic peptides. 2003 ISBN 82-497-0155-0.
  • Ravna, Aina Westrheim; Sylte, Ingebrigt; Dahl, Svein G.. Molecular mechanisms of citalopram and cocaine interactions with the neurotransmitter transporter. Journal of Pharmacology and Experimental Therapeutics 2003; Volum 307 (1). ISSN 0022-3565.s 34 - 41.
  • Brandsdal, Bjørn Olav; Heimstad, Eldbjørg Sofie; Sylte, Ingebrigt; Smalås, Arne Oskar. Comparative Molecular Dynamics of Mesophilic and Psychrophilic Homologues Studied by 1.2 ns Simulations. Journal of Biomolecular Structure and Dynamics 1999; Volum 17. ISSN 0739-1102.s 493 - 506.s doi: 10.1080/07391102.1999.10508380.
  • Tollefsen, Knut-Erik; Cronin, Marc Timothy David; Evenseth, Linn; Firman, James W.; Iguchi, Taisen; Lalone, Carlie; Mellor, Claire; Sylte, Ingebrigt; Toyota, K.; Villeneuve, Daniel L.; Song, You. Endocrine Disruption in crustaceans – a “new” environmental challenge?. 20th Pollutant Responses in Marine Organism (PRIMO20) conference 2019-05-19 - 2019-05-22 2019.
  • Tollefsen, Knut Erik; Cronin, Marc Timothy David; Evenseth, Linn; Firman, James W.; Iguchi, Taisen; Lalone, Carlie; Mellor, Claire; Sylte, Ingebrigt; Toyota, K.; Villeneuve, Daniel L.; Song, You. AOP-informed chemical screening, prioritization and risk assessment of arthropod Endocrine Disruptors. SETAC workshop on Hight-Throughput Screening 2018-04-16 - 2018-04-18 2018.
  • Tollefsen, Knut Erik; Cronin, Marc Timothy David; Evensen, Øystein; Evenseth, Linn; Falciani, Francesco; Iguchi, Taisen; Lalone, Carlie; Li, Yang; Mellor, Claire; Perkins, Edward J.; Rundberget, Thomas; Salbu, Brit; Sylte, Ingebrigt; Villeneuve, Daniel L.; Vinas, N.; Song, You. AOP-informed assessment of Endocrine Disruption in freshwater crustaceans. 28th annual SETAC Europe Meeting 2018-05-13 - 2018-05-17 2018.
  • Song, You; Villeneuve, Daniel L.; Iguchi, Taisen; Rundberget, Thomas; Mellor, Claire; Cronin, Marc Timothy David; Evenseth, Linn; Sylte, Ingebrigt; Lalone, Carlie; Høgåsen, Tore; Falciani, Francesco; Garcia-Reyero, Natalia; Perkins, Edward J.; Evensen, Øystein; Xie, Li; Lyne, Fern; Gomes, Tania; Lillicrap, Adam David; Salbu, Brit; Tollefsen, Knut Erik. Development of invertebrate Adverse Outcome Pathways (AOPs) for mechanistically-based risk assessment. Nanjing Univeristy internal seminar 2017-04-23 - 2017.
  • Song, You; Villeneuve, Daniel L.; Iguchi, Taisen; Rundberget, Thomas; Mellor, Claire; Cronin, Marc Timothy David; Evenseth, Linn; Sylte, Ingebrigt; Lalone, Carlie; Hackermüller, Jörg; Høgåsen, Tore; Falciani, Francesco; Garcia-Reyero, Natalia; Perkins, Edward J.; Evensen, Øystein; Xie, Li; Lyne, Fern; Gomes, Tania; Lillicrap, Adam David; Salbu, Brit; Tollefsen, Knut Erik. Development of invertebrate Adverse Outcome Pathways (AOPs) for mechanistically-based risk assessment. International Symposium on Chemicals Risk Prediction and Management (ISCRPM-2017) 2017-04-25 - 2017.
