Bilde av Andersen, Sigve
Bilde av Andersen, Sigve
Department of Clinical Medicine sigve.andersen@uit.no 99483689 You can find me here

Sigve Andersen


Professor in Oncology and Palliative Medicine

Job description

I mostly do translational research in NSCLC, butr I am also involved in research in other cancer types like prostate and colorectal cancer. I mainly teach palliative medicine, but also general cancer care. At the university I am also a member of the exam commitee for the final exams at medical school.


  • Marianne Jensen Hjermstad, Aleksandra Pirnat, Nina Kathrine Aass, Sigve Andersen, Guro Lindviksmoen Astrup, Olav Dajani et al.:
    PALLiative care in ONcology (PALLiON): A cluster-randomised trial investigating the effect of palliative care on the use of anticancer treatment at the end of life
    Palliative Medicine 09. January 2024 ARKIV / FULLTEKST / DOI
  • Line Veronika Hjelle, Marie Grøn Sælen, Erling Johan Aarsæther, Tore Knutsen, Sigve Andersen, Anne Gry Bentzen et al.:
    The Longitudinal Course of Prospectively Recorded Patient-reported Outcomes in Prostate Cancer Patients Treated with Surgery and Salvage Radiotherapy
    European Urology Open Science 2023 ARKIV / DOI
  • Erna-Elise Paulsen, Sigve Andersen, Mehrdad Rakaee, Mona Irene Pedersen, Ana Paola Lombardi, Mette Pøhl et al.:
    Impact of microvessel patterns and immune status in NSCLC: a non-angiogenic vasculature is an independent negative prognostic factor in lung adenocarcinoma
    Frontiers in Oncology 2023 ARKIV / DOI
  • Mehrdad Rakaee, Sigve Andersen, K. Giannikou, Erna-Elise Paulsen, Thomas Karsten Kilvær, Lill-Tove Rasmussen Busund et al.:
    Machine learning-based immune phenotypes correlate with STK11/KEAP1 co-mutations and prognosis in resectable NSCLC: a sub-study of the TNM-I trial
    Annals of Oncology 2023 ARKIV / DOI
  • Hallgeir Selven, Lill-Tove Rasmussen Busund, Sigve Andersen, Mona Irene Pedersen, Ana Paola Lombardi, Thomas Karsten Kilvær :
    High Expression of IRS-1, RUNX3 and SMAD4 Are Positive Prognostic Factors in Stage I–III Colon Cancer
    Cancers 2023 ARKIV / DOI
  • Marie Grøn Sælen, Line Veronika Hjelle, Erling Johan Aarsæther, Tore Knutsen, Sigve Andersen, Anne Gry Bentzen et al.:
    Patient-reported outcomes after curative treatment for prostate cancer with prostatectomy, primary radiotherapy or salvage radiotherapy
    Acta Oncologica 2023 ARKIV / DOI
  • Therese Haugdahl Nøst, Anne Heidi Skogholt, Ilona Halva Urbarova, Robin Mjelle, Erna-Elise Paulsen, Tom Dønnem et al.:
    Increased levels of microRNA-320 in blood serum and plasma is associated with imminent and advanced lung cancer
    Molecular Oncology 2022 ARKIV / DOI
  • Mehrdad Rakaee, Elio Adib, Biagio Ricciuti, Lynette M. Sholl Sholl, Weiwei Shi, Joao V. Alessi et al.:
    Association of machine learning-based assessment of tumor-infiltrating lymphocytes on standard histologic images with outcomes of immunotherapy in patients with NSCLC
    JAMA Oncology 17. November 2022 DOI
  • Hallgeir Selven, Sigve Andersen, Mona Irene Pedersen, Ana Paola Lombardi, Lill-Tove Rasmussen Busund, Thomas Karsten Kilvær :
    High expression of miR-17-5p and miR-20a-5p predicts favorable disease-specific survival in stage I-III colon cancer
    Scientific Reports 2022 ARKIV / DOI
