Kirsti Ytrehus
Professor
Job description
Medical Physiology and Cardiac Research
Aleksander Tank Falck,
Bjarte Aarmo Lund,
David Johansen,
trine Lund,
Kirsti Ytrehus
:
The Ambivalence of Connexin43 Gap Peptides in Cardioprotection of the Isolated Heart against Ischemic Injury
Cinzia Perrino,
Péter Ferdinandy,
Hans Erik Bøtker,
Bianca J. J. M Brundel,
Peter Collins,
Sean M Davidson
et al.:
Improving translational research in sex-specific effects of comorbidities and risk factors in ischaemic heart disease and cardioprotection: Position paper and recommendations of the ESC Working Group on Cellular Biology of the Heart
Kirsti Ytrehus,
Stian Ludvigsen,
Costantino Mancusi,
Eva Gerdts,
Giovanni de Simone
:
Heart Angiotensin-Converting Enzyme and Angiotensin-Converting Enzyme 2 Gene Expression Associated With Male Sex and Salt-Sensitive Hypertension in the Dahl Rat
Lucia Kindernay,
Veronika Farkasova,
Jan Neckar,
Jaroslav Hrdlicka,
Kirsti Ytrehus,
Tanya Ravingerova
:
Impact of maturation on myocardial response to ischemia and the effectiveness of remote preconditioning in male rats
Ioanna Andreadou,
Rainer Schulz,
Andreas Papapetropoulos,
Belma Turan,
Kirsti Ytrehus,
Peter Ferdinandy
et al.:
The role of mitochondrial reactive oxygen species, NO and H2S in ischaemia/reperfusion injury and cardioprotection
Rosalinda Madonna,
Linda W. Van Laake,
Hans Erik Bøtker,
Sean M. Davidson,
Raffaele De Caterina,
Felix B. Engel
et al.:
ESC working group on cellular biology of the heart: Position paper for Cardiovascular Research: Tissue engineering strategies combined with cell therapies for cardiac repair in ischaemic heart disease and heart failure
Henrik Brovold,
Trine Lund,
Dmitri Svistounov,
Marit Dahl Solbu,
Trond Geir Jenssen,
Kirsti Ytrehus
et al.:
Crystallized but not soluble uric acid elicits pro-inflammatory response in short-term whole blood cultures from healthy men
Marisol Ruiz-Meana,
Kerstin Boengler,
David Garcia-Dorado,
Derek John Hausenloy,
Tuuli Kaambre,
Georgios Kararigas
et al.:
Ageing, sex and cardioprotection.
British Journal of Pharmacology 20. December 2019 DOI
Neoma Tove Boardman,
Aleksander Tank Falck,
Trine Lund,
Xi Chu,
Armas Maria Montserrat Martin,
Jon Viljar Norvik
et al.:
Human concentrations of uric acid scavenges adaptive and maladaptive ROS in isolated rat hearts subjected to ischemic stress
Joost Petrus Geradus Sluijter,
Sean Michael Davidson,
Chantal M Boulanger,
Edit Iren Buzas,
Dominique P.V. De Kleijn,
Felix Benedikt Engel
et al.:
Extracellular vesicles in diagnostics and therapy of the ischaemic heart: Position Paper from the Working Group on Cellular Biology of the Heart of the European Society of Cardiology
Stian Ludvigsen,
Costantino Mancusi,
Simon Kildal,
Giovanni de Simone,
Eva Gerdts,
Kirsti Ytrehus
:
Cardiac adaptation to hypertension in adult female Dahl salt-sensitive rats is dependent on ovarian function, but loss of ovarian function does not predict early maladaptation
Kirsti Ytrehus,
Jean-Sébastien Hulot,
Cinzia Perrino,
Gabriele Giacomo Schiattarella,
Rosalinda Madonna
:
Perivascular fibrosis and the microvasculature of the heart. Still hidden secrets of pathophysiology?
