Bilde av West, Alex
Bilde av West, Alex
Researcher in Chronobiology with the Institute for Arctic and Marine Biology Department of Arctic and Marine Biology alexander.c.west@uit.no +4777645219 Tromsø You can find me here

Alex West



  • Chiara Ciccone, Fayiri Kante, Lars Folkow, David Grey Hazlerigg, Alexander Christopher West, Shona Hiedi Wood :
    Circadian coupling of mitochondria in a deep-diving mammal
    Journal of Experimental Biology 2024 ARKIV / DOI
  • Daniel Appenroth, Alexander Christopher West, Shona Hiedi Wood, David Grey Hazlerigg :
    Tanycytes from a bird’s eye view: gene expression profiling of the tanycytic region under different seasonal states in the Svalbard ptarmigan
    Journal of Comparative Physiology A. Sensory, neural, and behavioral physiology 2024 ARKIV / DOI
  • Daniel Appenroth, Chandra Sekhar Ravuri, Sara Torppa, Shona Hiedi Wood, David Grey Hazlerigg, Alexander Christopher West :
    The Reindeer Circadian Clock Is Rhythmic and Temperature-compensated But Shows Evidence of Weak Coupling Between the Secondary and Core Molecular Clock Loops
    Journal of Biological Rhythms 2024 ARKIV / DOI
  • David Grey Hazlerigg, Barbara Mizumo Tomotani, Alexander Christopher West, Daniel Appenroth, Shona Hiedi Wood :
    Biological timekeeping in polar environments: lessons from terrestrial vertebrates
    Journal of Experimental Biology 2023 ARKIV / DOI
  • Chiara Ciccone, Fayiri Kante, Lars Folkow, David Grey Hazlerigg, Alexander Christopher West, Shona Hiedi Wood :
    Circadian coupling of mitochondria in a deep-diving mammal
    bioRxiv 2023 DOI
  • Daniel Appenroth, Gabriela Wagner, David Hazlerigg, Alexander Christopher West :
    Evidence for circadian-based photoperiodic timekeeping in Svalbard ptarmigan, the northernmost resident bird
    Current Biology 21. June 2021 ARKIV / DOI
  • Alexander Christopher West, Yasutaka Mizoro, Shona Wood, Louise M. Ince, Marianne Iversen, Even Hjalmar Jørgensen et al.:
    Immunologic Profiling of the Atlantic Salmon Gill by Single Nuclei Transcriptomics
    Frontiers in Immunology 2021 ARKIV / DOI
  • Marianne Iversen, Teshome Dagne Mulugeta, Alexander Christopher West, Even Hjalmar Jørgensen, Samuel A. M. Martin, Simen Rød Sandve et al.:
    Photoperiod-dependent developmental reprogramming of the transcriptional response to seawater entry in Atlantic salmon (Salmo salar)
    G3: Genes, Genomes, Genetics 2021 ARKIV / DOI
  • Marianne Iversen, Teshome Dagne Mulugeta, Børge Gellein Blikeng, Alexander Christopher West, Even Hjalmar Jørgensen, Simen Rød Sandve et al.:
    RNA profiling identifies novel, photoperiodhistory dependent markers associated with enhanced saltwater performance in juvenile Atlantic salmon
    PLOS ONE 2020 ARKIV / DOI
  • Daniel Appenroth, Vebjørn Jacobsen Melum, Alexander Christopher West, Hugues Dardente, David Hazlerigg, Gabriela Wagner :
    Photoperiodic induction without light-mediated circadian entrainment in a High Arctic resident bird
    Journal of Experimental Biology 21. August 2020 ARKIV / DOI
  • Alexander Christopher West, Yasutaka Mizoro, Shona Hiedi Wood, Marianne Iversen, Louise Ince, Even Jørgensen et al.:
    A single nuclei transcriptomic analysis of the Atlantic salmon gill through smoltification and seawater transfer
    bioRxiv 2020 DOI
  • Alexander Christopher West, Marianne Iversen, Even Hjalmar Jørgensen, Simen Rød Sandve, David Hazlerigg, Shona Hiedi Wood :
    Diversified regulation of circadian clock gene expression following whole genome duplication
    PLoS Genetics 2020 ARKIV / DOI
  • Shona Hiedi Wood, Alexander Christopher West :
    Seasonal physiology: making the future a thing of the past
    Current Opinion in Physiology 2018 DOI
  • Alexander Christopher West, Laura Smith, David Ray, Andrew S.I. Loudon, Tim Brown, David A. Bechtold :
    Misalignment with the external light environment drives metabolic and cardiac dysfunction
    Nature Communications 2017 DOI
  • Alexander Christopher West, David A. Bechtold :
    The cost of circadian desynchrony: Evidence, insights and open questions
    Bioessays 2015 DOI
  • Lauren Walmsley, Lydia Hanna, Josh Mouland, Franck Marshall, Alexander Christopher West, Andrew R.D. Smedley et al.:
    Colour as a signal for entraining the mammalian circadian clock
    PLoS Biology 2015 DOI
  • Violetta Pilorz, Peter Cunningham, Anthony Jackson, Alexander Christopher West, Travis Wager, Andrew S.I. Loudon et al.:
    A Novel Mechanism Controlling Resetting Speed of the Circadian Clock to Environmental Stimuli
    Current Biology 2014 DOI
  • Alexander Christopher West, Sandrine M Dupre, Le Yu, Robert Patton, K Miedzinska, Alan McNeilly et al.:
    Npas4 Is Activated by Melatonin, and Drives the Clock Gene Cry1 in the Ovine Pars Tuberalis
    Molecular Endocrinology 2013 DOI
  • Chiara Ciccone, Fayiri Kante, David Grey Hazlerigg, Lars Folkow, Alexander Christopher West, Shona Hiedi Wood :
    Circadian clockwork and mitochondrial metabolism in a diving mammal: a link between hypoxia tolerance and time of the day
    2022
  • Alexander Christopher West, David Hazlerigg, Gabrielle Grenier :
    Calendar Timing in Teleost Fish
    Springer Nature 2021 DOI