  • Sissel Gyrid Freim Wahl, Yan Dai Hong, Elisabeth Fritzke Emdal, Thomas Berg, Tarje Onsøien Halvorsen, Anine Larsen Ottestad et al.:
    The prognostic effect of KRAS mutations in non-small cell lung carcinoma revisited: A norwegian multicentre study
    Cancers 2021 ARKIV / DOI
  • Håkon Andre Ramberg, Elin Richardsen, Gustavo Antonio De Souza, Mehrdad Rakaee, Maria Stensland, Peder Rustøen Braadland et al.:
    Proteomic analyses identify major vault protein as a prognostic biomarker for fatal prostate cancer
    Carcinogenesis 2021 ARKIV / DOI
  • Mehrdad Rakaee, Thomas Karsten Kilvær, Simin Jamaly, Thomas Berg, Erna-Elise Paulsen, Marte Berglund et al.:
    Tertiary lymphoid structure score: a promising approach to refine the TNM staging in resected non-small cell lung cancer
    British Journal of Cancer 2021 DOI
  • Maria Jenvin Støen, Sigve Andersen, Mehrdad Rakaee, Mona Irene Pedersen, Lise Martine Ingebriktsen, Roy M. Bremnes et al.:
    High expression of miR-17-5p in tumor epithelium is a predictor for poor prognosis for prostate cancer patients
    Scientific Reports 2021 ARKIV / DOI
  • Hallgeir Selven, Lill-Tove Rasmussen Busund, Sigve Andersen, Roy M. Bremnes, Thomas Karsten Kilvær :
    High expression of microRNA‑126 relates to favorable prognosis for colon cancer patients
    Scientific Reports 2021 ARKIV / DOI
  • Maria Jenvin Støen, Sigve Andersen, Mehrdad Rakaee, Mona I. Pedersen, Lise Martine Ingebriktsen, Tom Dønnem et al.:
    Overexpression of mir-20a-5p in tumor epithelium is an independent negative prognostic indicator in prostate cancer—a multi-institutional study
    Cancers 2021 ARKIV / DOI
  • Thomas Karsten Kilvær, Erna-Elise Paulsen, Sigve Andersen, Mehrdad Rakaee, Roy M. Bremnes, Lill-Tove Rasmussen Busund et al.:
    Digitally quantified CD8+ cells: the best candidate marker for an immune cell score in non-small cell lung cancer?
    Carcinogenesis 2020 ARKIV / DOI
  • Mehrdad Rakaee, Lill-Tove Busund, Simin Jamaly, Erna-Elise Paulsen, Elin Richardsen, Sigve Andersen et al.:
    Prognostic Value of Macrophage Phenotypes in Resectable Non–Small Cell Lung Cancer Assessed by Multiplex Immunohistochemistry
    Neoplasia 12. February 2019 ARKIV / DOI
  • Elin Richardsen, Sigve Andersen, Christian Melbø-Jørgensen, Mehrdad Rakaee, Nora Ness, Samer Al-Saad et al.:
    MicroRNA 141 is associated to outcome and aggressive tumor characteristics in prostate cancer
    Scientific Reports 2019 ARKIV / DOI
  • Elin Richardsen, Sigve Andersen, Samer Al-Saad, Mehrdad Rakaee, Yngve Nordby, Mona Irene Pedersen et al.:
    Low expression of miR-424-3p is highly correlated with clinical failure in prostate cancer
    Scientific Reports 2019 ARKIV / DOI
  • Sigurd Hald, Mehrdad Rakaee, Inigo Zubiavrre Martinez, Elin Richardsen, Samer Al-Saad, Erna Elise Paulsen et al.:
    LAG-3 in Non-Small-cell Lung Cancer: Expression in Primary Tumors and Metastatic Lymph Nodes Is Associated With Improved Survival
    Clinical Lung Cancer 2018 DOI
  • Yury Kiselev, Sigve Andersen, Charles Johannessen, Bjørn Fjukstad, Karina Standahl Olsen, Helge Stenvold et al.:
    Transcription factor PAX6 as a novel prognostic factor and putative tumour suppressor in non-small cell lung cancer
    Scientific Reports 2018 ARKIV / DOI
  • Kaja Konstanse Skjefstad, Charles Johannessen, Thea K.W. Grindstad, Thomas Karsten Kilvær, Erna Elise Paulsen, Mona Irene Pedersen et al.:
