Job description

Keywords:

Nanolithography, Nanoscopy, Nanofluidics, 2PL, STED, Soft lithography, Single molecule diffusional sizing, Antibody binding, protein-ligand interactions, sm-FRET, DNA, Protein misfolding disease, Alzheimers, Parkinsons disease, NanoSpacer, Amyloid-on-chip  

Dr. Oliver Vanderpoorten is Principal Investigator (UiT Innovation grant) at UiT and part of the Photonics Group at the Department of Physics and Technology (IFT).

The Vanderpoorten lab is specialized in single molecule metrology and nano-dynamic imaging of molecular interactions in liquid solutions related to biotechnology and environmental sensing. Techniques used in the V-lab are: (i) label-free and fluorescence microscopy for imaging, (ii) UV-, and 2-photon lithography for nanofabrication and (iii) nanofluidics for confinement to analyze bacteria, nanoparticles, nanoplastics, exosomes, viruses, DNA, RNA and protein molecules in solution with/without conventional fluorescent labelling. The lab's current research focus are dynamics of DNA and RNA constructs as well as amyloid-forming species and oligomers related to Alzheimer’s and Parkinson disease and their study on a single molecule level - combining the tools of "Nanolithography - Nanoscopy -  Nanofluidics" to accelerate drug development against amyloid formation and improved screening for aggregation inhibitors. 

Additional interests/projects: Optical trapping, Active colloids, Nanofiltration, 3D microscopy, Organ-on-a-chip, Radiology, Fertility, DNA-origami, MOF, Nanobubbles, Nanodroplets