Bilde av Ravna, Aina Westrheim
Bilde av Ravna, Aina Westrheim
Researcher Eksperimentell og klinisk farmakologi aina.w.ravna@uit.no +4777644706 You can find me here

Aina Westrheim Ravna


Job description

Research on drug targets using molecular modeling techniques.

Teaches pharmacology for medical students, odontology students, nurse students and biology students.

Communicates own research and popular scienctific topics such as chocolate, spices and traditional sami medicine (shamanism).


  • Adrina Kalasho, Anders Lund Selli, Natalia Smaglyukova, Timofey Kondratyev, Ole Martin Fuskevåg, Roy Andre Lyså et al.:
    Treatment of Cardiovascular Dysfunction with PDE3-Inhibitors in Moderate and Severe Hypothermia—Effects on Cellular Elimination of Cyclic Adenosine Monophosphate and Cyclic Guanosine Monophosphate
    Frontiers in Physiology 2022 ARKIV / DOI
  • Ingmar Trane, Georg Sager, Erik Sveberg Dietrichs, Aina Westrheim Ravna :
    Molecular modeling study of the testosterone metabolizing enzyme UDP-glucuronosyltransferase 2B17
    Bioorganic & Medicinal Chemistry 2021 ARKIV / DOI
  • Anders Lund Selli, Adrina Kalasho Kuzmiszyn, Natalia Smaglyukova, Timofey Kondratyev, Ole Martin Fuskevåg, Roy Andre Lyså et al.:
    Treatment of cardiovascular dysfunction with PDE5-inhibitors - temperature dependent effects on transport and metabolism of cAMP and cGMP
    Frontiers in Physiology 2021 ARKIV / DOI
  • Sondre Ulstein Odland, Aina Westrheim Ravna, Natalia Smaglyukova, Erik Sveberg Dietrichs, Georg Sager :
    Inhibition of ABCC5-mediated cGMP transport by progesterone, testosterone and their analogues
    Journal of Steroid Biochemistry and Molecular Biology 2021 ARKIV / DOI
  • Farzane Kuresh Kashgari, Aina Westrheim Ravna, Georg Sager, Roy Andre Lyså, Istvan Enyedy, Erik Sveberg Dietrichs :
    Identification and experimental confirmation of novel cGMP efflux inhibitors by virtual ligand screening of vardenafil-analogues
    Biomedicine & Pharmacotherapy 2020 ARKIV / DOI
  • Gloria Antobreh, Istvan Enyedy, Aina Westrheim Ravna :
    Molecular modeling and docking studies of the oxytocin receptor
    Future Medicinal Chemistry 2018 DOI
  • Anna Subbotina, Aina Westrheim Ravna, Roy Andre Lyså, Ruben Abagyan, Ryszard Bugno, Georg Sager :
    Inhibition of PDE5A1 guanosine cyclic monophosphate (cGMP) hydrolysing activity by sildenafil analogues that inhibit cellular cGMP efflux
    Journal of Pharmacy and Pharmacology (JPP) 2017 ARKIV / DOI
  • Aina Westrheim Ravna :
    Hvor mange vi selger i løpet av ett år? Å hælsikke...
    04. October 2024
  • Aina Westrheim Ravna :
    Dropper smarttelefon: – Ingen grunn til å gå tilbake
    30. June 2024
  • Aina Westrheim Ravna :
    Samisk sjamanisme og samisk medisinsk tilnærming
    2024
  • Aina Westrheim Ravna :
    Podcastintervju om mobilavhengighet
    29. February 2024
  • Aina Westrheim Ravna :
    Derfor blir du hekta
    NRK.no 2024
  • Aina Westrheim Ravna :
    Hvorfor er vi blitt så avhengige av mobilen
    iFinnmark 2024
  • Aina Westrheim Ravna :
    Samisk dynamitt
    Nordnorsk Debatt 2023
  • Aina Westrheim Ravna :
    Svar til Hellesvik angående samiske genstudier
    Nordnorsk Debatt 2023
  • Aina Westrheim Ravna :
    Vår smarte kropp gir lykkerus
    10. March 2023
  • Aina Westrheim Ravna :
    Stadig fleire KI-romansar: – Kjærleik ­fri for risiko
    NRK.no 2023
  • Aina Westrheim Ravna :
    Manglende kildehenvisninger
    Dag og Tid 2023
  • Aina Westrheim Ravna :
    Surr om «ursamisk nærvær»
    Aftenposten (morgenutg. : trykt utg.) 2023
  • Aina Westrheim Ravna :
    Vennskap og vitenskap
    Dag og Tid 2023
  • Aina Westrheim Ravna :
    Samene stammer fra Afrika
    Aftenposten (morgenutg. : trykt utg.) 27. March 2023
  • Aina Westrheim Ravna :
    Samisk genforskning
    Dag og Tid 2023
  • Aina Westrheim Ravna :
    Hvilke data kan Benedictow vise til?
    Aftenposten (morgenutg. : trykt utg.) 2023
