Disputas – master in medicine Ieva Martinaityte

Master in medicine Ieva Martinaityte disputerer for ph.d.-graden i helsevitenskap og vil offentlig forsvare avhandlingen:

“Storage of vitamin D in adipose tissue and associations between vitamin D related genetic variants and diabetes, myocardial infarction, cancer, death, and low bone mineral density. Results from a high-dose vitamin D study and the Tromsø Study”

Kort sammendrag av avhandlingen:

Vitamin D is a hormone, found in most of tissues and organs. Vitamin D modifies about 3% of human genes, and also acts directly in cells. In addition to the essential role of maintaining bone health, vitamin D is also believed to be important in boosting the immune system, regulating processes in fat tissue, and preventing certain negative health outcomes.

In our project, we found that vitamin D supplementation for 3–5 years maintained sufficient serum vitamin D levels the following year after cessation, likely due to storage of vitamin D in fat tissue. In addition, we investigated if there were any gene variations related to vitamin D and estrogen, which could increase the risk of negative health outcomes, including cancer and death. We found that certain vitamin D and estrogen related genes could increase the risk of type 2 diabetes, myocardial infarction (rs7968585) and low bone mineral mass (rs4870044 and rs6013897) in our population from Tromsø, Northern Norway.(Avhandlingen er tilgjengelig for utlån hos Seksjon forutdanningstjenester frem til disputasdato)

Hovedveileder førsteamanuensis Elena Kamycheva, Institutt for klinisk medisin, UiT – Norges arktiske universitet

Biveileder professor Rolf Jorde, Institutt for klinisk medisin, UiT – Norges arktiske universitet


Professor Stefan Pilz, Medical University of Graz, Graz, Østerrike – 1.opponent

Professor Kirsten Bjørklund Holven, Institutt for medisinske basalfag, Universitetet i Oslo – 2. opponent

Professor II Bjørn Odvar Eriksen, Institutt for klinisk medisin, UiT- Norges arktiske universitet – leder av komite

Professor Roy Bremnes, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, Universitetet i Tromsø – Norges arktiske universitet


Prøveforelesning over oppgitt emne holdes kl. 10.15, samme sted: Calcium intake and health outcomes: who should take calcium supplements?”

When: 22.03.18 at 12.15–16.00
Where: Tabletten - Farmasibygget
Location / Campus: Tromsø
Target group: All
Responsible: Ingrid Kvist Martinussen
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