Vascular pharmacology 2018 DOI
Cinzia Perrino,
Albert-Laszló Barabási,
Gianluigi Condorelli,
Sean Michael Davidson,
Leon De Windt,
Stefanie Dimmeler
et al.:
Epigenomic and transcriptomic approaches in the post-genomic era: Path to novel targets for diagnosis and therapy of the ischaemic heart? Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart
Jon Viljar Norvik,
Henrik Schirmer,
Kirsti Ytrehus,
Hilde-Merete Storhaug,
Trond Geir Jenssen,
Bjørn Odvar Eriksen
et al.:
Uric acid predicts mortality and ischaemic stroke in subjects with diastolic dysfunction: the Tromsø Study 1994-2013
Derek J. Hausenloy,
David Garcia-Dorado,
Hans Erik Bøtker,
Sean M. Davidson,
James Downey,
Felix B. Engel
et al.:
Novel targets and future strategies for acute cardioprotection: Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart
Cardiovascular Research (CVR) 2017 DOI
Jon Viljar Norvik,
Henrik Schirmer,
Kirsti Ytrehus,
Trond Geir Jenssen,
Svetlana Zykova,
Anne Elise Eggen
et al.:
Low adiponectin is associated with diastolic dysfunction in women: A cross-sectional study from the Tromsø Study
Wahida Salma,
Veronika Franeková,
trine Lund,
Anje Christina Höper,
Stian Ludvigsen,
Jim Lund
et al.:
Dietary Calanus oil antagonizes angiotensin II-induced hypertension and tissue wasting in diet-induced obese mice
Prostaglandins, Leukotrienes and Essential Fatty Acids 2016 DOI
Marte Bliksøen,
Lars Henrik Mariero,
May-Kristin Torp,
Anton Baysa,
Kirsti Ytrehus,
Fred Haugen
et al.:
Extracellular mtDNA activates NF-κB via toll-like receptor 9 and induces cell death in cardiomyocytes
Basic Research in Cardiology 2016 DOI
Jon Viljar Norvik,
Hilde-Merete Storhaug,
Kirsti Ytrehus,
Trond Geir Jenssen,
Svetlana Zykova,
Bjørn Odvar Eriksen
et al.:
Overweight modifies the longitudinal association between uric acid and some components of the metabolic syndrome: The Tromsø Study
Rosalinda Madonna,
Linda W. Van Laake,
Sean M. Davidson,
Felix B. Engel,
Derek J. Hausenloy,
Sandrine Lecour
et al.:
Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: Cell-based therapies for myocardial repair and regeneration in ischemic heart disease and heart failure
European Heart Journal 2016 DOI
Nils Thomas Songstad,
Knut-Helge Kaspersen,
Anne Dragøy Hafstad,
Purusotam Basnet,
Kirsti Ytrehus,
Ganesh Acharya
:
Effects of high intensity interval training on pregnant rats, and the placenta, heart and liver of their fetuses
Nils Thomas Songstad,
David Johansen,
Ole-Jakob How,
Per Ivar Kaaresen,
Kirsti Ytrehus,
Ganesh Acharya
:
Effect of transverse aortic constriction on cardiac structure, function and gene expression in pregnant rats
Nils Thomas Songstad,
Maria Serrano,
Vasilis Sitras,
David Johansen,
Kirsti Ytrehus,
Ganesh Acharya
:
Coronary flow reserve in pregnant rats with increased left ventricular afterload
Thor Allan Stenberg,
Anders Benjamin Kildal,
Espen Sanden,
Ole-Jakob How,
Martin Hagve,
Kirsti Ytrehus
et al.:
The acute phase of experimental cardiogenic shock is counteracted by microcirculatory and mitochondrial adaptations
Stig Eggen Hermansen,
trine Lund,
Trine Kalstad,
Kirsti Ytrehus,
Truls Myrmel
:
Adrenomedullin augments the angiogenic potential of late outgrowth endothelial progenitor cells
American Journal of Physiology - Cell Physiology 2011 DOI
David Johansen,
Véronique Cruciani,
Rune Sundset,
Kirsti Ytrehus,
Svein-Ole Mikalsen
:
Ischemia Induces Closure of Gap Junctional Channels and Opening of Hemichannels in Heart-derived Cells and Tissue
Cellular Physiology and Biochemistry 2011 DOI
Terje Larsen,
Kirsti Ytrehus
:
Hjertets patofysiologi
Gyldendal Norsk Forlag A/S 2011
Mohammad Belal Aljabri,
Nils Thomas Songstad,
trine Lund,
Maria Serrano,
Thomas Vennø Andreasen,
Samer Al-Saad
et al.:
Pregnancy protects against antiangiogenic and fibrogenic effects of angiotensin II in rat hearts
Acta Physiologica 2011 DOI
Mohammad Belal Aljabri,
trine Lund,
Anje Christina Høper,
thomas vennØ Andreasen,
Samer Al-Saad,
Sigurd Lindal
et al.:
Gene Expression, Function and Ischemia Tolerance in Male and Female Rat Hearts After Sub-Toxic Levels of Angiotensin II
David Johansen,
Espen Sanden,
Martin Hagve,
Xi Chu,
Rune Sundset,
Kirsti Ytrehus
:
Heptanol triggers cardioprotection via mitochondrial mechanisms and mitochondrial potassium channel opening in rat hearts
Acta Physiologica 2011 DOI
Øyvind Jakobsen,