  • Aina Westrheim Ravna :
    Samenes formødre representerer en eldgammel, genetisk isolert befolkning fra Fennoskandia
    Nordnorsk Debatt 20. March 2023 FULLTEKST
  • Aina Westrheim Ravna :
    Gir økt sexlyst
    nationen.no 2023
  • Aina Westrheim Ravna :
    Forskning: Dette gjør sukker med helsen din
    VG : Verdens gang 2023
  • Aina Westrheim Ravna :
    Julekrydderet som kan gjøre oss gladere (Eller: Hvorfor ha kanel i kakaoen)
    20. November 2023
  • Aina Westrheim Ravna, Bror Reinhardt Olsen :
    Vestlige gener og østlig språk: Paradokset i samenes historie (https://www.sagat.no/vestlige-gener-og-ostlig-sprak-paradokset-i-samenes-historie/19.30970)
    Ságat 2022
  • Farzane Kuresh Kashgari, Aina Westrheim Ravna, Georg Sager, Roy Andre Lyså, Istvan Enyedy, Erik Sveberg Dietrichs :
    Corrigendum to “Identification and experimental confirmation of novel cGMP efflux inhibitors by virtual ligand screening of vardenafil-analogues” [Biomed. Pharmacother. 126 (2020) 110109](S0753332220303012)(10.1016/j.biopha.2020.110109)
    Biomedicine & Pharmacotherapy 2022 DOI
  • Tetyana Voloshyna, Natalia Smaglyukova, Timofei Kondratiev, Roy Andre Lyså, Ole Martin Fuskevåg, Aina Westrheim Ravna et al.:
    Effects of perfluorosulfonic acids on P-glycoprotein mediated transport in the intestinal epithelial barrier
    2022
  • Aina Westrheim Ravna :
    UiT-forsker: Lukten av disse kan gi seksuell opphisselse hos menn
    iTromsø 2022
  • Erik Sveberg Dietrichs, Aina Westrheim Ravna :
    Sjokolade: rusmiddel, legemiddel, eller bare nytelsesmiddel
    28. September 2022
  • Aina Westrheim Ravna :
    Er du «sexforelska»? Heftige krefter, spesielt for kvinner.
    27. November 2021
  • Aina Westrheim Ravna :
    Ekko samfunnspodden - Lykkepromillen
    18. January 2021
  • Aina Westrheim Ravna :
    Sjokolade er god medisin
    18. December 2020
  • Aina Westrheim Ravna :
    Lene ble endelig kvitt søtsuget / Finnes sukkeravhengighet?
    31. July 2020
  • Aina Westrheim Ravna :
    Sukker er et rusmiddel for hjernen
    2020
  • Aina Westrheim Ravna :
    Intervjuet Willoch i kokainrus
    12. September 2020
  • Aina Westrheim Ravna :
    Dette skjer med hjernen din når du bruker sosiale medier
    Nettavisen 2020
  • Aina Westrheim Ravna :
    Ja, du kan bli avhengig av sukker. Men ved hjelp av noen enkle grep kan du komme deg ut av det. (https://www.kk.no/helse/ja-du-kan-bli-avhengig-av-sukker/70914228)
    30. March 2019
  • Aina Westrheim Ravna :
    DRUGS OF ABUSE: Molecular Mechanisms of Action and Potentials for Discovery of New Therapeutics
    2019
  • Aina Westrheim Ravna :
    Avliver sukkermyte: - Ikke bedre humør (https://www.dagbladet.no/mat/avliver-sukkermyte---ikke-bedre-humor/71012699)
    08. May 2019
  • Aina Westrheim Ravna :
    Slik lurer kroppen din deg: - En forelskelse er en felle fra naturens side (https://www.nettavisen.no/livsstil/slik-lurer-kroppen-din-deg---en-forelskelse-er-en-felle-fra-naturens-side/3423833822.html)
    24. August 2019
  • Aina Westrheim Ravna :
    Hva skjer? · Hva skjer med juletradisjonene? (https://radio.nrk.no/serie/hva-skjere/DNRR62003618/23-12-2018#t=29m58.56s)
    23. December 2018
  • Aina Westrheim Ravna :
    En voldsmann blir til
    24. November 2018
  • Aina Westrheim Ravna, Georg Sager :
    Lørdagsuniversitetet: Drug design på data’n
    2017
  • Aina Westrheim Ravna :
    Sukkeravhengighet
    Aktuell Nordisk odontologi 2017 DOI
  • Aina Westrheim Ravna, Georg Sager, Ole-Martin Fuskevåg :
    Når kjemien stemmer
    26. September 2017
  • Aina Westrheim Ravna :
    Forskerne krangler om sukkeravhengighet (https://forskning.no/alkohol-og-narkotika-mat-og-helse-hjernen-overvekt/2017/09/krangler-om-sukkeravhengighet)
    04. September 2017
  • Aina Westrheim Ravna :
    Derfor blir vi hekta på dårlige forhold (http://www.kk.no/samliv/derfor-blir-vi-hekta-pa-darlige-forhold-68561791)
    14. June 2017