    A gender specific improved survival related to stromal miR-143 and miR-145 expression in non-small cell lung cancer
    Scientific Reports 2018 ARKIV / DOI
  • Mehrdad Rakaee, Thomas Karsten Kilvær, Stig Manfred Dalen, Elin Richardsen, Erna Elise Paulsen, Sigurd Hald et al.:
    Evaluation of tumor-infiltrating lymphocytes using routine H&E slides predicts patient survival in resected non-small cell lung cancer
    Human Pathology 2018 DOI
  • Thea K.W. Grindstad, Elin Richardsen, Sigve Andersen, Kaja Konstanse Skjefstad, Mehrdad Rakaee, Tom Dønnem et al.:
    Progesterone receptors in prostate cancer: Progesterone receptor B is the isoform associated with disease progression
    Scientific Reports 2018 ARKIV / DOI
  • Nora Ness, Sigve Andersen, Mehrdad Rakaee, Cecilie Nordbakken, Andrey Yurjevich Valkov, Erna-Elise Paulsen et al.:
    The prognostic role of immune checkpoint markers programmed cell death protein 1 (PD-1) and programmed death ligand 1 (PD-L1) in a large, multicenter prostate cancer cohort
    OncoTarget 2017 ARKIV / DOI
  • Elin Richardsen, Sigve Andersen, Samer Al-Saad, Mehrdad Rakaee, Yngve Nordby, Mona Irene Pedersen et al.:
    Evaluation of the proliferation marker Ki-67 in a large prostatectomy cohort
    PLOS ONE 2017 ARKIV / DOI
  • Yngve Nordby, Elin Richardsen, Nora Ness, Tom Dønnem, Hitendra R.H. Patel, Lill-Tove Busund et al.:
    High miR-205 expression in normal epithelium is associated with biochemical failure - An argument for epithelial crosstalk in prostate cancer?
    Scientific Reports 2017 ARKIV / DOI
  • Erna-Elise Paulsen, Thomas Karsten Kilvær, Mehrdad Rakaee, Elin Richardsen, Sigurd Hald, Sigve Andersen et al.:
    CTLA-4 expression in the non-small cell lung cancer patient tumor microenvironment: diverging prognostic impact in primary tumors and lymph node metastases
    Cancer Immunology and Immunotherapy 2017 ARKIV / DOI
  • falah jabar, Sigve Andersen, Erna-Elise Paulsen, Masoud Tafavvoghi, Elin Helmine Richardsen, Sissel Gyrid Freim Wahl et al.:
    Integrating Artificial intelligence (AI)-based lymphocytic infiltration assessment in early-stage NSCLC: A sub-study of the TNM-I trial
    2024
  • Tonje Lundeby, Nina Kathrine Aass, Sigve Andersen, Sjur Bjørnar Hanssen, Marianne Jensen Hjermstad, Stein Kaasa et al.:
    Family carers' experiences with brain metastases: A longitudinal study
    2023
  • Øyvind Rolland, Sigve Andersen, Stian Aagnes, Åslaug Helland :
    Stian har livstruende lungekreft: – Jeg er beviset på at forskning nytter
    08. June 2023
  • Marianne Jensen Hjermstad, Aleksandra Pirnat, Nina Kathrine Aass, Sigve Andersen, Guro Lindviksmoen Astrup, Olav Dajani et al.:
    1592MO Anticancer therapy at the end-of-life: A cluster-randomized trial
    Annals of Oncology 2023 DOI
  • Mehrdad Rakaee, Elio Adib, Biagio Ricciuti, Lynette M. Sholl, Joao V.Alessi, Alessio Cortellini et al.:
    Digital quantification of lymphocytic infiltration on routine H&E images and immunotherapy response in non-small cell lung cancer
    2022
  • Mehrdad Rakaee, Elio Adib, Biagio Ricciuti, Lynette M. Sholl, Weiwei Shi, Joao V.Alessi et al.:
    Artificial intelligence in digital pathology approach identifies the predictive impact of tertiary lymphoid structures with immune-checkpoints therapy in NSCLC
