Bilde av Ytrehus, Kirsti
Bilde av Ytrehus, Kirsti
Department of Medical Biology kirsti.ytrehus@uit.no +4777644781 95106332 Tromsø MH L7.225B

Kirsti Ytrehus


Professor

Job description

Medical Physiology and Cardiac Research


  • Aleksander Tank Falck, Bjarte Aarmo Lund, David Johansen, trine Lund, Kirsti Ytrehus :
    The Ambivalence of Connexin43 Gap Peptides in Cardioprotection of the Isolated Heart against Ischemic Injury
    International Journal of Molecular Sciences 2022 ARKIV / DOI
  • Cinzia Perrino, Péter Ferdinandy, Hans Erik Bøtker, Bianca J. J. M Brundel, Peter Collins, Sean M Davidson et al.:
    Improving translational research in sex-specific effects of comorbidities and risk factors in ischaemic heart disease and cardioprotection: Position paper and recommendations of the ESC Working Group on Cellular Biology of the Heart
    Cardiovascular Research (CVR) 2021 ARKIV / DOI
  • Kirsti Ytrehus, Stian Ludvigsen, Costantino Mancusi, Eva Gerdts, Giovanni de Simone :
    Heart Angiotensin-Converting Enzyme and Angiotensin-Converting Enzyme 2 Gene Expression Associated With Male Sex and Salt-Sensitive Hypertension in the Dahl Rat
    Frontiers in Physiology 2021 ARKIV / DOI
  • Lucia Kindernay, Veronika Farkasova, Jan Neckar, Jaroslav Hrdlicka, Kirsti Ytrehus, Tanya Ravingerova :
    Impact of maturation on myocardial response to ischemia and the effectiveness of remote preconditioning in male rats
    International Journal of Molecular Sciences 2021 ARKIV / DOI
  • Ioanna Andreadou, Rainer Schulz, Andreas Papapetropoulos, Belma Turan, Kirsti Ytrehus, Peter Ferdinandy et al.:
    The role of mitochondrial reactive oxygen species, NO and H2S in ischaemia/reperfusion injury and cardioprotection
    Journal of Cellular and Molecular Medicine 2020 ARKIV / DOI
  • Rosalinda Madonna, Linda W. Van Laake, Hans Erik Bøtker, Sean M. Davidson, Raffaele De Caterina, Felix B. Engel et al.:
    ESC working group on cellular biology of the heart: Position paper for Cardiovascular Research: Tissue engineering strategies combined with cell therapies for cardiac repair in ischaemic heart disease and heart failure
    Cardiovascular Research (CVR) 2019 ARKIV / DOI
  • Henrik Brovold, Trine Lund, Dmitri Svistounov, Marit Dahl Solbu, Trond Geir Jenssen, Kirsti Ytrehus et al.:
    Crystallized but not soluble uric acid elicits pro-inflammatory response in short-term whole blood cultures from healthy men
    Scientific Reports 2019 ARKIV / DOI
  • Marisol Ruiz-Meana, Kerstin Boengler, David Garcia-Dorado, Derek John Hausenloy, Tuuli Kaambre, Georgios Kararigas et al.:
    Ageing, sex and cardioprotection.
    British Journal of Pharmacology 20. December 2019 DOI
  • Neoma Tove Boardman, Aleksander Tank Falck, Trine Lund, Xi Chu, Armas Maria Montserrat Martin, Jon Viljar Norvik et al.:
    Human concentrations of uric acid scavenges adaptive and maladaptive ROS in isolated rat hearts subjected to ischemic stress
    Canadian Journal of Physiology and Pharmacology 13. September 2019 ARKIV / DOI
  • Joost Petrus Geradus Sluijter, Sean Michael Davidson, Chantal M Boulanger, Edit Iren Buzas, Dominique P.V. De Kleijn, Felix Benedikt Engel et al.:
    Extracellular vesicles in diagnostics and therapy of the ischaemic heart: Position Paper from the Working Group on Cellular Biology of the Heart of the European Society of Cardiology
    Cardiovascular Research (CVR) 2018 ARKIV / DOI
  • Stian Ludvigsen, Costantino Mancusi, Simon Kildal, Giovanni de Simone, Eva Gerdts, Kirsti Ytrehus :
    Cardiac adaptation to hypertension in adult female Dahl salt-sensitive rats is dependent on ovarian function, but loss of ovarian function does not predict early maladaptation
    Physiological Reports 2018 ARKIV / DOI
  • Kirsti Ytrehus, Jean-Sébastien Hulot, Cinzia Perrino, Gabriele Giacomo Schiattarella, Rosalinda Madonna :
    Perivascular fibrosis and the microvasculature of the heart. Still hidden secrets of pathophysiology?
    Vascular pharmacology 2018 DOI
  • Cinzia Perrino, Albert-Laszló Barabási, Gianluigi Condorelli, Sean Michael Davidson, Leon De Windt, Stefanie Dimmeler et al.:
    Epigenomic and transcriptomic approaches in the post-genomic era: Path to novel targets for diagnosis and therapy of the ischaemic heart? Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart
    Cardiovascular Research (CVR) 2017 ARKIV / DOI
  • Jon Viljar Norvik, Henrik Schirmer, Kirsti Ytrehus, Hilde-Merete Storhaug, Trond Geir Jenssen, Bjørn Odvar Eriksen et al.:
    Uric acid predicts mortality and ischaemic stroke in subjects with diastolic dysfunction: the Tromsø Study 1994-2013
    ESC Heart Failure 2017 ARKIV / DOI
  • Derek J. Hausenloy, David Garcia-Dorado, Hans Erik Bøtker, Sean M. Davidson, James Downey, Felix B. Engel et al.:
    Novel targets and future strategies for acute cardioprotection: Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart
    Cardiovascular Research (CVR) 2017 DOI
  • Jon Viljar Norvik, Henrik Schirmer, Kirsti Ytrehus, Trond Geir Jenssen, Svetlana Zykova, Anne Elise Eggen et al.:
    Low adiponectin is associated with diastolic dysfunction in women: A cross-sectional study from the Tromsø Study
    BMC Cardiovascular Disorders 2017 ARKIV / DOI
  • Wahida Salma, Veronika Franeková, trine Lund, Anje Christina Höper, Stian Ludvigsen, Jim Lund et al.:
    Dietary Calanus oil antagonizes angiotensin II-induced hypertension and tissue wasting in diet-induced obese mice
    Prostaglandins, Leukotrienes and Essential Fatty Acids 2016 DOI
  • Marte Bliksøen, Lars Henrik Mariero, May-Kristin Torp, Anton Baysa, Kirsti Ytrehus, Fred Haugen et al.:
    Extracellular mtDNA activates NF-κB via toll-like receptor 9 and induces cell death in cardiomyocytes
    Basic Research in Cardiology 2016 DOI
  • Jon Viljar Norvik, Hilde-Merete Storhaug, Kirsti Ytrehus, Trond Geir Jenssen, Svetlana Zykova, Bjørn Odvar Eriksen et al.:
    Overweight modifies the longitudinal association between uric acid and some components of the metabolic syndrome: The Tromsø Study
    BMC Cardiovascular Disorders 2016 ARKIV / DOI
  • Rosalinda Madonna, Linda W. Van Laake, Sean M. Davidson, Felix B. Engel, Derek J. Hausenloy, Sandrine Lecour et al.:
    Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: Cell-based therapies for myocardial repair and regeneration in ischemic heart disease and heart failure
    European Heart Journal 2016 DOI
  • Nils Thomas Songstad, Knut-Helge Kaspersen, Anne Dragøy Hafstad, Purusotam Basnet, Kirsti Ytrehus, Ganesh Acharya :
    Effects of high intensity interval training on pregnant rats, and the placenta, heart and liver of their fetuses
    PLOS ONE 13. November 2015 ARKIV / DOI
  • Nils Thomas Songstad, David Johansen, Ole-Jakob How, Per Ivar Kaaresen, Kirsti Ytrehus, Ganesh Acharya :
    Effect of transverse aortic constriction on cardiac structure, function and gene expression in pregnant rats
    PLOS ONE 2014 ARKIV / DOI
  • Nils Thomas Songstad, Maria Serrano, Vasilis Sitras, David Johansen, Kirsti Ytrehus, Ganesh Acharya :
    Coronary flow reserve in pregnant rats with increased left ventricular afterload
    PLOS ONE 2014 FULLTEKST / ARKIV / DOI
  • Thor Allan Stenberg, Anders Benjamin Kildal, Espen Sanden, Ole-Jakob How, Martin Hagve, Kirsti Ytrehus et al.:
    The acute phase of experimental cardiogenic shock is counteracted by microcirculatory and mitochondrial adaptations
    PLOS ONE 2014 ARKIV / DOI
  • Stig Eggen Hermansen, trine Lund, Trine Kalstad, Kirsti Ytrehus, Truls Myrmel :
    Adrenomedullin augments the angiogenic potential of late outgrowth endothelial progenitor cells
    American Journal of Physiology - Cell Physiology 2011 DOI
  • David Johansen, Véronique Cruciani, Rune Sundset, Kirsti Ytrehus, Svein-Ole Mikalsen :
    Ischemia Induces Closure of Gap Junctional Channels and Opening of Hemichannels in Heart-derived Cells and Tissue
    Cellular Physiology and Biochemistry 2011 DOI
  • Terje Larsen, Kirsti Ytrehus :
    Hjertets patofysiologi
    Gyldendal Norsk Forlag A/S 2011
  • Mohammad Belal Aljabri, Nils Thomas Songstad, trine Lund, Maria Serrano, Thomas Vennø Andreasen, Samer Al-Saad et al.:
    Pregnancy protects against antiangiogenic and fibrogenic effects of angiotensin II in rat hearts
    Acta Physiologica 2011 DOI
  • Mohammad Belal Aljabri, trine Lund, Anje Christina Høper, thomas vennØ Andreasen, Samer Al-Saad, Sigurd Lindal et al.:
    Gene Expression, Function and Ischemia Tolerance in Male and Female Rat Hearts After Sub-Toxic Levels of Angiotensin II
    Cardiovascular Toxicology 2011 ARKIV / DOI
  • David Johansen, Espen Sanden, Martin Hagve, Xi Chu, Rune Sundset, Kirsti Ytrehus :
    Heptanol triggers cardioprotection via mitochondrial mechanisms and mitochondrial potassium channel opening in rat hearts
    Acta Physiologica 2011 DOI
  • Øyvind Jakobsen, Tor Steensrud, Kirsti Ytrehus, Dag Glen Sørlie :
    Adenosine protects against hypoxic injury at hypothermia in guinea pig papillary muscles
    Scandinavian Cardiovascular Journal 2010 DOI
  • Trine Lund, Stig Eggen Hermansen, Thomas Vennø Andreasen, Jan Ole Olsen, Bjarne Østerud, Truls Myrmel et al.:
    Shear stress regulates inflammatory and thrombogenic gene transcripts in cultured human endothelial progenitor cells
    Thrombosis and Haemostasis 2010 DOI
  • Mohammad Belal Aljabri, trine Lund, Anje Christina Høper, Thomas Vennø Andreasen, Samer Al-Saad, Sigurd Lindal et al.:
    Gene expression, function and ischemia tolerance in male and female rat hearts after sub-toxic levels of Angiotensin II
    Cardiovascular Toxicology 2010 ARKIV / DOI
  • Terje Larsen, Terje Steigen, Kirsti Ytrehus :
    Hjertets patofysiologi
    Gyldendal Akademisk 2019
  • Kirsti Ytrehus, Neoma Tove Boardman, trine Lund, Svetlana Zykova, Trond Geir Jenssen :
    The uric acid paradox, a confounder in cardiovascular research and experimental studies of cardioprotection
    Conditioning Medicine 2019
  • Jon Viljar Norvik, Marit Dahl Solbu, Kirsti Ytrehus :
    Uric acid and adiponectin in cardiovascular disease
    2017
  • Kirsti Ytrehus, Terje Larsen, Geir Arve Christensen, Kåre-Olav Stensløkken, Finn Olav Levy :
    In memory of Guro Valen (1960-2014)
    Journal of Molecular and Cellular Cardiology 2015 DOI
  • Kirsti Ytrehus :
    Medisinske professorer, antall og alder
    LVS-info 18. December 2014
  • Kirsti Ytrehus :
    Kjære medlemmer!
    LVS-info 07. April 2014
  • Kirsti Ytrehus :
    Spesialist-PhD, et tankeeksperiment
    LVS-info 27. August 2014
  • Kirsti Ytrehus :
    Kjære medlemmer
    LVS-info 18. December 2014
  • Kirsti Ytrehus :
    Kjære kollegaer!
    LVS-info 27. August 2014
  • Kirsti Ytrehus, Liv Ariane Augestad, Tor-Arne Hagve, Espen Saxhaug Kristoffersen, Siv Kvernmo, Anna Middelfart et al.:
    Satsingen på medisinsk forskning kan bli svekket
    Dagens medisin 10. November 2014
  • Wahida Salma, Anje Christina Höper, trine Lund, Stian Ludvigsen, Kirsti Ytrehus, Ellen Aasum et al.:
    Dietary supply with Calanus oil antagonizes angiotensin IIinduced hypertension, cardiac hypertrophy and cachexia in obese mice
    2013
  • Nils Thomas Songstad, David Johansen, Ole-Jakob How, Kirsti Ytrehus, Ganesh Acharya :
    Effect of chronic pressure load on heart structure and function in pregnant rats
    2012
  • Mohammad Belal Aljabri, Kirsti Ytrehus :
    Angiotensin II and heart remodelling. Role of ischemia, gender and pregnancy
    2011
  • David Johansen, Espen Sanden, Xi Chu, Rune Sundset, Kirsti Ytrehus :
    Heptanol triggers cardio protection via mitochondrial potassium channels and not by gap junction uncoupling
    Cardiovascular Research (CVR) 2010
  • Stig eggen Hermansen, trine Lund, Kirsti Ytrehus, truls Myrmel :
    Adrenomedullin enhance proliferation and angiogenetic potential of late outgrowth endothelial progenitor cells
    2009
  • trine Lund, Margareth Bergesen Hals, Ruth H Paulssen, Kirsti Ytrehus :
    Increased gene expression diversity between female and male hearts after transverse aortic constriction (TAC)
    2009
  • trine Lund, Margareth Bergesen Hals, Ruth H Paulssen, Kirsti Ytrehus :
    Increased gene expression diversity between female and male mice hearts after transverse aortic constriction (TAC)
    2009