  • Song, You; Villeneuve, Daniel L.; Iguchi, Taisen; Rodriguez-Sanchez, Neus; Rundberget, Thomas; Mellor, Claire; Cronin, Marc Timothy David; Evenseth, Linn; Sylte, Ingebrigt; Lalone, Carlie; Høgåsen, Tore; Falciani, Francesco; Garcia-Reyero, Natalia; Perkins, Edward J.; Evensen, Øystein; Xie, Li; Lyne, Fern; Gomes, Tania; Lillicrap, Adam David; Salbu, Brit; Tollefsen, Knut Erik. Development of invertebrate Adverse Outcome Pathways (AOPs) for mechanistically-based risk assessment. China’s 4th Symposium on Ecotoxicology 2017-04-24 - 2017.
  • Sæther, Thomas; Moldes-Anaya, Angel; Tungen, Jørn Eivind; Vik, Anders; Paulsen, Steinar M; Sylte, Ingebrigt; Hansen, Trond Vidar; Nebb, Hilde Irene. Anti-diabetic activity from marine lipids: new anti-diabetic drugs. Throne Holst Symposium 2016-05-19 - 2016-05-19 2016.
  • Sæther, Thomas; Moldes-Anaya, Angel; Tungen, Jørn Eivind; Vik, Anders; Paulsen, Steinar Martin; Sylte, Ingebrigt; Hansen, Trond Vidar; Nebb, Hilde Irene. Anti-diabetic activity from marine lipids: new anti-diabetic drugs. EMBO Conference on Nuclear Receptors 2015-09-24 - 2015-09-28 2015.
  • Mortensen, Åse-Karen; Jenssen, Bjørn Munro; Gabrielsen, Geir W.; Sylte, Ingebrigt; Heimstad, Eldbjørg Sofie. Competitive binding of persistent organic pollutants to the thyroid hormone transport protein transthyretin in Glaucous gull (Larus hypoerboreus). 2015.
  • Song, You; Cronin, Mark T.; Evensen, Øystein; Falciani, Francesco; Garcia-Reyero, Natalia; Høgåsen, Tore; Iguchi, Taisen; Langford, Katherine; Lalone, Carlie; Lillicrap, Adam David; Mellor, Claire; Perkins, Edward; Petersen, Karina; Salbu, Brit; Sylte, Ingebrigt; Thomas, Kevin V; Tollefsen, Knut Erik. EDRISK: Development of adverse outcome pathways for endocrine disruption in Daphnia magna. Scientific seminar at The Norwegian Environmental agency 2014-03-11 - 2014-03-11 2014.
  • Song, You; Cronin, Mark T.; Evensen, Øystein; Falciani, Francesco; Høgåsen, Tore; Iguchi, Taisen; Lalone, Carlie; Lillicrap, Adam David; Petersen, Karina; Perkins, Edward; Rundberget, Thomas; Salbu, Brit; Sylte, Ingebrigt; Thomas, Kevin V; Garcia-Reyero, Natalia; Tollefsen, Knut Erik. Development of adverse outcome pathways for endocrine disruption in Daphnia magna. SETAC Europe 24th annual meeting 2014-05-11 - 2014-05-15 2014.
  • Song, You; Antczak, Philipp; Cronin, Mark T.; Evenseth, Linn; Evensen, Øystein; Falciani, Francesco; Høgåsen, Tore; Iguchi, Taisen; Lalone, Carlie; Mellor, Claire; Perkins, Edward; Salbu, Brit; Sylte, Ingebrigt; Garcia-Reyero, Natalia; Villeneuve, Daniel; Tollefsen, Knut Erik. Development of adverse outcome pathways for endocrine disruption in Daphnia magna. SETAC North America Annual Meeting 2014-11-09 - 2014-11-13 2014.
  • Sylte, Ingebrigt; Sager, Georg. En pionerforsker. Ottar 2013 (297). ISSN 0030-6703.s 27 - 31.
