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Bilde av Sajib, Saikat Das
Bilde av Sajib, Saikat Das
Researcher Department of Medical Biology saikat.d.sajib@uit.no Tromsø You can find me here

Saikat Das Sajib

Job description

Researcher | Computational Cancer Biology, Spatial Omics & Proteoglycan Biology

I study tumor heterogeneity, cellular plasticity, the tumor microenvironment, and proteoglycan biology in breast cancer using computational and spatial approaches.

My work includes bulk and single-cell RNA sequencing, spatial transcriptomics, spatial proteomics, and analysis of clinically annotated cancer cohorts. A major focus of my research has been epithelial–mesenchymal plasticity and how cancer-cell states are shaped by developmental programs and interactions with stromal and immune components of the tumor microenvironment. I am also interested in proteoglycans and glycosaminoglycan-associated biology, particularly their spatial organization and roles in tumor-stroma and tumor-immune interactions.

My research is highly collaborative and often involves integrating complex molecular, spatial, and clinical datasets across multidisciplinary projects. I also have a strong interest in teaching, student supervision, and scientific communication, combining computational and experimental perspectives in cancer research and education.

  • Isaac Odonkor, Birendra Kumar Shrestha, Stephanie Rose Nielsen, Athanasios Kournoutis, Ida Emilie Bjørlo, Saikat Das Sajib et al.:
    Stress-specific NONO interactomes reveal a key role of Hsp70 chaperone activity in regulation of paraspeckle formation
    Journal of Cell Science 15. January 2026 DOI / ARKIV
  • Shirin Porteymour, Saikat Das Sajib, Susannah von Hofsten, Atanaska I. Doncheva, Christina D. Bjørnvall, Beate Hegge et al.:
    Serglycin modulates inflammation and metabolism in macrophages
    iScience 10. March 2026 DOI / ARKIV
  • Marek Feith, Saikat Das Sajib, Anne-Grethe Myrann, Anders Høgset, Pablo Garrido, Alfredo Martinez et al.:
    Induction of Cell Death by Combined Treatment with Photosensitizer-Chitosan Nanoparticles and the Ferroptosis Inducer RSL3 in Breast Cancer Cell Lines
    Advanced NanoBiomed Research 2025 DOI / ARKIV
  • Saikat Das Sajib, Md Jubayer al Hossain, Mrinal Kumar Das :
    Stem Cell-Based Regenerative Medicine Therapy in Cancer
    2024 DOI / ARKIV
  • Erik Knutsen, Saikat Das Sajib, Tonje Fiskaa, James Bradley Lorens, Thorarinn Gudjonsson, Gunhild Mari Mælandsmo et al.:
    Identification of a core EMT signature that separates basal-like breast cancers into partial- and post-EMT subtypes
    Frontiers in Oncology 2023 DOI / ARKIV / ARKIV / ARKIV
  • Md Soyib Hasan, Shiful Islam, Md Nazmul Hasan, Saikat Das Sajib, Shamim Ahmed, Tahmina Islam et al.:
    Genome-wide analysis and transcript profiling identify several abiotic and biotic stress-responsive Glutathione S-transferase genes in soybean
    Plant Gene 2020 DOI / ARKIV
  • Shiful Islam, Saikat Das Sajib, Zakya Sultana Jui, Shatil Arabia, Tahmina Islam, Ajit Ghosh :
    Genome-wide identification of glutathione S-transferase gene family in pepper, its classification, and expression profiling under different anatomical and environmental conditions
    Scientific Reports 2019 DOI / ARKIV
  • Saikat Das Sajib, Erik Knutsen :
    Breast Cancer Plasticity and Microenvironmental Dynamics: A Mammary and Developmental Perspective on EMT Heterogeneity
    UiT Norges arktiske universitet 20. February 2026 ARKIV
  • Kjersti Sellæg, Susannah von Hofsten, Saikat Das Sajib, Karoline Sollid Evensen, Beate Hegge, Margrethe Similä Vasslag et al.:
    Hva gjør en kreftforsker?
    2025 ARKIV
  • Kjersti Sellæg, Tetyana Voloshyna, Saikat Das Sajib, Tonje Nygård Lillevik, Susannah Beatrice von Hofsten, Karoline Sollid Evensen et al.:
    Urinlaben
    2024 ARKIV
  • Saikat Das Sajib, Åse Florholmen-Kjær, Vegard Brun, Elin Synnøve Mortensen, Aud-Malin Karlsson Hovd, Xavier Tekpli et al.:
    Epithelial-to-mesenchymal transition (EMT) is a major contributor to intratumor heterogeneity in lymph node metastasis in breast cancer
    2023 ARKIV
  • Anne Kristin Mclaren Berge, Kjersti Sellæg, Stine Figenschau, Saikat Das Sajib, Hallvard Lauritz Olsvik, Maria Perander et al.:
    TRIM32 in Head and Neck Cancer
    2023 ARKIV

    • The 50 latest publications is shown on this page. See all publications in NVA here →

    Research interests

    • Breast cancer biology and metastasis
    • Tumor heterogeneity and cellular plasticity
    • Epithelial–mesenchymal plasticity
    • Tumor microenvironment and immune–tumor interactions
    • Proteoglycan and glycosaminoglycan biology
    • Spatial biology and spatial omics
    • Single-cell and bulk transcriptomics
    • Computational cancer biology and bioinformatics
    • Biomarker discovery and clinically annotated cancer cohorts
    ResearchGate
    ORCID: https://orcid.org/0000-0002-8363-7941

    Member of research group / centre

    Tumor Biology Research Group   English content

    Member of project

    Breast cancer
    MH øst L8.229


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