Bilde av Rinaldo, Christine Hanssen
Photo: Bjørn-Kåre Iversen
Bilde av Rinaldo, Christine Hanssen
Department of Clinical Medicine christine.rinaldo@uit.no Tromsø

Rinaldo, Christine Hanssen


Job description

Reseach, teaching and supervision in virology


  • Kirsten Midttun Gravningen, Stian Henriksen, Olav Hungnes, Kristian Svendsen, Emily Ann Macdonald, Henrik Schirmer et al.:
    Risk factors, immune response and whole‐genome sequencing of SARS‐CoV‐2 in a cruise ship outbreak in Norway
    International Journal of Infectious Diseases 2022 ARKIV / DOI
  • Christine Hanssen Rinaldo, Ingebjørg Helena Nymo, Javier Sanchez Romano, Eva Marie Breines, Francisco Javier Ancin Murguzur, Morten Tryland :
    Serological evidence of hepatitis e virus infection in semi-domesticated eurasian tundra reindeer (Rangifer tarandus tarandus) in norway
    Pathogens 2021 ARKIV / DOI
  • Stian Henriksen, Christine Hanssen Rinaldo :
    Does the Evidence Support the Existence of the Simian Polyomavirus SV40 Vp4 Viroporin?
    mSphere 2020 ARKIV / DOI
  • Julia Manzetti, Fabian H. Weissbach, Fabrice E. Graf, Gunhild Unterstab, Marion Wernli, Helmut Hopfer et al.:
    BK polyomavirus evades innate immune sensing by disrupting the mitochondrial network and promotes mitophagy
    iScience 10. June 2020 ARKIV / DOI
  • Irene Beate Olsøy, Stian Henriksen, Fabian H. Weissbach, Marthe Larsen, Karoline Borgen, Florence Abravanel et al.:
    Seroprevalence of hepatitis E virus (HEV) in a general adult population in Northern Norway: the Tromsø study
    Medical Microbiology and Immmunology 2019 ARKIV / DOI
  • Simone Cesaro, Tina Dalianis, Christine Hanssen Rinaldo, Minna Koskenvuo, Anna Pegoraro, Hermann Einsele et al.:
    ECIL guidelines for the prevention, diagnosis and treatment of BK polyomavirus-associated haemorrhagic cystitis in haematopoietic stem cell transplant recipients
    Journal of Antimicrobial Chemotherapy 2018 DOI
  • Karl Bjørnar Alstadhaug, Kjell-Morten Myhr, Christine Hanssen Rinaldo :
    Progredierende multifokal leukoencefalopati
    Tidsskrift for Den norske legeforening 12. December 2017 DOI
  • Stian Henriksen, Christian Mittelholzer, Rainer Gosert, Hans H Hirsch, Christine Hanssen Rinaldo :
    Human BK polyomavirus plasmid pBKV (34-2) (Dunlop) contains mutations not found in the originally published sequences
    Microbiology Resource Announcements (MRA) 2016 DOI
  • Stian Henriksen, Terkel Hansen, Jack-Ansgar Bruun, Christine Hanssen Rinaldo :
    The Presumed Polyomavirus Viroporin VP4 of Simian Virus 40 or Human BK Polyomavirus Is Not Required for Viral Progeny Release
    Journal of Virology 2016 ARKIV / DOI
  • John C. Papadimitriou, Parmjeet Singh Randhawa, Christine Hanssen Rinaldo, Cinithia B. Drachenberg, Borislav A. Alexiev, H. H. Hirsch :
    BK polyomavirus infection and renourinary tumorigenesis
    American Journal of Transplantation 2016 DOI
  • Garth Daryl Tylden, Hans H. Hirsch, Christine Hanssen Rinaldo :
    Brincidofovir (CMX001) inhibits BK polyomavirus replication in primary human urothelial cells
    Antimicrobial Agents and Chemotherapy 2015 DOI
  • Jaione Simon-Santamaria, Christine Hanssen Rinaldo, Piotr Kardas, Ruomei Li, Ivana Malovic, kjetil helge Elvevold et al.:
    Efficient uptake of blood-borne BK and JC polyomavirus-like particles in endothelial cells of liver sinusoids and renal vasa recta
    PLOS ONE 2014 ARKIV / DOI
  • Stian Henriksen, Garth Daryl Tylden, Alexis Dumoulin, Sharma Biswa Nath, Hans H. Hirsch, Christine Hanssen Rinaldo :
    The human fetal glial cell line SVG p12 contains infectious BK polyomavirus
    Journal of Virology 2014 DOI
  • Biswa Nath Sharma, Manfred Marschall, Stian Henriksen, Christine H Rinaldo :
    Antiviral effects of artesunate on polyomavirus BK replication in primary human kidney cells
    Antimicrobial Agents and Chemotherapy 2014 DOI