  • Ravna, Aina Westrheim; Sylte, Ingebrigt. Drug design på data'n. Ottar 2013 (297). ISSN 0030-6703.s 22 - 26.
  • Tarpley, Reid S.; Adekoya, Olayiwola; Sylte, Ingebrigt; Odunuga, Odutayo O.. Large-scale expression and purification of active pseudolysin in Escherichia coli. The FASEB Journal 2013; Volum 27. ISSN 0892-6638.
  • Baglo, Yan; Gabrielsen, Mari; Sylte, Ingebrigt; Gederaas, Odrun Arna. Homology Modeling of Human <gamma>-Butyric Acid Transporters and the Binding of Pro-drugs 5-Aminolevulinic Acid and Methyl Aminolevulinic Acid used in Photodynamic Therapy. 15th Congress of the European Society for Photobiology 2013-09-02 - 2013-09-06 2013.
  • Baglo, Yan; Gabrielsen, Mari; Sylte, Ingebrigt; Gederaas, Odrun Arna. Homology modelling of human GABA transporters and the binding of prodrugs 5-aminolevulinic acid and its methyl ester used in photodynamic therapy. 3. Biostruct årsmøte, UiT 2012-08-30 - 2012-09-02 2012.
  • Gabrielsen, Mari; Sylte, Ingebrigt; Dahl, Svein G.; Ravna, aina westrheim. A short update on the structure of drug binding sites on neurotransmitter transporters. BMC Research Notes 2011; Volum 4. ISSN 1756-0500.s doi: 10.1186/1756-0500-4-559.
  • Baglo, Yan; Gabrielsen, Mari; Sylte, Ingebrigt. Homology modelling av GABA transporter: analyse av prodrug ALA og MAL uptak. NOFFOF årsmøte 2011 2011-11-18 - 2011.
  • Adekoya, Olayiwola; Sylte, Ingebrigt. Molecular interactions of ABT and matrix metalloproteinases. The FEBS Journal 2011; Volum 278. ISSN 1742-464X.s 322 - 322.
  • Chilmonczyk, Zdzislaw; Kossakowski, Jerzy; Walory, Jaroslaw; Koronkiewicz, Miroslawa; Sylte, Ingebrigt; Nowak, Gabriel; Bojarski, Andrezej J. Influence of new high affinity serotonin transporter ligands on cellular cAMP levels. Pharmacological Reports 2011; Volum 63 (2). ISSN 1734-1140.s 565 - 565.
  • Sjøli, Stian; Adekoya, Olayiwola; Jiang, Yang; Akselsen, O; Hansen, VT; Svineng, Gunbjørg; Sylte, Ingebrigt; Winberg, Jan-Olof. Novel Inhibitors of Matrix Metalloprotease-9 and-14. The FEBS Journal 2010; Volum 277. ISSN 1742-464X.s 265 - 265.
  • Wuxiuer, Yimingjiang; Cols, N; Gonzalez-Duarte, R; Ladenstein, R; Sylte, Ingebrigt; Winberg, Jan-Olof. Kinetic characterization of the Drosophila lebanonensis ADH T114V mutant. The FEBS Journal 2010; Volum 277. ISSN 1742-464X.s 265 - 265.
  • Chilmonczyk, Zdizlav; Jaronczyk, Malgorzata; Mazurek, AP; Sylte, Ingebrigt; Ravna, aina westrheim. Molecular targets for new antidepressant drugs. Pharmacological Reports 2008; Volum 60. ISSN 1734-1140.s 260 - 260.
  • Orhan, I; Khan, Mahmud Tareq Hassan; Aslan, S; Kartal, M; Sener, B; Sylte, Ingebrigt. Molecular docking studies on the alkaloid (+)-buxabenzamidienine from Buxus sempervirens L. with anticholinesterase effect. Planta Medica 2008; Volum 74 (9). ISSN 0032-0943.s 1166 - 1167.