  • The 50 latest publications is shown on this page. See all publications in Cristin here →


    Research interests

    Cardiovascular physiology

    Myocardial infarction and myocardial protection

    The role of reactive oxygen species in cardiovascular physiology and pathophysiology

    Role of gender in heart disease



    CV

    Born in 1953. Mother of 3

     

    Education

    Univ of Oslo, Faculty of Math and Nat Sciences and Faculty of Medicine

    Cand. Med. 1980

    University of Tromsoe, Faculty of Medicine

    Dr. Med.1988:

                Thesis title Oxygen radicals and myocardial injury

     

    Appointments

    Clinical medicine:

    Internship and part time positions, 1981- 1992

     

    Academic positions:

    Research fellow University of Tromsoe, Institute for Medical Biology 1982 - 87

    Assistant professor University of Tromsoe 1987 - 1994

    Guest researcher/ visiting University of South Alabama, Dept of Physiology 1994-95

    Professor University of Bergen, Dept of Anatomy and Cell Biology 1995-96

    Guest researcher National Institute of Aging, National Institute of Health, Lab of Cardiovasc Sciences 2001-2002

    Professor Dept of Medical Biology, University of Tromsoe 1994 -1995 and 1996 - present

    Guest professor Cardiovascular division, Kings College Hospital, University of London