Trude Anderssen


Senior engineer

Job description

I am affiliated with the Natural Products and Medicinal Chemistry Research Group and teach at various chemistry-related laboratory courses for pharmacy students. I provide in-house training in HSE for new students/employees at the research group. I also assist on various research projects, including toxicity testing of synthesis products.


  • Manuel K Langer, Ataur Rahman, Hymonti Dey, Trude Anderssen, Hans-Matti Blencke, Tor Haug et al.:
    Investigation of tetrasubstituted heterocycles reveals hydantoins as a promising scaffold for development of novel antimicrobials with membranolytic properties
    European Journal of Medicinal Chemistry 2023 ARKIV / DOI
  • Susannah von Hofsten, Manuel K Langer, Katja Korelin, Synnøve Norvoll Magnussen, Dominik Ausbacher, Trude Anderssen et al.:
    Amphipathic barbiturates as marine product mimics with cytolytic and immunogenic effects on head and neck squamous cell carcinoma cell lines
    Frontiers in Pharmacology 30. March 2023 ARKIV / DOI
  • Manuel K Langer, Ataur Rahman, Hymonti Dey, Trude Anderssen, Francesco Zilioli, Tor Haug et al.:
    A concise SAR-analysis of antimicrobial cationic amphipathic barbiturates for an improved activity-toxicity profile
    European Journal of Medicinal Chemistry 2022 ARKIV / FULLTEKST / DATA / DOI
  • Hymonti Dey, Danijela Simonovic, Ingrid Sofie Norberg-Schulz Hagen, Terje Vasskog, Elizabeth G. Aarag Fredheim, Hans-Matti Blencke et al.:
    Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications
    International Journal of Molecular Sciences 2022 ARKIV / DOI
  • Marianne Hagensen Paulsen, Magnus Engqvist, Dominik Ausbacher, Trude Anderssen, Manuel K- Langer, Tor Haug et al.:
    Amphipathic Barbiturates as Mimics of Antimicrobial Peptides and the Marine Natural Products Eusynstyelamides with Activity against Multi-resistant Clinical Isolates
    Journal of Medicinal Chemistry 2021 ARKIV / DOI
  • Marianne Hagensen Paulsen, Dominik Ausbacher, Annette Bayer, Magnus Engqvist, Terkel Hansen, Tor Haug et al.:
    Antimicrobial activity of amphipathic α,α-disubstituted β-amino amide derivatives against ESBL–CARBA producing multi-resistant bacteria; effect of halogenation, lipophilicity and cationic character
    European Journal of Medicinal Chemistry 2019 ARKIV / DOI
  • Marianne Hagensen Paulsen, Eskil Andre Karlsen, Dominik Ausbacher, Trude Anderssen, Annette Bayer, Philipp Ochtrop et al.:
    An amphipathic cyclic tetrapeptide scaffold containing halogenated β2,2-amino acids with activity against multi-resistant bacteria
    Journal of Peptide Science 2018 DOI
  • Annfrid Sivertsen, Veronika Tørfoss, Johan Isaksson, Dominik Ausbacher, Trude Anderssen, Bjørn Olav Brandsdal et al.:
    Anticancer potency of small linear and cyclic tetrapeptides and pharmacokinetic investigations of peptide binding to human serum albumin
    Journal of Peptide Science 2014 DOI
  • Terkel Hansen, Morten Kaare Moe, Trude Anderssen, Morten B. Strøm :
    Metabolism of small antimicrobial β2,2-amino acid derivatives by murine liver microsomes
    European journal of drug metabolism and pharmacokinetics 2012 DOI
  • Terkel Hansen, Dominik Ausbacher, Zack Georg Zachariassen, Trude Anderssen, Martina Havelkova, Morten B. Strøm :
    Anticancer activity of small amphipathic β2,2-amino acid derivatives
    European Journal of Medicinal Chemistry 2012 DOI
  • Veronika Tørfoss, Johan Isaksson, Dominik Ausbacher, Bjørn Olav Brandsdal, Gøril Eide Flaten, Trude Anderssen et al.:
    Improved anticancer potency by head-to-tail cyclization of short cationic anticancer peptides containing a lipophilic b2,2-amino acid
    Journal of Peptide Science 2012 DOI
  • Terje Vasskog, Ove Bergersen, Trude Andersen, Einar Jensen, Trine Eggen :
    Depletion of selective serotonin reuptake inhibitors during sewage sludge composting
    Waste Management 2009 DOI
  • Terje Vasskog, T Anderssen, Trude Anderssen, Stig Pedersen-Bjergaard, Roland Kallenborn, Einar Jensen :
    Occurrence of selective serotonin reuptake inhibitors in sewage and receiving waters at Spitsbergen and in Norway
    Journal of Chromatography A 2008 DOI
  • Tung Si Ho, Si Tung Ho, Terje Vasskog, Trude Anderssen, Trude Anderssen, einar Jensen et al.:
    25,000-fold pre-concentration in a single step with liquid-phase microextraction
    Analytica Chimica Acta 2007 DOI
  • Morten Kaare Moe, Trude Anderssen, Morten B. Strøm, Einar Jensen :
    Total structure characterization of unsaturated acidic phospholipids provided by vicinal di-hydroxylation of fatty acid double bonds and negative electrospray ionization mass spectrometry
    Journal of the American Society for Mass Spectrometry 2005 DATA / DOI
  • Manuel K Langer, Ataur Rahman, Hymonti Dey, Trude Anderssen, Hans-Matti Blencke, Tor Haug et al.:
    Tetrasubstituted hydantoins: Novel membranolytic antimicrobials
    2023
  • Danijela Simonovic, Hymonti Dey, Natascha Johansen, Trude Anderssen, Terje Vasskog, Elizabeth G. Aarag Fredheim et al.:
    Investigation of the antimicrobial activity and proteolytic stability of the short analogues of the marine peptide EeCentrocin 1
    2022
  • Danijela Simonovic, Hymonti Dey, Natascha Johansen, Trude Anderssen, Terje Vasskog, Elizabeth G. Aarag Fredheim et al.:
    Investigation of the antimicrobial activity and proteolytic stability of the short analogues of the marine peptide EeCentrocin 1
    2021
  • Terje Vasskog, Trude Anderssen, Tung Si Ho, einar Jensen, Knut Einar Rasmussen, Stig Pedersen-Bjergaard :
    Liquid-Phase Micro Extraction of Basic Drugs from Environmental Samples
    2007
  • Terje Vasskog, Trude Anderssen, Tung Si Ho, Stig Pedersen-Bjergaard, einar Jensen :
    Liquid Phase Micro Extraction of Antidepressants from Large Sample Volumes; an Application for Waste-Water Analysis
    2007
  • Trude Anderssen, Janne erikke Mjelle, einar Jensen :
    Liquid Chromatography/Electrospray Ionization Mass Spectrometric Analysis of AQC Derivatives of Amino Acids
    2006

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    Research interests

    JOB DESCRIPTION

    Trude Anderssen is affiliated with the Natural Products and Medicinal Chemistry Research Group and teaches at various chemistry-related laboratory courses for pharmacy students. She provides in-house training in HSE for new students/employees at the research group.

    RESEARCH INTERESTS

    She assists on various research projects, including toxicity testing of synthesis products.

    TEACHING

    Teaches laboratory courses in the following subjects:

    FAR-1302 Pharmaceutical Organic Chemistry
    FAR-2301 Medicinal chemistry and natural products chemistry
    FAR-2302 Pharmaceutical analysis

    Teaching

    Teaches laboratory courses in the following subjects:

    FAR-1302 Pharmaceutical Organic Chemistry
    FAR-2301 Medicinal chemistry and natural products chemistry
    FAR-2302 Pharmaceutical analysis

    Internal HSE training at the research group