  • Sylte, Ingebrigt. Molekylære mekanismer i jakten på nye legemidler - utvikling av nye antidepressive legemidler. Onsdagsmøte 2007-11-07 - 2007.
  • Sylte, Ingebrigt. Structural visualization of molecular drug targets in the CNS. Conference on Imaging in Neuroscience 2007-04-26 - 2007-04-27 2007.
  • Sylte, Ingebrigt. Structural biology and visualization of drug targets. Workshop on Molecular Imaging 2007-04-27 - 2007.
  • Jaronczyk, Malgorzata; Chilmonczyk, Zdizlav; Mazurek, AP; Dybala, M; Ravna, aina westrheim; Kristiansen, kurt; Sylte, Ingebrigt. Molecular mechanism of selective serotonin reuptake inhibitors (SSRI's) interactions with serotonin transporter. Journal of Peptide Science 2006; Volum 12. ISSN 1075-2617.s 186 - 186.
  • Gani, Osman A.B.S.M.; Sylte, Ingebrigt. The effect of E-Z isomerization of docosahexaeonic acid (DHA) double bonds on binding to nuclear receptors. Docking and scoring in structure guided drug design. 2006-04-05 - 2006-04-07 2006.
  • Gani, Osman A.B.S.M.; Sylte, Ingebrigt. Molecular recognition of fatty acids by PPAR-alpha. Structure-based Drug Design 2006-06-14 - 2006-06-16 2006.
  • Khan, Mahmud Tareq Hassan; Adekoya, Olayiwola Adedotun; Sylte, Ingebrigt. Sequence analysis of the assigned members of the M4 family of the peptidases compared to thermolysin, the prototype of the clan. Bioforum 2006 2006-06-07 - 2006-06-09 2006.
  • Jaronczyk, Malgorzata; Chilmonczyk, Zdizlav; Mazurek, AP; Dybala, M; Ravna, aina westrheim; Kristiansen, kurt; Sylte, Ingebrigt. Molecular mechanism of selective serotonin reuptake inhibitors (SSRI's)interactions with serotonin transporter. 29th European Peptide Symposium 2006-09-03 - 2006-09-08 2006.
  • Adekoya, Olayiwola Adedotun; Dahl, Svein G.; Gabrielsen, Mari; Gani, Osman A.B.S.M.; Khan, Mahmud Tareq Hassan; Kristiansen, kurt; Sylte, Ingebrigt; Ravna, aina westrheim; Wuxiuer, Y; Sandberg, LS. The molecular modelling group. Open day 2006. PhD-school in Molecular and Structural Biology 2006-11-15 - 2006.
  • Khan, Mahmud Tareq Hassan; Adekoya, Olayiwola Adedotun; Lorentzen, marit sjo; Willassen, Nils Peder; Smalås, Arne Oskar; Sylte, Ingebrigt. Molecular features and inhibition of the thermolysin family of enzymes. Open day 2006. PhD-school in Molecular and Structural Biology 2006-11-15 - 2006.
  • Gani, Osman A.B.S.M.; Sylte, Ingebrigt. Molecular recognition of fatty acids by PPAR-alpha. Open day 2006. PhD-school in Molecular and Structural Biology 2006-11-15 - 2006.
  • Khan, Mahmud Tareq Hassan; Sylte, Ingebrigt. Structural bioinformatics in the discovery of novel drugs. 9th Eurasis Conference on Chemical Sciences 2006-09-09 - 2006-09-13 2006.
  • Adekoya, Olayiwola Adedotun; Helland, Ronny; Willassen, Nils Peder; Sylte, Ingebrigt. Structural determinants for a cold adapted enzyme in the thermolysin family. The Norwegian Biochemical Society 41st Contact meeting 2005-01-13 - 2005-01-16 2005.
