Trained innate immunity of fish larvae

The general understanding has been that only adaptive immunity is capable of immunological memory, but this concept has been challenged in recent years by studies showing that innate immune systems can mount resistance to reinfection - as the innate immune system can adapt its function following an insult. 

Innate immune training offers an attractive approach in intensive fish larval rearing, especially since the adaptive immune system is not fully developed. Trained innate immunity will potentially favor robust fish in terms of resistance to viral and bacterial diseases. In this project, we will look at how in practical terms and based on prior knowledge one can introduce innate immune training in larval aquaculture. PI: Roy A. Dalmo. Master student: Harald Kristoffersen.
Uptake of bacterial lipopolysaccharide in yolk sac larvae Foto: Roy A. Dalmo


Responsible: Roy Ambli Dalmo

Harald Kristoffersen