    2022
  • Therese Haugdahl Nøst, Ilona Halva Urbarova, Anne Heidi Skogholt, Robin Mjelle, Erna Elise Paulsen, Tom Dønnem et al.:
    Increased levels of mRNAs and miRNAs associated with imminent and advanced lung cancer
    2022
  • Mehrdad Rakaee, Elio Adib, Biagio Ricciuti, Lynette M. Sholl, Weiwei Shi, Joao V Alessi et al.:
    Computational pathology by Artificial Intelligence (AI) on quantifying the lymphocytic infiltration predicts the immunotherapy response in NSCLC
    2022
  • Marianne Jensen Hjermstad, Nina Kathrine Aass, Sigve Andersen, Cinzia Brunelli, Olav Dajani, Herish Ahmed et al.:
    PALLiON - PALLiative care Integrated in ONcology: Study protocol for a Norwegian national cluster-randomized control trial with a complex intervention of early integration of palliative care
    Trials 2020 FULLTEKST / ARKIV / DOI
  • Bente Ervik, Sigve Andersen, Helge Skirbekk, Tom Dønnem :
    Evaluating a centralised cancer support centre in the remote region of Northern Norway
    Rural and remote health 02. September 2020 ARKIV / DOI
  • Marianne Bahus, Sigve Andersen, Peder Broen, Helge Farsund, Anne Marie Flovik, Søren Vincent Hagerup et al.:
    Organisering av det palliative tilbudet Faglig begrunnet eller et udemokratisk politisk spill?
    Fædrelandsvennen 24. August 2020
  • Stein Kaasa, Marianne Bahus, Sigve Andersen, Peder Broen, Helge Farsund, Anne Marie Flovik et al.:
    De er døende. Gi dem lindring
    Dagbladet 2020
  • Sigve Andersen, Tom Dønnem :
    Krafttak mot kreft
    14. March 2019
  • Bente Ervik, Tone Nordøy, Sigve Andersen :
    Fruktene av "Lindring i nord"
    Omsorg: Nordisk tidsskrift for Palliativ Medisin 01. April 2019 ARKIV / FULLTEKST
  • Tom Dønnem, Sigve Andersen :
    Jakter på kroppens krigerceller
    05. September 2019
  • Jan Henrik Rosland, Olav Hevrøy, Birthe Lie Hauge, Anne Kari Knudsen, Peder Broen, Sigve Andersen :
    Nasjonalt handlingsprogram for palliasjon i kreftomsorgen
    2019
  • Tom Dønnem, Sigve Andersen :
    Jakter på kroppens krigerceller
    18. September 2019
  • Sigve Andersen :
    Folkemøte om prostatakreft
    2019
  • Kristin Benjaminsen Borch, Sigve Andersen, Line Merethe Oldervoll, Sveinung Berntsen :
    Hva vet onkologer om fysisk aktivitet og kreft?
    2019
  • Kaja Konstanse Skjefstad, Thea K.W. Grindstad, Mehrdad Rakaee, Elin Richardsen, Tom Dønnem, Thomas Karsten Kilvær et al.:
    Corrigendum to "Prognostic relevance of estrogen receptor α, β and aromatase expression in non-small cell lung cancer" [Steroids 113 (2016) 5-13]
    Steroids 2018 DOI
  • Stein Kaasa, Sigve Andersen, Marianne Klungland Bahus, Peder Broen, Helge Farsund, Anne Marie Flovik et al.:
    NOU 2017:16 : På liv og død : Palliasjon til alvorlig syke og døende : utredning fra utvalg oppnevnt ved kongelig resolusjon 11. mai 2016. Avgitt til Helse- og omsorgsdepartementet 20. desember 2017
    2017 FULLTEKST
  • Sigve Andersen, Tom Dønnem, Bodil Trosten, Kari Margrethe Larsen, Tone Nordøy, Bente Ervik :
    Palliative indicators in a university hospital - a cross-sectional prevalence study combined with ESAS-r symptom assesment and follow up of death
    2017

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    Research interests

    Translational reserach in lung cancer and prostate cancer

    Palliative care