  • HH Hirsch, N Babel, P Comoli, V Friman, F Ginevri, AG Jardine et al.:
    European perspective on human polyomavirus infection, replication and disease in solid organ transplantation.
    Clinical Microbiology and Infection (CMI) 2014 DOI
  • Biswa Nath Sharma, Manfred Marschall, Christine Hanssen Rinaldo :
    Antiviral effects of artesunate on JC polyomavirus replication in COS-7 Cells
    Antimicrobial Agents and Chemotherapy 2014 DOI
  • Karl Bjørnar Alstadhaug, Thérèse Croughs, Stian Henriksen, Céline Leboeuf, Irini Sereti, Hans H. Hirsch et al.:
    Treatment of progressive multifocal leukoencephalopathy with interleukin 7
    JAMA Neurology 2014 DOI
  • Christine H Rinaldo, Garth Daryl Tylden, Biswa Nath Sharma :
    The human polyomavirus BK (BKPyV): virological background and clinical implications
    APMIS - Journal of Pathologiy, Microbiology and Immunology 2013 DOI
  • Ruomei Li, Biswa Nath Sharma, Stig Linder, Tore Jarl Gutteberg, Hans H. Hirsch, Christine H Rinaldo :
    Characteristics of polyomavirus BK (BKPyV) infection in primary human urothelial cells
    Virology 2013 DOI
  • Rainer Gosert, Christine H Rinaldo, Marion Wernli, Eugene O. Major, Hans H. Hirsch :
    CMX001 (1-O-Hexadecyloxypropyl-Cidofovir) Inhibits Polyomavirus JC Replication in Human Brain Progenitor-Derived Astrocytes
    Antimicrobial Agents and Chemotherapy 2011 DOI
  • Christiane Beckmann, Alexis Dumoulin, Christine H Rinaldo, Hans H. Hirsch :
    Comparison of a UL111a Real-time PCR and pp65 Antigenemia for the Detection of Cytomegalovirus
    Journal of Medical Virology 2011 DOI
  • Biswa Nath Sharma, Ruomei Li, Eva Bernhoff, Tore Jarl Gutteberg, Christine H Rinaldo :
    Fluoroquinolones inhibit human polyomavirus BK (BKV) replication in primary human kidney cells
    Antiviral Research 2011 DOI
  • Anett Kristin Larsen, Javier Sanchez Romano, Jaione Simon-Santamaria, Kim Erlend Mortensen, Bo Gøran Ericzon, Peter Anthony McCourt et al.:
    Role of liver sinusoidal endothelial cells in elimination of virus
    2022
  • Anett Kristin Larsen, Javier Sanchez Romano, Eirik Abrahamsen Lænsman, Anne Lotte Vada Hatlegjerde, Jaione Simon-Santamaria, Kim Erlend Mortensen et al.:
    Liver sinusoidal scavenger cells eliminate betaherpesvirus from the blood stream
    2022
  • Christine Hanssen Rinaldo :
    Tysk professor mener tap av smakssans kan være koronategn: - Ikke utenkelig, sier UNN-forsker
    17. March 2020
  • Christine Hanssen Rinaldo :
    SARS-CoV-2 pandemi
    13. March 2020
  • Christine Hanssen Rinaldo :
    SARS-CoV-2 mutasjoner
    24. October 2020
  • Christine Hanssen Rinaldo :
    Coronasyke i Norge: Slik er det å være smittet.
    19. March 2020
  • Christine Hanssen Rinaldo :
    Her smittes friske i jakten på vaksine
    21. March 2020
  • Christine Hanssen Rinaldo :
    4 scenarioer: Slik slutter pandemien.
    14. April 2020
  • Stian Henriksen, Øyvind Trydal, Sten-Eigil Sigurdsen, Garth Daryl Tylden, Christine Hanssen Rinaldo :
    Antistoffrespons hos en familie med covid-19
    Tidsskrift for Den norske legeforening 2020 DOI
  • Christine Hanssen Rinaldo :
    24 spørsmål og svar: Dette vet ekspertene om coronavaksine.
    25. March 2020
  • Christine Hanssen Rinaldo :
    SARS-CoV-2
    27. March 2020
  • Christine Hanssen Rinaldo :
    Kan det komme en ny bølge med coronavirus? Forskerne svarer.
    26. March 2020
  • Karl Bjørnar Alstadhaug, Christine Hanssen Rinaldo, Liv T. N. Osnes, Irini Sereti, Hilde Karen Ofte :
    Progressive multifocal leukoencephalopathy treated with interleukin-7
    Clinical Infection in Practice 2020 DOI
  • Elias Myrvoll Lorentzen, Stian Henriksen, Amandeep Kaur, Grete Anette Birkeland Kro, Clara Louise Hammarström, Hans H Hirsch et al.:
    Early fulminant BK polyomavirus-associated nephropathy in two kidney transplant patients with low neutralizing antibody titers receiving allografts from the same donor