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    CV

    EDUCATION AND RESEARCH

    1988    Student at the Los Altos High School, Los Altos, CA, USA.

    1991    Examen artium 1991 from Kongsbakken Videregående Skole, Tromsø.

    1996    Cand.mag. (mathematic-natural scientific), University of Tromsø autumn with exams from the University of Copenhagen, 1995, fitted into cand.mag. degree: Inorganic Chemistry, Valence Theory (Introduction to fundamental conceptions of quantum mechanics) and Physical Organic Chemistry.

    1997    Maternity leave

    1999    Cand.scient., University of Tromsø.

    2000→Teaching pharmacology for of medical students, odontology students, biology studentsat bachelor-, master and doctorate level, and student nurses.

    2000→Supervision of master students, bachelor students and medical students.

    2003    Dr.scient. (PhD), University of Tromsø, 17th October 2003. Title of thesis: ”Molecular modelling of secondary transporters and their interactions with cocaine and SSRIs”.

    Exams from the University of Tromsø included in the dr.scient degree:

    FA-333                 Pharmacokinetics

    K-342                  Protein structure

    BIO-481                Basis course in Biomedical Research

    Exams from the University of Oslo included in the dr.scient degree:

    O-3768                 Mechanisms of Cellular Signal Transduction

    (dissertation completed 9 months ahead of scholarship ending)

    2004    “Universitetspedagogisk seminar” (UPS) at the University of Tromsø.

    2004    Temporary scholarship from the University of Tromsø (autumn 2004)

    2005-2009 Post.doc position granted by The Norwegian Cancer Society doing research on ABC transporters

    2007    Maternity leave

    2008→Supervision of Ph.D. students.

    2009    Research stay at Ruben Abagyan's lab (Molsoft/The Scripps Research Institute, La Jolla, USA) (7 weeks).

    2009→Researcher position at the University of Tromsø (permanent position from February 2011)

    2011    Research stay at Ruben Abagyan's lab  (University of California (UCSD), La Jolla, USA) (3   months)

    Teaching

    Lectures given at the University of Tromsø:

    • Course for specialization in Clinical Pharmacology (Den norske lægeforening):

    o “Neurotransmitter transporters”, 1 hour, spring 2009.

    o “Pharmacological Mechanisms”, 1 hour, 2004, 2006 and 2009.

    o “Molecular modeling as a tool for development of novel drugs”, 1 hour autumn

    2006 and 2009.

