Drug discovery

Protein kinases are a major class of drug targets

https://pubs.acs.org/cms/10.1021/acs.biochem.1c00359/asset/images/large/bi1c00359_0010.jpeg

From: Drugging the Undruggable: How Isoquinolines and PKA Initiated the Era of Designed Protein Kinase Inhibitor Therapeutics, Robin Lorenz, Jian Wu, Friedrich W. Herberg, Susan S. Taylor, and Richard A. Engh
Biochemistry 202160 (46), 3470-3484
DOI: 10.1021/acs.biochem.1c00359