Tor Steensrud,
Kirsti Ytrehus,
Dag Glen Sørlie
:
Adenosine protects against hypoxic injury at hypothermia in guinea pig papillary muscles
Scandinavian Cardiovascular Journal 2010 DOI
Trine Lund,
Stig Eggen Hermansen,
Thomas Vennø Andreasen,
Jan Ole Olsen,
Bjarne Østerud,
Truls Myrmel
et al.:
Shear stress regulates inflammatory and thrombogenic gene transcripts in cultured human endothelial progenitor cells
Thrombosis and Haemostasis 2010 DOI
Mohammad Belal Aljabri,
trine Lund,
Anje Christina Høper,
Thomas Vennø Andreasen,
Samer Al-Saad,
Sigurd Lindal
et al.:
Gene expression, function and ischemia tolerance in male and female rat hearts after sub-toxic levels of Angiotensin II
Terje Larsen,
Terje Steigen,
Kirsti Ytrehus
:
Hjertets patofysiologi
Gyldendal Akademisk 2019
Kirsti Ytrehus,
Neoma Tove Boardman,
trine Lund,
Svetlana Zykova,
Trond Geir Jenssen
:
The uric acid paradox, a confounder in cardiovascular research and experimental studies of cardioprotection
Conditioning Medicine 2019
Jon Viljar Norvik,
Marit Dahl Solbu,
Kirsti Ytrehus
:
Uric acid and adiponectin in cardiovascular disease
2017
Kirsti Ytrehus,
Terje Larsen,
Geir Arve Christensen,
Kåre-Olav Stensløkken,
Finn Olav Levy
:
In memory of Guro Valen (1960-2014)
Journal of Molecular and Cellular Cardiology 2015 DOI
Kirsti Ytrehus
:
Medisinske professorer, antall og alder
LVS-info 18. December 2014
Kirsti Ytrehus
:
Kjære medlemmer!
LVS-info 07. April 2014
Kirsti Ytrehus
:
Spesialist-PhD, et tankeeksperiment
LVS-info 27. August 2014
Kirsti Ytrehus
:
Kjære medlemmer
LVS-info 18. December 2014
Kirsti Ytrehus
:
Kjære kollegaer!
LVS-info 27. August 2014
Kirsti Ytrehus,
Liv Ariane Augestad,
Tor-Arne Hagve,
Espen Saxhaug Kristoffersen,
Siv Kvernmo,
Anna Middelfart
et al.:
Satsingen på medisinsk forskning kan bli svekket
Dagens medisin 10. November 2014
Wahida Salma,
Anje Christina Höper,
trine Lund,
Stian Ludvigsen,
Kirsti Ytrehus,
Ellen Aasum
et al.:
Dietary supply with Calanus oil antagonizes angiotensin IIinduced hypertension, cardiac hypertrophy and cachexia in obese mice
2013
Nils Thomas Songstad,
David Johansen,
Ole-Jakob How,
Kirsti Ytrehus,
Ganesh Acharya
:
Effect of chronic pressure load on heart structure and function in pregnant rats
2012
Mohammad Belal Aljabri,
Kirsti Ytrehus
:
Angiotensin II and heart remodelling. Role of ischemia, gender and pregnancy
2011
David Johansen,
Espen Sanden,
Xi Chu,
Rune Sundset,
Kirsti Ytrehus
:
Heptanol triggers cardio protection via mitochondrial potassium channels and not by gap junction uncoupling
Cardiovascular Research (CVR) 2010
Stig eggen Hermansen,
trine Lund,
Kirsti Ytrehus,
truls Myrmel
:
Adrenomedullin enhance proliferation and angiogenetic potential of late outgrowth endothelial progenitor cells
2009
trine Lund,
Margareth Bergesen Hals,
Ruth H Paulssen,
Kirsti Ytrehus
:
Increased gene expression diversity between female and male hearts after transverse aortic constriction (TAC)
2009
trine Lund,
Margareth Bergesen Hals,
Ruth H Paulssen,
Kirsti Ytrehus
:
Increased gene expression diversity between female and male mice hearts after transverse aortic constriction (TAC)
2009
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Research interests
Cardiovascular physiology
Myocardial infarction and myocardial protection
The role of reactive oxygen species in cardiovascular physiology and pathophysiology
Role of gender in heart disease
Member of research group
CV
Born in 1953. Mother of 3
Education
Univ of Oslo, Faculty of Math and Nat Sciences and Faculty of Medicine
Cand. Med. 1980
University of Tromsoe, Faculty of Medicine
Dr. Med.1988:
Thesis title Oxygen radicals and myocardial injury
Appointments
Clinical medicine:
Internship and part time positions, 1981- 1992
Academic positions:
Research fellow University of Tromsoe, Institute for Medical Biology 1982 - 87
Assistant professor University of Tromsoe 1987 - 1994
Guest researcher/ visiting University of South Alabama, Dept of Physiology 1994-95
Professor University of Bergen, Dept of Anatomy and Cell Biology 1995-96
Guest researcher National Institute of Aging, National Institute of Health, Lab of Cardiovasc Sciences 2001-2002
Professor Dept of Medical Biology, University of Tromsoe 1994 -1995 and 1996 - present
Guest professor Cardiovascular division, Kings College Hospital, University of London