    • CNS pharmacology

    o Odontology students, 11 hours, spring 2009.

    o Medical students, 2 hours, spring 2009.

    • Pharmacology for “medisin grunnfag”, 6 hours, autumn 2002 and 2003.

    • Bio-354 (Pharmacology and Toxicology), 9 hours, autumn 2000, 2001, 2002, 2008.

    • Bio-262 (General and Human Toxicology), 10 hours, spring 2001, 2002 and 2003.

    • Bio-2301 (General Pharmacology and Toxicology), 12 hours, spring 2004. (Course

    responsible).

    • Bio-3305 (Toxicology), 6 hours, spring 2004.

    • Bio-8305 (Research frontiers in molecular and structural biology): 1 hour (”The

    homology modeling approach”), autumn 2006.

    • Workshop: ”Introduction to molecular modelling”, 1 hour (“Homology based modelling

    of drug targets”), autumn 2005.

    • Sami traditional medicine for

    o Medical students, spring 2005, 2009 and 2010.

    o Bio2301 students, spring 2004, 2005, 2006, 2008 and 2009.

    o Students enrolled in master study of indigenous people, autumn 2005, spring

    2007, and spring 2009.

     

    Lectures given at Tromsø University College:

    • Pharmacology for student nurses, 4 hours, spring 2002 and spring 2011.

     

    Supervision:

    • PhD students Lena Aronsen, Inger Lindin and Mari Gabrielsen.

    • Master student Elin Øien Ørvoll.

    • Supervision assistance of master students Maja Karlsen Linchausen and Marit Livik.

    • Supervision assistance of medical student at summer stipend, University of Tromsø, 8

    weeks, summer 2000.

    • Supervision of students on semester projects in the course Bio-2301 (General

    Pharmacology and Toxicology) spring 2004 and spring 2010.

    • Training of master- and doctoral students in use of software for molecular modeling and

    computational chemistry at the Department of Pharmacology, Institute of medical

    biology, University of Tromsø.

     

    Colloquium teaching and pharmacokinetic exercises:

    • Pharmacology for medical students (Course I, Introduction to Biological Medicine,

    Pharmacology), 8 hours, autumn 2000, 2002 and 2003.

    • Bio-354 (Pharmacology/Toxicology), 16 hours, autumn 2002 and 2003.

     

    Maternity leaves

    Maternity leave from the 1st of March 1997 until the 7th of January 1998, and from the 30th of

    July 2007 until the 20th of April 2008.

     

    Other experience

    • Indre Sør-Troms Distriktsmuseum; summer employment as museum assistant in 1990, 1991, 1992, 1993, 1994 and 1995.
    • ”Skaidi - Informasjonsavisa for høyere utdanning i Nord-Norge”; summer employment in 1994 as journalist.
    • Information speech about master studies at the Department of Pharmacology, University ofTromsø, for new students, February 2000.
    • External examiner at “Medisin grunnfag” exam spring 2002.
    • Member of two judging committees; employment of PhD student at the Department of Molecular Biotechnology, IMB, University of Tromsø, spring 2002, and employment of PhD student at the Department of Pharmacology, IMB, University of Tromsø, autumn 2003.
    • Responsible for social activities during the course for specialization in ClinicalPharmacology: “Pharmacological Mechanisms” (Den norske lægeforening), February 2004.
    • Preparation of answer to inquiry concerning inquiry note about “Naturmiddelutredningen” from the Ministry of Health in March 2004.
    • Referee for journals (Cellular and Molecular Life Sciences (CMLS), Protein Science, International Journal of Molecular Sciences, Biochemical Pharmacology, Journal of Molecular Modeling, European Journal of Medicinal Chemistry)
    • External examiner at Bio-8305 (Research frontiers in molecular and structural biology), autumn 2006.

    REFERENCES

    Professor Svein Dahl, Institute of Medical Biology, University of Tromsø, phone number 77644704

    Professor Georg Sager, Institute of Medical Biology, University of Tromsø, phone number 77644708

    Professor Ingebrigt Sylte, Institute of Medical Biology, University of Tromsø, phone number 77644705