  • Ghani, Osman A.b.s.m; Adekoya, Olayiwola; Giuratob, L; Guccione, S; Winberg, Jan-Olof; Sylte, Ingebrigt. The catalytic mechanisms of short-chain dehydrogenases/ reductases. Horizons in Molecular Biology Decoding Nature: Hierarchy of Interactions, 2nd International PhD Student Symposium 2005-03-01 - 2005-03-02 2005.
  • Ghani, Osman A.b.s.m; Adekoya, Olayiwola; Giuratob, L; Guccione, S; Winberg, Jan-Olof; Sylte, Ingebrigt. The catalytic mechanisms of short-chain dehydrogenases/ reductases. NBS kontaktmøte 2005-01-13 - 2005-01-16 2005.
  • Lindstad, Rune I; Sylte, Ingebrigt; Mikalsen, S O; Berg, Eli; Winberg, Jan-Olof. Pancreatic trypsin activates human promatrix metalloproteinase-2. NBS kontaktmøte 2005-01-13 - 2005-01-16 2005.
  • Strzelczyk, Anna Agnieszka; Jaronczyk, Malgorzata; Chilmonczyk, Zdizlav; Chojnacka-Wojcik, Eva; Sylte, Ingebrigt. The 5HT1A and 5HT2A serotonin receptors interactions with methylated buspirone analogues. The international conference sequence-structure-functions relationships. Thoretical and experimental approaches 2005-04-06 - 2005-04-10 2005.
  • Våbenø, Jon; Nielsen, Carsten Uhd; Ingebrigtsen, Truls Erik; Lejon, Tore Sigvard; Sylte, Ingebrigt; Jørgensen, Flemming Steen; Steffansen, Bente; Luthman, Kristina. Ketomethylene Based Dipeptidomimetics as Pro-Moieties for hPEPT1 Targeted Prodrugs. XVIII´th International Symposium on Medicinal Chemistry 2004-08-15 - 2004-08-19 2004.
  • Loennechen, thrina; Lysaa, Roy A; Giverhaug, trude; Sylte, Ingebrigt; Mathisen, L-E; Aarbakke, Jarle. Nye styringsverktøy for tiopuriner i leukemi og transplantasjonsbehandling. Tidsskrift for Den norske legeforening 2002. ISSN 0029-2001.s 1107 - 1110.
  • Helland, Ronny; Adekoya, Olayiwola; Mekonnen, Seble Merid; Gjellesvik, Dag Rune; Edvardsen, Øyvind; Høgda, Kjell Arild; Grøttum, Karl Johan; Sylte, Ingebrigt; Smalås, Arne Oskar; Willassen, Nils Peder. Determination of Molecular Descriptors from Analysis of Sequence and Genome Data. Bioinformatics 2002 2002-04-04 - 2002-04-07 2002.
  • Helland, Ronny; Adekoya, Olayiwola; Mekonnen, Seble Merid; Gjellesvik, Dag Rune; Edvardsen, Øyvind; Høgda, Kjell Arild; Grøttum, Karl Johan; Sylte, Ingebrigt; Smalås, Arne Oskar; Willassen, Nils Peder. Determination of Molecular Descriptors from Analysis of Sequence and Genome Data. Functional Genomics in Tromsø 2001-10-17 - 2001-10-18 2001.
  • Brandsdal, Bjørn Olav; Helland, Ronny; Sylte, Ingebrigt; Otlewski, J.; Smalås, Arne Oskar. Protein-protein recognition. Talking Proteins: An EMBO workhsop on sequence analysis, modelling and simulation 1998-09-01 - 1998.
    • Look at all works in CRIStin →

    Research interests

    Receptors and transporters in the CNS as drug targets

    Molecular mechanisms and inhibition of bacterial and human zinc proteases

    Teaching

    Pharmacology


    Member of research group

    Molekylær farmakologi og toksikologi   Norsk innhold Molecular Pharmacology and Toxicology   English content