  • The 50 latest publications is shown on this page. See all publications in Cristin here →

    Publications outside Cristin

    Publications from the last five years:

    • Appenroth D, Ravuri CS, Torppa SK, Wood SH, Hazlerigg DG, West AC (2024) The reindeer circadian clock is rhythmic and temperature-compensated but shows evidence of weak coupling between the secondary and core molecular clock loops. Journal of Biological Rhythms, 39(6), 554-567. 
    • Appenroth D, West AC, Wood SH, Hazlerigg DG (2024) Tanycytes from a bird's eye view: gene expression profiling of the tanycytic region under different seasonal states in the Svalbard ptarmigan. Journal of Comparative Physiology A, 1-13. 
    • Ciccone C, Kante F, Folkow LP, Hazlerigg DG, West AC, Wood SH (2024) Circadian coupling of mitochondria in a deep-diving mammal. Journal of Experimental Biology, 226(23), jeb246308. 
    • Hazlerigg DG, Appenroth D, Tomotani B, West AC, Wood SH (2023) Biological timekeeping in polar environments: lessons from terrestrial vertebrates. Journal of Experimental Biology. 226 (23), jeb246308.
    • Appenroth D, Wagner G, Hazlerigg DG, West AC (2021) Evidence for circadian-based photoperiodic timekeeping in Svalbard ptarmigan, the northernmost resident bird. Current Biology, 31, 2720–2727. 
    • West AC, Mizoro Y, Wood SH, Ince L, Iversen M, Jørgensen E, Nome T, Sandve SR, Loudon ASI, Hazlerigg DG (2021) Immunologic Profiling of the Atlantic Salmon Gill by Single Nuclei Transcriptomics. Frontiers in Immunology, 4(12), 669889.


    Research interests

    The most interesting animals transform their physiology to cope/exploit seasonal changes in their environment; nowhere is this more apparent than in the Arctic. By combining classical experimental designs with cutting edge tools, my research aims to identify the pathways that control seasonal transformation and explores how biological timekeeping is influenced by the Arctic environment.

    Current projects:

    • Vertebrate seasonal photoneuroendocrinology
    • Photoreception in Atlantic salmon
    • Olfactory Imprinting in Atlantic salmon
    • Arctic circadian clocks

     

    Teaching

    Teaching:

    • BIO-3014: Biological Timekeeping (Co-pilot 2021 and 2024, Pilot 2022-2023)
    • BIO-3030: Extreme Physiology
    • BIO-2002: Animal Physiology
    • BIO-2310: Arctic Biology (-2022)

    PhD Supervision

    • Anna Hofinger (2022-present) - Comparative seasonal biology. Supervisors: Alex West, Shona Wood, David Hazlerigg
    • Therese Solberg (2022-present) - How does the light environment shape circadian clock properties? Supervisors: Barbara Tomotani, Marcel Visser, Kees van Oers, Alex West
    • Jana Kalinova (2021-present) - Photoperiodic control of reproduction in birds. Supervisors: David Hazlerigg, Alex West, Shona Wood
    • Chiara Ciccone (2020-2024) - Molecular adaptations to diving-induced hypoxia. Supervisors: Lars Folkow, Shona Wood, Alex West, David Hazlerigg
    • Daniel Appenroth (2016-2020) - Circadian-based processes in the High Arctic: activity, thermoregulation and photoperiodism in the Svalbard ptarmigan (Lagopus muta hyperborea). Supervisors: David Hazlerigg, Gabriela Wagner, Alex West
    • Masters Supervision
    • Sophia Goldena Gunther (2024-present) Olfactory imprinting in Atlantic salmon. Supervisors: Alex West, Anna Hofinger
    • Sigrid Vold Jensen (2023-2024) The role of MCT transporters in hypoxia tolerance of hooded seals. Supervisors: Lars Folkow, Chiara Ciccone, Alex West, Fredrik Andreas Fasth Markussen​
    • Sona Hakhverdyan (2022-2023) - In vivo CRISPR of CUZD1 in Atlantic salmon. Supervisors: Alex West, Helge Tveiten
    • Therese Solberg (2021-2022) - Circadian disruption by light and its effect on the immune function of the Atlantic salmon (Salmo salar). Supervisors: Alex West, Eva-Stina Edholm, David Hazlerigg
    • Anna Hofinger (2020-2021) - Characterization of the biological clock in Svalbard ptarmigan (Lagopus muta hyperborea). Supervisors: David Hazlerigg, Alex West
    • Fayiri Kante (2020-2021) - Characterization of the circadian clock in Hooded Seals (Cystophora Cristata) and its interaction with mitochondrial metabolism: A multi-tissue comparison and cell culture approach. Supervisors: Shona Wood, Alex West
    • Vebjørn Melum (2017-2018) - Influence of photoperiod on central appetite regulation in captive Svalbard rock ptarmigan (Lagopus muta hyperborea) 
    • Nora Slåttebrekk (2017-2018) - An analysis of key molecular clock components in reindeer (Rangifer t. tarandus). Supervisors: Gabriela Wagner, Alex West, David Hazlerigg




    Attachments:

    • CV (docx)