    Virology Journal 2020 ARKIV / DOI
  • Irene Beate Olsøy, Stian Henriksen, Fabian H. Weissbach, Marthe Larsen, Katrine Borgen, Florence Abravanel et al.:
    Correction to: Seroprevalence of hepatitis E virus (HEV) in a general adult population in Northern Norway: the Tromsø study (Medical Microbiology and Immunology, (2019), 208, 6, (715-725), 10.1007/s00430-019-00599-5)
    Medical Microbiology and Immmunology 2019 DOI
  • Christine Hanssen Rinaldo, Garth Daryl Tylden :
    Medisinsk mikrobiologi, Kapittel 28, Papillomavirus og polyomavirus
    Gyldendal Akademisk 2019
  • Javier Sanchez Romano, Anett Kristin Larsen, kjetil helge Elvevold, Christopher Florian Holte, Jaione Simon-Santamaria, Hans H. Hirsch et al.:
    SECVIR - The role of scavenger endothelial cells in elimination of virus
    2019
  • Jaione Simon-Santamaria, Christine H Rinaldo, Piotr Kardas, Ruomei Li, Ivana Malovic, Kjetil H. Elvevold et al.:
    Role of scavenger endothelial cells in polyomavirus JC and BK clearance
    2014
  • Christine Hanssen Rinaldo, Stian Henriksen, Garth Daryl Tylden, Hans H. Hirsch :
    Reply to "contamination of SVG p12 cells with BK polyomavirus occurred after deposit in the American type culture collection"
    Journal of Virology 2014 DOI
  • Karl Bjørnar Alstadhaug, Therese Croughs, Stian Henriksen, Irini Sereti, Hans H. Hirsch, Christine Hanssen Rinaldo :
    A patient with idiopathic CD4+ T-cell lymphocytopenia and progressiv mulitifocal leukoencephalopathy: treatment by recombinant interleukin-7 and characterization of polyomavirus JC
    2014
  • Christine H Rinaldo, Hans H. Hirsch :
    The human polyomaviruses: from orphans and mutants to patchwork family
    APMIS - Journal of Pathologiy, Microbiology and Immunology 2013 DOI
  • Christine H Rinaldo, Biswa Nath Sharma, Marschall Manfred, Stian Henriksen, Tore Jarl Gutteberg :
    Effects of Artesunate on Polyomavirus BK Replication in Primary Human Renal Tubular Epithelial Cells
    2013
  • Biswa Nath Sharma, Manfred Marschall, Stian Henriksen, Tore Jarl Gutteberg, Christine H Rinaldo :
    Antiviral effects of artesunate on polyomavirus BK replication in primary human renal tubular epithelial cells
    Journal of Neurovirology 2013
  • Hans H. Hirsch, Christiane Beckmann, Alexis Dumoulin, Enid Dørmenen, Christine Bauer, Christine Hanssen Rinaldo :
    Cytomegalovirus and Epstein-Barr Virus PCR quantification: impact of sample matrix and extraction methods in a two-centers comparative study and implementation of the first WHO International Standard for Cytomegalovirus
    2012
  • Biswa Nath Sharma, Manfred Marschall, Stian Henriksen, Tore Jarl Gutteberg, Christine Hanssen Rinaldo :
    Antiviral Effects of Artesunate on Polyomavirus BK Replication in Primary Human Kidney Cells
    2012
  • Christine Hanssen Rinaldo, Ruomei Li, Biswa Nath Sharma, Stig Linder, Tore Jarl Gutteberg, Hans H. Hirsch :
    Polyomavirus BK (BKV) replication in human urothelial cells - role in polyomavirus associated hemorrhagic cystitis and nephropathy
    2012
  • Christine H Rinaldo, Ruomei Li, Biswa Nath Sharma, Stig Linder, Tore Jarl Gutteberg, Hans H. Hirsch :
    Polyomavirus BK (BKV) Replication in Human Urothelial Cells Role in Polyomavirus-Associated Nephropathy and Hemorrhagic Cystitis
    American Journal of Transplantation 2012
  • Jaione Simon-Santamaria, Ruomei Li, Piotr Kardas, Ivana Malovic, Kjetil H. Elvevold, Peter Anthony McCourt et al.:
    Role of liver sinusoidal endothelial cells in blood clearance of polyomavirus BK and JC
    2012

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    Research interests

    Human polyomavirus (HPyV): BKPyV and JCPyV

    Hepatitis E-virus (HEV)

    Cytomegalovirus (CMV)

    Herpes simples virus 1 (HSV-1)

    SARS-CoV-2

    Virus replication; virus-cell interactions; pathogenesis; immunity; cancer; antiviral treatment; diagnostics